Simply Ammy
Simply Ammy
@ammyli.bsky.social
Enjoys nature, art, music, humor. Despises gas leaf blowers. Has a thing for Peanuts comics, turtles, and sasquatch
Reposted by Simply Ammy
A peptide inhibitor selectively blocks the ATAC histone complex by targets the YEATS2 YEATS domain and suppresses tumor growth in non-small cell lung cancer

www.nature.com/articles/s41...
Complex-specific inhibitors for interrogating ATAC histone acetyltransferase complex - Nature Chemical Biology
Liu, Liu, Wu and Yao et al. developed a peptide inhibitor that selectively blocks the Ada-two-A-containing histone complex by targeting the YEATS2 YEATS domain and suppresses tumor growth in non-small...
www.nature.com
January 16, 2026 at 8:43 PM
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Using activity-based chemical probes, oncogenic IDH1-R132H but not the WT was found to acquire a unique autopalmitoylation at C269 that is critical for the enzyme’s abnormal activity in cancer

www.nature.com/articles/s41...
Autopalmitoylation of IDH1-R132H regulates its neomorphic activity in cancer cells - Nature Chemical Biology
Using activity-based chemical probes, oncogenic IDH1-R132H but not the wild type was found to acquire a unique autopalmitoylation at C269. This mutant-specific modification is critical for the enzyme’...
www.nature.com
January 16, 2026 at 8:44 PM
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🚨 NEW RESEARCH! ⚕️ 🩺

Kim et al. investigate the behavioral and neural markers of adolescent impulsivity and find key functional connectivity differences.

https://bit.ly/4jncTkY
#AdolescentHealth
The role of the salience network in adolescent impulsivity using memory tasks and neuroimaging - Communications Medicine
Kim et al. investigate behavioral and neural markers of adolescent impulsivity using memory tasks and resting state fMRI. Stronger functional connections between the brain’s salience network, including the insula and dorsal anterior cingulate, and the locus coeruleus serve as a neural indicator of higher impulsivity in teenagers.
bit.ly
January 5, 2026 at 1:02 PM
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Steves purchased the property to prevent it from closing. Many homeless people had come to depend on the Lynnwood Hygiene Center, which had operated rent-free on the property since 2020. n.pr/3MKbmJH
Rick Steves steps in to save Seattle-area hygiene center serving homeless residents
Steves purchased the property to prevent it from closing. Many homeless people had come to depend on the Lynnwood Hygiene Center, which had operated rent-free on the property since 2020.
n.pr
December 22, 2025 at 6:20 AM
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The December issue is now complete and fully online:

www.nature.com/nplants/volu...
December 18, 2025 at 11:03 AM
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Our editors write:

- Plant genetics: The pan-genomics path to drought-resistant maize rdcu.be/eSK8o

- Barley domestication: Sprouting at the right time rdcu.be/eSK8y

- Heat tolerance: A novel player in selective autophagy rdcu.be/eSK8Q
December 2, 2025 at 12:16 PM
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Montage of 19 clips of Trump insulting, berating, demeaning and attacking female reporters over the past few months. Part 1.
November 19, 2025 at 1:13 PM
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Aging Tumor Microenvironment Fuels Cancer Risk: Genetic and Epigenetic Changes Elevate Clonal Expansion Post-50, Paving Path for New Therapies.

by Easwaran H and Weeraratna AT in Nat Rev Cancer #MedSky

👉 get more here

📖 read the article:
Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer - Nature Reviews Cancer
In this Review, Easwaran and Weeraratna outline how ageing leads to epigenetic alterations in the tissue microenvironment, enhancing clonal expansion of mutations and ultimately increasing cancer risk.
www.nature.com
November 10, 2025 at 6:43 PM
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From research to real-world benefits – a new feature of our articles to highlight real-world benefits of research

Here, @sarannafanning.bsky.social and Dennis Selkoe explain the implications of understanding lipid homeostasis in Parkinson disease.

Full article here: nature.com/articles/s41...
November 6, 2025 at 12:32 PM
The time of day I get the best and most relaxing, recovering sleep.... Is unfortunately the time of day I'm expected to be waking up to go to work. Sigh
October 27, 2025 at 12:18 PM
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gene kelly is antifa
October 14, 2025 at 12:07 AM
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Data from a large, ongoing study of adolescents shows a link between increasing social media use and lower cognition and memory in teens.
Kids who use social media score lower on reading and memory tests, a study shows
Data from a large, ongoing study of adolescents shows a link between increasing social media use and lower cognition and memory in teens.
n.pr
October 14, 2025 at 11:44 AM
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#Throwback 🧪

REVIEW | Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

@elizschneider.bsky.social‬
@jfcryan.bsky.social et al
Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis - Nature Metabolism
This Review provides an overview of the interplay between host diet and the gut microbiota, and how this affects brain function.
bit.ly
October 1, 2025 at 3:22 PM
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The world’s only museum dedicated to contraception and abortion is marking 22 years since its opening in Vienna. Founded by Austrian gynecologist Christian Fiala, the Museum of Contraception and Abortion highlights the struggle for fertility control and the importance of safe access to abortion.
World’s only abortion museum marks 22 years defending reproductive freedom - EFE
By Núria Morchón Vienna, Sep. 28 (EFE).— The world’s only museum dedicated to contraception and abortion is marking 22 years since its opening in Vienna, continuing to educate new generations on repro...
efe.com
September 29, 2025 at 2:28 AM
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"A 3D printable bio-active glass could be used to repair bone damage and help them grow back, a study suggests." www.newsweek.com/scientists-c...
Scientists Can Now 3D Print Glass To Help Bones Grow Back
bones
www.newsweek.com
September 28, 2025 at 4:23 PM
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If you read one thing today #Cansky make it this, and share it as much as you can. #Oncsky #Medsky

www.nytimes.com/2025/09/14/m...
Trump Is Shutting Down the War On Cancer
www.nytimes.com
September 14, 2025 at 10:01 PM
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Things you should never do to introverts:

1. Show up to our homes unexpectedly.
2. Interrupt our recharge time.
3. Invite people to the outing without telling us.
4. Call us right after we texted you.
5. Ask us “why are you so quiet?”
September 21, 2025 at 4:27 PM
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A Review in Nature Reviews Rheumatology discusses how alterations in the gut are linked to the development of arthritis. The authors challenge the concept of the ‘leaky gut’ hypothesis. 🔒
More than a leaky gut: how gut priming shapes arthritis - Nature Reviews Rheumatology
This Review discusses how alterations in the gut are linked to the development of arthritis. The authors challenge the concept of the ‘leaky gut’ hypothesis, stating that the effects of intestinal permeability and bacterial translocation on the immune system are distinct.
go.nature.com
September 19, 2025 at 10:17 PM
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September 13, 2025 at 3:06 PM
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I don’t answer my phone but I sure will text you “what’s up” right after you call me
September 9, 2025 at 5:26 PM