Aleesa Schlientz
@aleesaschlientz.bsky.social
Postdoctoral scholar @ Oegema/Desai labs, UC San Diego | Bowerman lab & UOregon alumna | Dungeons and Dragons Enthusiast | Painter of Tiny Things | she/her
Reposted by Aleesa Schlientz
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
Reposted by Aleesa Schlientz
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
Reposted by Aleesa Schlientz
A chromatin-associated pool of Aurora A controls kinetochore-microtubule attachments to ensure chromosome biorientation https://www.biorxiv.org/content/10.1101/2025.10.31.685952v1
November 1, 2025 at 5:30 PM
A chromatin-associated pool of Aurora A controls kinetochore-microtubule attachments to ensure chromosome biorientation https://www.biorxiv.org/content/10.1101/2025.10.31.685952v1
Reposted by Aleesa Schlientz
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 4:36 PM
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Reposted by Aleesa Schlientz
New paper from the lab! Many animal cells exhibit chiral cell surface dynamics, which are proposed to drive left–right asymmetric patterning. However, the molecular mechanisms linking these events remain unclear. authors.elsevier.com/a/1l%7E7B3QW...
authors.elsevier.com
October 22, 2025 at 5:27 PM
New paper from the lab! Many animal cells exhibit chiral cell surface dynamics, which are proposed to drive left–right asymmetric patterning. However, the molecular mechanisms linking these events remain unclear. authors.elsevier.com/a/1l%7E7B3QW...
Reposted by Aleesa Schlientz
Dear all, A scientist from UNC Chapel Hill, Paul Maddox, is running for congress in NC for a seat currently held by a republican. If you care about science (and democracy) please consider donating to his campaign #Standupforscience secure.actblue.com/donate/paul-...
Donate to Paul Maddox for Congress in NC 11
Paul is running for Congress because there’s a sickness in Washington, and no one is working to cure it.
secure.actblue.com
October 20, 2025 at 5:51 PM
Dear all, A scientist from UNC Chapel Hill, Paul Maddox, is running for congress in NC for a seat currently held by a republican. If you care about science (and democracy) please consider donating to his campaign #Standupforscience secure.actblue.com/donate/paul-...
Reposted by Aleesa Schlientz
.@austinseroka1.bsky.social of Fred Hutchinson Cancer Center will kick off the #SDBPostdocSeminar with his talk "Transcription factor code specifies vagal motor innervation of organ targets during development" Image: Vagal axons extending towards organ targets during development
October 8, 2025 at 7:12 PM
.@austinseroka1.bsky.social of Fred Hutchinson Cancer Center will kick off the #SDBPostdocSeminar with his talk "Transcription factor code specifies vagal motor innervation of organ targets during development" Image: Vagal axons extending towards organ targets during development
Reposted by Aleesa Schlientz
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
October 2, 2025 at 11:00 AM
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
Reposted by Aleesa Schlientz
Now out on bioRxiv. 🥳My research on #cytokinesis, averaging thousands of #ExM images🔬, creating a dynamic atlas of cytokinesis 🦠⏳. Here's an animated sneak peek of what we found. Better resolution on bioRxiv😄 #PSFoftheGIF
September 28, 2025 at 2:15 PM
Now out on bioRxiv. 🥳My research on #cytokinesis, averaging thousands of #ExM images🔬, creating a dynamic atlas of cytokinesis 🦠⏳. Here's an animated sneak peek of what we found. Better resolution on bioRxiv😄 #PSFoftheGIF
Reposted by Aleesa Schlientz
1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.
September 19, 2025 at 4:25 PM
1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.
Reposted by Aleesa Schlientz
I am honored to be selected as a winner of a 2025 MBoC Early-Career Paper Award for my recent work on the role of kinetochores in establishing neuronal architecture. Thank you to my supervisor @dcheerambathur.bsky.social and co-authors! @ascbiology.bsky.social
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
September 12, 2025 at 2:14 PM
I am honored to be selected as a winner of a 2025 MBoC Early-Career Paper Award for my recent work on the role of kinetochores in establishing neuronal architecture. Thank you to my supervisor @dcheerambathur.bsky.social and co-authors! @ascbiology.bsky.social
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
Reposted by Aleesa Schlientz
Our recent study exploring the mechanisms behind hybrid incompatibility in Caenorhabditis Elegans nematodes is now available at @currentbiology.bsky.social!
Many thanks to my collaborators at UCSD - @odlab.bsky.social @greenbeegreen.bsky.social and the Rifkin Lab!
www.cell.com/current-biol...
Many thanks to my collaborators at UCSD - @odlab.bsky.social @greenbeegreen.bsky.social and the Rifkin Lab!
www.cell.com/current-biol...
Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos
Bloom et al. show that hybrid incompatibility between Caenorhabditis elegans group
nematode species pairs arises immediately after fertilization, before zygotic gene
expression. Primary defects in spe...
www.cell.com
July 3, 2025 at 12:10 AM
Our recent study exploring the mechanisms behind hybrid incompatibility in Caenorhabditis Elegans nematodes is now available at @currentbiology.bsky.social!
Many thanks to my collaborators at UCSD - @odlab.bsky.social @greenbeegreen.bsky.social and the Rifkin Lab!
www.cell.com/current-biol...
Many thanks to my collaborators at UCSD - @odlab.bsky.social @greenbeegreen.bsky.social and the Rifkin Lab!
www.cell.com/current-biol...
Reposted by Aleesa Schlientz
How do species remain distinct? Our recent collaboration with the Rifkin Lab discovered a new hybrid incompatibility between Caenorhabditis species that results in defects in the first cell division, like irregular spindles! We show how subtle changes in cell biology can reinforce species barriers.
July 16, 2025 at 5:33 PM
How do species remain distinct? Our recent collaboration with the Rifkin Lab discovered a new hybrid incompatibility between Caenorhabditis species that results in defects in the first cell division, like irregular spindles! We show how subtle changes in cell biology can reinforce species barriers.
Reposted by Aleesa Schlientz
New preprint! Grad student Clover Stubbert and undergrad Cherry Soe worked out a serum-free media that sustains eggshell-less C. elegans embryos all the way through development, now making it possible to access any embryonic developmental stage with small molecules
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Long-term ex ovo culture of Caenorhabditis elegans embryos
The genetic tractability, transparency and invariant development of the C. elegans embryo have led to its broad adoption as a model system for the study of cell and developmental biology. Its impermea...
www.biorxiv.org
June 27, 2025 at 8:21 PM
New preprint! Grad student Clover Stubbert and undergrad Cherry Soe worked out a serum-free media that sustains eggshell-less C. elegans embryos all the way through development, now making it possible to access any embryonic developmental stage with small molecules
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Aleesa Schlientz
The Oegema/Desai labs are heading to #Worm25! Mark your calendars and check out the talks/posters from our current lab members @greenbeegreen.bsky.social @nehavarshney.bsky.social @aleesaschlientz.bsky.social and Wanying Tian!
June 28, 2025 at 8:54 PM
The Oegema/Desai labs are heading to #Worm25! Mark your calendars and check out the talks/posters from our current lab members @greenbeegreen.bsky.social @nehavarshney.bsky.social @aleesaschlientz.bsky.social and Wanying Tian!
Reposted by Aleesa Schlientz
We are excited to share our latest work on the role of anillin during unilateral cytokinesis. Congratulations to Mikhail, the leading author, for his excellent work. Big thanks to the @tdvalilab.bsky.social lab for their tremendous support.
Lebedev et al. @zaninlab.bsky.social @fau.de show that anillin mediates unilateral #cytokinesis by blocking the effector binding site of active RhoA. rupress.org/jcb/article/...
#Development #CellDivision
#Development #CellDivision
April 23, 2025 at 3:05 PM
We are excited to share our latest work on the role of anillin during unilateral cytokinesis. Congratulations to Mikhail, the leading author, for his excellent work. Big thanks to the @tdvalilab.bsky.social lab for their tremendous support.
Reposted by Aleesa Schlientz
Every one of my friends is asking “do I even have a career going forward”
“Our next generation of researchers are now poised on the edge of this cliff, not knowing if there’s going to be a bridge that’s going to get them to the other side, or if this is it”
Musk and Trump are blowing up science careers for every STEM student.
Musk and Trump are blowing up science careers for every STEM student.
Not only are we limiting our medical research and advancement of new treatments, but NIH cuts are affecting ability of universities to take on grad students, limiting our future workforce @altcdc.altgov.info @altnih4science.bsky.social #science #cuts #resist
apnews.com/article/trum...
apnews.com/article/trum...
March 8, 2025 at 2:06 PM
Every one of my friends is asking “do I even have a career going forward”
Reposted by Aleesa Schlientz
A sperm-oocyte protein partnership required for egg activation in Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.01.23.634539v1
January 23, 2025 at 11:31 PM
A sperm-oocyte protein partnership required for egg activation in Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.01.23.634539v1
Reposted by Aleesa Schlientz
Interested in Base Editing and Genetic Screening?
Check out our method chapter: link.springer.com/protocol/10....
Esther Ng did an excellent job developing these methods in our lab. The constructs will soon be available on @addgene.bsky.social
Many thanks to OIST for supporting open access!
Check out our method chapter: link.springer.com/protocol/10....
Esther Ng did an excellent job developing these methods in our lab. The constructs will soon be available on @addgene.bsky.social
Many thanks to OIST for supporting open access!
Genetic Engineering and Screening Using Base Editing and Inducible Gene Knockout
Genetic engineering and screening in human cells are powerful techniques for the precise and comprehensive identification and analysis of gene and protein domain functions. Genome-wide knockout screen...
link.springer.com
December 19, 2024 at 3:03 AM
Interested in Base Editing and Genetic Screening?
Check out our method chapter: link.springer.com/protocol/10....
Esther Ng did an excellent job developing these methods in our lab. The constructs will soon be available on @addgene.bsky.social
Many thanks to OIST for supporting open access!
Check out our method chapter: link.springer.com/protocol/10....
Esther Ng did an excellent job developing these methods in our lab. The constructs will soon be available on @addgene.bsky.social
Many thanks to OIST for supporting open access!
Reposted by Aleesa Schlientz
Check out these PAID summer internships and other opportunities for undergraduates and graduate students.
www.pathwaystoscience.org
www.pathwaystoscience.org
December 17, 2024 at 5:15 PM
Check out these PAID summer internships and other opportunities for undergraduates and graduate students.
www.pathwaystoscience.org
www.pathwaystoscience.org
Reposted by Aleesa Schlientz
Interested in the “mind blowing” 🤯 function of Protein phosphatase 1 beta during C elegans embryonic development!!! Come by my microsymposium talk and poster [B348] today at #cellbio2024!
We couldn't be more excited to present our work at #CellBio2024! Mark your calendars for these talks/posters by our current lab members and recent alumni, including @aleesaschlientz.bsky.social @beatascienceart.bsky.social @nehavarshney.bsky.social & @jiaweixu.bsky.social. Looking forward to it!
December 16, 2024 at 5:12 PM
Interested in the “mind blowing” 🤯 function of Protein phosphatase 1 beta during C elegans embryonic development!!! Come by my microsymposium talk and poster [B348] today at #cellbio2024!
@odlab.bsky.social presentations/posters at #CellBio2024 start today! Cytokinesis folks come find me during the poster session for my back to back posters, and check out Maia Kirkegaard's poster before her presentation in Cytokinesis subgroup part 2!
We couldn't be more excited to present our work at #CellBio2024! Mark your calendars for these talks/posters by our current lab members and recent alumni, including @aleesaschlientz.bsky.social @beatascienceart.bsky.social @nehavarshney.bsky.social & @jiaweixu.bsky.social. Looking forward to it!
December 15, 2024 at 5:44 PM
@odlab.bsky.social presentations/posters at #CellBio2024 start today! Cytokinesis folks come find me during the poster session for my back to back posters, and check out Maia Kirkegaard's poster before her presentation in Cytokinesis subgroup part 2!
Reposted by Aleesa Schlientz
After our #SciArt subgroup at #CellBio2024, join us for a very special Science Art Show & Reception, where you'll get to interact with our amazing speakers and other pioneers in this field. We are honored to feature over 30 scientists/artists in the exhibition! RSVP: beatascienceart.com/artshow2024/
December 14, 2024 at 7:32 PM
After our #SciArt subgroup at #CellBio2024, join us for a very special Science Art Show & Reception, where you'll get to interact with our amazing speakers and other pioneers in this field. We are honored to feature over 30 scientists/artists in the exhibition! RSVP: beatascienceart.com/artshow2024/
Reposted by Aleesa Schlientz
We couldn't be more excited to present our work at #CellBio2024! Mark your calendars for these talks/posters by our current lab members and recent alumni, including @aleesaschlientz.bsky.social @beatascienceart.bsky.social @nehavarshney.bsky.social & @jiaweixu.bsky.social. Looking forward to it!
December 14, 2024 at 2:30 AM
We couldn't be more excited to present our work at #CellBio2024! Mark your calendars for these talks/posters by our current lab members and recent alumni, including @aleesaschlientz.bsky.social @beatascienceart.bsky.social @nehavarshney.bsky.social & @jiaweixu.bsky.social. Looking forward to it!