🦠Winnie Lee🦠
@winnielee.bsky.social
Postdoctoral researcher at Imperial College London | Optimising antimicrobial therapy with the use of AI, modelling and data linkage | Previous research in bacterial genomics
& bioinformatics | Small person studying small things | 🇬🇧🇭🇰
& bioinformatics | Small person studying small things | 🇬🇧🇭🇰
Reposted by 🦠Winnie Lee🦠
Now published! www.nature.com/articles/s41...
Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.
Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.
September 29, 2025 at 2:24 PM
Now published! www.nature.com/articles/s41...
Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.
Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.
Incredible week with @camo-net.bsky.social UK and India! Diving into all things AMR surveillance, data systems and stewardship strageties! Grateful to our hosts at Amrita for having us! 🇬🇧🇮🇳 #globalhealth #AMR
June 18, 2025 at 4:17 PM
Incredible week with @camo-net.bsky.social UK and India! Diving into all things AMR surveillance, data systems and stewardship strageties! Grateful to our hosts at Amrita for having us! 🇬🇧🇮🇳 #globalhealth #AMR
Reposted by 🦠Winnie Lee🦠
Interesting paper
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China
'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one'
www.nature.com/articles/s41...
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China
'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one'
www.nature.com/articles/s41...
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China - Nature Communications
The genomic epidemiology of Acinetobacter baumannii, which is rising in virulence and multidrug resistance, was explored. This study examined bloodstream infection isolates from Chinese patients in 20...
www.nature.com
April 17, 2025 at 8:58 AM
Interesting paper
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China
'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one'
www.nature.com/articles/s41...
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China
'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one'
www.nature.com/articles/s41...
Reposted by 🦠Winnie Lee🦠
Reposted by 🦠Winnie Lee🦠
Discovery of a new class of natural antibiotics with a new mode of action to address antimicrobial resistance, a major unmet need
@mcmasteruniversity.bsky.social
@nature.com
www.nature.com/articles/s41...
@mcmasteruniversity.bsky.social
@nature.com
www.nature.com/articles/s41...
A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome - Nature
A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistanc...
www.nature.com
March 26, 2025 at 5:48 PM
Discovery of a new class of natural antibiotics with a new mode of action to address antimicrobial resistance, a major unmet need
@mcmasteruniversity.bsky.social
@nature.com
www.nature.com/articles/s41...
@mcmasteruniversity.bsky.social
@nature.com
www.nature.com/articles/s41...
Reposted by 🦠Winnie Lee🦠
One week left to apply for this BBSRC funded PhD position in the Duncan lab, cosupervised by @thecopperdoctor.bsky.social and @ruamicro.bsky.social www.findaphd.com/phds/project...
Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University on FindAPhD.com
PhD Project - Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University, listed on FindAPhD.com
www.findaphd.com
March 22, 2025 at 3:57 PM
One week left to apply for this BBSRC funded PhD position in the Duncan lab, cosupervised by @thecopperdoctor.bsky.social and @ruamicro.bsky.social www.findaphd.com/phds/project...
Reposted by 🦠Winnie Lee🦠
Please RT. Post-doc opportunity alert! 💥 Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust.
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
March 28, 2025 at 5:39 PM
Please RT. Post-doc opportunity alert! 💥 Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust.
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
Reposted by 🦠Winnie Lee🦠
I am delighted to update that our work presented at the ICID 2024 has been published today: Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone www.sciencedirect.com/science/arti...
Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone
Healthcare environments have been identified as a significant source of multidrug-resistant bacterial infections, particularly, in vulnerable patients…
www.sciencedirect.com
March 2, 2025 at 11:19 PM
I am delighted to update that our work presented at the ICID 2024 has been published today: Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone www.sciencedirect.com/science/arti...
Reposted by 🦠Winnie Lee🦠
New online! The role of bacterial metabolism in antimicrobial resistance
The role of bacterial metabolism in antimicrobial resistance
Nature Reviews Microbiology, Published online: 20 February 2025; doi:10.1038/s41579-025-01155-0In this Review, Ahmad et al. examine how antibiotics influence bacterial metabolism and how metabolism, in turn, affects drug efficacy and the emergence and…
www.nature.com
February 20, 2025 at 3:12 PM
New online! The role of bacterial metabolism in antimicrobial resistance
Reposted by 🦠Winnie Lee🦠
Reposted by 🦠Winnie Lee🦠
McMaster researchers developed the free ESKAPE Model, an AI tool for identifying new antibiotics against resistant pathogens, allowing researchers to screen up to 20,000 chemicals daily.
How to access is not yet shared, but stay tuned 😊
brighterworld.mcmaster.ca/articles/esk...
How to access is not yet shared, but stay tuned 😊
brighterworld.mcmaster.ca/articles/esk...
McMaster researchers develop and share free antibiotic discovery tool to fight superbugs
Creators of the ESKAPE Model are putting it in scientists' hands now so they can use the tool to do in a moment what otherwise might take weeks, with the goal of accelerating the discovery of new drug...
brighterworld.mcmaster.ca
January 27, 2025 at 6:13 PM
McMaster researchers developed the free ESKAPE Model, an AI tool for identifying new antibiotics against resistant pathogens, allowing researchers to screen up to 20,000 chemicals daily.
How to access is not yet shared, but stay tuned 😊
brighterworld.mcmaster.ca/articles/esk...
How to access is not yet shared, but stay tuned 😊
brighterworld.mcmaster.ca/articles/esk...
Reposted by 🦠Winnie Lee🦠
BIGSdb v1.50.0 has been released, introducing support for registering fields from the output of third-party analysis tools and then using these in queries and analyses (image shows querying hicap results in H. influenzae database).
December 2, 2024 at 10:03 AM
BIGSdb v1.50.0 has been released, introducing support for registering fields from the output of third-party analysis tools and then using these in queries and analyses (image shows querying hicap results in H. influenzae database).
Reposted by 🦠Winnie Lee🦠
🆕Read my short perspective on @daganlab.bsky.social's intriguing @currentbiology.bsky.social paper that examined plasmid-mediated gene mobilisation by comparing plasmid cargoes with chromosomal sequences across almost 2000 isolates, now in Trends in Microbiology 💻💫🧬 #MicroSky
Loading and unloading plasmid cargoes
Plasmids are vehicles for horizontal gene transfer between cells, but they also exchange
genes with associated chromosomes in a process termed 'intracellular mobility'. I
discuss a recent article by K...
www.cell.com
December 3, 2024 at 10:30 PM
🆕Read my short perspective on @daganlab.bsky.social's intriguing @currentbiology.bsky.social paper that examined plasmid-mediated gene mobilisation by comparing plasmid cargoes with chromosomal sequences across almost 2000 isolates, now in Trends in Microbiology 💻💫🧬 #MicroSky
At ISID 2024 to present work with Nina Zhu & Tim Rawson on using AI to predict acute kidney injury from vancomycin & VPT therapy! Visit poster #1 at 12 PM today! @CAMO_Net1 @HPRUamr #AMR #AIinMedicine Also chat to me about Microbiology Society's Knocking out AMR project 😊
December 4, 2024 at 8:32 AM
At ISID 2024 to present work with Nina Zhu & Tim Rawson on using AI to predict acute kidney injury from vancomycin & VPT therapy! Visit poster #1 at 12 PM today! @CAMO_Net1 @HPRUamr #AMR #AIinMedicine Also chat to me about Microbiology Society's Knocking out AMR project 😊
Reposted by 🦠Winnie Lee🦠
JOB CLAXON!
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
Research Fellow - Department of Microbes, Infections and Microbiomes - 104864 - Grade 7
This exciting BBSRC-funded project aims to mechanistically characterise the fitness costs associated with vancomycin resistance in the Gram-positive opportunistic pathogens Enterococcus faecalis and E...
edzz.fa.em3.oraclecloud.com
November 12, 2024 at 10:41 PM
JOB CLAXON!
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
Reposted by 🦠Winnie Lee🦠
Hot off the press - some light reading on Shigella sonnei! 🧪🧫🧬
With @ksbakes.bsky.social @yekwah.bsky.social @sydneylmiles.bsky.social @sergemostowylab.bsky.social @lshtmamrcentre.bsky.social and a bunch of others not yet on bluesky rdcu.be/d1EAF
With @ksbakes.bsky.social @yekwah.bsky.social @sydneylmiles.bsky.social @sergemostowylab.bsky.social @lshtmamrcentre.bsky.social and a bunch of others not yet on bluesky rdcu.be/d1EAF
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Nature Reviews Microbiology - In this Review, Scott et al. review our current knowledge of Shigella sonnei, highlighting recent insights into this globally disseminated antimicrobial-resistant...
rdcu.be
November 27, 2024 at 1:33 PM
Hot off the press - some light reading on Shigella sonnei! 🧪🧫🧬
With @ksbakes.bsky.social @yekwah.bsky.social @sydneylmiles.bsky.social @sergemostowylab.bsky.social @lshtmamrcentre.bsky.social and a bunch of others not yet on bluesky rdcu.be/d1EAF
With @ksbakes.bsky.social @yekwah.bsky.social @sydneylmiles.bsky.social @sergemostowylab.bsky.social @lshtmamrcentre.bsky.social and a bunch of others not yet on bluesky rdcu.be/d1EAF
Reposted by 🦠Winnie Lee🦠
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
November 13, 2024 at 12:46 PM
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
Reposted by 🦠Winnie Lee🦠
HERE's our paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection
dx.plos.org/10.1371/journal.ppat.1012679
Great job to our @Emmabeansworth.bsky.social, @gemma-langridge.bsky.social, @winnielee.bsky.social & UKHSA's Marie Chattaway & Amina Ismail Ahmed
dx.plos.org/10.1371/journal.ppat.1012679
Great job to our @Emmabeansworth.bsky.social, @gemma-langridge.bsky.social, @winnielee.bsky.social & UKHSA's Marie Chattaway & Amina Ismail Ahmed
https://dx.plos.org/10.1371/journa…
November 21, 2024 at 6:03 PM
HERE's our paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection
dx.plos.org/10.1371/journal.ppat.1012679
Great job to our @Emmabeansworth.bsky.social, @gemma-langridge.bsky.social, @winnielee.bsky.social & UKHSA's Marie Chattaway & Amina Ismail Ahmed
dx.plos.org/10.1371/journal.ppat.1012679
Great job to our @Emmabeansworth.bsky.social, @gemma-langridge.bsky.social, @winnielee.bsky.social & UKHSA's Marie Chattaway & Amina Ismail Ahmed
Reposted by 🦠Winnie Lee🦠
Hello Blueskis. Here is a starter pack of General Microbiology. It's a small list currently. Please feel free to self-nominate and I will add you.
go.bsky.app/QgSQHJ9
go.bsky.app/QgSQHJ9
November 12, 2024 at 9:33 PM
Hello Blueskis. Here is a starter pack of General Microbiology. It's a small list currently. Please feel free to self-nominate and I will add you.
go.bsky.app/QgSQHJ9
go.bsky.app/QgSQHJ9
Reposted by 🦠Winnie Lee🦠
PhD studentship available.
The project is VERY interdisciplinary, combing social science, biophysics and microbiology to understand inequalities of UTIs treatment and replicate them in vitro to help choose the correct antibiotic.
Pls share, home students only #AMR #MicroSky
tinyurl.com/45d8h54u
The project is VERY interdisciplinary, combing social science, biophysics and microbiology to understand inequalities of UTIs treatment and replicate them in vitro to help choose the correct antibiotic.
Pls share, home students only #AMR #MicroSky
tinyurl.com/45d8h54u
Health inequalities which impact the treatment of urinary tract infections
Find out about this studentship opportunity on Health inequalities which impact the treatment of urinary tract infections.
tinyurl.com
November 19, 2024 at 2:05 PM
PhD studentship available.
The project is VERY interdisciplinary, combing social science, biophysics and microbiology to understand inequalities of UTIs treatment and replicate them in vitro to help choose the correct antibiotic.
Pls share, home students only #AMR #MicroSky
tinyurl.com/45d8h54u
The project is VERY interdisciplinary, combing social science, biophysics and microbiology to understand inequalities of UTIs treatment and replicate them in vitro to help choose the correct antibiotic.
Pls share, home students only #AMR #MicroSky
tinyurl.com/45d8h54u
Reposted by 🦠Winnie Lee🦠
It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection in @PLOSPathogens
https://t.co/iDY38oiVbJ
Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed
https://t.co/iDY38oiVbJ
Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed
November 20, 2024 at 1:57 PM
It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection in @PLOSPathogens
https://t.co/iDY38oiVbJ
Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed
https://t.co/iDY38oiVbJ
Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed
Reposted by 🦠Winnie Lee🦠
Research, prevention, awareness -
Controlling Microbes to Fight Infections
Controlling Microbes to Fight Infections
🌍 World Antimicrobial Awareness Week! 🦠
Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat.
Be part of the solution: Follow medical advice and help spread awareness!
#WAAW #AMR #GoBlue #OneHealth
youtu.be/_Qy3aTKiVLE
Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat.
Be part of the solution: Follow medical advice and help spread awareness!
#WAAW #AMR #GoBlue #OneHealth
youtu.be/_Qy3aTKiVLE
WAAW 2024 - World Antimicrobial Awareness Week
YouTube video by CMFI - Cluster of Excellence
youtu.be
November 18, 2024 at 6:22 PM
Research, prevention, awareness -
Controlling Microbes to Fight Infections
Controlling Microbes to Fight Infections
Reposted by 🦠Winnie Lee🦠
It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead to persistent infection in @PLOSPathogens
dx.plos.org/10.1371/jour...
Thanks Gemma Langridge, UKHSA's, Marie Chattaway
& Amina Ismail Ahmed & Winnie Lee
Now to the next 3 papers..
dx.plos.org/10.1371/jour...
Thanks Gemma Langridge, UKHSA's, Marie Chattaway
& Amina Ismail Ahmed & Winnie Lee
Now to the next 3 papers..
From acute to persistent infection: revealing phylogenomic variations in Salmonella Agona
Author summary The persistence of non-typhoidal Salmonella following acute gastroenteritis is a significant challenge for public health but the causes that lead to such chronic infections are understu...
dx.plos.org
November 19, 2024 at 9:47 AM
It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead to persistent infection in @PLOSPathogens
dx.plos.org/10.1371/jour...
Thanks Gemma Langridge, UKHSA's, Marie Chattaway
& Amina Ismail Ahmed & Winnie Lee
Now to the next 3 papers..
dx.plos.org/10.1371/jour...
Thanks Gemma Langridge, UKHSA's, Marie Chattaway
& Amina Ismail Ahmed & Winnie Lee
Now to the next 3 papers..
Reposted by 🦠Winnie Lee🦠
Your regular reminder about editorial standards at Frontiers.
February 15, 2024 at 6:09 PM
Your regular reminder about editorial standards at Frontiers.
Reposted by 🦠Winnie Lee🦠
🌍 World Antimicrobial Awareness Week! 🦠
Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat.
Be part of the solution: Follow medical advice and help spread awareness!
#WAAW #AMR #GoBlue #OneHealth
youtu.be/_Qy3aTKiVLE
Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat.
Be part of the solution: Follow medical advice and help spread awareness!
#WAAW #AMR #GoBlue #OneHealth
youtu.be/_Qy3aTKiVLE
WAAW 2024 - World Antimicrobial Awareness Week
YouTube video by CMFI - Cluster of Excellence
youtu.be
November 18, 2024 at 10:19 AM
🌍 World Antimicrobial Awareness Week! 🦠
Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat.
Be part of the solution: Follow medical advice and help spread awareness!
#WAAW #AMR #GoBlue #OneHealth
youtu.be/_Qy3aTKiVLE
Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat.
Be part of the solution: Follow medical advice and help spread awareness!
#WAAW #AMR #GoBlue #OneHealth
youtu.be/_Qy3aTKiVLE