Tom Driedonks
@tomdriedonks.bsky.social
Postdoctoral Researcher | UMCUtrecht 🇳🇱
Investigating therapeutic uses of extracellular vesicles | ISEV Member at Large | ISEV Social Media manager
Investigating therapeutic uses of extracellular vesicles | ISEV Member at Large | ISEV Social Media manager
Reposted by Tom Driedonks
Some travel grants for UKEV if there are any big UK extracellular vesicle fans out there!
🧪
www.ukev.org.uk/early-career...
🧪
www.ukev.org.uk/early-career...
Early Career Researcher Travel Grants for UKEV Forum 2025 - UK Society for Extracellular Vesicles
Early-career research travel grants for UKEV Forum 2025 UKEV Travel Grants are available to help early career researchers (the applicants) attend and present their research at the UKEV Forum (15th to ...
www.ukev.org.uk
October 13, 2025 at 7:37 AM
Some travel grants for UKEV if there are any big UK extracellular vesicle fans out there!
🧪
www.ukev.org.uk/early-career...
🧪
www.ukev.org.uk/early-career...
Happy to have contributed to this perspectives article about interactions between therapeutic EVs and circulating B cells.
Unexpected discovery, confirmed in different experimental settings. Curious to learn more about these interactions and their therapeutic potential
pubs.acs.org/doi/10.1021/...
Unexpected discovery, confirmed in different experimental settings. Curious to learn more about these interactions and their therapeutic potential
pubs.acs.org/doi/10.1021/...
Extracellular Vesicles and B Cell Interactions: B-Side Track or Greatest Hit?
Substantial efforts have been made in understanding interactions between extracellular vesicles and cells, particularly in small animal models, such as rats and mice. However, many questions remain un...
pubs.acs.org
October 11, 2025 at 6:18 AM
Happy to have contributed to this perspectives article about interactions between therapeutic EVs and circulating B cells.
Unexpected discovery, confirmed in different experimental settings. Curious to learn more about these interactions and their therapeutic potential
pubs.acs.org/doi/10.1021/...
Unexpected discovery, confirmed in different experimental settings. Curious to learn more about these interactions and their therapeutic potential
pubs.acs.org/doi/10.1021/...
October 8, 2025 at 11:11 AM
Had a 14h shift in the lab yesterday. Mice experiment followed by magnetic sorting of different cell types from tissues. Too many washing steps but there were some cells left in the end. Next step is to see whether my EVs have reached their destination 😅
October 3, 2025 at 11:09 AM
Had a 14h shift in the lab yesterday. Mice experiment followed by magnetic sorting of different cell types from tissues. Too many washing steps but there were some cells left in the end. Next step is to see whether my EVs have reached their destination 😅
Yes! Mention of #extracellularvesicles in a @kurzgesagt.org popular science video about pregnancy. Wait until they learn about all the processes EVs play a role in 🤓
September 23, 2025 at 8:28 PM
Yes! Mention of #extracellularvesicles in a @kurzgesagt.org popular science video about pregnancy. Wait until they learn about all the processes EVs play a role in 🤓
Reposted by Tom Driedonks
With @amyhbuck we wrote this piece on extracellular RNAs that intends not to give answers but to propose questions that can expand the field in new directions.
Hope you like it! We really enjoyed a lot brainstorming it.
journals.asm.org/doi/10.1128/...
Hope you like it! We really enjoyed a lot brainstorming it.
journals.asm.org/doi/10.1128/...
mGem: Guides or triggers? Extracellular RNAs beyond vesicular miRNAs | mBio
Blood and other extracellular biofluids have a high RNase content. Hence, from its
origins, the exRNA field has focused on extracellular vesicles (EVs) as the main carriers
of RNA molecules that move ...
journals.asm.org
September 17, 2025 at 3:38 AM
With @amyhbuck we wrote this piece on extracellular RNAs that intends not to give answers but to propose questions that can expand the field in new directions.
Hope you like it! We really enjoyed a lot brainstorming it.
journals.asm.org/doi/10.1128/...
Hope you like it! We really enjoyed a lot brainstorming it.
journals.asm.org/doi/10.1128/...
Reposted by Tom Driedonks
😎 You can already submit your abstracts for #ISEV2026, in Puerto Rico!
🌴 Submit before 13th January 2026, there will be NO late breaking submission
www.abstractscorecard.com/cfp/submit/l...
🌴 Submit before 13th January 2026, there will be NO late breaking submission
www.abstractscorecard.com/cfp/submit/l...
August 26, 2025 at 11:08 AM
😎 You can already submit your abstracts for #ISEV2026, in Puerto Rico!
🌴 Submit before 13th January 2026, there will be NO late breaking submission
www.abstractscorecard.com/cfp/submit/l...
🌴 Submit before 13th January 2026, there will be NO late breaking submission
www.abstractscorecard.com/cfp/submit/l...
Reposted by Tom Driedonks
🎼 Did you know all #ISEV2025 Education Day Talks are on our YouTube channel?
🤩 Check out our playlist: youtu.be/ovtLcTMeyQU?...
🤩 Check out our playlist: youtu.be/ovtLcTMeyQU?...
Education Day 2025 Part 1: EVs. What are they? Where are they from? Where do they go?
YouTube video by EVClub: Extracellular Vesicle Club
youtu.be
August 19, 2025 at 1:42 PM
🎼 Did you know all #ISEV2025 Education Day Talks are on our YouTube channel?
🤩 Check out our playlist: youtu.be/ovtLcTMeyQU?...
🤩 Check out our playlist: youtu.be/ovtLcTMeyQU?...
Reposted by Tom Driedonks
do you ever stare at the ceiling and think about how the worldwide scientific establishment did the impossible and created a COVID vaccine in under a year and the response of the general public has been to go on an unstoppable rampage to destroy science and scientists
July 20, 2025 at 6:46 PM
do you ever stare at the ceiling and think about how the worldwide scientific establishment did the impossible and created a COVID vaccine in under a year and the response of the general public has been to go on an unstoppable rampage to destroy science and scientists
Reposted by Tom Driedonks
📢Call for papers!📢 #JExBio is pleased to announce its first Special Issue 'The Biomolecular Corona of Extracellular Vesicles'. Guest Edited by Professors Massimo Bottini, Benedetta Bussolati, and Annalisa Radeghieri. isevjournals.onlinelibrary.wiley.com/hub/journal/...
July 4, 2025 at 8:57 AM
📢Call for papers!📢 #JExBio is pleased to announce its first Special Issue 'The Biomolecular Corona of Extracellular Vesicles'. Guest Edited by Professors Massimo Bottini, Benedetta Bussolati, and Annalisa Radeghieri. isevjournals.onlinelibrary.wiley.com/hub/journal/...
Reposted by Tom Driedonks
If you haven’t already, please consider signing & sharing this! NIH public servants defending the integrity of our publicly funded health research need our voices. This administration is
“damaging the hard-earned trust between the NIH, academia, & the public that is essential for long-term progress”
“damaging the hard-earned trust between the NIH, academia, & the public that is essential for long-term progress”
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
actionnetwork.org
June 10, 2025 at 1:22 PM
If you haven’t already, please consider signing & sharing this! NIH public servants defending the integrity of our publicly funded health research need our voices. This administration is
“damaging the hard-earned trust between the NIH, academia, & the public that is essential for long-term progress”
“damaging the hard-earned trust between the NIH, academia, & the public that is essential for long-term progress”
Reposted by Tom Driedonks
🚨 EV Fundamental Biology Series: The 'dark matter' RNA of Extracellular Vesicles
This June 12th, join us for a relevant talk on the vesicular RNA topic!
This June 12th, join us for a relevant talk on the vesicular RNA topic!
June 5, 2025 at 2:31 AM
🚨 EV Fundamental Biology Series: The 'dark matter' RNA of Extracellular Vesicles
This June 12th, join us for a relevant talk on the vesicular RNA topic!
This June 12th, join us for a relevant talk on the vesicular RNA topic!
Reposted by Tom Driedonks
Happy to have contributed to this paper by @olivier-de-jong.bsky.social!
A proper balance of loading versus unloading of Cas9 RNPs is needed for effective gene editing ⚖️
pubmed.ncbi.nlm.nih.gov/40393529/
Congratulations to all co-authors!
A proper balance of loading versus unloading of Cas9 RNPs is needed for effective gene editing ⚖️
pubmed.ncbi.nlm.nih.gov/40393529/
Congratulations to all co-authors!
Modulating binding affinity of aptamer-based loading constructs enhances extracellular vesicle-mediated CRISPR/Cas9 delivery - PubMed
The CRISPR/Cas9 toolbox consists of modular nucleases that can be employed to efficiently modify genomic sequences with high specificity. However, delivery of the large Cas9-sgRNA ribonucleoprotein (R...
pubmed.ncbi.nlm.nih.gov
June 4, 2025 at 6:48 AM
Happy to have contributed to this paper by @olivier-de-jong.bsky.social!
A proper balance of loading versus unloading of Cas9 RNPs is needed for effective gene editing ⚖️
pubmed.ncbi.nlm.nih.gov/40393529/
Congratulations to all co-authors!
A proper balance of loading versus unloading of Cas9 RNPs is needed for effective gene editing ⚖️
pubmed.ncbi.nlm.nih.gov/40393529/
Congratulations to all co-authors!
Reposted by Tom Driedonks
📢 Come be a part of the SNEV team!
We’ve got 3 exciting positions open:
1️⃣ Media Team (1 position)
2️⃣ Podcast Team (2 positions)
🗓️ Deadline to apply: May 31st
⏳ Don’t miss your chance to make an impact. Apply NOW!
📩 Link in the Linktr.ee in our bio
We’ve got 3 exciting positions open:
1️⃣ Media Team (1 position)
2️⃣ Podcast Team (2 positions)
🗓️ Deadline to apply: May 31st
⏳ Don’t miss your chance to make an impact. Apply NOW!
📩 Link in the Linktr.ee in our bio
May 21, 2025 at 2:23 PM
📢 Come be a part of the SNEV team!
We’ve got 3 exciting positions open:
1️⃣ Media Team (1 position)
2️⃣ Podcast Team (2 positions)
🗓️ Deadline to apply: May 31st
⏳ Don’t miss your chance to make an impact. Apply NOW!
📩 Link in the Linktr.ee in our bio
We’ve got 3 exciting positions open:
1️⃣ Media Team (1 position)
2️⃣ Podcast Team (2 positions)
🗓️ Deadline to apply: May 31st
⏳ Don’t miss your chance to make an impact. Apply NOW!
📩 Link in the Linktr.ee in our bio
I deep fried two of my SDS PAGE gels today but my most important samples were on gel nr 3 so things are going quite well today 🫠
May 21, 2025 at 1:58 PM
I deep fried two of my SDS PAGE gels today but my most important samples were on gel nr 3 so things are going quite well today 🫠
Personalized gene editing! What a time to be alive
“KJ’s treatment — which built on decades of federally funded research — offers a new path for companies to develop personalized treatments without going through years of expensive development… [this method] eventually could also be used for more common genetic disorders like sickle cell disease”
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
www.nytimes.com
May 16, 2025 at 8:57 AM
Personalized gene editing! What a time to be alive
Pretty cool study showing the effect of acid sphingomyelinase on non-coding RNA cargo of MCF-7 EVs.
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Inhibition of acid or neutral sphingomyelinases differentially impacts RNA and protein cargo sorting to extracellular vesicles
Extracellular vesicles (EVs) form through regulated biogenesis processes involving sphingomyelinases (SMases), enzymes that metabolize sphingomyelin t…
www.sciencedirect.com
May 15, 2025 at 12:52 PM
Pretty cool study showing the effect of acid sphingomyelinase on non-coding RNA cargo of MCF-7 EVs.
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Great that Europe provides opportunities for US researchers. Could strengthen Europe's position as scientific stronghold.
I hope this does not go against opportunities of European researchers. Grant money is competitive enough already, and anti science policies are on the rise here, too 😕
I hope this does not go against opportunities of European researchers. Grant money is competitive enough already, and anti science policies are on the rise here, too 😕
Europe’s choice is clear.
To put science at the heart of its economy.
To become the home of scientific freedom and collaboration.
And to welcome talent from all over the world.
I’m glad to present the first elements of our Choose Europe Initiative.
→ europa.eu/!TTbWbJ
To put science at the heart of its economy.
To become the home of scientific freedom and collaboration.
And to welcome talent from all over the world.
I’m glad to present the first elements of our Choose Europe Initiative.
→ europa.eu/!TTbWbJ
May 6, 2025 at 2:41 PM
Great that Europe provides opportunities for US researchers. Could strengthen Europe's position as scientific stronghold.
I hope this does not go against opportunities of European researchers. Grant money is competitive enough already, and anti science policies are on the rise here, too 😕
I hope this does not go against opportunities of European researchers. Grant money is competitive enough already, and anti science policies are on the rise here, too 😕
NLSEV is well-represented at #ISEV2025 !
@esthernoltethoen.bsky.social @lorenowiczaims.bsky.social @cscheepbouwer.bsky.social @olivier-de-jong.bsky.social
@esthernoltethoen.bsky.social @lorenowiczaims.bsky.social @cscheepbouwer.bsky.social @olivier-de-jong.bsky.social
April 27, 2025 at 7:23 AM
NLSEV is well-represented at #ISEV2025 !
@esthernoltethoen.bsky.social @lorenowiczaims.bsky.social @cscheepbouwer.bsky.social @olivier-de-jong.bsky.social
@esthernoltethoen.bsky.social @lorenowiczaims.bsky.social @cscheepbouwer.bsky.social @olivier-de-jong.bsky.social
Reposted by Tom Driedonks
Climate researchers collaborated with the trip-hop band Massive Attack to reduce the climate impact of live music
https://go.nature.com/4hXzB0Y
https://go.nature.com/4hXzB0Y
How a scientist–pop industry partnership slashed a live gig’s carbon emissions by 98%
Climate researchers collaborated with the trip-hop band Massive Attack to reduce the climate impact of live music.
go.nature.com
March 26, 2025 at 11:35 AM
Climate researchers collaborated with the trip-hop band Massive Attack to reduce the climate impact of live music
https://go.nature.com/4hXzB0Y
https://go.nature.com/4hXzB0Y
From 4L to 15mL, getting somewhere!
#extracellularvesicles
#extracellularvesicles
March 14, 2025 at 2:31 PM
From 4L to 15mL, getting somewhere!
#extracellularvesicles
#extracellularvesicles
Big EV production this week!
Thanks Bart Boogaard, new PhD student in our team and technician Annet van Wesel for great help 💪
Labwork is better together 🧫
(that's just 1 our of 2 full incubators 😎)
Thanks Bart Boogaard, new PhD student in our team and technician Annet van Wesel for great help 💪
Labwork is better together 🧫
(that's just 1 our of 2 full incubators 😎)
March 13, 2025 at 3:12 PM
Big EV production this week!
Thanks Bart Boogaard, new PhD student in our team and technician Annet van Wesel for great help 💪
Labwork is better together 🧫
(that's just 1 our of 2 full incubators 😎)
Thanks Bart Boogaard, new PhD student in our team and technician Annet van Wesel for great help 💪
Labwork is better together 🧫
(that's just 1 our of 2 full incubators 😎)
Reposted by Tom Driedonks
❓ Have you registered already for #ISEV2025?
🐤 Don't wait, early bird discount rates last until March 7th!
buff.ly/3CyMjEE
🐤 Don't wait, early bird discount rates last until March 7th!
buff.ly/3CyMjEE
February 28, 2025 at 11:34 AM
❓ Have you registered already for #ISEV2025?
🐤 Don't wait, early bird discount rates last until March 7th!
buff.ly/3CyMjEE
🐤 Don't wait, early bird discount rates last until March 7th!
buff.ly/3CyMjEE