Syed Mian
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syedmian.bsky.social
Syed Mian
@syedmian.bsky.social
350 followers 420 following 55 posts
Research fellow @crick.ac.uk #BonemarrowStemCells🩸
#MDS #Cancer
#DiseaseModelling #EnvironmentalMinglingMatters #CureForMDS
ASH-EHA TRTH2025
Opinions are my own!

https://scholar.google.com/citations?user=96tYyXUAAAAJ&hl=en
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syedmian.bsky.social
Syed Mian @syedmian.bsky.social · May 1
Excited to share our perspective just out in @leukemia journal! What is bone marrow niche doing in shaping clonal dynamics in MDS and Leukemias.

www.nature.com/articles/s41...
Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis? - Leukemia
Leukemia - Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis?
www.nature.com
Reposted by Syed Mian
lscn.bsky.social
🚨🔥LSCN's "Breaking Barriers in Cell Biology Workflows" is on Wed 19th Nov.

Learn groundbreaking discoveries and the newest cutting-edge technology !👇

🔗https://www.eventbrite.co.uk/e/lscn-workshop-breaking-barriers-in-cell-biology-workflows-tickets-1600912605699?aff=oddtdtcreator
November 17, 2025 at 11:16 AM
Reposted by Syed Mian
crick.ac.uk
We welcome anyone interested in HIV research to join our free annual event marking World AIDS Day.

We’ll hear from expert speakers including Julie Fox, Kevin McKenna and Robin Shattock as they discuss HIV research, clinical trials, policy and activism.

www.eventbrite.co.uk/e/world-aids...
World AIDS Day 2025: Living with HIV
Join us Tue 2 Dec for World AIDS Day. A warm welcome to all — public, researchers, clinicians & anyone curious about HIV/AIDS & science.
www.eventbrite.co.uk
November 13, 2025 at 9:35 AM
Reposted by Syed Mian
crick.ac.uk
Why is it so difficult to understand and treat the diseases that cause dementia?

Join our expert panellists as they answer audience questions about Alzheimer's disease, dementia and the ageing brain.

Listen now on your favourite podcast platform: lnk.to/AQOSDementiaBB
Promotional image for 'Can We Repair the Ageing Brain?' with five speakers and microphones.
November 12, 2025 at 2:38 PM
Reposted by Syed Mian
nature.com
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers

go.nature.com/4hNDvuN
Pressure to publish is rising as research time shrinks, finds survey of scientists
Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.
go.nature.com
November 7, 2025 at 12:33 PM
Reposted by Syed Mian
crick.ac.uk
Just a few weeks left to apply for our clinical PhD programme.

We're looking for clinicians who are passionate about research to join the 3-year fully funded programme.

Learn more and see what positions are available ⬇️

www.crick.ac.uk/careers-and-...
Doctoral clinical fellows
The Crick's clinical PhD programme.
www.crick.ac.uk
October 30, 2025 at 9:41 AM
Reposted by Syed Mian
crick.ac.uk
We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺

Apply by 14 November 2025. 👇

www.crick.ac.uk/careers-stud...
Doctoral clinical fellows
The Crick's clinical PhD programme.
www.crick.ac.uk
October 1, 2025 at 8:37 AM
syedmian.bsky.social
We all must take the responsibility and don’t just complaint about these problems. Take action and don’t be a spectator!
September 29, 2025 at 3:02 PM
Reposted by Syed Mian
crick.ac.uk
Book now for our next #MedicineAtTheCrick event, where researchers and clinicians will explore new insights and breakthroughs in autoimmunity.

🎤 Hosted by @dr-james-lee.bsky.social and @carovinuesa.bsky.social
📅 Thursday 20 November

www.eventbrite.co.uk/e/medicine-a...
Medicine at the Crick
New insights and breakthroughs in autoimmunity
www.eventbrite.co.uk
September 22, 2025 at 10:22 AM
Reposted by Syed Mian
crick.ac.uk
Researchers at the Crick and @kingscollegelondon.bsky.social have discovered that our epithelial cells, which form protective barriers around our organs, use electricity as a way to maintain these protective layers and prevent overcrowding.

www.crick.ac.uk/news/2025-09...
The weakest link: how cells use electricity to eliminate their neighbours to maintain healthy barriers
Researchers at the Francis Crick Institute and King’s College London have uncovered a surprising role for electricity in keeping our body’s protective cell layers healthy, which could potentially prot...
www.crick.ac.uk
September 11, 2025 at 1:39 PM
Reposted by Syed Mian
crick.ac.uk
Edith Heard our new CEO shares ten lessons from her life in science, from curiosity, courage and coffee to the secrets of our genetic code.

www.crick.ac.uk/news/2025-09...
Edith Heard life lessons
Edith Heard, the Crick’s new Director and CEO, shares ten lessons from a life in science, spanning curiosity, courage, coffee, and the secrets of our genetic code.
www.crick.ac.uk
September 10, 2025 at 1:32 PM
Reposted by Syed Mian
elisabethbik.bsky.social
Preprint claiming link between COVID-19 mRNA vaccines and 'transcriptomic dysregulation'/cancer (based on just 10 people who got cancer in the year after vaccination) has been withdrawn.

HT: @reeserichardson.bsky.social

preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
Screenshot from https://www.preprints.org/manuscript/202507.2155/v1 showing the title of the paper with the word Withdrawn marked in red. Full text visible in the screenshot: "This preprint has been withdrawn Preprint - Article - This version is not peer-reviewed. Withdrawn: Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination Natalia von Ranke,Wei Zhang,Philipp Anokin,Nicolas Hulscher,Kevin J. McKernan,Peter A. McCullough,John A. Catanzaro * Withdrawal Statement This preprint has unresolved ethical issues."
September 11, 2025 at 5:50 PM
Reposted by Syed Mian
lizszabo.bsky.social
Vaccines don't cause autism. What does? Mostly genes.
The number of people diagnosed with autism as screening has improved and the definition of autism has been expanded.
www.nbcnews.com/health/healt...
Vaccines don't cause autism. What does?
Scientists say most brain changes that contribute to autistic traits occur before birth.
www.nbcnews.com
September 5, 2025 at 8:31 PM
syedmian.bsky.social
Humanized MPN xenograft model that offers valuable insights into how human BM MSCs interact with JAK2V617F mutant clone.

onlinelibrary.wiley.com/doi/10.1002/... @hemasphere-journal.bsky.social
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo
Myeloproliferative Neoplasms (MPN) are malignancies of hematopoietic stem and progenitor cells (HSPCs) that lead to the overproduction of mature blood cells. These disorders include Essential Thrombo....
onlinelibrary.wiley.com
August 23, 2025 at 11:53 AM
Reposted by Syed Mian
eileen-furlong.bsky.social
Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Team Leader – Genomics Core Facility and Method Development
Are you ready to lead a cutting-edge Genomics Core facility while developing state of the art genomics methods? Join us at EMBL! We are seeking talented scientists to develop and lead a cutting-edge G...
embl.wd103.myworkdayjobs.com
August 11, 2025 at 9:54 AM
Reposted by Syed Mian
charles-debock.bsky.social
So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.
HemaSphere Podcast
Medicine Podcast · Updated Monthly · HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinic...
podcasts.apple.com
August 1, 2025 at 5:01 AM
syedmian.bsky.social
I wonder if this will work for lab based scientific research www.nature.com/articles/d41...
Biggest trial of four-day work week finds workers are happier and feel just as productive
Compressing five days of work into four can create stress, but the benefits outweigh the downsides, sprawling study shows.
www.nature.com
July 22, 2025 at 8:52 AM
Reposted by Syed Mian
crick.ac.uk
Our free exhibition showcasing the top 25 entries of this year’s Wellcome Photography Prize is now open.

See the winning images and learn more about the exhibition itself, open Wednesday-Saturday until 18 October.

www.crick.ac.uk/news/2025-07...
Wellcome Photography Prize exhibition opens at the Crick
The Wellcome Photography Prize exhibition opens today at the Francis Crick Institute.
www.crick.ac.uk
July 17, 2025 at 2:15 PM
Reposted by Syed Mian
alejofraticelli.bsky.social
If you want to know about Blood Stem Cell Aging, then THIS is the meeting to go to.
I will be presenting the latest results of the Fraticelli Lab regarding HSC memories and clonal dynamics.

JOIN US !!!!!

ehaweb.org/connect-netw...
July 11, 2025 at 8:43 AM
syedmian.bsky.social
www.nature.com/articles/s41...
A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression - Nature Communications
In Myeloiddysplastic syndromes, CEBPA mutations are linked to disease progression and AML. Here, the authors use somatic reprogramming and genome editing to generate isogenic cell lines from an MDS pa...
www.nature.com
July 2, 2025 at 7:11 AM
syedmian.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Fetal‐hemoglobin‐expressing red blood cells (“F cells”) consist of three distinct types as revealed by single‐cell transcriptomic analysis of circulating reticulocytes
Click on the article title to read more.
onlinelibrary.wiley.com
June 30, 2025 at 6:36 PM
Reposted by Syed Mian
crick.ac.uk
We’re looking forward to welcoming families to Discovery Day tomorrow 🎉

It’s going to be a hot and sunny day, so please come prepared with hats, sun cream and water.

Visit the webpage for more information about the day ⬇️
🔗 www.crick.ac.uk/whats-on/dis...
A large group of adults and children are engaging in various activities, including some using hula hoops, outside a large building in the sun.
June 20, 2025 at 10:46 AM
Reposted by Syed Mian
jancools.bsky.social
Exciting to share the new impact factor of @hemasphere-journal.bsky.social, the #openaccess journal of the European Hematology Association (EHA).
The 2024 Journal Impact Factor is 14.6 - ranking as number 5 of 99 hematology journals (Source: Journal Citations Reports, Clarivate).
June 18, 2025 at 6:07 AM
Reposted by Syed Mian
marcusbuschbeck.bsky.social
It is a great honor and greater responsibility to take over the chair of the #EHA research committee from Brian Huntly and Ruud Delwel.

Together with Dominique Bonnet I will lead the committee dealing with all aspects of research at #EHA.
June 15, 2025 at 5:00 AM
Reposted by Syed Mian
crick.ac.uk
Don’t miss our next free #MedicineAtTheCrick event, happening Thursday 19 June.

We’ve assembled a full programme of expert speakers and panellists to explore the importance of pigmentation in health and disease.

For more information or to book ⬇️
www.eventbrite.co.uk/e/medicine-a...
Medicine at the Crick | Pigmentation in health and disease
Our Medicine at the Crick event series showcases major advances in biomedical science.
www.eventbrite.co.uk
June 13, 2025 at 1:41 PM
Reposted by Syed Mian
crick.ac.uk
The deadline for early bird registration for the 5th Crick Cancer Conference has been extended.

See the full programme and book by 15 July to take advantage of reduced ticket rates for early bookers ⤵️ www.crick.ac.uk/whats-on/5th...
5th Crick International Cancer Conference
www.crick.ac.uk
June 3, 2025 at 4:36 PM