Syed Mian
@syedmian.bsky.social
Research fellow @crick.ac.uk #BonemarrowStemCells🩸
#MDS #Cancer
#DiseaseModelling #EnvironmentalMinglingMatters #CureForMDS
ASH-EHA TRTH2025
Opinions are my own!
https://scholar.google.com/citations?user=96tYyXUAAAAJ&hl=en
#MDS #Cancer
#DiseaseModelling #EnvironmentalMinglingMatters #CureForMDS
ASH-EHA TRTH2025
Opinions are my own!
https://scholar.google.com/citations?user=96tYyXUAAAAJ&hl=en
Pinned
Syed Mian
@syedmian.bsky.social
· May 1
Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis? - Leukemia
Leukemia - Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis?
www.nature.com
Excited to share our perspective just out in @leukemia journal! What is bone marrow niche doing in shaping clonal dynamics in MDS and Leukemias.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Syed Mian
Abstract submission just opened for #ISEH2026 in Frankfurt. Outstanding scientific program; welcoming community; and more than double the number of short talk slots for abstract to be presented in. Looking forward to seeing you there. @isehsociety.bsky.social
Submit an abstract by 2 April for opportunities to present your work at #ISEH2026 🏙️! With over 45 short talk slots, don't miss this opportunity to share your findings with the international scientific community. Learn more: iseh.org/Annual-Meeti...
February 6, 2026 at 7:29 AM
Abstract submission just opened for #ISEH2026 in Frankfurt. Outstanding scientific program; welcoming community; and more than double the number of short talk slots for abstract to be presented in. Looking forward to seeing you there. @isehsociety.bsky.social
Reposted by Syed Mian
Hi Bluesky, we're Blood Cancer UK 👋
We're dedicated to beating blood cancer through research, and supporting everyone affected by leukaemia, lymphoma, myeloma, MDS & MPNs.
We're just dipping our toe in to see how we like it here...
Let us know if you'd like us to stick around 👀
We're dedicated to beating blood cancer through research, and supporting everyone affected by leukaemia, lymphoma, myeloma, MDS & MPNs.
We're just dipping our toe in to see how we like it here...
Let us know if you'd like us to stick around 👀
February 3, 2026 at 3:08 PM
Hi Bluesky, we're Blood Cancer UK 👋
We're dedicated to beating blood cancer through research, and supporting everyone affected by leukaemia, lymphoma, myeloma, MDS & MPNs.
We're just dipping our toe in to see how we like it here...
Let us know if you'd like us to stick around 👀
We're dedicated to beating blood cancer through research, and supporting everyone affected by leukaemia, lymphoma, myeloma, MDS & MPNs.
We're just dipping our toe in to see how we like it here...
Let us know if you'd like us to stick around 👀
Reposted by Syed Mian
Happy to share our latest work on the epigenetic basis of trained immunity in hematopoietic stem cells! @bcmhouston.bsky.social @texaschildrens.bsky.social
For decades, memory-like responses in immune cells have remained unexplained
@thekinglab.bsky.social & team reveal epigenetic changes in hematopoietic stem & progenitor cells in a mycobacterial infection model that are retained in downstream macrophages: doi.org/10.1172/jci....
@thekinglab.bsky.social & team reveal epigenetic changes in hematopoietic stem & progenitor cells in a mycobacterial infection model that are retained in downstream macrophages: doi.org/10.1172/jci....
January 29, 2026 at 1:35 PM
Happy to share our latest work on the epigenetic basis of trained immunity in hematopoietic stem cells! @bcmhouston.bsky.social @texaschildrens.bsky.social
Reposted by Syed Mian
Book your free tickets now for our next #MedicineAtTheCrick event on Thursday 12 March, hosted by @andreas-t-schaefer.bsky.social, where researchers and clinicians will explore ‘neurotechnologies’ that help us better understand and decode the brain.
www.eventbrite.co.uk/e/medicine-a...
www.eventbrite.co.uk/e/medicine-a...
Medicine at the Crick| Interfacing the human brain: neurons to networks
Hybrid event taking place virtually and in person, organised by The Francis Crick Institute, London
www.eventbrite.co.uk
January 26, 2026 at 11:33 AM
Book your free tickets now for our next #MedicineAtTheCrick event on Thursday 12 March, hosted by @andreas-t-schaefer.bsky.social, where researchers and clinicians will explore ‘neurotechnologies’ that help us better understand and decode the brain.
www.eventbrite.co.uk/e/medicine-a...
www.eventbrite.co.uk/e/medicine-a...
Reposted by Syed Mian
Applications to our 2026 Summer Student Training Programme are now open.
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
Summer students
Our nine-week summer training programme provides undergraduates with hands-on experience of working in a research lab.
www.crick.ac.uk
January 8, 2026 at 9:39 AM
Applications to our 2026 Summer Student Training Programme are now open.
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
Reposted by Syed Mian
“We need to take on the defence of science for the world.”
In a wide-ranging and frank conversation, Paul Nurse reflects on his years leading the Francis Crick Institute with our new director, Edith Heard.
www.crick.ac.uk/news/2025-12...
In a wide-ranging and frank conversation, Paul Nurse reflects on his years leading the Francis Crick Institute with our new director, Edith Heard.
www.crick.ac.uk/news/2025-12...
Paul Nurse in conversation with Edith Heard
Standing up for science, the art of leadership and cups of tea with the Prime Minister - Paul Nurse reflects on his years as CEO of the Francis Crick Institute with new director Edith Heard.
www.crick.ac.uk
December 17, 2025 at 10:13 AM
“We need to take on the defence of science for the world.”
In a wide-ranging and frank conversation, Paul Nurse reflects on his years leading the Francis Crick Institute with our new director, Edith Heard.
www.crick.ac.uk/news/2025-12...
In a wide-ranging and frank conversation, Paul Nurse reflects on his years leading the Francis Crick Institute with our new director, Edith Heard.
www.crick.ac.uk/news/2025-12...
Reposted by Syed Mian
TODAY at #ASH2025 New Frontiers in Neutrophil Biology. W311 at 4pm. Ostuni, Bonnet, Findlay. See you there!! @welner.bsky.social @leegrimeslab.bsky.social
December 6, 2025 at 1:02 PM
TODAY at #ASH2025 New Frontiers in Neutrophil Biology. W311 at 4pm. Ostuni, Bonnet, Findlay. See you there!! @welner.bsky.social @leegrimeslab.bsky.social
Reposted by Syed Mian
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Reposted by Syed Mian
Researchers at the Crick, @psich.bsky.social and @esrf.fr have developed a new way to look deeper into brain cell connections by using a particle accelerator and a kind of resin borrowed from the aerospace industry.
www.crick.ac.uk/news/2025-11...
www.crick.ac.uk/news/2025-11...
From aerospace to neuroscience: new imaging tech captures the brain’s intricate connections
Inspired by technologies used in aerospace engineering, scientists have developed a way to capture the brain’s intricate structures using X-rays without destroying the samples.
www.crick.ac.uk
November 27, 2025 at 12:10 PM
Researchers at the Crick, @psich.bsky.social and @esrf.fr have developed a new way to look deeper into brain cell connections by using a particle accelerator and a kind of resin borrowed from the aerospace industry.
www.crick.ac.uk/news/2025-11...
www.crick.ac.uk/news/2025-11...
Reposted by Syed Mian
The program for the @isehsociety.bsky.social annual meeting in Frankfurt is taking shape. Check out the amazing lineup of speakers who have confirmed so far iseh.org/Annual-Meeti...
Annual Meeting
iseh.org
November 26, 2025 at 7:48 PM
The program for the @isehsociety.bsky.social annual meeting in Frankfurt is taking shape. Check out the amazing lineup of speakers who have confirmed so far iseh.org/Annual-Meeti...
Reposted by Syed Mian
🚨🔥LSCN's "Breaking Barriers in Cell Biology Workflows" is on Wed 19th Nov.
Learn groundbreaking discoveries and the newest cutting-edge technology !👇
🔗https://www.eventbrite.co.uk/e/lscn-workshop-breaking-barriers-in-cell-biology-workflows-tickets-1600912605699?aff=oddtdtcreator
Learn groundbreaking discoveries and the newest cutting-edge technology !👇
🔗https://www.eventbrite.co.uk/e/lscn-workshop-breaking-barriers-in-cell-biology-workflows-tickets-1600912605699?aff=oddtdtcreator
November 17, 2025 at 11:16 AM
🚨🔥LSCN's "Breaking Barriers in Cell Biology Workflows" is on Wed 19th Nov.
Learn groundbreaking discoveries and the newest cutting-edge technology !👇
🔗https://www.eventbrite.co.uk/e/lscn-workshop-breaking-barriers-in-cell-biology-workflows-tickets-1600912605699?aff=oddtdtcreator
Learn groundbreaking discoveries and the newest cutting-edge technology !👇
🔗https://www.eventbrite.co.uk/e/lscn-workshop-breaking-barriers-in-cell-biology-workflows-tickets-1600912605699?aff=oddtdtcreator
Reposted by Syed Mian
We welcome anyone interested in HIV research to join our free annual event marking World AIDS Day.
We’ll hear from expert speakers including Julie Fox, Kevin McKenna and Robin Shattock as they discuss HIV research, clinical trials, policy and activism.
www.eventbrite.co.uk/e/world-aids...
We’ll hear from expert speakers including Julie Fox, Kevin McKenna and Robin Shattock as they discuss HIV research, clinical trials, policy and activism.
www.eventbrite.co.uk/e/world-aids...
World AIDS Day 2025: Living with HIV
Join us Tue 2 Dec for World AIDS Day. A warm welcome to all — public, researchers, clinicians & anyone curious about HIV/AIDS & science.
www.eventbrite.co.uk
November 13, 2025 at 9:35 AM
We welcome anyone interested in HIV research to join our free annual event marking World AIDS Day.
We’ll hear from expert speakers including Julie Fox, Kevin McKenna and Robin Shattock as they discuss HIV research, clinical trials, policy and activism.
www.eventbrite.co.uk/e/world-aids...
We’ll hear from expert speakers including Julie Fox, Kevin McKenna and Robin Shattock as they discuss HIV research, clinical trials, policy and activism.
www.eventbrite.co.uk/e/world-aids...
Reposted by Syed Mian
Why is it so difficult to understand and treat the diseases that cause dementia?
Join our expert panellists as they answer audience questions about Alzheimer's disease, dementia and the ageing brain.
Listen now on your favourite podcast platform: lnk.to/AQOSDementiaBB
Join our expert panellists as they answer audience questions about Alzheimer's disease, dementia and the ageing brain.
Listen now on your favourite podcast platform: lnk.to/AQOSDementiaBB
November 12, 2025 at 2:38 PM
Why is it so difficult to understand and treat the diseases that cause dementia?
Join our expert panellists as they answer audience questions about Alzheimer's disease, dementia and the ageing brain.
Listen now on your favourite podcast platform: lnk.to/AQOSDementiaBB
Join our expert panellists as they answer audience questions about Alzheimer's disease, dementia and the ageing brain.
Listen now on your favourite podcast platform: lnk.to/AQOSDementiaBB
Reposted by Syed Mian
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers
go.nature.com/4hNDvuN
go.nature.com/4hNDvuN
Pressure to publish is rising as research time shrinks, finds survey of scientists
Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.
go.nature.com
November 7, 2025 at 12:33 PM
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers
go.nature.com/4hNDvuN
go.nature.com/4hNDvuN
Reposted by Syed Mian
Just a few weeks left to apply for our clinical PhD programme.
We're looking for clinicians who are passionate about research to join the 3-year fully funded programme.
Learn more and see what positions are available ⬇️
www.crick.ac.uk/careers-and-...
We're looking for clinicians who are passionate about research to join the 3-year fully funded programme.
Learn more and see what positions are available ⬇️
www.crick.ac.uk/careers-and-...
Doctoral clinical fellows
The Crick's clinical PhD programme.
www.crick.ac.uk
October 30, 2025 at 9:41 AM
Just a few weeks left to apply for our clinical PhD programme.
We're looking for clinicians who are passionate about research to join the 3-year fully funded programme.
Learn more and see what positions are available ⬇️
www.crick.ac.uk/careers-and-...
We're looking for clinicians who are passionate about research to join the 3-year fully funded programme.
Learn more and see what positions are available ⬇️
www.crick.ac.uk/careers-and-...
Reposted by Syed Mian
We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Doctoral clinical fellows
The Crick's clinical PhD programme.
www.crick.ac.uk
October 1, 2025 at 8:37 AM
We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
We all must take the responsibility and don’t just complaint about these problems. Take action and don’t be a spectator!
Breaking the cycle of institutional betrayal and the culture of silence requires decisive actions to promote transparency, accountability and supportive environments in both academia and industry go.nature.com/482BUOY
rdcu.be/eIcEI
rdcu.be/eIcEI
Chronic silencing is a critical barrier to breaking the cycle of bullying in academia and industry - Nature Biotechnology
Breaking the cycle of institutional betrayal and the culture of silence requires decisive actions to promote transparency, accountability and supportive environments in both academia and industry.
go.nature.com
September 29, 2025 at 3:02 PM
We all must take the responsibility and don’t just complaint about these problems. Take action and don’t be a spectator!
Reposted by Syed Mian
Book now for our next #MedicineAtTheCrick event, where researchers and clinicians will explore new insights and breakthroughs in autoimmunity.
🎤 Hosted by @dr-james-lee.bsky.social and @carovinuesa.bsky.social
📅 Thursday 20 November
www.eventbrite.co.uk/e/medicine-a...
🎤 Hosted by @dr-james-lee.bsky.social and @carovinuesa.bsky.social
📅 Thursday 20 November
www.eventbrite.co.uk/e/medicine-a...
Medicine at the Crick
New insights and breakthroughs in autoimmunity
www.eventbrite.co.uk
September 22, 2025 at 10:22 AM
Book now for our next #MedicineAtTheCrick event, where researchers and clinicians will explore new insights and breakthroughs in autoimmunity.
🎤 Hosted by @dr-james-lee.bsky.social and @carovinuesa.bsky.social
📅 Thursday 20 November
www.eventbrite.co.uk/e/medicine-a...
🎤 Hosted by @dr-james-lee.bsky.social and @carovinuesa.bsky.social
📅 Thursday 20 November
www.eventbrite.co.uk/e/medicine-a...
Reposted by Syed Mian
Researchers at the Crick and @kingscollegelondon.bsky.social have discovered that our epithelial cells, which form protective barriers around our organs, use electricity as a way to maintain these protective layers and prevent overcrowding.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
The weakest link: how cells use electricity to eliminate their neighbours to maintain healthy barriers
Researchers at the Francis Crick Institute and King’s College London have uncovered a surprising role for electricity in keeping our body’s protective cell layers healthy, which could potentially prot...
www.crick.ac.uk
September 11, 2025 at 1:39 PM
Researchers at the Crick and @kingscollegelondon.bsky.social have discovered that our epithelial cells, which form protective barriers around our organs, use electricity as a way to maintain these protective layers and prevent overcrowding.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
Reposted by Syed Mian
Edith Heard our new CEO shares ten lessons from her life in science, from curiosity, courage and coffee to the secrets of our genetic code.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
Edith Heard life lessons
Edith Heard, the Crick’s new Director and CEO, shares ten lessons from a life in science, spanning curiosity, courage, coffee, and the secrets of our genetic code.
www.crick.ac.uk
September 10, 2025 at 1:32 PM
Edith Heard our new CEO shares ten lessons from her life in science, from curiosity, courage and coffee to the secrets of our genetic code.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
Reposted by Syed Mian
Preprint claiming link between COVID-19 mRNA vaccines and 'transcriptomic dysregulation'/cancer (based on just 10 people who got cancer in the year after vaccination) has been withdrawn.
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
September 11, 2025 at 5:50 PM
Preprint claiming link between COVID-19 mRNA vaccines and 'transcriptomic dysregulation'/cancer (based on just 10 people who got cancer in the year after vaccination) has been withdrawn.
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
HT: @reeserichardson.bsky.social
preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...
Reposted by Syed Mian
Vaccines don't cause autism. What does? Mostly genes.
The number of people diagnosed with autism as screening has improved and the definition of autism has been expanded.
www.nbcnews.com/health/healt...
The number of people diagnosed with autism as screening has improved and the definition of autism has been expanded.
www.nbcnews.com/health/healt...
Vaccines don't cause autism. What does?
Scientists say most brain changes that contribute to autistic traits occur before birth.
www.nbcnews.com
September 5, 2025 at 8:31 PM
Vaccines don't cause autism. What does? Mostly genes.
The number of people diagnosed with autism as screening has improved and the definition of autism has been expanded.
www.nbcnews.com/health/healt...
The number of people diagnosed with autism as screening has improved and the definition of autism has been expanded.
www.nbcnews.com/health/healt...
Humanized MPN xenograft model that offers valuable insights into how human BM MSCs interact with JAK2V617F mutant clone.
onlinelibrary.wiley.com/doi/10.1002/... @hemasphere-journal.bsky.social
onlinelibrary.wiley.com/doi/10.1002/... @hemasphere-journal.bsky.social
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo
Myeloproliferative Neoplasms (MPN) are malignancies of hematopoietic stem and progenitor cells (HSPCs) that lead to the overproduction of mature blood cells. These disorders include Essential Thrombo....
onlinelibrary.wiley.com
August 23, 2025 at 11:53 AM
Humanized MPN xenograft model that offers valuable insights into how human BM MSCs interact with JAK2V617F mutant clone.
onlinelibrary.wiley.com/doi/10.1002/... @hemasphere-journal.bsky.social
onlinelibrary.wiley.com/doi/10.1002/... @hemasphere-journal.bsky.social
Reposted by Syed Mian
Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Team Leader – Genomics Core Facility and Method Development
Are you ready to lead a cutting-edge Genomics Core facility while developing state of the art genomics methods? Join us at EMBL! We are seeking talented scientists to develop and lead a cutting-edge G...
embl.wd103.myworkdayjobs.com
August 11, 2025 at 9:54 AM
Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Syed Mian
So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.
HemaSphere Podcast
Medicine Podcast · Updated Monthly · HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinic...
podcasts.apple.com
August 1, 2025 at 5:01 AM
So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.