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snipperspace.bsky.social
@snipperspace.bsky.social
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spooniethreads.bsky.social
Mount Sinai just published the first clinician’s manual for infection-associated chronic illnesses—including long COVID, ME/CFS, and post-Lyme. This free guide covers everything from diagnosis to infection prevention and patient care.

www.mountsinai.org/about/newsro...
Mount Sinai Creates First Manual for Treating Infection-Associated Chronic Illness for Clinicians
www.mountsinai.org
September 7, 2025 at 6:22 PM
Reposted
plaguepoems.bsky.social
Studies
encompassing 14 nations
reveal a rate of long Covid
between 25% and 30%
but don’t worry
everyone you know
is doing fine,
your coworkers are always sick,
your friends are always tired,
your sibling’s mind is foggy,
but don’t worry
everyone you know
is doing just fine.
April 24, 2025 at 5:09 PM
Reposted
salzmoritz.bsky.social
#MECFS

Das ist eine riesige Menge von kranken und schwerkranken Patient*innen!
Quelle: nationales Referenzzentrum für postvirales Syndrome
1.4. Anwendung und Schätzungen für Österreich Für Österreich ergeben sich daraus folgende Schätzungen: Bevölkerungs- anzahl 2025 Gesamtzahl ME/CFS- Betroffener (0,8% der Bev.) Moderat Betr.: Überwiegend nicht mehr arbeitsfähig (ca. 60%) Schwer und sehr schwer Betr.: haus-/bettgebun- den (ca. 20% ) Österreich 9 198 214 73 586 44 151 14 717 Bgld. 301 819 2 415 1 449 483 Ktn. 570 194 4 562 2 737 912 NÖ 1 727 759 13 822 8 293 2 764 OÖ 1 535 677 12 285 7 371 2 457 Sbg. 572 905 4 583 2 750 917 Stmk. 1 271 940 10 176 6 105 2 035 T 777 773 6 222 3 733 1 244 Vbg. 411 748 3 294 1 976 659 W 2 028 399 16 227 9 736 3 245 Tabelle 2: Anzahl ME/CFS-Betroffener, Bevölkerungsanzahl Stand Jänner 2025
April 24, 2025 at 5:36 PM
Reposted
westernu.ca
Scientists from #WesternU and the Schmidt Initiative for Long Covid (SILC) are leading a new global clinical trial to test existing drugs as potential treatments for long COVID, aiming to help patients around the world. #SchulichMedDent @schmidtinitiative.bsky.social
Global clinical trial to test existing drugs as long COVID treatments
Western and Schmidt Initiative for Long Covid will test two existing drugs as treatments for long COVID in a clinical trial with patients worldwide.
buff.ly
April 24, 2025 at 5:37 PM
Reposted
buonsenso.bsky.social
Long Covid and ME/CFS are immune mediated conditions

danilobuonsenso.substack.com/p/long-covid...
Long Covid and ME/CFS are immune mediated conditions
Some of you know that I usually manage most severe cases of Long Covid and ME/CFS with immunological therapies.
danilobuonsenso.substack.com
April 20, 2025 at 3:37 PM
Reposted
tatianatrifan.bsky.social
"Long Covid is accompanied by a blood protein signature marked by increased complement activation and thromboinflammation, including activated platelets and markers of red blood cell lysis. Tissue injury may also be complement-mediated [...]"

www.science.org/doi/10.1126/...
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid
Analysis of blood revealed that Long COVID is characterized by changes to complement proteins and platelet activation.
www.science.org
February 25, 2025 at 4:45 PM
Reposted
juliadoubleday.bsky.social
Worked hard on this, and I hope it will be a useful resource for many.

A beginner’s guide to Long COVID, with a discussion of mechanisms:

www.thegauntlet.news/p/what-is-lo...
What is Long COVID?
A Beginner's Guide
www.thegauntlet.news
February 7, 2025 at 8:59 PM
Reposted
coresinai.bsky.social
Long COVID and viral reactivation are linked. Our latest trial focuses on repurposing existing, broad spectrum antivirals to reduce symptoms in adults with #LongCOVID. Our clinical trial is currently recruiting!
February 8, 2025 at 1:59 PM
Reposted
coresinai.bsky.social
You’re not alone. We’re here to help you navigate the path to recovery. 🌿 #LongCOVID #TickBorne #VectorBorne #MECFS #ChronicIllness #CoRE #MountSinai #Research
February 7, 2025 at 5:00 PM
Reposted
corbyhart.bsky.social
"The OECD, a club of mostly rich nations, estimates long COVID could be costing its 38 members $864 billion to $1.04 trillion annually due to reductions in quality of life and labour force participation. This does not include the extra burden on health services."
Long COVID costs countries billions of dollars
Long COVID is causing significant economic damage, with estimates suggesting that millions globally face persistent health issues impacting productivity and increasing healthcare costs. Countries like...
economictimes.indiatimes.com
February 7, 2025 at 4:12 PM
Reposted
tomkindlon.bsky.social
From @meresearchuk.bsky.social

Recently we reported on a study suggesting endothelial dysfunction could play a role in orthostatic intolerance in ME/CFS. Read a summary of other ME Research UK articles related to endothelial dysfunction in ME/CFS - bit.ly/3Ej9sv8

#MECFS #myalgicencephalomyelitis
Endothelial dysfunction in ME/CFS The endothelium - a thin layer of cells lining every blood vessel - plays a pivotal role in regulating blood flow, blood clotting, and inflammatory responses. Research suggests that ME/CFS may involve damage to the endothelium leading to endothelial dysfunction (improper functioning of the endothelium). ME/CFS research says: significantly impaired endothelial function in both small and large vessels compared to healthy controls herpesvirus infection, such as Epstein-Barr virus (EBV) and HHV-6, could contribute to damage of endothelium endothelial cells lining blood vessel reduced nitric oxide production in ME/CFS may suggest mechanism of endothelial dysfunction increased microRNAS in ME/CFS indicate endothelial dysfunction endothelial dysfunction may underly orthostatic intolerance in ME/CFS INFORM. INFLUENCE. INVEST. ME RESEARCH UK SC036942
February 3, 2025 at 3:58 PM
Reposted
scotjess.bsky.social
@meresearchuk.bsky.social
Research showing endothelial dysfunction in #MEcfs

www.meresearch.org.uk/endothelial-...
Endothelial dysfunction in ME/CFS – our articles
www.meresearch.org.uk
February 3, 2025 at 2:46 PM
Reposted
topazstudioscom.bsky.social
"Study: #COVID19 linked to #chronic #fatigue illness. A new study being conducted in part by University of Utah Health shows COVID-19 infection is associated with a nearly eightfold increase in myalgic encephalomyelitis/chronic fatigue syndrome."

www.standard.net/news/2025/fe... #MECFS
University of Utah Health study: COVID-19 linked to chronic fatigue illness
A new study being conducted in part by University of Utah Health shows COVID-19 infection is associated with a nearly eightfold increase in myalgic encephalomyelitis/chronic fatigue syndrome. Senior a...
www.standard.net
February 2, 2025 at 7:10 PM
Reposted
bhanlon15.bsky.social
'Nearly 2% of new Swiss disability insurance claims involve Long Covid'

www.swissinfo.ch/eng/life-agi...
Nearly 2% of new Swiss disability insurance claims involve Long Covid
Just under 2% of new claims submitted to the disability insurance between 2021 and 2023 concern people suffering from Long Covid.
www.swissinfo.ch
January 30, 2025 at 6:12 PM
Reposted
bhanlon15.bsky.social
The Daily, Univ. of Washington: “Five years of COVID-19: Jennifer Nemhauser and the path to long COVID diagnosis”

“As of December 2024, 20 million Americans have been diagnosed with long COVID”

www.dailyuw.com/science/five...
Five years of COVID-19: Jennifer Nemhauser and the path to long COVID diagnosis
Editor’s note: January 2025 marks five years since the beginning of the COVID-19 pandemic that resulted in 1,216,305 American deaths and changed how United States society functions today. This four-pa...
www.dailyuw.com
January 29, 2025 at 4:41 PM
Reposted
waldmeer.bsky.social
Wer die somatische Krankheit ME/CFS heute noch als "psychisch" etikettiert, hat den Anschluss an die Wissenschaft verloren und schadet den Betroffenen. Hier eine wachsende Sammlung von lesenswerten Artikeln gegen die Psychologisierung von ME/CFS (und Long Covid):
August 26, 2024 at 4:30 PM
Reposted
waldmeer.bsky.social
Heute veröffentlicht: Die erweiterte und formatierte Fassung dieses wichtigen Artikels von Mark Vink und Alexandra Vink-Niese gegen die Psychologisierung von ME/CFS.

doi.org/10.3389/fnhu...

Zahlreiche weitere Texte zu diesem Themenfeld findet ihr in dem Thread unter diesem Beitrag. 👇
Frontiers | CBT and graded exercise therapy studies have proven that ME/CFS and long COVID are physical diseases, yet no one is aware of that
The cognitive behavioral model (CBmodel) (1,2) has dominated the world of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) since the 1990s. Accord...
doi.org
January 29, 2025 at 2:24 PM
Reposted
merlinoilmago.bsky.social
È stato messo a punto un panel di test ematici valido per identificare non notevole accuratezza li sviluppo del Long COVID nei bambini, ma valido anche per adulti.
longcovidadvoc.com Long Covid Advocacy @longcovidadvoc.com · Jan 25
In Nature - Paediatric Research

🧪Protein analysis of blood vessels

⬆️ proinflammatory and blood vessel inflammation

🥳#LongCovid was able to be identified with an accuracy of 93%

Great to see some decent research for #longcovidkids

Paper 👇
https://buff.ly/3WxYyIk
infographic showing higher expression of the proinflammatory and pro-angiogenetic set of chemokines CXCL11, CXCL1, CXCL5, CXCL6, CXCL8, TNFSF11, OSM, STAMBP1a.
January 25, 2025 at 11:17 AM
Reposted
themaskerscomic.bsky.social
On connecting the dots on #longcovid

www.frontiersin.org/journals/cel...
Frontiers | Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction
www.frontiersin.org
January 23, 2025 at 3:17 PM
Reposted
dlingenfelter.bsky.social
Dysfunction of the cerebral microvasculature can lead to endothelial dysfunction, impaired neurovascular coupling, and blood-brain barrier disruption.

These factors collectively contribute to the neurocognitive impairments observed in Long COVID patients.
link.springer.com/article/10.1...
Cerebromicrovascular Mechanisms Contributing to Long COVID The authors of the article "Cerebromicrovascular mechanisms contributing to long COVID: implications for neurocognitive health" delves into the intricate relationship between long COVID and neurocognitive health. Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection, has emerged as a significant concern for many individuals who have recovered from COVID-19. This condition manifests through a variety of symptoms, including fatigue, brain fog, anosmia, sleep disturbances, and mood disorders. Central to the discussion is the dysfunction of the cerebral microvasculature, which plays a pivotal role in the onset of neurocognitive symptoms associated with long COVID. The cerebral microvasculature comprises the small blood vessels in the brain, and its dysfunction can lead to endothelial dysfunction, impaired neurovascular coupling, and blood-brain barrier disruption. These factors collectively contribute to the neurocognitive impairments observed in long COVID patients. Several mechanisms are at play in this dysfunction. Firstly, the endothelial tropism of SARS-CoV-2, where the virus targets the inner lining of blood vessels, is a significant factor. Additionally, mitochondrial dysfunction leads to oxidative stress and inflammation, further exacerbating the condition. The formation of autoantibodies also plays a role in aggravating neurovascular injury. These mechanisms contribute to chronic conditions such as white matter hyperintensities and amyloid pathology, which may accelerate neurodegenerative processes like Alzheimer's disease. Advanced imaging techniques are crucial for assessing cerebromicrovascular health and guiding targeted interventions. These techniques enable healthcare professionals to identify and address the cerebrovascular complications of long COVID effectively. Age-related risks are also highlighted in the article. Older adults and individuals with pre-existing conditions are …
January 11, 2025 at 6:38 PM
Reposted
marushka-t.bsky.social
A useful ME primer that will leave you with more expertise than the average GP.

410 million people globally have long COVID. Half of people with long COVID also meet the diagnostic criteria for ME. Both disable people. Time for health authorities to stop pretending COVID is no big deal.
January 11, 2025 at 7:24 PM
Reposted
dlingenfelter.bsky.social
Cerebromicrovascular dysfunction, including endothelial dysfunction, plays a central role in Long COVID.

SARS-CoV-2 infects cerebral endothelial cells, leading to mitochondrial dysfunction, oxidative stress, and chronic vascular inflammation.
link.springer.com/article/10.1...
Here's a summary of the main points from the article on cerebromicrovascular mechanisms contributing to long COVID and its implications for neurocognitive health: - **Long COVID**: A condition where symptoms persist beyond the acute phase of SARS-CoV-2 infection, affecting 10%-30% of those infected, with notable neurocognitive symptoms like brain fog. - **Cerebromicrovascular Dysfunction**: Plays a central role in long COVID, including endothelial dysfunction, impaired neurovascular coupling, and blood-brain barrier disruption. - **Key Mechanisms**: - **Endothelial Infection**: SARS-CoV-2 infects cerebral endothelial cells, leading to mitochondrial dysfunction, oxidative stress, and chronic vascular inflammation. - **Neurovascular Injury**: Results in white matter hyperintensities, amyloid pathology, and accelerates neurodegenerative processes. - **Advanced Imaging**: Emphasized for assessing cerebromicrovascular health. - **Targeted Interventions**: Needed to address cerebromicrovascular complications. The article underscores the importance of understanding these mechanisms to develop treatments for mitigating the long-term neurocognitive consequences of long COVID. https://link.springer.com/article/10.1007/s11357-024-01487-4
January 11, 2025 at 7:30 PM