Danilo Buonsenso
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buonsenso.bsky.social
Danilo Buonsenso
@buonsenso.bsky.social
3.7K followers 100 following 520 posts
Pediatric Infectious Disease doctor.
Fighting to care for children with Long Covid & ME/CFS.
My book on my LONG COVID JOURNEY: https://tinyurl.com/4tsvhwat
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buonsenso.bsky.social
Danilo Buonsenso @buonsenso.bsky.social · Nov 10
as I’m new here,
wanted to tell that I wrote a personal and sentimental book on #longcovid
LONG COVID - MY NO-FILTER TRAVEL JOURNAL

tinyurl.com/4tsvhwat

I retrace main steps under my perspective and no filters, highlighting both the professional and human satisfactions, but also the difficulties
buonsenso.bsky.social
Long COVID, Immune Dysregulation & What It Means for Kids — New Insights and Future Therapies

danilobuonsenso.substack.com/p/long-covid...
Long COVID, Immune Dysregulation & What It Means for Kids — New Insights and Future Therapies
Long COVID isn’t just a collection of lingering symptoms — it may reflect deep changes in the immune system that can persist for years.
danilobuonsenso.substack.com
December 28, 2025 at 3:21 PM
buonsenso.bsky.social
When I started the #longcovid in kids journey we were literally alone.
Now, we arrived to speak about long covid in children in @TheLancetInfDis Podcast!❤️

MY LONG COVID JOURNEY, WHAT I DO AND WHY IN MY BOOK: tinyurl.com/4tsvhwat

🔊 Spotify: bit.ly/4p7jnpy
December 22, 2025 at 1:57 PM
buonsenso.bsky.social
You Are Not Alone – Let’s Connect Families, Young People and Communities Living with Long Covid and ME/CFS

danilobuonsenso.substack.com/p/you-are-no...
You Are Not Alone – Let’s Connect Families, Young People and Communities Living with Long Covid and ME/CFS
When a child, teenager, or young adult develops Long Covid or ME/CFS, the world can suddenly become very small.
danilobuonsenso.substack.com
December 14, 2025 at 4:15 PM
buonsenso.bsky.social
a new major study on Nature immunology further reinforces the overwhelming evidence of chronic immune activation in #longcovid, perfectly justifying off label use of immune modulators (eg IVIG) in the most severe cases that cannot access trials.
Saying since a few years in my book

lnkd.in/dPHkH3re
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
December 14, 2025 at 9:06 AM
buonsenso.bsky.social
So the Pediatric Infectious Diseases games are ready to go in 2d!
Impressive amount of different european countries participating this year!
December 9, 2025 at 8:23 PM
buonsenso.bsky.social
When Patients Ask for a Cure: A Doctor’s Honest Reflection on Long Covid and ME/CFS

danilobuonsenso.substack.com/p/when-patie...
When Patients Ask for a Cure: A Doctor’s Honest Reflection on Long Covid and ME/CFS
In the past months, my inbox (and whatsapp!) has filled with messages from patients and families living with Long Covid or ME/CFS.
danilobuonsenso.substack.com
December 7, 2025 at 5:23 PM
buonsenso.bsky.social
Oxaloacetate, long COVID and ME/CFS: what the new trial shows — and a pragmatic (non-prescriptive) scheme for clinicians

danilobuonsenso.substack.com/p/oxaloaceta...
Oxaloacetate, long COVID and ME/CFS: what the new trial shows — and a pragmatic (non-prescriptive) scheme for clinicians
Fatigue and cognitive fog remain among the most disabling complaints for people with long COVID and with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
danilobuonsenso.substack.com
November 30, 2025 at 5:16 PM
buonsenso.bsky.social
with the only and one!!
daniellebeckman.bsky.social Danielle Beckman @daniellebeckman.bsky.social · Nov 21
Finally met @buonsenso.bsky.social in person and got an update from one of the best researchers in #LongCovidKids. Kids with hypometabolism in the orbitofrontal cortex, the same region of the brain where I see the virus in the🔬. It is not even fully developed until we reach 25 years old..
November 23, 2025 at 3:25 PM
buonsenso.bsky.social
Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution

danilobuonsenso.substack.com/p/low-dose-r...
Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution
Over the past months, I have written several posts exploring the potential role of low-dose rapamycin in Long COVID and ME/CFS (Part 1, Part 2, Part 3).
danilobuonsenso.substack.com
November 23, 2025 at 3:25 PM
buonsenso.bsky.social
What’s new in the Long COVID / ME/CFS endothelial story — and what that means for treatment

danilobuonsenso.substack.com/p/whats-new-...
What’s new in the Long COVID / ME/CFS endothelial story — and what that means for treatment
You may remember that in earlier posts we discussed how both Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) appear to share a key feature: endothelial inflammation/dysfunct...
danilobuonsenso.substack.com
November 16, 2025 at 3:10 PM
buonsenso.bsky.social
you’ll read several success papers about #nirsevimab and #RSV but to make it a successful and long term sustainable interventions you need to read also of out chorus provocative voices, like this one !

rdcu.be/ePXTa
November 14, 2025 at 6:45 PM
buonsenso.bsky.social
Long COVID and the AMPA Pathway: New Clues from Brain Imaging

danilobuonsenso.substack.com/p/long-covid...
Long COVID and the AMPA Pathway: New Clues from Brain Imaging
Over the past few years, Long COVID has become one of the most puzzling and impactful conditions in post-viral medicine — especially for the many children and adults who continue to experience “brain ...
danilobuonsenso.substack.com
November 9, 2025 at 4:57 PM
buonsenso.bsky.social
Conversations on IVIG and Monoclonals in #LongCovid #MECFS

danilobuonsenso.substack.com/p/conversati...
Conversations on IVIG and Monoclonals
A recording from MD, PhD's live video
danilobuonsenso.substack.com
November 3, 2025 at 4:00 PM
buonsenso.bsky.social
new on covid impact on kids

www.tandfonline.com/eprint/ZY2VI...
The second-order effects that the COVID-19 pandemic has had on pediatric populations
SARS-CoV-2 can have long-term health consequences that persist beyond acute infection. While this is evident in adults and the elderly, the impact on children and adolescents remains under recogniz...
www.tandfonline.com
November 1, 2025 at 8:01 AM
Reposted by Danilo Buonsenso
torres-amy.bsky.social
The latest from @buonsenso.bsky.social rings so true:

Yet when patients and families ask for treatments, the answer is almost always: “There are no approved options.”

open.substack.com/pub/danilobu...

#PedSky
#LongCovidKids
#pwLC
#pwME
When There Are No Treatments: Why Off-Label Drugs Should Be on the Table for Long Covid and ME/CFS
What Does “Off-Label” Really Mean?
open.substack.com
October 26, 2025 at 2:58 PM
buonsenso.bsky.social
glad our team contributed to another very important study on iGAS.
PEGASUS network

www.sciencedirect.com/science/arti...
Paediatric invasive group A streptococcal infections and associations with viral infections in 15 European countries after lifting non-pharmaceutical interventions against SARS-CoV-2: an interrupted t...
After lifting non-pharmaceutical interventions (NPIs) against the transmission of SARS-CoV-2, various countries experienced an increase in invasive Gr…
www.sciencedirect.com
October 22, 2025 at 1:17 PM
buonsenso.bsky.social
“We Can’t Do This Alone”: A Doctor’s Plea for Support in Caring for Long COVID and ME/CFS Patients

danilobuonsenso.substack.com/p/we-cant-do...
“We Can’t Do This Alone”: A Doctor’s Plea for Support in Caring for Long COVID and ME/CFS Patients
As a pediatrician and infectious disease specialist, my days are full.
danilobuonsenso.substack.com
October 19, 2025 at 1:50 PM
buonsenso.bsky.social
again viruses and dementia.
those of you negating this slow science progression and patients prevention options.

all started w #LongCovid revolution. years ago I said LC is clearly giving this indication and now science is confirming

all in my book: tinyurl.com/4tsvhwat
October 15, 2025 at 8:44 AM
buonsenso.bsky.social
Working (and Keeping Your Salary) When Long COVID or ME/CFS Makes Full-Time Work Impossible

danilobuonsenso.substack.com/p/working-an...
Working (and Keeping Your Salary) When Long COVID or ME/CFS Makes Full-Time Work Impossible
1.
danilobuonsenso.substack.com
October 12, 2025 at 3:09 PM
buonsenso.bsky.social
I have a strongest feeling and growing evidence that lung ultrasound will play a growing role not only in diagnosing pneumonia but also in understanding which cases need antibiotics

rdcu.be/eJ1tQ
Point-of-care lung ultrasound to differentiate bacterial and viral lower respiratory tract infections in pediatric age: a multicenter prospective observational study
Scientific Reports - Point-of-care lung ultrasound to differentiate bacterial and viral lower respiratory tract infections in pediatric age: a multicenter prospective observational study
rdcu.be
October 8, 2025 at 7:59 PM
buonsenso.bsky.social
Can IV Saline Help Kids and Adults with ME/CFS?

danilobuonsenso.substack.com/p/can-iv-sal...
Can IV Saline Help Kids and Adults with ME/CFS?
Living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) can be exhausting, not only because of the illness itself but also because of the limited treatment options available.
danilobuonsenso.substack.com
October 5, 2025 at 1:35 PM
buonsenso.bsky.social
glad @TheLancetInfDis gave #LongCovid kids the voice they deserve, and with a powerful title as I love.
that’s a big change compared with the past

t.co/TyOo8jmQOr
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00496-7/fulltext
t.co
October 2, 2025 at 7:01 AM
Reposted by Danilo Buonsenso
longcovidkids.bsky.social
The Lancet @buonsenso.bsky.social

The take-home message from this study is clear: long COVID is here to stay, even in children, and can be exacerbated by reinfections and sustained by high viral circulation. Governments, health-care systems, and

#LongCovidKids

www.thelancet.com/journals/lan...
October 2, 2025 at 4:27 AM
buonsenso.bsky.social
Helping Your Child Through Long Covid or ME/CFS: What Parents Can Do, Age by Age

danilobuonsenso.substack.com/p/helping-yo...
Helping Your Child Through Long Covid or ME/CFS: What Parents Can Do, Age by Age
Long Covid and ME/CFS can affect children, adolescents, and young adults in profoundly different ways.
danilobuonsenso.substack.com
September 28, 2025 at 2:43 PM
buonsenso.bsky.social
Nasal Azelastine and COVID Prevention: What a New Study Tells Us — And Why It Might Matter for Long COVID / ME/CFS

danilobuonsenso.substack.com/p/nasal-azel...
Nasal Azelastine and COVID Prevention: What a New Study Tells Us — And Why It Might Matter for Long COVID / ME/CFS
Introduction
danilobuonsenso.substack.com
September 21, 2025 at 8:29 PM