@rungek.bsky.social
Schizosaccharomyces and formerly Saccharomyces researcher; interested in telomeres, DNA double-strand breaks, DNA damage response the cdk Pef1 (cdk5 in humans).
Reposted
Reposted
Interesting to see new papers connecting Pol II stalling to heterochromatin formation.
www.cell.com/molecular-ce...
Reminiscent of our work in S. pombe:
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.cell.com/molecular-ce...
Reminiscent of our work in S. pombe:
pmc.ncbi.nlm.nih.gov/articles/PMC...
The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin
Wu et al. reveal that the SFiNX complex triggers transposon silencing through the
association of Sov with two transcription termination factors, PNUTS and Senataxin,
leading to RNA Pol II stalling. Th...
www.cell.com
October 29, 2025 at 3:47 PM
Interesting to see new papers connecting Pol II stalling to heterochromatin formation.
www.cell.com/molecular-ce...
Reminiscent of our work in S. pombe:
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.cell.com/molecular-ce...
Reminiscent of our work in S. pombe:
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted
🔬 #imageoftheweek ¦ Candida albicans goliath cells
Goliath cells are oversized, ultra-sticky yeast cells formed when Candida albicans is starved of zinc. They cling to plastic and build biofilms, making them a potential culprit in hospital infections. 🧫
🔗 buff.ly/JikHPLM
📸 Iana Kalinina
Goliath cells are oversized, ultra-sticky yeast cells formed when Candida albicans is starved of zinc. They cling to plastic and build biofilms, making them a potential culprit in hospital infections. 🧫
🔗 buff.ly/JikHPLM
📸 Iana Kalinina
October 17, 2025 at 8:42 AM
🔬 #imageoftheweek ¦ Candida albicans goliath cells
Goliath cells are oversized, ultra-sticky yeast cells formed when Candida albicans is starved of zinc. They cling to plastic and build biofilms, making them a potential culprit in hospital infections. 🧫
🔗 buff.ly/JikHPLM
📸 Iana Kalinina
Goliath cells are oversized, ultra-sticky yeast cells formed when Candida albicans is starved of zinc. They cling to plastic and build biofilms, making them a potential culprit in hospital infections. 🧫
🔗 buff.ly/JikHPLM
📸 Iana Kalinina
Reposted
as a reminder: bluesky (the app) has a broad set of user interactions controls.
beyond blocking and block lists, we have features to control who can reply, mention, and quote-post accounts
beyond blocking and block lists, we have features to control who can reply, mention, and quote-post accounts
October 17, 2025 at 10:13 PM
as a reminder: bluesky (the app) has a broad set of user interactions controls.
beyond blocking and block lists, we have features to control who can reply, mention, and quote-post accounts
beyond blocking and block lists, we have features to control who can reply, mention, and quote-post accounts
Reposted
Reposted
A CDC report found that among pregnant U.S. women with COVID-19, 1 in 80 deliveries resulted in stillbirth, compared to 1 in 155 for uninfected women--- but under new leadership, the CDC isn't telling you that.
apnews.com/article/cor...
apnews.com/article/cor...
Coronavirus can destroy the placenta and lead to stillbirths
New research suggests the coronavirus can invade and destroy the placenta and lead to stillbirths in infected women.
apnews.com
May 27, 2025 at 11:12 PM
A CDC report found that among pregnant U.S. women with COVID-19, 1 in 80 deliveries resulted in stillbirth, compared to 1 in 155 for uninfected women--- but under new leadership, the CDC isn't telling you that.
apnews.com/article/cor...
apnews.com/article/cor...
Reposted
The loss data (~$10B) support and N of grants terminated is updated below, but this op-ed by @euanashley.bsky.social hits all the important points @latimes.com @stanfordmedicine.bsky.social
www.latimes.com/opinion/stor...
www.latimes.com/opinion/stor...
May 28, 2025 at 2:27 PM
The loss data (~$10B) support and N of grants terminated is updated below, but this op-ed by @euanashley.bsky.social hits all the important points @latimes.com @stanfordmedicine.bsky.social
www.latimes.com/opinion/stor...
www.latimes.com/opinion/stor...
Reposted
WOW. Federal judge orders the release of Kseniia Petrova, the Russian researcher detained by ICE for months and recently charged for allegedly smuggling frog embryos into the United States.
CR:…Demore v. Kim…
no court ruled removal undertaken for arbitary and capricious…
The COURT FINDS BY CLEAR AND CONVINCING EVIDENCE IS NOT A DANGER OR A RISK AND HEREBY GRANTS RELEASE FROM ICE/HSI CUSTODY.
no court ruled removal undertaken for arbitary and capricious…
The COURT FINDS BY CLEAR AND CONVINCING EVIDENCE IS NOT A DANGER OR A RISK AND HEREBY GRANTS RELEASE FROM ICE/HSI CUSTODY.
May 28, 2025 at 3:50 PM
WOW. Federal judge orders the release of Kseniia Petrova, the Russian researcher detained by ICE for months and recently charged for allegedly smuggling frog embryos into the United States.
Reposted
Trump's DOJ has granted Boeing a non-prosecution agreement over the 737 MAX crashes, despite the company's repeated attempts to deceive regulators.
Boeing donated $1M to Trump's inauguration and has paid AG Pam Bondi's former lobbying firm at least $480K.
Follow the money.
Boeing donated $1M to Trump's inauguration and has paid AG Pam Bondi's former lobbying firm at least $480K.
Follow the money.
How to kill 346 people and get away with it
On October 29, 2018, a Boeing 737 MAX operated by Lion Air crashed into the Java Sea about 13 minutes after taking off f
popular.info
May 27, 2025 at 11:30 PM
Trump's DOJ has granted Boeing a non-prosecution agreement over the 737 MAX crashes, despite the company's repeated attempts to deceive regulators.
Boeing donated $1M to Trump's inauguration and has paid AG Pam Bondi's former lobbying firm at least $480K.
Follow the money.
Boeing donated $1M to Trump's inauguration and has paid AG Pam Bondi's former lobbying firm at least $480K.
Follow the money.
Reposted
50+% cut to the US National Science Foundation budget is staggering. These include cuts for research in Chemistry. Physics, Geology, Math, Engineering, Computer Science.
Scientific discoveries and training of our next generation of scientists and engineers are halved.
How is that helping the US?
Scientific discoveries and training of our next generation of scientists and engineers are halved.
How is that helping the US?
May 28, 2025 at 12:48 PM
50+% cut to the US National Science Foundation budget is staggering. These include cuts for research in Chemistry. Physics, Geology, Math, Engineering, Computer Science.
Scientific discoveries and training of our next generation of scientists and engineers are halved.
How is that helping the US?
Scientific discoveries and training of our next generation of scientists and engineers are halved.
How is that helping the US?
Reposted
Just out - a collaborative effort examining gene family evolution across yeast species. We found that fast-evolving yeasts lose more genes - especially ones for splicing, metabolism, and cell division. This is consistent with their narrow metabolic niche breadth.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Unique trajectory of gene family evolution from genomic analysis of nearly all known species in an ancient yeast lineage | Molecular Systems Biology
imageimageLarge-scale comparison of gene families across 1154 Saccharomycotina genomes revealed
that gene gains and losses drive yeast evolution. Faster-evolving lineages lose more
genes and speciate ...
www.embopress.org
May 27, 2025 at 6:31 PM
Just out - a collaborative effort examining gene family evolution across yeast species. We found that fast-evolving yeasts lose more genes - especially ones for splicing, metabolism, and cell division. This is consistent with their narrow metabolic niche breadth.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Reposted
Researchers have developed new tools that can deliver genes and selectively activate them in hundreds of different cell types in the brain and spinal cord. Scientists hope this could help treat ALS, Parkinson’s disease and Alzheimer’s.
Scientists develop gene delivery ‘trucks’ that could treat brain diseases
Gene delivery systems can target specific brain cells, a breakthrough that could lead to treatments for Parkinson's, Alzheimer's and other neurodegenerative diseases.
wapo.st
May 28, 2025 at 7:10 PM
Researchers have developed new tools that can deliver genes and selectively activate them in hundreds of different cell types in the brain and spinal cord. Scientists hope this could help treat ALS, Parkinson’s disease and Alzheimer’s.
Reposted
428.95 parts per million (ppm) CO2 in air 27-May-2025 keelingcurve.ucsd.edu
The Keeling Curve
The Keeling Curve is a daily record of global atmospheric carbon dioxide concentration maintained by Scripps Institution of Oceanography at UC San Diego.
keelingcurve.ucsd.edu
May 28, 2025 at 4:11 PM
428.95 parts per million (ppm) CO2 in air 27-May-2025 keelingcurve.ucsd.edu
Washington Post opinion editor departs as Bezos pushes to promote ‘personal liberties and free markets’
Bezos takes another big leap toward become another Fox News lie machine. Time to drop the Washington Post subscription and give those dollars to the Guardian.
Bezos takes another big leap toward become another Fox News lie machine. Time to drop the Washington Post subscription and give those dollars to the Guardian.
February 26, 2025 at 7:26 PM
Washington Post opinion editor departs as Bezos pushes to promote ‘personal liberties and free markets’
Bezos takes another big leap toward become another Fox News lie machine. Time to drop the Washington Post subscription and give those dollars to the Guardian.
Bezos takes another big leap toward become another Fox News lie machine. Time to drop the Washington Post subscription and give those dollars to the Guardian.
Interesting legal musings via Good Science Project about NIH indirect cost rate cuts
Good read from a lawyer. goodscience.substack.com/p/indirect-c...
Good read from a lawyer. goodscience.substack.com/p/indirect-c...
Indirect Costs at NIH . . .
I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night:
goodscience.substack.com
February 9, 2025 at 7:06 PM
Interesting legal musings via Good Science Project about NIH indirect cost rate cuts
Good read from a lawyer. goodscience.substack.com/p/indirect-c...
Good read from a lawyer. goodscience.substack.com/p/indirect-c...