Milo B. Fasken, Ph.D.
@milofasken.bsky.social
Senior Scientist, Department of Biology, Emory University, Atlanta, GA.
Molecular Biologist. RNA Scientist. Yeast Geneticist 🧬. British🇬🇧. Runner 🏃🏻…. Opinions are my own.
Interests: RNA Decay, RNA Processing, RNA & Disease.
Molecular Biologist. RNA Scientist. Yeast Geneticist 🧬. British🇬🇧. Runner 🏃🏻…. Opinions are my own.
Interests: RNA Decay, RNA Processing, RNA & Disease.
Pinned
Glad to have joined Bluesky yesterday! Great to have followed so many old and new friends/colleagues. Looking forward to all the great RNA biology and fun science chats!
#RNA #RNASky
P.S. Are there any Starter Packs for model organisms, especially, #BuddingYeast #Scerevisiae?
#RNA #RNASky
P.S. Are there any Starter Packs for model organisms, especially, #BuddingYeast #Scerevisiae?
Happy New Year! Wishing everybody some “Good Science” for 2026! 🧬😊
January 1, 2026 at 4:15 PM
Happy New Year! Wishing everybody some “Good Science” for 2026! 🧬😊
Happy Holidays!
December 25, 2025 at 2:00 PM
Happy Holidays!
Reposted by Milo B. Fasken, Ph.D.
My "News & views" was published today @natmethods.nature.com
Thanks @ritastrack.bsky.social for the invitation to write it and Allison Doerr for the editing after Rita left...
www.nature.com/articles/s41...
Thanks @ritastrack.bsky.social for the invitation to write it and Allison Doerr for the editing after Rita left...
www.nature.com/articles/s41...
Targeted RNA-binding protein degradation to improve mRNA live imaging in animal cells - Nature Methods
The gold standard system for mRNA imaging in live cells just got upgraded by being degraded. This development improves signal-to-noise ratios and may lead to a better understanding of mRNA transport a...
www.nature.com
December 17, 2025 at 11:13 AM
My "News & views" was published today @natmethods.nature.com
Thanks @ritastrack.bsky.social for the invitation to write it and Allison Doerr for the editing after Rita left...
www.nature.com/articles/s41...
Thanks @ritastrack.bsky.social for the invitation to write it and Allison Doerr for the editing after Rita left...
www.nature.com/articles/s41...
Reposted by Milo B. Fasken, Ph.D.
My talk from the latest RNA Collaborative Seminar Series is now available on YouTube. The second talk in the session was given by Rachel Braun (Sara Cherry’s lab) on TTP and its role in regulating antiviral immunity. youtu.be/2Aj-xbi3dPI #RNAsky #RNAbiology
December 10: NCI RNA Biology Initiative & Penn Institute for RNA Innovation
YouTube video by RNA Collaborative Seminar Series
youtu.be
December 12, 2025 at 5:59 PM
My talk from the latest RNA Collaborative Seminar Series is now available on YouTube. The second talk in the session was given by Rachel Braun (Sara Cherry’s lab) on TTP and its role in regulating antiviral immunity. youtu.be/2Aj-xbi3dPI #RNAsky #RNAbiology
Why Does A.I. Write Like … That? www.nytimes.com/2025/12/03/m...
Why Does A.I. Write Like … That?
www.nytimes.com
December 7, 2025 at 4:56 PM
Why Does A.I. Write Like … That? www.nytimes.com/2025/12/03/m...
Nice work!
#mRNP #Condensation #Stress #Yeast
Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs: Molecular Cell www.cell.com/molecular-ce...
#mRNP #Condensation #Stress #Yeast
Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs: Molecular Cell www.cell.com/molecular-ce...
Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs
Glauninger, Bard, Wong Hickernell, et al. reveal that stress causes transcriptome-wide
mRNP condensation, largely independent of length and often without stress granule
formation, but newly synthesize...
www.cell.com
December 1, 2025 at 11:51 PM
Nice work!
#mRNP #Condensation #Stress #Yeast
Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs: Molecular Cell www.cell.com/molecular-ce...
#mRNP #Condensation #Stress #Yeast
Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs: Molecular Cell www.cell.com/molecular-ce...
Nice work!
#mRNP #Condensation #Stress #Yeast
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress: Molecular Cell www.cell.com/molecular-ce...
#mRNP #Condensation #Stress #Yeast
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress: Molecular Cell www.cell.com/molecular-ce...
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress
Under stress, cells adapt their gene expression programs through changes in transcription
and translation. It is unclear how cells determine which mRNAs are translated or repressed.
Zedan et al. show ...
www.cell.com
December 1, 2025 at 11:50 PM
Nice work!
#mRNP #Condensation #Stress #Yeast
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress: Molecular Cell www.cell.com/molecular-ce...
#mRNP #Condensation #Stress #Yeast
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress: Molecular Cell www.cell.com/molecular-ce...
I wanted to say thanks for your paper as well and congrats to your student! Wonderfully thorough and mechanistic story. It brought me great joy to see evidence that Nrd1 could bind to a mRNA independent of Nab3 in vivo. The phenotypic consequences of mutating Nab3 binding sites on PIC2 are amazing!😊
November 22, 2025 at 12:32 PM
I wanted to say thanks for your paper as well and congrats to your student! Wonderfully thorough and mechanistic story. It brought me great joy to see evidence that Nrd1 could bind to a mRNA independent of Nab3 in vivo. The phenotypic consequences of mutating Nab3 binding sites on PIC2 are amazing!😊
Nice work! #Nab3 #Nrd1 #Sen1 #NNS
A transcription termination mechanism for maintaining homogeneous protein expression url: academic.oup.com/nar/article/...
A transcription termination mechanism for maintaining homogeneous protein expression url: academic.oup.com/nar/article/...
A transcription termination mechanism for maintaining homogeneous protein expression
Abstract. Premature transcription termination is a critical mechanism for repressing harmful, unproductive transcription. In Saccharomyces cerevisiae, prem
academic.oup.com
November 20, 2025 at 6:18 PM
Nice work! #Nab3 #Nrd1 #Sen1 #NNS
A transcription termination mechanism for maintaining homogeneous protein expression url: academic.oup.com/nar/article/...
A transcription termination mechanism for maintaining homogeneous protein expression url: academic.oup.com/nar/article/...
www.nature.com
October 31, 2025 at 10:59 AM
Reposted by Milo B. Fasken, Ph.D.
Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...
Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology
As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.
www.nature.com
October 11, 2025 at 8:03 AM
Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...
Time-resolved fluorescent proteins expand #fluorescent #microscopy in temporal and spectral domains: Cell www.cell.com/cell/fulltex...
Time-resolved fluorescent proteins expand fluorescent microscopy in temporal and spectral domains
(Cell 188, ◼◼◼–◼◼◼.e1–e14; November 26, 2025)
www.cell.com
October 3, 2025 at 1:00 PM
Time-resolved fluorescent proteins expand #fluorescent #microscopy in temporal and spectral domains: Cell www.cell.com/cell/fulltex...
Nice review on #PCH #Disease
Pontocerebellar hypoplasia: a review from 1912 to 2022 url: academic.oup.com/braincomms/a...
Pontocerebellar hypoplasia: a review from 1912 to 2022 url: academic.oup.com/braincomms/a...
Pontocerebellar hypoplasia: a review from 1912 to 2022
Kukulka et al. report that pontocerebellar hypoplasia is most often linked to mutations in TSEN54, RARS2, EXOSC3 and AMPD2, with Types 1, 2, and 6 being mo
academic.oup.com
September 13, 2025 at 11:16 PM
Nice review on #PCH #Disease
Pontocerebellar hypoplasia: a review from 1912 to 2022 url: academic.oup.com/braincomms/a...
Pontocerebellar hypoplasia: a review from 1912 to 2022 url: academic.oup.com/braincomms/a...