René Ketting
@reneketting.bsky.social
IMB Mainz, Germany
RNA; Small RNAs; Germ cells; Transposons; Germ granules; nematodes; zebrafish
Posts reflect my personal opinion
RNA; Small RNAs; Germ cells; Transposons; Germ granules; nematodes; zebrafish
Posts reflect my personal opinion
Very happy to be able to advertise our latest paper:
A genetic framework for RNAi inheritance in Caenorhabditis elegans | EMBO reports www.embopress.org/doi/full/10....
A genetic framework for RNAi inheritance in Caenorhabditis elegans | EMBO reports www.embopress.org/doi/full/10....
A genetic framework for RNAi inheritance in Caenorhabditis elegans | EMBO reports
imageimageAn intergenerational cycle between HRDE-1 and WAGO-3 drives RNAi inheritance in C. elegans, where HRDE-1 drives silencing in both parent and offspring and WAGO-3 transmits
the RNAi response ...
www.embopress.org
July 7, 2025 at 12:47 PM
Very happy to be able to advertise our latest paper:
A genetic framework for RNAi inheritance in Caenorhabditis elegans | EMBO reports www.embopress.org/doi/full/10....
A genetic framework for RNAi inheritance in Caenorhabditis elegans | EMBO reports www.embopress.org/doi/full/10....
Reposted by René Ketting
If you are an enthusiastic, motivated and team-oriented life science researcher-in-spé, we are looking for you! We offer excellent science and working conditions. For more info on projects please see. Please help me spread this🙏
www.imb.de/students-pos...
www.imb.de/students-pos...
February 14, 2025 at 12:59 PM
If you are an enthusiastic, motivated and team-oriented life science researcher-in-spé, we are looking for you! We offer excellent science and working conditions. For more info on projects please see. Please help me spread this🙏
www.imb.de/students-pos...
www.imb.de/students-pos...
If you are an enthusiastic, motivated and team-oriented life science researcher-in-spé, we are looking for you! We offer excellent science and working conditions. For more info on projects please see. Please help me spread this🙏
www.imb.de/students-pos...
www.imb.de/students-pos...
February 14, 2025 at 12:59 PM
If you are an enthusiastic, motivated and team-oriented life science researcher-in-spé, we are looking for you! We offer excellent science and working conditions. For more info on projects please see. Please help me spread this🙏
www.imb.de/students-pos...
www.imb.de/students-pos...
Reposted by René Ketting
💥Finally out!
Answering a two-centuries old question about a membraneless organelle that forms in #oocytes from insects to humans: the Balbiani body (Bb).
Now in
@currentbiology.bsky.social
:
cell.com/current-biol...
>
Answering a two-centuries old question about a membraneless organelle that forms in #oocytes from insects to humans: the Balbiani body (Bb).
Now in
@currentbiology.bsky.social
:
cell.com/current-biol...
>
The Balbiani body is formed by microtubule-controlled molecular condensation of Buc in early oogenesis
Kar et al. demonstrate that Balbiani body (Bb) formation is achieved via developmental condensation in zebrafish oogenesis, driven by Buc phase separation and evolving from a dynamic liquid-like state into a solid-like stable compartment. Multistep regulation by microtubules controls condensation, ensuring proper Bb formation and oocyte polarity.
cell.com
January 9, 2025 at 5:24 PM
💥Finally out!
Answering a two-centuries old question about a membraneless organelle that forms in #oocytes from insects to humans: the Balbiani body (Bb).
Now in
@currentbiology.bsky.social
:
cell.com/current-biol...
>
Answering a two-centuries old question about a membraneless organelle that forms in #oocytes from insects to humans: the Balbiani body (Bb).
Now in
@currentbiology.bsky.social
:
cell.com/current-biol...
>
Reposted by René Ketting
First #bluetorial. 🎉🎉 We’re very happy to share our latest biorxiv #preprint, just in time before the holiday season. We explored how transposable elements (TEs) diversify eukaryotic proteomes and found a cool case in nematode F-box genes. #TEsky #evosky #Celegans
Short 🧵 with highlights.
Short 🧵 with highlights.
December 19, 2024 at 12:35 PM
First #bluetorial. 🎉🎉 We’re very happy to share our latest biorxiv #preprint, just in time before the holiday season. We explored how transposable elements (TEs) diversify eukaryotic proteomes and found a cool case in nematode F-box genes. #TEsky #evosky #Celegans
Short 🧵 with highlights.
Short 🧵 with highlights.
Reposted by René Ketting
Transposable elements drive regulatory and functional innovation of F-box genes https://www.biorxiv.org/content/10.1101/2024.12.17.628972v1
December 18, 2024 at 12:32 PM
Transposable elements drive regulatory and functional innovation of F-box genes https://www.biorxiv.org/content/10.1101/2024.12.17.628972v1
www.academics.com/jobs/univers...
Please help us find a new colleague at Mainz University. Thanks!
#evolbiol
Please help us find a new colleague at Mainz University. Thanks!
#evolbiol
University Professor of Life History Evolution W3 - Johannes Gutenberg-Universität Mainz
Johannes Gutenberg-Universität Mainz looks for University Professor of Life History Evolution W3 in Mainz - apply now!
www.academics.com
December 18, 2024 at 1:57 PM
www.academics.com/jobs/univers...
Please help us find a new colleague at Mainz University. Thanks!
#evolbiol
Please help us find a new colleague at Mainz University. Thanks!
#evolbiol
We are looking for new group leaders. If RNA is your thing, and/or computational biology and you want to start your own group, check out these links. Feel free to contact me about these!
And, please help me spread this. Thanks!
www.imb.de/jobs/jobdeta...
www.imb.de/jobs/jobdeta...
And, please help me spread this. Thanks!
www.imb.de/jobs/jobdeta...
www.imb.de/jobs/jobdeta...
Jobdetail
IMB Mainz
www.imb.de
December 14, 2024 at 10:13 AM
We are looking for new group leaders. If RNA is your thing, and/or computational biology and you want to start your own group, check out these links. Feel free to contact me about these!
And, please help me spread this. Thanks!
www.imb.de/jobs/jobdeta...
www.imb.de/jobs/jobdeta...
And, please help me spread this. Thanks!
www.imb.de/jobs/jobdeta...
www.imb.de/jobs/jobdeta...
Reposted by René Ketting
Universal Single Copy Knock-In System in Caenorhabditis elegans: One Plasmid to Target All Chromosomes https://www.biorxiv.org/content/10.1101/2024.12.06.627295v1
December 10, 2024 at 9:34 AM
Universal Single Copy Knock-In System in Caenorhabditis elegans: One Plasmid to Target All Chromosomes https://www.biorxiv.org/content/10.1101/2024.12.06.627295v1
Reposted by René Ketting
And since we're here... 🥼
Join us as a Group Leader in #ComputationalBiology or #RNA Biology 🧬
More details via www.imb.de/jobs
Application deadline is 5 January 2025
#sciencejobs #resilience #biostatistics
Join us as a Group Leader in #ComputationalBiology or #RNA Biology 🧬
More details via www.imb.de/jobs
Application deadline is 5 January 2025
#sciencejobs #resilience #biostatistics
November 28, 2024 at 10:31 AM
And since we're here... 🥼
Join us as a Group Leader in #ComputationalBiology or #RNA Biology 🧬
More details via www.imb.de/jobs
Application deadline is 5 January 2025
#sciencejobs #resilience #biostatistics
Join us as a Group Leader in #ComputationalBiology or #RNA Biology 🧬
More details via www.imb.de/jobs
Application deadline is 5 January 2025
#sciencejobs #resilience #biostatistics
Reposted by René Ketting
Join us in San Diego. A great meeting and also featuring the RNA Journal
Check it out! The RNA Society 2025 Meeting Site is now live! Registration will open in January RNASociety Note the fabulous artwork by former EmoryBCDB student Dr. Carly Lancaster- make your plans now to join us in San Diego May 27-June 1, 2025
November 19, 2024 at 7:27 AM
Join us in San Diego. A great meeting and also featuring the RNA Journal
Reposted by René Ketting
Researchers in @labgrosshans.bsky.social & their collaborators developed a tool that maps how proteases—enzymes that process proteins—cut their targets. The work, published in Molecular Systems Biology, could revolutionize drug design for conditions like diabetes. www.fmi.ch/news-events/...
New tool to map protease specificity may pave the way for improved treatments
FMI researchers have developed a new tool that maps how proteases —enzymes that process proteins— cut their targets. This innovation offers new insight into the highly selective nature of proteases, w...
www.fmi.ch
November 28, 2024 at 8:45 AM
Researchers in @labgrosshans.bsky.social & their collaborators developed a tool that maps how proteases—enzymes that process proteins—cut their targets. The work, published in Molecular Systems Biology, could revolutionize drug design for conditions like diabetes. www.fmi.ch/news-events/...
Reposted by René Ketting
And don't forget: many nematode species have lost them altogether! A huge puzzle.
doi.org/10.1002/wrna...
doi.org/10.1002/wrna...
November 24, 2024 at 2:54 PM
And don't forget: many nematode species have lost them altogether! A huge puzzle.
doi.org/10.1002/wrna...
doi.org/10.1002/wrna...
Reposted by René Ketting
Reposted by René Ketting
We are advertising two PhD positions in our lab on RNA splicing and modifications in development and cancer. NRPDTP project is open to international applicants. UEA project is for UK applicants only. With Yiliang Ding and Mark Williams www.findaphd.com/phds/?Keywor...
akay PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in akay. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
November 14, 2024 at 11:26 AM
Reposted by René Ketting
Small RNA Biology starter pack, with a heavy bias towards our worm community! Just getting this started, and we'd like it to max out, so please message me if I've missed you (and apologies!)! go.bsky.app/HgPCPen
November 12, 2024 at 2:24 AM
Small RNA Biology starter pack, with a heavy bias towards our worm community! Just getting this started, and we'd like it to max out, so please message me if I've missed you (and apologies!)! go.bsky.app/HgPCPen
Reposted by René Ketting
Excellent opportunity in Toronto.
We are recruiting! Princess Margaret Cancer Centre in Toronto is recruiting an early career cancer research scientist at Assistant Professor level. Apply! Spread the word!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Scientist I - Cancer Biology - Toronto (City), Ontario (CA) job with Princess Margaret Cancer Centre | 12831982
Princess Margaret seeks early-career faculty scientists to establish research programs in Cancer Biology - broadly defined.
www.nature.com
November 12, 2024 at 6:53 PM
Excellent opportunity in Toronto.
Question to worm colleagues: do you know of a transgene that starts to be transcribed in Z2/3, and is not provided maternally?
June 21, 2024 at 2:16 PM
Question to worm colleagues: do you know of a transgene that starts to be transcribed in Z2/3, and is not provided maternally?
Reposted by René Ketting
Happy to share the publication of the IDRome paper:
Conformational ensembles of the human intrinsically disordered proteome
Work led by Giulio Tesei and Anna Ida Trolle
I'll post more later, but for now here is a link:
www.nature.com/articles/s41...
Conformational ensembles of the human intrinsically disordered proteome
Work led by Giulio Tesei and Anna Ida Trolle
I'll post more later, but for now here is a link:
www.nature.com/articles/s41...
January 31, 2024 at 5:07 PM
Happy to share the publication of the IDRome paper:
Conformational ensembles of the human intrinsically disordered proteome
Work led by Giulio Tesei and Anna Ida Trolle
I'll post more later, but for now here is a link:
www.nature.com/articles/s41...
Conformational ensembles of the human intrinsically disordered proteome
Work led by Giulio Tesei and Anna Ida Trolle
I'll post more later, but for now here is a link:
www.nature.com/articles/s41...
New publication from our group: An extended Tudor domain within Vreteno interconnects Gtsf1L and Ago3 for piRNA biogenesis in Bombyx mori
www.embopress.org/doi/full/10....
We propose this may be how Piwi activity can be restricted environments suited for further piRNA production
www.embopress.org/doi/full/10....
We propose this may be how Piwi activity can be restricted environments suited for further piRNA production
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
November 21, 2023 at 3:31 PM
New publication from our group: An extended Tudor domain within Vreteno interconnects Gtsf1L and Ago3 for piRNA biogenesis in Bombyx mori
www.embopress.org/doi/full/10....
We propose this may be how Piwi activity can be restricted environments suited for further piRNA production
www.embopress.org/doi/full/10....
We propose this may be how Piwi activity can be restricted environments suited for further piRNA production
Reposted by René Ketting
Master's Thesis Opportunity! The Ameres lab is looking for a passionate master's student to delve into the mysteries of chemical RNA modifications ✨
➡️ Apply here: tinyurl.com/39hhkd7t
➡️ Apply here: tinyurl.com/39hhkd7t
November 2, 2023 at 3:30 PM
Master's Thesis Opportunity! The Ameres lab is looking for a passionate master's student to delve into the mysteries of chemical RNA modifications ✨
➡️ Apply here: tinyurl.com/39hhkd7t
➡️ Apply here: tinyurl.com/39hhkd7t
Reposted by René Ketting
🚨🚨🚨🤝🧬🔍 We are recruiting group leaders for the #GenomeBiologyDepartment at the I2BC (France). Open to all relevant topics, with particular interest in RNA biology, chromatin organization, genome stability and gene expression. i2bc.paris-saclay.fr/jobs/ DM me for info! Please RT🙏
November 1, 2023 at 3:40 PM
🚨🚨🚨🤝🧬🔍 We are recruiting group leaders for the #GenomeBiologyDepartment at the I2BC (France). Open to all relevant topics, with particular interest in RNA biology, chromatin organization, genome stability and gene expression. i2bc.paris-saclay.fr/jobs/ DM me for info! Please RT🙏
Reposted by René Ketting
The non-coding repetitive genome as a source of regulatory DNA elements in cancer: a highlight of the recent work from
Biswajyoti Sahu: www.nature.com/articles/s41...
Biswajyoti Sahu: www.nature.com/articles/s41...
Enhanced transposable elements - Nature Reviews Cancer
Karttunen et al. identify the contribution of transposable elements to gene regulatory function in colorectal and liver cancer cell lines.
www.nature.com
October 25, 2023 at 1:52 PM
The non-coding repetitive genome as a source of regulatory DNA elements in cancer: a highlight of the recent work from
Biswajyoti Sahu: www.nature.com/articles/s41...
Biswajyoti Sahu: www.nature.com/articles/s41...