Some (+)ve news to lighten another heavy weekend: our latest preprint (c/o Mattiroli + Ramani labs) is up!
www.biorxiv.org/content/10.1...
A tour-de-force by 1st authors Bruna Eckhardt & @palindromephd.bsky.social, focusing on chromatin replication. RTs welcome; tweetorial in 3,2...(1/n)

Fabulous post by @randomwalker.bsky.social & Sayash raising the same concern many of us have about whether we're on the right track with how we're using AI for science. Everyone should read it, take a deep breath & think through the implications.

www.aisnakeoil.com/p/could-ai-s...

We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab.
www.biorxiv.org/content/10.1...
1/

I am very excited to share our latest work where we describe a new method to profile genome-wide chromatin transitions over time in single cells. Great collaborative effort with the van Oudenaarden group @hubrechtinstitute.bsky.social @oncodeinstitute.bsky.social www.nature.com/articles/s41....

An AI model developed by Google DeepMind could help scientists make sense of the non-protein-coding part of the genome

https://go.nature.com/4llASRk

3D bioprinting innovation and the patentability hurdle - @uqlaw.bsky.social go.nature.com/4dsBr9i

Introducing FISHnet, a graph-theory-based method for sensitive and specific identification of chromatin domains from single-cell sequential Oligopaints data.

www.nature.com/articles/s41...

It has been bittersweet last week, when we bid farewell to Pedro and Prasanthi who are embarking on a new adventure!🥹 Thanks a lot for all the hard work and high spirit!🙏