Valentin Flury
@flurylab.bsky.social
Research Group Leader, working on epigenetic memory, chromatin (replication) and transcription at the MPI-IE.
Reposted by Valentin Flury
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
John Innes Centre
jobs.jic.ac.uk
October 8, 2025 at 9:04 AM
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
Reposted by Valentin Flury
Very sad news, John Gurdon has died.
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
October 7, 2025 at 4:02 PM
Very sad news, John Gurdon has died.
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
It has been a lot of fun to present our research focus and get to know the @gfgenetik.bsky.social! Thank you so much for having me and organising this great symposium! Looking forward to the next one!
Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm.
September 28, 2025 at 2:38 PM
It has been a lot of fun to present our research focus and get to know the @gfgenetik.bsky.social! Thank you so much for having me and organising this great symposium! Looking forward to the next one!
Reposted by Valentin Flury
This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1....
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin
Subtelomeres are imperfect repeats adjacent to telomeres that are repressed by heterochromatin. Although essential for genome integrity, their repetitive nature has thwarted dissection of local hetero...
www.biorxiv.org
September 27, 2025 at 6:55 AM
This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1....
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
Reposted by Valentin Flury
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
September 22, 2025 at 6:27 PM
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Reposted by Valentin Flury
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
September 14, 2025 at 11:46 AM
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Reposted by Valentin Flury
We are hiring-join us!
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
September 8, 2025 at 10:31 AM
We are hiring-join us!
Reposted by Valentin Flury
Massive congratulations to @canaztekin.bsky.social for being awarded an ERC Starting Grant @erc.europa.eu ! 🎉 His "Signal to Regeneration" (SigReg) project will explore the potential of limb regeneration in mammals.
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
September 4, 2025 at 12:56 PM
Massive congratulations to @canaztekin.bsky.social for being awarded an ERC Starting Grant @erc.europa.eu ! 🎉 His "Signal to Regeneration" (SigReg) project will explore the potential of limb regeneration in mammals.
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
What a special moment!🙌🙌🙌
I am also very happy to share this good news my colleague @flurylab.bsky.social @mpi-ie.bsky.social 🥂🥂
🎊 Congratulations to Juliane Glaser (@julianeg.bsky.social) and Valentin Flury (@flurylab.bsky.social) on being awarded each an @erc.europa.eu Starting Grant! – #ERCStG
www.ie-freiburg.mpg.de/6057908/2025...
www.ie-freiburg.mpg.de/6057908/2025...
September 4, 2025 at 7:22 PM
What a special moment!🙌🙌🙌
Excited and very grateful to announce that I have been awarded an ERC Starting Grant by @erc.europa.eu! 🎉 This is a fantastic opportunity to further build my team at the Max Planck Institute of Immunobiology and Epigenetics (@mpi-ie.bsky.social) exploring new grounds in fundamental research:
📣 The ERC Starting Grant call results are out!
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
September 4, 2025 at 7:19 PM
Excited and very grateful to announce that I have been awarded an ERC Starting Grant by @erc.europa.eu! 🎉 This is a fantastic opportunity to further build my team at the Max Planck Institute of Immunobiology and Epigenetics (@mpi-ie.bsky.social) exploring new grounds in fundamental research:
Reposted by Valentin Flury
🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
Massive congratulations to @canaztekin.bsky.social for being awarded an ERC Starting Grant @erc.europa.eu ! 🎉 His "Signal to Regeneration" (SigReg) project will explore the potential of limb regeneration in mammals.
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
September 4, 2025 at 1:27 PM
🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
Reposted by Valentin Flury
We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
August 28, 2025 at 5:35 PM
We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Last week, we bid farewell to our Summer student Jean.🍹👋 It was great having you in the lab and we wish you all the best finishing your studies!🍀 See you soon!🥳
August 29, 2025 at 10:32 AM
Last week, we bid farewell to our Summer student Jean.🍹👋 It was great having you in the lab and we wish you all the best finishing your studies!🍀 See you soon!🥳
Reposted by Valentin Flury
It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it".
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
August 22, 2025 at 11:48 AM
It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it".
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
Reposted by Valentin Flury
📢 Excited to share my World View article, just published in @NatureSMB, where I reflect on returning to Czechia and building research group grounded in collaboration🤝, resilience and curiosity💡. www.nature.com/articles/s41...
https://nature.com/articles/s4159…
August 7, 2025 at 5:28 PM
📢 Excited to share my World View article, just published in @NatureSMB, where I reflect on returning to Czechia and building research group grounded in collaboration🤝, resilience and curiosity💡. www.nature.com/articles/s41...
Reposted by Valentin Flury
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
August 1, 2025 at 9:06 AM
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
Reposted by Valentin Flury
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Group Leader - Genome Biology Unit
Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 1:41 PM
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Valentin Flury
STUDY: Denmark tracked over a million children for 21 years, and found vaccines linked to zero extra cases of autism, asthma, or 48 other conditions.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
July 28, 2025 at 1:56 PM
STUDY: Denmark tracked over a million children for 21 years, and found vaccines linked to zero extra cases of autism, asthma, or 48 other conditions.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
Reposted by Valentin Flury
We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab.
www.biorxiv.org/content/10.1...
1/
www.biorxiv.org/content/10.1...
1/
July 15, 2025 at 8:11 AM
We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab.
www.biorxiv.org/content/10.1...
1/
www.biorxiv.org/content/10.1...
1/
Reposted by Valentin Flury
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 9, 2025 at 10:05 AM
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Reposted by Valentin Flury
All about the 2026 ERC grant application and evaluation process! ✍️
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
July 3, 2025 at 11:27 AM
All about the 2026 ERC grant application and evaluation process! ✍️
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
Reposted by Valentin Flury
📖 Happy to share our recent preprint! www.biorxiv.org/content/10.1... We discovered how SINEs are kept silent: the ChAHP protein complex acts as a molecular brake on POL III transcription retrotransposons. A 🧵:
ChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment
Short interspersed nuclear elements (SINEs) are abundant non-autonomous transposable elements derived from RNA polymerase III (POL III)-transcribed short non-coding RNAs. SINEs retain sequence feature...
www.biorxiv.org
July 3, 2025 at 6:18 AM
📖 Happy to share our recent preprint! www.biorxiv.org/content/10.1... We discovered how SINEs are kept silent: the ChAHP protein complex acts as a molecular brake on POL III transcription retrotransposons. A 🧵:
Reposted by Valentin Flury
If you are interested in working on chromatin and oogenesis in the mouse in beautiful Copenhagen, we are recruiting a postdoc!
jobportal.ku.dk/videnskabeli...
Please share!
jobportal.ku.dk/videnskabeli...
Please share!
Beetween
app.beetween.com
June 17, 2025 at 1:24 PM
If you are interested in working on chromatin and oogenesis in the mouse in beautiful Copenhagen, we are recruiting a postdoc!
jobportal.ku.dk/videnskabeli...
Please share!
jobportal.ku.dk/videnskabeli...
Please share!
Reposted by Valentin Flury
also anyone with an apt/house for rent in #freiburg, 4+ rooms, preferably Herdern, Güterbahnhof, Wiehre, ANY time, ANY price, SEND IT MY WAY
Incredibly grateful for this tremendous recognition by @humboldt-foundation.de and not possible without the strongest support from @uni-freiburg.de and many previous funding bodies that made our research possible
www.humboldt-foundation.de/en/explore/n...
www.humboldt-foundation.de/en/explore/n...
June 5, 2025 at 4:33 PM
also anyone with an apt/house for rent in #freiburg, 4+ rooms, preferably Herdern, Güterbahnhof, Wiehre, ANY time, ANY price, SEND IT MY WAY
Reposted by Valentin Flury
📣 I will take up a Professorship at @uni-freiburg.de, Faculty of Biology. With amazing funding news coming in, we'll be in a position to establish a major research program around Epigenetics, Signaling and Synthetic Biology at the Signalhaus @cibss.bsky.social. More news and job ads to come soon!
June 5, 2025 at 8:51 AM
📣 I will take up a Professorship at @uni-freiburg.de, Faculty of Biology. With amazing funding news coming in, we'll be in a position to establish a major research program around Epigenetics, Signaling and Synthetic Biology at the Signalhaus @cibss.bsky.social. More news and job ads to come soon!