Megan Priestley
@megtriesscience.bsky.social
Postdoc fellow in the Stark Lab @ MIT. Researching the role of glycans in cancer immunology 🦠
// previously University of Manchester
// previously University of Manchester
Pinned
My PhD work is (finally) published in Science Signaling! And it made the cover!
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Reposted by Megan Priestley
New findings in #ScienceSignaling show that cells called leukocytes have a surface “coating” that can be modified during inflammatory conditions, such as #psoriasis, revealing how immune cells are recruited to sites of inflammation. https://scim.ag/4osBp5U
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.
scim.ag
November 7, 2025 at 4:00 PM
New findings in #ScienceSignaling show that cells called leukocytes have a surface “coating” that can be modified during inflammatory conditions, such as #psoriasis, revealing how immune cells are recruited to sites of inflammation. https://scim.ag/4osBp5U
Reposted by Megan Priestley
Congratulations to BLS Lecturer Dr Amy Saunders who has co-authored research featured on the front cover of this week's issue of #ScienceSignaling!
Dr Saunders' research has updated our understanding of how glycans help immune cells move into skin in psoriasis.
www.science.org/doi/10.1126/...
Dr Saunders' research has updated our understanding of how glycans help immune cells move into skin in psoriasis.
www.science.org/doi/10.1126/...
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.
www.science.org
November 6, 2025 at 3:40 PM
Congratulations to BLS Lecturer Dr Amy Saunders who has co-authored research featured on the front cover of this week's issue of #ScienceSignaling!
Dr Saunders' research has updated our understanding of how glycans help immune cells move into skin in psoriasis.
www.science.org/doi/10.1126/...
Dr Saunders' research has updated our understanding of how glycans help immune cells move into skin in psoriasis.
www.science.org/doi/10.1126/...
Reposted by Megan Priestley
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation | Science Signaling www.science.org/doi/10.1126/... 🧪
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.
www.science.org
November 4, 2025 at 8:12 PM
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation | Science Signaling www.science.org/doi/10.1126/... 🧪
Reposted by Megan Priestley
GAGs FTW! Wow #glycotime!! ⤵️🧪 🥳🥳
"Leukocyte recruitment is a key driver of inflammatory diseases, including psoriasis. Here, we found that leukocytes had the glycocalyx component heparan sulfate on their cell surface and that it was lost in response to psoriasis-like skin inflammation"
"Leukocyte recruitment is a key driver of inflammatory diseases, including psoriasis. Here, we found that leukocytes had the glycocalyx component heparan sulfate on their cell surface and that it was lost in response to psoriasis-like skin inflammation"
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate
www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social
www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.
www.science.org
November 5, 2025 at 8:05 AM
GAGs FTW! Wow #glycotime!! ⤵️🧪 🥳🥳
"Leukocyte recruitment is a key driver of inflammatory diseases, including psoriasis. Here, we found that leukocytes had the glycocalyx component heparan sulfate on their cell surface and that it was lost in response to psoriasis-like skin inflammation"
"Leukocyte recruitment is a key driver of inflammatory diseases, including psoriasis. Here, we found that leukocytes had the glycocalyx component heparan sulfate on their cell surface and that it was lost in response to psoriasis-like skin inflammation"
Reposted by Megan Priestley
Don’t miss this week’s issue of #ScienceSignaling!
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
November 4, 2025 at 10:00 PM
Don’t miss this week’s issue of #ScienceSignaling!
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
Reposted by Megan Priestley
What a week! So pleased to now also see the peer reviewed version in Science Signaling of @megtriesscience.bsky.social PhD work joint with the Saunders lab, see her great thread for explanation below www.science.org/doi/10.1126/...
November 4, 2025 at 8:06 PM
What a week! So pleased to now also see the peer reviewed version in Science Signaling of @megtriesscience.bsky.social PhD work joint with the Saunders lab, see her great thread for explanation below www.science.org/doi/10.1126/...
Reposted by Megan Priestley
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate
www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social
www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social
Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.
www.science.org
November 4, 2025 at 10:35 PM
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate
www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social
www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social
Reposted by Megan Priestley
👏 Congratulations to former Becker @wellcometrust.bsky.social ICD PhD student @megtriesscience.bsky.social on her first-author paper in Science Signaling!
My PhD work is (finally) published in Science Signaling! And it made the cover!
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
November 4, 2025 at 8:19 PM
👏 Congratulations to former Becker @wellcometrust.bsky.social ICD PhD student @megtriesscience.bsky.social on her first-author paper in Science Signaling!
Reposted by Megan Priestley
Great to see this story in print! Congrats @megtriesscience.bsky.social @douglaspdyer.bsky.social and team! Looking forward to sharing Megan's first contributions as a postdoc in our lab at @mitdeptofbe.bsky.social @mitcheme.bsky.social @mitkochinstitute.bsky.social soon... 👀
My PhD work is (finally) published in Science Signaling! And it made the cover!
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
November 4, 2025 at 8:03 PM
Great to see this story in print! Congrats @megtriesscience.bsky.social @douglaspdyer.bsky.social and team! Looking forward to sharing Megan's first contributions as a postdoc in our lab at @mitdeptofbe.bsky.social @mitcheme.bsky.social @mitkochinstitute.bsky.social soon... 👀
Reposted by Megan Priestley
Amazing work from @megtriesscience.bsky.social so proud of you and how this story has turned out!! @lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social
My PhD work is (finally) published in Science Signaling! And it made the cover!
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
November 4, 2025 at 7:57 PM
Amazing work from @megtriesscience.bsky.social so proud of you and how this story has turned out!! @lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social
My PhD work is (finally) published in Science Signaling! And it made the cover!
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
November 4, 2025 at 7:04 PM
My PhD work is (finally) published in Science Signaling! And it made the cover!
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
Here’s what we found 🧵⬇️
www.science.org/doi/10.1126/...
REGISTRATION FOR THE 2026 PROTEOGLYCANS GRS + GRC IS NOW OPEN! 🦠 (….and there’s a discount 😍)
Join us next summer for the GRS on Proteoglycans! We’re so excited to welcome our early career researchers that we’re giving the first 20 sign-ups a bursary towards their travel 🧵⬇️
Join us next summer for the GRS on Proteoglycans! We’re so excited to welcome our early career researchers that we’re giving the first 20 sign-ups a bursary towards their travel 🧵⬇️
September 24, 2025 at 2:11 PM
REGISTRATION FOR THE 2026 PROTEOGLYCANS GRS + GRC IS NOW OPEN! 🦠 (….and there’s a discount 😍)
Join us next summer for the GRS on Proteoglycans! We’re so excited to welcome our early career researchers that we’re giving the first 20 sign-ups a bursary towards their travel 🧵⬇️
Join us next summer for the GRS on Proteoglycans! We’re so excited to welcome our early career researchers that we’re giving the first 20 sign-ups a bursary towards their travel 🧵⬇️
Great opportunity available in my PhD lab! An exciting project with a really fun and supportive team 🦠
We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road
Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:
www.jobs.manchester.ac.uk
September 12, 2025 at 4:43 PM
Great opportunity available in my PhD lab! An exciting project with a really fun and supportive team 🦠
My first presentation as a postdoc! 🎙️
Yesterday I attended the KendallSqBio postdoc symposium where it was a pleasure to discover the cool work going on in our area as well as share what I’ve been up to with my lab’s new story on glycans in cancer! 🦠
Yesterday I attended the KendallSqBio postdoc symposium where it was a pleasure to discover the cool work going on in our area as well as share what I’ve been up to with my lab’s new story on glycans in cancer! 🦠
September 11, 2025 at 3:46 PM
My first presentation as a postdoc! 🎙️
Yesterday I attended the KendallSqBio postdoc symposium where it was a pleasure to discover the cool work going on in our area as well as share what I’ve been up to with my lab’s new story on glycans in cancer! 🦠
Yesterday I attended the KendallSqBio postdoc symposium where it was a pleasure to discover the cool work going on in our area as well as share what I’ve been up to with my lab’s new story on glycans in cancer! 🦠
Reposted by Megan Priestley
It was a pleasure to write this piece on HPV immunisation as part of our #CelebrateVaccines series 💙 Now more than ever, it is critical that we share evidence based resources on vaccination to help people make informed decisions about their health 🦠💉🌍
Cervical cancer is the 4th most common cancer in women: bit.ly/4gDCdk5.
Thanks to the HPV vaccine, that’s changing.
Find out how it has transformed cervical cancer prevention in the first blog of our #CelebrateVaccines series: bit.ly/4hXQSXF
Thanks to the HPV vaccine, that’s changing.
Find out how it has transformed cervical cancer prevention in the first blog of our #CelebrateVaccines series: bit.ly/4hXQSXF
April 2, 2025 at 1:19 PM
It was a pleasure to write this piece on HPV immunisation as part of our #CelebrateVaccines series 💙 Now more than ever, it is critical that we share evidence based resources on vaccination to help people make informed decisions about their health 🦠💉🌍
Reposted by Megan Priestley
Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age
https://go.nature.com/3Xm6v3R
https://go.nature.com/3Xm6v3R
‘Slime’ keeps the brain safe ― and could guard against ageing
Nature - Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age, studies in mice show.
go.nature.com
March 1, 2025 at 12:47 PM
Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age
https://go.nature.com/3Xm6v3R
https://go.nature.com/3Xm6v3R
Reposted by Megan Priestley
Reposted by Megan Priestley
Well done Meg! So exited for what you will do in the next few years
After a great few weeks settling into my new lab with @jcstark.bsky.social at the @mitkochinstitute.bsky.social , I’m thrilled to share I have been awarded a TBBCF postdoc fellowship! This award will fund the next 2 years of my research targeting glycans for the treatment of breast cancer 🦠
February 15, 2025 at 6:59 PM
Well done Meg! So exited for what you will do in the next few years
Reposted by Megan Priestley
Megan, our lab's first postdoc, has set a record that will be hard to beat: securing a competitive fellowship in her first week on the job! I'm grateful to TBBCF for their support and privileged to work with outstanding scientists like Megan, more on her work here: tbbcf.org/research/ Congrats! 🍾
After a great few weeks settling into my new lab with @jcstark.bsky.social at the @mitkochinstitute.bsky.social , I’m thrilled to share I have been awarded a TBBCF postdoc fellowship! This award will fund the next 2 years of my research targeting glycans for the treatment of breast cancer 🦠
February 14, 2025 at 7:48 PM
Megan, our lab's first postdoc, has set a record that will be hard to beat: securing a competitive fellowship in her first week on the job! I'm grateful to TBBCF for their support and privileged to work with outstanding scientists like Megan, more on her work here: tbbcf.org/research/ Congrats! 🍾
After a great few weeks settling into my new lab with @jcstark.bsky.social at the @mitkochinstitute.bsky.social , I’m thrilled to share I have been awarded a TBBCF postdoc fellowship! This award will fund the next 2 years of my research targeting glycans for the treatment of breast cancer 🦠
February 14, 2025 at 6:54 PM
After a great few weeks settling into my new lab with @jcstark.bsky.social at the @mitkochinstitute.bsky.social , I’m thrilled to share I have been awarded a TBBCF postdoc fellowship! This award will fund the next 2 years of my research targeting glycans for the treatment of breast cancer 🦠