Long Nguyen
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longnguyen.bsky.social
Long Nguyen
@longnguyen.bsky.social
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Physician-Scientist at MGH. Computational metagenomics, epidemiology, and other miscellany.
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Reposted by Long Nguyen
hutlab.bsky.social
Congrats to Yancong, Amrisha, Xochitl, Eric and all co-authors!!!
October 17, 2025 at 3:36 PM
Reposted by Long Nguyen
hutlab.bsky.social
Long and Kelsey just won the 2025 Microbiome SMRT Grant for HiFi shotgun metagenomics!! They will collaborate to optimize PacBio-compatible protocols for gut metagenomics, specifically generating high quality long-read data from IBD patients. Congrats to both! 🎉 🎉 www.pacb.com/blog/2025-mi...
September 17, 2025 at 6:58 PM
Reposted by Long Nguyen
pacbio.bsky.social
We’re thrilled to announce the 2025 Microbiome SMRT Grant winners! 🎉 Four researchers from around the globe will use HiFi sequencing to push the boundaries of metagenomics.

See the awardees and their projects: bit.ly/3IiBrxq

#PacBio #Microbiome #Genomics #SMRTGrant
September 12, 2025 at 7:42 PM
Reposted by Long Nguyen
fasnicar.bsky.social
🧬🖥️ Postdoc positions available SOON!!
Looking for researchers with strong computational skills (programming essential) to work on microbiome & phylogenetics projects.
📅 Start on Nov 1, 2025 (flexible)
📍 Trento, Italy
DM me for details or share!
#postdocjobs #microbiome #metagenomics #phylogenetics
July 4, 2025 at 9:11 AM
Reposted by Long Nguyen
hanseulkim.bsky.social
⚡🦠I'm very excited to share our latest work on the gut microbiome and metabolic dysfunction-associated steatotic liver disease (MASLD) is published in @natmetabolism.nature.com, with @hutlab.bsky.social & @longnguyen.bsky.social!

🔗Check out the paper here:
www.nature.com/articles/s42...
July 3, 2025 at 12:59 PM
Reposted by Long Nguyen
natmetabolism.nature.com
Multi-omic analysis reveals transkingdom gut dysbiosis in metabolic dysfunction-associated steatotic liver disease
Nature Metabolism, Published online: 02 July 2025; doi:10.1038/s42255-025-01318-6High-resolution multi-omic profiling indicates widespread gut dysbiosis in individuals with MASLD, also affecting the virome, and reveals microbial signatures that can classify MASLD and its subtypes.
bit.ly
July 3, 2025 at 12:58 AM
Reposted by Long Nguyen
natmetabolism.nature.com
Viewing MASLD through an integrative gut microbiome lens
Nature Metabolism, Published online: 02 July 2025; doi:10.1038/s42255-025-01300-2The gut microbiome is pivotal to the development of liver diseases in multifaceted ways. A recent study uses a multi-omics, multi-kingdom approach to analyse the gut dysbiosis in metabolic dysfunction-associated steatotic liver disease, highlighting a substantial role for oral-typical microorganisms and their associated metabolites.
bit.ly
July 3, 2025 at 12:58 AM
Reposted by Long Nguyen
erictopol.bsky.social
The gut microbiome signature from different diets in 20,000 individuals. Red meat intake correlated with reduced cardiometabolic health; the opposite for plant-based foods or in omnivores with enriched plant-based intake
www.nature.com/articles/s41...
January 6, 2025 at 4:07 PM
Reposted by Long Nguyen
natmicrobiol.nature.com
OUT NOW: Metagenomic immunoglobulin sequencing (MIg-seq) reveals IgA coating of microbial strains in the healthy human gut

by Justin Sonnenburg, Matt Olm, Sean Spencer & co

#microsky

www.nature.com/articles/s41...
Metagenomic immunoglobulin sequencing reveals IgA coating of microbial strains in the healthy human gut - Nature Microbiology
Metagenomic immunoglobulin sequencing (MIg-seq) uncovered patterns of IgA antibody binding of bacterial strains in the healthy human gut microbiome.
www.nature.com
January 2, 2025 at 5:38 PM
Reposted by Long Nguyen
natmicrobiol.nature.com
OUT NOW Profiling lateral gene transfer events in the human microbiome using WAAFLE

@hutlab.bsky.social @efranzosa.bsky.social @harvardchanschool.bsky.social @longnguyen.bsky.social

www.nature.com/articles/s41...
Profiling lateral gene transfer events in the human microbiome using WAAFLE - Nature Microbiology
Applying WAAFLE to metagenomic data from human samples reveals over 100,000 putative LGTs not currently found in reference genomes, highlighting an underappreciated microbiome phenomenon.
www.nature.com
January 2, 2025 at 5:29 PM
Reposted by Long Nguyen
natureportfolio.nature.com
A study in Nature of people living in 18 isolated Honduras villages shows gut microbiome strain sharing between many relationship types, including non-familial and non-household connections. Strain-sharing also extends to second-degree social connections. https://go.nature.com/4fBCp3j 🧪
This is figure 1, which shows strain-sharing across multiple relationship types.
November 28, 2024 at 4:11 PM
Reposted by Long Nguyen
Sharing a Shiny app I've been working on at
@leviwaldron1.bsky.social 's lab: BugSigDBEnrich. The app lets you compare a list of bacteria with published microbial signatures curated in bugsigdb.org.

shiny.sph.cuny.edu/BugSigDBEnri...

#rstats #microbiome #microbiomeresearch
November 28, 2024 at 2:05 AM