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PacBio
@pacbio.bsky.social
Our mission is to enable the promise of genomics to better human health by creating the world’s most advanced sequencing technologies.
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A little birdie told us we should migrate to bluer skies. 😉 Hello Bluesky world. 👋🌎 Please re-share this post so we can follow you and help to grow the genomics community on here! 🧬✨
⏰ Last chance. Entries close tomorrow!

#PacBio is giving you the chance to attend a 2026 genomics conference of your choice with flights, hotel, and registration covered up to $3,000. Meet HiFi experts and see the technology in action.

Apply by Dec 31: bit.ly/4oJQxvy
December 30, 2025 at 6:10 PM
Happy holidays! 🦌🎄

A new chromosome-level genome assembly of Norwegian wild alpine reindeer was generated using #PacBio HiFi long reads, delivering accurate, haplotype-resolved results.

See more HiFi-powered science at #PAG33 and visit us at booth 219!

Read the paper: bit.ly/3Y0tEZu
December 26, 2025 at 4:55 PM
🎶 One more holiday gift from #PacBio. Inspired by Andor and his love for albums you play start to finish.

🎁 We’re gifting a brand-new record player of your choice* to one person who signs up for the BEYOND THE BENCH series before Dec 25.

Sign up here: bit.ly/4oLrOXu
December 24, 2025 at 4:45 PM
🥾 A holiday gift from #PacBio, inspired by Birgitt. From trail snacks to essential gear, her hikes help fuel big ideas beyond the bench.

🎁 We’re gifting hiking gear of your choice* to one person who signs up for the BEYOND THE BENCH series before Dec 25.

Sign up here: bit.ly/4oLrOXu
December 23, 2025 at 4:51 PM
#PAG33 is on the horizon! 🌿🐾

Visiting the show? Stop by #PacBio booth 219 for live Vega sequencing demos and conversations on how HiFi sequencing supports large, complex plant, animal, and environmental genomics studies.

See what’s planned: bit.ly/48O6aLU
December 22, 2025 at 8:46 PM
☕ A holiday gift inspired by Santosha’s favorite coffee.

Sign up for the BEYOND THE BENCH series before Dec 25 for a chance to win a coffee subscription of your choice. We can’t wait to share the series when it premieres in January.

Start your mornings the Santosha way: bit.ly/4oLrOXu
December 22, 2025 at 5:14 PM
The 2025 #Immunology and #Immunotherapy SMRT Grant is open. Apply for a chance to advance your research with #PacBio HiFi long-read sequencing using the ProfilAIR immune repertoire assay. Three winners will receive sequencing on two Vega SMRT Cells.

Apply now: bit.ly/4pKhgIG
December 19, 2025 at 4:37 PM
You voted and the verdict is in. Everyone unwinds differently off the clock.

For the researchers in Beyond the Bench, the results varied. A crossword at dawn. A hand built turntable. Miles on a mountain trail.

Meet them in our latest blog: bit.ly/4pH7jfB

#PacBio #BeyondTheBench #Blog
Beyond the Bench: A series celebrating the people behind scientific progress - PacBio
Beyond the Bench is a PacBio original video series is focused on the people behind the science in their daily routines.
bit.ly
December 18, 2025 at 5:58 PM
Someone just won a trip to #PAG33! 👀

Meet Luke Strickland, PhD candidate at Michigan State - our first 2026 #PacBio Conference Giveaway winner.

Want to be next? 4 spots left. Entries close Dec 31.

Apply before the year’s over 👉 bit.ly/4oJQxvy
December 17, 2025 at 9:31 PM
Last call!🚨 Discover how #PacBio Iso-Seq long-read RNA sequencing is helping reveal the splicing events that shape immunotherapy responses in lung cancer. Learn how full-length transcripts uncover potential biomarkers and therapeutic targets.

Register to attend tomorrow: bit.ly/4ouCkTz
December 17, 2025 at 4:30 PM
A Nature study uses #PacBio long-read sequencing to map chromatin architecture in single cells with DAF-seq, extending Fiber-seq and showing multiomic HiFi reads capture chromatin features and sequence, revealing haplotype-specific regulatory variation across cells.

Details: go.nature.com/4pODNVl
Mapping single-cell diploid chromatin fiber architectures using DAF-seq - Nature Biotechnology
Single-molecule chromatin fiber sequencing exposes single-cell-level heterogeneity in the chromatin architecture of individual regulatory elements.
https://go.nature.com/4pODNVl"
December 16, 2025 at 9:31 PM
What’s your favorite gene? 🧬 Reply below!

Attendees at ASHG shared theirs, showing how important it is to get accurate data. Sequencing complex regions can be tricky, but HiFi long reads make it easier.

Get your free Seq 101 Guide: bit.ly/4gGkp9t

#PacBio #TheresHiFiForThat #Genomics
December 16, 2025 at 4:41 PM
PacBio is heading to #FOG2026 in London. See #Revio in action, our high-accuracy, user-friendly long-read sequencing system. Connect with our team & take part in our Magenta Moments social competition for a chance to win. 

Learn more: bit.ly/3MAm7y1
#TheresHiFiForThat
December 16, 2025 at 3:35 PM
#PAG33 is coming! 🌱🦓

See how #PacBio HiFi sequencing is helping researchers achieve more accurate and complete results in plant, animal, and microbial genomics. Discover scalable workflows and advanced insights.

Full conference details here: bit.ly/48O6aLU
December 15, 2025 at 8:38 PM
New to long read sequencing or looking for a clearer starting point?

Our Sequencing 101 blog breaks down how HiFi supports researchers at every career stage and links to the Seq 101 Guide, plus grant tips and videos delivered by email.

Read more: bit.ly/4jhUlmp

#PacBio #TheresHiFiForThat #Seq101
Sequencing 101: A long-read sequencing starter guide - PacBio
Here's a set of sequencing materials that offer clear, practical guidance for people at every career stage.
bit.ly
December 15, 2025 at 5:29 PM
Sequencing's Little Struggles:
➡️ Sequencing that’s fast
⬅️ Basecalling that… isn’t

HiFi closes the gap with sequencing and basecalling in a streamlined workflow.
No GPU pile-up or added costs you didn't expect.

Download the #PacBio Seq 101 guide to see how HiFi fits into your lab: bit.ly/4gGkp9t
December 12, 2025 at 5:03 PM
Holiday watchlist shaping up? ❄️🎄🎁

Save a spot for BEYOND THE BENCH, a #PacBio series that follows science through the people behind the discoveries. There is always more to genomics than meets the eye.

Sign up for the January premiere: bit.ly/4oLrOXu

#BeyondTheBench #PacBio #TheresHiFiForThat
December 11, 2025 at 5:44 PM
Reposted by PacBio
I am SOOO excited to welcome our brand-new VEGA instrument, made possible through a collaboration among @uv.es @i2sysbio.es and @pacbio.bsky.social . Months ago, we fantasized about having one, and now this is a reality. I can´t wait to run the many projects we have in the pipeline!
December 10, 2025 at 7:37 AM
From pipetting samples to managing data, every lab role has challenges. HiFi sequencing can make your work easier and your results more reliable.

Download the Seq 101 Guide to see how HiFi supports your lab, research, and role: bit.ly/4gGkp9t

#PacBio #ThereHiFiForThat #HiFisequencing
December 10, 2025 at 5:41 PM
This month’s Powered by PacBio features studies showing HiFi’s impact on variant detection in paralogous loci, visualizing challenging pangenome regions, uncovering SCA10 repeat patterns, and enabling a low cost CAH screening assay.

Full recap: bit.ly/4puWugK

#PacBio #HiFisequencing #RareDisease
Powered by PacBio: Selected publications from November 2025 - PacBio
November’s standout publications show how PacBio technology is impacting advances in human genomics research.
https://bit.ly/4puWugK"
December 9, 2025 at 3:05 PM
Countdown starts now.
The genomics series we’ve all been waiting for – a #PacBio original series.

Trailer’s out.
Premiere’s coming.

Add it to your watchlist 👇
🔗 bit.ly/4oLrOXu
December 4, 2025 at 6:30 PM
A big step for long read sequencing in China!

#PacBio and BaoCheng Biotechnology have opened the PacBio BaoCheng Biotech China Joint Lab in Hangzhou, featuring the #Vega HiFi system and a full sample to report workflow to support researchers across the region.
December 3, 2025 at 10:25 PM
The 2025 Immuno SMRT Grant is open! Apply for a chance to accelerate your #immunology or #immunotherapy research with PacBio #HiFisequencing through the ProfilAIR immune repertoire profiling assay. Three winners will receive sequencing on two Vega SMRT Cells.

Apply here: bit.ly/4pKhgIG

#PacBio
December 3, 2025 at 8:28 PM
Conferences like ASHG, PAG, and ESHG are key to advancing genomics. Apply for a #PacBio conference giveaway for a chance to attend a 2026 conference of your choice with travel and registration covered.

Apply here: bit.ly/4oJQxvy

#TheresHiFiForThat
December 2, 2025 at 9:27 PM
Discover how #PacBio Iso-Seq long-read RNA sequencing is helping reveal the splicing events that shape immunotherapy responses in lung cancer. Learn how full-length transcripts uncover potential biomarkers and therapeutic targets.

Register: bit.ly/4ouCkTz

#IsoSeq #CancerResearch #Immunotherapy
December 2, 2025 at 5:49 PM