Jon Mosser
@jonmosser.com
Pediatric infectious disease doc | global health researcher | modelling disease burden and intervention coverage from local to global scales | #vaccines, #VPDs, #NTDs, #malaria, #anemia, #hemoglobinopathies, #geospatial analysis | he/him | opinions my own
Pinned
Jon Mosser
@jonmosser.com
· 14d
Global, regional, and national burden of Chagas disease, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
The GBD 2023 Chagas disease estimates are notably higher than previous GBD estimates,
reflecting additional data and methodological improvements, and those published by
the Pan American Health Organiz...
www.thelancet.com
New GBD 2023 estimates of the burden of #Chagas disease, a #NTD caused by T. cruzi and transmitted by triatomine bugs, blood, or congenitally. The chronic phase, often decades after infection, causes severe heart failure, arrhythmias, and megaviscera.
#GBD2023 #ChagasDisease #NTDs #IDSky
#GBD2023 #ChagasDisease #NTDs #IDSky
Global, regional, and national burden of Chagas disease, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
The GBD 2023 Chagas disease estimates are notably higher than previous GBD estimates,
reflecting additional data and methodological improvements, and those published by
the Pan American Health Organiz...
www.thelancet.com
November 4, 2025 at 3:49 PM
Out now in @plos NTDs - overlap between #LF prevalence and #malaria ITN access / use. Congrats to Joanna Whisnant and the authorship team. This has been a long time coming and great to see it out!
#NTDs #episky #malaria #lymphaticfilariasis
#NTDs #episky #malaria #lymphaticfilariasis
Examining the overlap in lymphatic filariasis prevalence and malaria insecticide-treated net access-use in endemic Africa
Author summary Lymphatic filariasis is a vector-borne disease that can cause significant disability. There is evidence that insecticide-treated nets used by malaria programs can contribute to lymphati...
doi.org
June 28, 2025 at 12:16 PM
“In the face of demonstration that vaccines are the single most lifesaving technology for children, over half a century, he is asserting a position that the U.S. will not support vaccination. This is utterly disastrous for children around the world and for public health.”
-- @agawande.bsky.social
-- @agawande.bsky.social
Kennedy Withdraws U.S. Funding Pledge to International Vaccine Agency
www.nytimes.com
June 25, 2025 at 4:58 PM
“In the face of demonstration that vaccines are the single most lifesaving technology for children, over half a century, he is asserting a position that the U.S. will not support vaccination. This is utterly disastrous for children around the world and for public health.”
-- @agawande.bsky.social
-- @agawande.bsky.social
"Whatever progress we’ve made could be reversed if we don’t maintain and build on our successful #immunization efforts to date.” - Prof. Art Reingold, @berkeleypublichlth.bsky.social.
Read more @statnews.com
Read more @statnews.com
Vaccine hesitancy and misinformation is eroding public confidence in immunization, a new study found
www.statnews.com/2025/06/24/v...
www.statnews.com/2025/06/24/v...
Childhood vaccination coverage was falling across the globe even before Covid
Childhood vaccinations coverage slowed significantly even before the onset of the Covid-19 pandemic, a new study found.
www.statnews.com
June 25, 2025 at 4:21 PM
"Whatever progress we’ve made could be reversed if we don’t maintain and build on our successful #immunization efforts to date.” - Prof. Art Reingold, @berkeleypublichlth.bsky.social.
Read more @statnews.com
Read more @statnews.com
"Falling global #vaccine coverage, an increase in the numbers of children receiving no vaccines, and delays in vaccination mean that more children will be hospitalised, permanently damaged and die from fully preventable diseases if the trend is not reversed." - Prof. Andrew Pollard
expert reaction to study looking at global childhood vaccination coverage
www.sciencemediacentre.org/expert-react...
www.sciencemediacentre.org/expert-react...
June 25, 2025 at 2:09 AM
"Falling global #vaccine coverage, an increase in the numbers of children receiving no vaccines, and delays in vaccination mean that more children will be hospitalised, permanently damaged and die from fully preventable diseases if the trend is not reversed." - Prof. Andrew Pollard
Now out in @thelancet.com: our group's analysis of global vaccination coverage trends, the impact of the COVID pandemic, and progress towards global targets.
Congratulations to all of our co-authors - this was a massive amount of work and comes at a particularly critical time.
Highlights in 🧵
Congratulations to all of our co-authors - this was a massive amount of work and comes at a particularly critical time.
Highlights in 🧵
Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023
Our estimates of current vaccine coverage and forecasts to 2030 suggest that achieving
IA2030 targets, such as halving zero-dose children compared with 2019 levels and reaching
90% global coverage for...
www.thelancet.com
June 25, 2025 at 1:30 AM
Now out in @thelancet.com: our group's analysis of global vaccination coverage trends, the impact of the COVID pandemic, and progress towards global targets.
Congratulations to all of our co-authors - this was a massive amount of work and comes at a particularly critical time.
Highlights in 🧵
Congratulations to all of our co-authors - this was a massive amount of work and comes at a particularly critical time.
Highlights in 🧵
"The #GatesFoundation will announce ahead of the #Gavi fundraising in Brussels on Wednesday that it will match — but not go beyond — the $1.6bn it’s giving during the organisation’s current funding cycle."
Bill Gates says he will not fill vaccine funding gap left by aid cuts
Billionaire philanthropist says his foundation will maintain funding at previous levels ahead of pledging event
www.ft.com
June 24, 2025 at 8:14 PM
"The #GatesFoundation will announce ahead of the #Gavi fundraising in Brussels on Wednesday that it will match — but not go beyond — the $1.6bn it’s giving during the organisation’s current funding cycle."
Reposted by Jon Mosser
🗓️ 8 DAYS TO GO 🗓️
Every bold global health milestone began with one moment of collective will. In 8 days, world leaders will face that moment. Will they rise to protect 500 million children and build the strongest immunisation push in history?
#ForOurFuture
Every bold global health milestone began with one moment of collective will. In 8 days, world leaders will face that moment. Will they rise to protect 500 million children and build the strongest immunisation push in history?
#ForOurFuture
June 17, 2025 at 6:01 AM
🗓️ 8 DAYS TO GO 🗓️
Every bold global health milestone began with one moment of collective will. In 8 days, world leaders will face that moment. Will they rise to protect 500 million children and build the strongest immunisation push in history?
#ForOurFuture
Every bold global health milestone began with one moment of collective will. In 8 days, world leaders will face that moment. Will they rise to protect 500 million children and build the strongest immunisation push in history?
#ForOurFuture
The #Pediatric #InfectiousDisease Society has released a statement on the mass removal of all ACIP members.
"Removing vaccine experts from developing thoughtful policy will harm all Americans, particularly our children."
"Removing vaccine experts from developing thoughtful policy will harm all Americans, particularly our children."
PIDS Deeply Troubled By Disregard for Science in ACIP Firings – Pediatric Infectious Diseases Society
pids.org
June 10, 2025 at 2:54 PM
The #Pediatric #InfectiousDisease Society has released a statement on the mass removal of all ACIP members.
"Removing vaccine experts from developing thoughtful policy will harm all Americans, particularly our children."
"Removing vaccine experts from developing thoughtful policy will harm all Americans, particularly our children."
Reposted by Jon Mosser
This week, as the number of confirmed measles cases rose to 483, the CDC buried a report that would’ve stressed the importance of getting vaccinated.
The move was “not normal at all,” one agency staff member said.
By @sheinvestigates.bsky.social
The move was “not normal at all,” one agency staff member said.
By @sheinvestigates.bsky.social
The CDC Buried a Measles Forecast That Stressed the Need for Vaccinations
The move — along with the CDC’s explanation — is a sign that the nation’s top public health agency may be falling in line under HHS Secretary Robert F. Kennedy Jr., a longtime critic of vaccines.
propub.li
March 30, 2025 at 3:00 AM
This week, as the number of confirmed measles cases rose to 483, the CDC buried a report that would’ve stressed the importance of getting vaccinated.
The move was “not normal at all,” one agency staff member said.
By @sheinvestigates.bsky.social
The move was “not normal at all,” one agency staff member said.
By @sheinvestigates.bsky.social
The HHS investigation into the long-debunked #measles #vaccine / autism (non-)connection continues to ramp up.
“To me, the big shame is that with budget cuts, we are not ramping up research into what is actually causing autism,” Mr. Hunter said.
#idsky #pedsidsky #episky
“To me, the big shame is that with budget cuts, we are not ramping up research into what is actually causing autism,” Mr. Hunter said.
#idsky #pedsidsky #episky
RFK Jr. Turns to a Discredited Vaccine Researcher for Autism Study
David Geier has been hired as a senior data analyst at H.H.S. According to several people, he will examine any potential links between vaccines and autism that were debunked long ago.
www.nytimes.com
March 27, 2025 at 10:59 PM
The HHS investigation into the long-debunked #measles #vaccine / autism (non-)connection continues to ramp up.
“To me, the big shame is that with budget cuts, we are not ramping up research into what is actually causing autism,” Mr. Hunter said.
#idsky #pedsidsky #episky
“To me, the big shame is that with budget cuts, we are not ramping up research into what is actually causing autism,” Mr. Hunter said.
#idsky #pedsidsky #episky
@nature.com just published a list of "research activities that NIH no longer supports", including studies on #vaccine hesitancy, #climatechange, #DEI, " #transgender issues", China, and South Africa.
#episky #medsky #idsky #pedsidsky
#episky #medsky #idsky #pedsidsky
Exclusive: NIH to cut grants for COVID research, documents reveal
Studies on climate change and South Africa are also on the latest list of grants to be terminated, according to updated documents obtained by Nature.
www.nature.com
March 26, 2025 at 9:12 PM
@nature.com just published a list of "research activities that NIH no longer supports", including studies on #vaccine hesitancy, #climatechange, #DEI, " #transgender issues", China, and South Africa.
#episky #medsky #idsky #pedsidsky
#episky #medsky #idsky #pedsidsky
The US government is stopping support for Gavi, which plays a massive role in providing #vaccines to children around the world.
The US provides 13% of Gavi's budget.
#episky #idsky #pedsidsky
The US provides 13% of Gavi's budget.
#episky #idsky #pedsidsky
U.S. to End Vaccine Funds for Poor Countries
A 281-page spreadsheet obtained by The Times lists the Trump administration’s plans for thousands of foreign aid programs.
www.nytimes.com
March 26, 2025 at 3:26 PM
The US government is stopping support for Gavi, which plays a massive role in providing #vaccines to children around the world.
The US provides 13% of Gavi's budget.
#episky #idsky #pedsidsky
The US provides 13% of Gavi's budget.
#episky #idsky #pedsidsky
Reposted by Jon Mosser
Despite a substantial decrease in solid fuel use for cooking worldwide, exposure to household air pollution (HAP) remains a major global risk factor.
A #GBD study calls for renewed efforts & international investments to reduce the burden of HAP: tinyurl.com/3w94ysy9 @ihmeuw.bsky.social
A #GBD study calls for renewed efforts & international investments to reduce the burden of HAP: tinyurl.com/3w94ysy9 @ihmeuw.bsky.social
March 20, 2025 at 2:12 PM
Despite a substantial decrease in solid fuel use for cooking worldwide, exposure to household air pollution (HAP) remains a major global risk factor.
A #GBD study calls for renewed efforts & international investments to reduce the burden of HAP: tinyurl.com/3w94ysy9 @ihmeuw.bsky.social
A #GBD study calls for renewed efforts & international investments to reduce the burden of HAP: tinyurl.com/3w94ysy9 @ihmeuw.bsky.social
Reposted by Jon Mosser
MMR vaccines do not cause autism—the evidence is overwhelming.
I teamed up with @unbiasedscipod.bsky.social to break down decades of research, covering dozens of studies with millions of children.
open.substack.com/pub/theunbia...
I teamed up with @unbiasedscipod.bsky.social to break down decades of research, covering dozens of studies with millions of children.
open.substack.com/pub/theunbia...
A Comprehensive Review of the MMR Vaccine Studies: Many Years and Millions of People Reveal NO Link to Autism
Time to Move Forward: What Decades of Consistent Evidence Should Tell Us
open.substack.com
March 20, 2025 at 2:04 AM
MMR vaccines do not cause autism—the evidence is overwhelming.
I teamed up with @unbiasedscipod.bsky.social to break down decades of research, covering dozens of studies with millions of children.
open.substack.com/pub/theunbia...
I teamed up with @unbiasedscipod.bsky.social to break down decades of research, covering dozens of studies with millions of children.
open.substack.com/pub/theunbia...
Reposted by Jon Mosser
During the worst measles outbreak in DECADES, we ABSOLUTELY must invest funding, time, & energy toward understanding why some Americans are hesitant to get the vaccines they need.
We want people to get vaccinated so they don't die. It makes NO sense to eliminate this research.
We want people to get vaccinated so they don't die. It makes NO sense to eliminate this research.
NIH to terminate or limit grants related to vaccine hesitancy and uptake
The order covers more than 40 awards to researchers around the country seeking to understand why vaccine acceptance has declined.
www.washingtonpost.com
March 11, 2025 at 12:46 AM
During the worst measles outbreak in DECADES, we ABSOLUTELY must invest funding, time, & energy toward understanding why some Americans are hesitant to get the vaccines they need.
We want people to get vaccinated so they don't die. It makes NO sense to eliminate this research.
We want people to get vaccinated so they don't die. It makes NO sense to eliminate this research.
"Mr. Kennedy said [HHS] would conduct clinical trials on several unproven treatments for measles, including a steroid, budesonide; an antibiotic called clarithromycin; and cod liver oil".
I'm sorry - exactly how many cases of #measles are we planning to have in the USA, if we're funding RCTs now?
I'm sorry - exactly how many cases of #measles are we planning to have in the USA, if we're funding RCTs now?
Kennedy Links Measles Outbreak to Poor Diet and Health, Citing Fringe Theories
In a recent interview, the health secretary also suggested that the measles vaccine had harmed children in West Texas, center of an outbreak.
www.nytimes.com
March 11, 2025 at 12:25 AM
"Mr. Kennedy said [HHS] would conduct clinical trials on several unproven treatments for measles, including a steroid, budesonide; an antibiotic called clarithromycin; and cod liver oil".
I'm sorry - exactly how many cases of #measles are we planning to have in the USA, if we're funding RCTs now?
I'm sorry - exactly how many cases of #measles are we planning to have in the USA, if we're funding RCTs now?
I can't even with this.
Effective interventions to keep kids from dying of measles:
1. The measles vaccine
2. The measles vaccine
3. The measles vaccine
4. The measles vaccine
...
10. Good supportive care; vitamin A treatment.
(Not listed: cod liver oil)
#idsky #pedsidsky #pedssky
Effective interventions to keep kids from dying of measles:
1. The measles vaccine
2. The measles vaccine
3. The measles vaccine
4. The measles vaccine
...
10. Good supportive care; vitamin A treatment.
(Not listed: cod liver oil)
#idsky #pedsidsky #pedssky
As Measles Spreads, Kennedy Embraces Remedies Like Cod Liver Oil
In an interview, the H.H.S. secretary claimed that unconventional treatments were helping patients but did not mention vaccination.
www.nytimes.com
March 5, 2025 at 7:05 AM
I can't even with this.
Effective interventions to keep kids from dying of measles:
1. The measles vaccine
2. The measles vaccine
3. The measles vaccine
4. The measles vaccine
...
10. Good supportive care; vitamin A treatment.
(Not listed: cod liver oil)
#idsky #pedsidsky #pedssky
Effective interventions to keep kids from dying of measles:
1. The measles vaccine
2. The measles vaccine
3. The measles vaccine
4. The measles vaccine
...
10. Good supportive care; vitamin A treatment.
(Not listed: cod liver oil)
#idsky #pedsidsky #pedssky
Reposted by Jon Mosser
Measles, even in a reasonably vaccinated population, can spread among the unvaccinated about as fast as COVID-19 spread in the beginning of 2020.
That was fast enough for us to be concerned in 2020. It's fast enough for us to be concerned in 2025.
That was fast enough for us to be concerned in 2020. It's fast enough for us to be concerned in 2025.
Vaccination eliminated measles from the U.S. 25 years ago. But it can still spread in pockets where vaccination rates are low, like the west Texas county with a current outbreak. Here's how fast.
As the Texas outbreak grows, how contagious is measles, really?
Vaccination eliminated measles from the U.S. 25 years ago. But it can still spread in pockets where vaccination rates are low, like the west Texas county with a current outbreak. Here's how fast.
www.npr.org
February 28, 2025 at 8:25 PM
Measles, even in a reasonably vaccinated population, can spread among the unvaccinated about as fast as COVID-19 spread in the beginning of 2020.
That was fast enough for us to be concerned in 2020. It's fast enough for us to be concerned in 2025.
That was fast enough for us to be concerned in 2020. It's fast enough for us to be concerned in 2025.
Reposted by Jon Mosser
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration.
blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org/hiv-id-obser...
Tragic Childhood Death from Measles Reminds Us That Some Don't Understand Either the Medical Significance or the Human Heart
My ID colleague Dr. Adam Ratner, Chief of Pediatric ID at NYU Medical Center, just published an insightful and remarkably timely book called Booster Shots: The Urgent Lessons of Measles and the Uncer...
blogs.jwatch.org
February 27, 2025 at 9:14 PM
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration.
blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org/hiv-id-obser...
Absolute, unspeakable cruelty.
“People will die,” said Dr. Catherine Kyobutungi, executive director of the African Population and Health Research Center, “but we will never know, because even the programs to count the dead are cut.”
#episky #medsky
“People will die,” said Dr. Catherine Kyobutungi, executive director of the African Population and Health Research Center, “but we will never know, because even the programs to count the dead are cut.”
#episky #medsky
U.S. Terminates Funding for Polio, H.I.V., Malaria and Nutrition Programs Around the World
Here are some of the 5,800 contracts the Trump administration formally canceled this week in a wave of terse emails.
www.nytimes.com
February 28, 2025 at 2:47 AM
It's difficult to overstate what we're losing with the end of the DHS program.
These surveys anchor our understanding of health around the world, especially in places where good data are missing and where global inequities in health are most acute.
What a catastrophic, short-sighted decision.
These surveys anchor our understanding of health around the world, especially in places where good data are missing and where global inequities in health are most acute.
What a catastrophic, short-sighted decision.
Trump Administration Ends Global Health Research Program
The Demographic and Health Surveys were the only sources of reliable information in many countries on metrics such as mortality, nutrition and education.
buff.ly
February 27, 2025 at 6:31 PM
It's difficult to overstate what we're losing with the end of the DHS program.
These surveys anchor our understanding of health around the world, especially in places where good data are missing and where global inequities in health are most acute.
What a catastrophic, short-sighted decision.
These surveys anchor our understanding of health around the world, especially in places where good data are missing and where global inequities in health are most acute.
What a catastrophic, short-sighted decision.
Reposted by Jon Mosser
This news truly breaks my heart.
We are calling on HHS to take immediate action. Secretary Kennedy needs to bring back weekly measles tracking from the CDC, rehire the health experts, and roll out a serious vaccine campaign. Our kids' safety is on the line!
abcnews.go.com/Health/1st-m...
We are calling on HHS to take immediate action. Secretary Kennedy needs to bring back weekly measles tracking from the CDC, rehire the health experts, and roll out a serious vaccine campaign. Our kids' safety is on the line!
abcnews.go.com/Health/1st-m...
Measles death of unvaccinated child in Texas outbreak is 1st fatality in US in a decade
An unvaccinated school-aged child in Texas has died of measles, the first associated with an outbreak that has infected more than 100 people.
abcnews.go.com
February 27, 2025 at 1:58 AM
This news truly breaks my heart.
We are calling on HHS to take immediate action. Secretary Kennedy needs to bring back weekly measles tracking from the CDC, rehire the health experts, and roll out a serious vaccine campaign. Our kids' safety is on the line!
abcnews.go.com/Health/1st-m...
We are calling on HHS to take immediate action. Secretary Kennedy needs to bring back weekly measles tracking from the CDC, rehire the health experts, and roll out a serious vaccine campaign. Our kids' safety is on the line!
abcnews.go.com/Health/1st-m...