Jon Mosser
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jonmosser.com
Jon Mosser
@jonmosser.com
Pediatric infectious disease doc | global health researcher | modelling disease burden and intervention coverage from local to global scales | #vaccines, #VPDs, #NTDs, #malaria, #anemia, #hemoglobinopathies, #geospatial analysis | he/him | opinions my own
@who.int just released the results of a rapid pulse-taking survey on the impact of cuts to official development assistance (ODA).

More than 40-50% of countries already reporting moderate-severe service disruptions to #HIV, #TB, #Malaria, #vaccine programs.

#episky #idsky
April 11, 2025 at 6:05 PM
Here's the vaccine hesitancy language...

"It is the policy of NIH not to prioritize research activities that focuses [sic] gaining scientific knowledge on why individuals are hesitant to be vaccinated and/or explore ways to improve vaccine interest and commitment."
March 26, 2025 at 9:15 PM
#measles #vaccines have saved more than 93 million lives in the last 50 years, 68% of all the lives saved by vaccines around the world over that time.

Responsible public health messaging right now would start and end with this:

Measles vaccines save lives.

doi.org/10.1016/S014...
March 5, 2025 at 7:14 AM
This tool shows us that the #ACIP recommendations page on the #CDC website has had the definition of "Persons at Risk" scrubbed from the #mpox #vaccine recommendations.

This censorship harms patients and keeps providers from making informed recommendations.

Unfortunately, expect more to come.
February 20, 2025 at 9:49 PM
By phone: You can call the U.S. Capitol Switchboard at (202) 224-3121 or your senators' official .gov websites will have their DC office phone numbers.

The AAP has provided these sample talking points to get you started:
January 28, 2025 at 4:45 AM
1) Go to federaladvocacy.aap.org and send a letter. I did this today. It's incredibly easy.

Log in with your AAP username; the senators are pre-selected for you and an email with talking points is pre-populated for you to personalize.
January 28, 2025 at 4:41 AM
Come join our team at #IHME at the University of Washington!

We've just posted three new job openings; all will focus on disease burden estimation for #NTDs. More details in each of the job descriptions linked below.

#Episky #IDsky #globalhealth
January 8, 2025 at 4:28 PM
For more than three millennia, #smallpox caused untold human suffering.

This photo shows a young girl with smallpox in 1973 in Bangladesh. Only 7 years later, in 1980, WHO declared that smallpox had been eradicated.

No one has to experience this ever again.

All thanks to #vaccines.

#idsky
December 17, 2024 at 4:45 AM
Last, we can look at the % change in the number of positions offered, # of positions filled, and # of applicants preferring each subspecialty between 2022 and 2024! Good news for #PedsIDSky here: we have a pretty large % increase in the absolute # of applicants preferring ID! (caveat: small #s)
December 14, 2024 at 12:55 AM
As @inditrehan.bsky.social had pointed out, though, this is due to changes in both the # of positions available and # of applicants matching. For ID, for instance, both # of positions filled & # of positions available are up. For several others, ⬆️positions and ⬇️applicants are playing a role.
December 14, 2024 at 12:52 AM
Going back to the #Pediatric subspecialty match data for a bit of a deeper dive: I pulled data from 2022-2024, which is all that I could readily find on the NRMP website.

Here are the trends in the % of positions filled, by year and pediatric subspecialty. ID is pretty flat!

#Pedsky #PedsIDSky
December 14, 2024 at 12:49 AM
The President-elect of the United States of America is apparently considering vaccine bans for children based on the nonsense conspiracy theory that MMR causes autism.

It's hard to overstate what a public health catastrophe this would be.

#pedsky #pedsidsky #idsky
December 13, 2024 at 6:38 AM
This is not a typical randomized controlled trial, but rather a cluster-randomized stepped wedge design. That means that early in the study, more wards would be in the no-screening group, and later in the study, more wards would be in the screening group.
December 11, 2024 at 4:01 PM
More recently, Freed and Wickham looked at these net present value calculations and how they differ for #pediatric subspecialties by data source (AAAP vs AAMC). While the numbers and rankings are a bit different, it's hard not to see a persistent relationship with these match results.
tiny.cc/k44zzz
December 4, 2024 at 8:53 PM
Catenaccio, Rochlin, and Simon looked at the correlation between fellowship fill rates (2014-2018) and lifetime net present value (2018-2019), by pediatric subspecialty. pmc.ncbi.nlm.nih.gov/articles/PMC...
December 4, 2024 at 8:46 PM
16 measles outbreaks in 2024 so far, with 280 cases. Higher than recent years, but not as high as 2019, which was a particularly bad year for measles in the USA and around the world.

www.cdc.gov/measles/data...
December 2, 2024 at 5:59 PM
In 14/50 health jurisdictions, there were enough exemptions in 2023-2024 to make it impossible to achieve 95% coverage with the #MMR #vaccine, even if every child without an exemption were vaccinated.

This number has been on the rise over the last few years.

#IDsky #PedsIDSky #Episky #Pedsky
December 2, 2024 at 8:42 AM
This isn't even the worst of it. #Vaccine exemption rates for kindergarteners increased in 41 of 50 jurisdictions with data last year - mostly nonmedical.

In Idaho, **14.3%** of kindergarten students had exemptions (!)

tiny.cc/dcjyzz
December 2, 2024 at 8:35 AM
One last "fun" fact: the first #anti-vax movements started essentially immediately after the discovery of #vaccination. In this 1802 cartoon, the vaccine turns people into bovine abominations, with cows growing out of their heads. (This cartoon was largely a parody of extreme #anti-vaccine views).
November 28, 2024 at 7:26 PM
From those beginnings came humanity's greatest public health accomplishment: the eradication of smallpox by 1980, thanks to the power of #vaccines.
November 28, 2024 at 7:25 PM
It wasn't until 20 years later that Edward Jenner began his experiments with #smallpox #vaccination, culminating in the vaccination of 8-year-old James Phipps, the son of his gardener in 1796. He then exposed Phipps to smallpox material to test the immunity. (This is why we have IRBs).
November 28, 2024 at 7:23 PM
People then started to experiment with the use of cowpox. There were likely five or six different examples of these first #vaccinations, throughout Europe. Perhaps most well known is Benjamin Jesty, who infected his wife and kids (!) with cowpox in 1774 amidst a smallpox outbreak.
November 28, 2024 at 7:22 PM
In southwest England, amongst the dairy farming communities, people had noticed that dairymaids who contracted cowpox seemed to be immune to smallpox. In 1765, John Fewster brought this folk knowledge to the medical establishment, presenting a paper to the Medical Society of London on the topic.
November 28, 2024 at 7:22 PM
The practice of variolation was then introduced to England by Lady Mary Wortley Montagu, who witnessed it in Turkey. Her brother had died of smallpox in 1713, and she survived the disease in 1715.
November 28, 2024 at 7:21 PM
And here's the figure that shows data from three linkage studies looking at the incidence of #cervicalcancer by #vaccination status. For cohorts vaccinated early (i.e. prior to HPV infection) the reductions are really massive.
November 28, 2024 at 3:39 PM