Jan Radford
janradford.bsky.social
Jan Radford
@janradford.bsky.social
Rural GP academic based in Lutruwita (Tasmania). Humanist. UTAS. General Practice. Family Medicine. Clinical research. Medical Education. Primary care.
Reposted by Jan Radford
Imagine eliminating a cancer!!

It’s possible 👇🏾
who.int WHO @who.int · 18h
#CervicalCancer could be the first cancer EVER in the world to be eliminated, if:

9️⃣0️⃣% of girls are vaccinated
7️⃣0️⃣% of women are screened
9️⃣0️⃣% of women with cervical cancer receive treatment

Learn more: bit.ly/47GIbzd #EndCervicalCancer
November 23, 2025 at 10:01 AM
Reposted by Jan Radford
Medic student advice update.

2015.
"Do not use Wikipedia as the main source of information for your essay."

2024.
"Do not use ChatGPT as the main source of information for your essay."

2025.
"Do not use the CDC website as the main source of information for your essay."
CDC website altered to reflect RFK Jr’s belief in link between vaccines and autism
Public health and autism specialists roundly condemn alteration to the ‘vaccine safety’ webpage
www.theguardian.com
November 21, 2025 at 5:02 PM
Reposted by Jan Radford
We’re five years into the pandemic, and the science is telling a very different story than “just a cold.” COVID affects blood vessels, organs, metabolism, and cognition — and the impacts compound with each infection.
November 14, 2025 at 7:38 PM
Reposted by Jan Radford
I've been working with Dr Tamara Franz-Odendaal & Dr Karen Pinder for the AAA, to create accompanying histology images for the wonderful illustrations of Dr Mikaela Stiver in their Histology Coloring Book. This is an open resource. histologycoloringbook.com Please share.
November 8, 2025 at 1:13 AM
Adult ADHD is diagnosed when you are ‘functionally impaired’. But what does that mean?
theconversation.com/adult-adhd-i...
Adult ADHD is diagnosed when you are ‘functionally impaired’. But what does that mean?
It’s about how ADHD symptoms impact on your day-to-day functioning. Here’s how clinicians assess this, and where people might struggle.
theconversation.com
November 3, 2025 at 7:01 PM
Reposted by Jan Radford
Calling all researchers and educators📣 This new RMR by @trishgreenhalgh.bsky.social on how to conduct effective case studies, offers guidance for using them for learning & decision-making.

Essential reading for robust research!

https://bit.ly/47PL01l
September 24, 2025 at 3:49 PM
Reposted by Jan Radford
New research featuring DCRI’s Stephen Greene assessed the effects of GLP-1RAs on heart failure hospitalization and cardiovascular death across populations with varying type and number of CKM comorbidity, finding the treatment helped reduce deaths. Read more: onlinelibrary.wiley.com/doi/10.1002/...
September 22, 2025 at 5:00 PM
Reposted by Jan Radford
Ancient hybridization underlies tuberization and radiation of the potato lineage
Ancient hybridization underlies tuberization and radiation of the potato lineage
"Interspecific hybridization may trigger species radiation by creating allele combinations and traits. Cultivated potato and its 107 wild relatives from the Petota lineage all share the distinctive trait of underground tubers, but the underlying mechanisms for tuberization and its relationship to extensive species diversification remain unclear. Through analyses of 128 genomes, including 88 haplotype-resolved genomes, we revealed that Petota is of ancient hybrid origin, with all members exhibiting stable mixed genomic ancestry, derived from the Etuberosum and Tomato lineages ca. 8-9 million years ago. Our functional experiments further validated the crucial roles of parental genes in tuberization, indicating that interspecific hybridization is a key driver of this innovative trait. This trait, along with the sorting and recombination of hybridization-derived polymorphisms, likely triggered the explosive species diversification of Petota by enabling occupation of broader ecological niches. These findings highlight how ancient hybridization fosters key innovation and drives subsequent species radiation."
pubmed.ncbi.nlm.nih.gov
September 19, 2025 at 3:50 PM
A great study of over 160,000 Melbourne pregnancies to show how your postcode affects you and your baby
theconversation.com/we-studied-o...
We studied over 160,000 pregnancies to show how your postcode affects you and your baby
New research shows fast-food outlets and with few healthy food options was strongly linked to indicators of poorer health for both mother and baby.
theconversation.com
September 17, 2025 at 8:53 PM
Reposted by Jan Radford
#Medsky🧪 #Cardiosky #pharmsky #publichealth
#SGLT2 inhibitors alleviate inflammation-induced functional #irondeficiency by suppressing hepcidin & mobilizing iron stores, thereby enhancing iron availability for erythropoiesis and tissue function.
Mechanisms of enhanced renal and hepatic erythropoietin synthesis by sodium–glucose cotransporter 2 inhibitors
Abstract. Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of major heart failure events, an action that is statistically linked to enhanc
academic.oup.com
September 15, 2025 at 7:06 AM
Reposted by Jan Radford
National Climate Change Risk Assessment out now 👇🏽

Risk to current ecosystems VERY HIGH. Rick by 2050 VERY HIGH to SEVERE
September 15, 2025 at 12:45 AM
Our antibiotic stewardship in Australian #generalpractice co-design phase paper is out. www.mdpi.com/3493602
www.mdpi.com
September 11, 2025 at 8:51 PM
Reposted by Jan Radford
"This study suggests that ApoB is a more accurate marker for cardiovascular risk than LDL-P when discordant, as marked by ApoB levels in excess of LDL-P." Analysis of UK Biobank data by Elizabeth Epstein, et al. #cardiosky pubmed.ncbi.nlm.nih.gov/40887080/
Apolipoprotein B outperforms low density lipoprotein particle number as a marker of cardiovascular risk in the UK Biobank - PubMed
This study suggests that ApoB is a more accurate marker for cardiovascular risk than LDL-P when discordant, as marked by ApoB levels in excess of LDL-P. Notably, risk was already elevated at as little...
pubmed.ncbi.nlm.nih.gov
September 2, 2025 at 7:02 PM
Reposted by Jan Radford
From @jamanetworkopen.com: Despite advances in trial design, women are underrepresented in cardiovascular research, especially for high-risk conditions like arrhythmias, coronary heart disease, and acute coronary syndrome.

#ESCCongress #WCCardio

ja.ma/45TKJYw
August 31, 2025 at 1:45 PM
Reposted by Jan Radford
@jama.com: Among patients w/ NSTEMI and multivessel disease, FFR-guided complete revascularization reduced risk of death, nonfatal myocardial infarction, revascularization, and stroke at 1 year compared with culprit-only revascularization.

#ESCCongress #WCCardio

ja.ma/3VqoBQB
August 31, 2025 at 3:45 PM
Reposted by Jan Radford
Editorial: Discontinuing anticoagulation therapy after AF ablation may be beneficial for patients at intermediate stroke risk and high bleeding risk, although careful monitoring and shared decision-making are essential.

#ESCCongress #WCCardio

ja.ma/4n8N8Wq
August 31, 2025 at 3:35 PM
Reposted by Jan Radford
From @jama.com: In patients w cardiometabolic #HFpEF, #semaglutide and #tirzepatide reduced the risk of hospitalization for heart failure or all-cause mortality vs sitagliptin, but tirzepatide offered no additional benefit over semaglutide.

#ESCCongress #WCCardio

ja.ma/4nbWuRk
August 31, 2025 at 1:30 PM
Reposted by Jan Radford
Strep ❤️

Viridans streptococci DNA found in ~42% of coronary plaques, forming biofilms ignored by macrophages

Once fragments escape, TLR2 senses them—potentially triggering an inflammatory response that disrupts plaque stability and increases heart attack risk

www.ahajournals.org/doi/10.1161/...
August 30, 2025 at 9:36 PM
Reposted by Jan Radford
he more data for an individual, the better we are getting for accurate prediction of risk for Alzheimer's and Parkinson's diseases, adding layers related to the gut-brain axis
science.org/doi/full/10....
Gut-brain nexus: Mapping multimodal links to neurodegeneration at biobank scale
Co-occurring disorders of the gut-brain axis combined with genetic and proteomic data can better predict neurodegenerative risk.
science.org
August 27, 2025 at 6:10 PM