Itamar
@itamarb.bsky.social
Computational biology, cancer Immunology, target discovery, data science, soft matter physics
December 2, 2025 at 7:11 PM
Reposted by Itamar
I want one of these :)
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Biological Laboratory | LEGO® Ideas
This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…
beta.ideas.lego.com
October 17, 2025 at 4:02 AM
I want one of these :)
Reposted by Itamar
It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers.
October 15, 2025 at 12:22 PM
It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers.
Reposted by Itamar
Reposted by Itamar
1/ Our paper “Protein Language Models Expose Viral Immune Mimicry” is now published in Viruses!
We show that protein Language Models can identify viral proteins, and those that fool our immune system.
DOI: 10.3390/v17091199.
We show that protein Language Models can identify viral proteins, and those that fool our immune system.
DOI: 10.3390/v17091199.
www.mdpi.com
September 1, 2025 at 11:19 AM
1/ Our paper “Protein Language Models Expose Viral Immune Mimicry” is now published in Viruses!
We show that protein Language Models can identify viral proteins, and those that fool our immune system.
DOI: 10.3390/v17091199.
We show that protein Language Models can identify viral proteins, and those that fool our immune system.
DOI: 10.3390/v17091199.
אני לא אוהב הרצאות שהן טיזר למאמרים בלי לתאר או להסביר אותן
בכנס של יום אחד אחרי שלא הייתי בכנס כמה שנים. האמת שהתגעגעתי.
אני גם נהנה וגם מסתגל לקראת כנס ארוך יותר בקיץ
אני גם נהנה וגם מסתגל לקראת כנס ארוך יותר בקיץ
April 23, 2025 at 9:05 AM
אני לא אוהב הרצאות שהן טיזר למאמרים בלי לתאר או להסביר אותן
בכנס של יום אחד אחרי שלא הייתי בכנס כמה שנים. האמת שהתגעגעתי.
אני גם נהנה וגם מסתגל לקראת כנס ארוך יותר בקיץ
אני גם נהנה וגם מסתגל לקראת כנס ארוך יותר בקיץ
April 23, 2025 at 9:04 AM
בכנס של יום אחד אחרי שלא הייתי בכנס כמה שנים. האמת שהתגעגעתי.
אני גם נהנה וגם מסתגל לקראת כנס ארוך יותר בקיץ
אני גם נהנה וגם מסתגל לקראת כנס ארוך יותר בקיץ
Reposted by Itamar
Some science today: I had an opportunity to evaluate OpenAI's "Deep Research" software, so I asked it to summarize the toxicity of thalidomide, with respect to species differences and compound isomers. The results were superficially impressive, but concealed deeper problems:
An Evaluation of
www.science.org
February 6, 2025 at 4:36 PM
Some science today: I had an opportunity to evaluate OpenAI's "Deep Research" software, so I asked it to summarize the toxicity of thalidomide, with respect to species differences and compound isomers. The results were superficially impressive, but concealed deeper problems:
Reposted by Itamar
Online now: Online now: Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
Existing cancer immunotherapy target discovery platforms typically focus on a single cell type. Luo et al. develop ICRAFT, an interactive platform that integrates CRISPR screens and transcriptomic datasets to identify immunomodulatory gene targets across…
dlvr.it
February 28, 2025 at 11:39 PM
Online now: Online now: Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
Reposted by Itamar
So has anyone put a really, truly, AI-from-scratch antibody into the clinic yet? Press releases aside, the answer is “absolutely not”.
AI Antibodies? Really?
www.science.org
February 13, 2025 at 7:25 PM
So has anyone put a really, truly, AI-from-scratch antibody into the clinic yet? Press releases aside, the answer is “absolutely not”.
Reposted by Itamar
Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed
I’m very scared to see what happens to PubMed
January 31, 2025 at 8:44 PM
Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed
Reposted by Itamar
Announcing the new bioRxiv dashboard widget - it's now easier to when articles have comments, peer reviews, community discussion, media coverage, videos, and automated analyses 1/2 connect.biorxiv.org/news/2025/01...
January 18, 2025 at 1:55 PM
Announcing the new bioRxiv dashboard widget - it's now easier to when articles have comments, peer reviews, community discussion, media coverage, videos, and automated analyses 1/2 connect.biorxiv.org/news/2025/01...
Reposted by Itamar
1/7 I’m excited to share our paper, describing the majority of my PhD, now published in
@naturecomms.bsky.social
!
We present how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response in human cells. A 🧵
www.nature.com/articles/s41...
@naturecomms.bsky.social
!
We present how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response in human cells. A 🧵
www.nature.com/articles/s41...
January 12, 2025 at 3:52 PM
1/7 I’m excited to share our paper, describing the majority of my PhD, now published in
@naturecomms.bsky.social
!
We present how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response in human cells. A 🧵
www.nature.com/articles/s41...
@naturecomms.bsky.social
!
We present how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response in human cells. A 🧵
www.nature.com/articles/s41...
Reposted by Itamar
1/ To answer if AI has changed drug development, we first need to understand the process. Here's a quick summary:
• Target identification
• Target pharmacology & biomarker development
• Lead identification & optimization
• Target identification
• Target pharmacology & biomarker development
• Lead identification & optimization
January 7, 2025 at 2:15 PM
1/ To answer if AI has changed drug development, we first need to understand the process. Here's a quick summary:
• Target identification
• Target pharmacology & biomarker development
• Lead identification & optimization
• Target identification
• Target pharmacology & biomarker development
• Lead identification & optimization
Reposted by Itamar
Hi Science Community!
We made a starter pack of research software (& research software developers). Please make suggestions & re-post.
If you are a developer & want to be added,
please reply, link to your software,
& mention the discipline(s) it caters to.
🧪 📊 #PsychSciSky
go.bsky.app/3brP43N
We made a starter pack of research software (& research software developers). Please make suggestions & re-post.
If you are a developer & want to be added,
please reply, link to your software,
& mention the discipline(s) it caters to.
🧪 📊 #PsychSciSky
go.bsky.app/3brP43N
November 17, 2024 at 7:12 PM
Hi Science Community!
We made a starter pack of research software (& research software developers). Please make suggestions & re-post.
If you are a developer & want to be added,
please reply, link to your software,
& mention the discipline(s) it caters to.
🧪 📊 #PsychSciSky
go.bsky.app/3brP43N
We made a starter pack of research software (& research software developers). Please make suggestions & re-post.
If you are a developer & want to be added,
please reply, link to your software,
& mention the discipline(s) it caters to.
🧪 📊 #PsychSciSky
go.bsky.app/3brP43N
Reposted by Itamar
Inspired by the other amazing starter packs - here's one for cancer researchers!
I tried to make this broad - from immunology to genomics to cell biology and so much more..
This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺
Hope its useful!
go.bsky.app/FEoaJMc
I tried to make this broad - from immunology to genomics to cell biology and so much more..
This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺
Hope its useful!
go.bsky.app/FEoaJMc
November 14, 2024 at 9:44 PM
Inspired by the other amazing starter packs - here's one for cancer researchers!
I tried to make this broad - from immunology to genomics to cell biology and so much more..
This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺
Hope its useful!
go.bsky.app/FEoaJMc
I tried to make this broad - from immunology to genomics to cell biology and so much more..
This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺
Hope its useful!
go.bsky.app/FEoaJMc
Reposted by Itamar
שועל להחמדת הפיד
November 10, 2024 at 6:11 PM
שועל להחמדת הפיד
Reposted by Itamar
per @igorulitsky.bsky.social 's suggestion, I made an Israeli biologists starter pack.
It's very thin...
If I missed you (or someone you know that should be there) - let me know and I'll add you/they.
go.bsky.app/5Vt5bP7
It's very thin...
If I missed you (or someone you know that should be there) - let me know and I'll add you/they.
go.bsky.app/5Vt5bP7
November 10, 2024 at 4:47 PM
per @igorulitsky.bsky.social 's suggestion, I made an Israeli biologists starter pack.
It's very thin...
If I missed you (or someone you know that should be there) - let me know and I'll add you/they.
go.bsky.app/5Vt5bP7
It's very thin...
If I missed you (or someone you know that should be there) - let me know and I'll add you/they.
go.bsky.app/5Vt5bP7
Reposted by Itamar
Here's a paper that explains the difference between standard errors and standard deviations:
bmj.com/content/331/...
Here's our paper, which shows that experts (doctors, professors, data scientists) mix them up:
www.pnas.org/doi/10.1073/...
bmj.com/content/331/...
Here's our paper, which shows that experts (doctors, professors, data scientists) mix them up:
www.pnas.org/doi/10.1073/...
An illusion of predictability in scientific results: Even experts confuse inferential uncertainty and outcome variability | PNAS
Traditionally, scientists have placed more emphasis on communicating inferential uncertainty
(i.e., the precision of statistical estimates) compare...
www.pnas.org
August 17, 2024 at 8:47 AM
Here's a paper that explains the difference between standard errors and standard deviations:
bmj.com/content/331/...
Here's our paper, which shows that experts (doctors, professors, data scientists) mix them up:
www.pnas.org/doi/10.1073/...
bmj.com/content/331/...
Here's our paper, which shows that experts (doctors, professors, data scientists) mix them up:
www.pnas.org/doi/10.1073/...
Reposted by Itamar
When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific "Lab Leak" hypothesis.
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
On the day of Dr. Fauci's testimony, @nytimes.com decides to run a deeply unethical OpEd with snazzy graphics and snappy headlines about the Lab Leak.
The article itself contains multiple falsehoods and deep mischaracterizations.
Let's take every point in turn 👇🧵
www.nytimes.com/interactive/...
The article itself contains multiple falsehoods and deep mischaracterizations.
Let's take every point in turn 👇🧵
www.nytimes.com/interactive/...
Opinion | Why the Pandemic Probably Started in a Lab, in 5 Key Points
The world must not continue to bear the intolerable risks of research with the potential to cause pandemics.
www.nytimes.com
June 5, 2024 at 7:35 PM
When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific "Lab Leak" hypothesis.
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
Reposted by Itamar
Instead of histograms/densities, consider plotting empirical cumulative distribution functions (ecdf). Though less intuitive, ecdfs have many advantages:
* no worries about bins/bandwidth
* directly see min, max & quantiles
* sensitive comparison of distributions
Easy to plot in #rstats 🧪
* no worries about bins/bandwidth
* directly see min, max & quantiles
* sensitive comparison of distributions
Easy to plot in #rstats 🧪
June 1, 2024 at 5:49 PM
Instead of histograms/densities, consider plotting empirical cumulative distribution functions (ecdf). Though less intuitive, ecdfs have many advantages:
* no worries about bins/bandwidth
* directly see min, max & quantiles
* sensitive comparison of distributions
Easy to plot in #rstats 🧪
* no worries about bins/bandwidth
* directly see min, max & quantiles
* sensitive comparison of distributions
Easy to plot in #rstats 🧪
Reposted by Itamar
An enthralling conversation with Daphne Koller on the convergence of A.I. and life science
erictopol.substack.com/p/daphne-kol...
erictopol.substack.com/p/daphne-kol...
March 11, 2024 at 3:38 PM
An enthralling conversation with Daphne Koller on the convergence of A.I. and life science
erictopol.substack.com/p/daphne-kol...
erictopol.substack.com/p/daphne-kol...
Reposted by Itamar
An mRNA program trying for an HIV vaccine is running into unexpected problems:
www.science.org/content/blog...
www.science.org/content/blog...
March 11, 2024 at 5:33 PM
An mRNA program trying for an HIV vaccine is running into unexpected problems:
www.science.org/content/blog...
www.science.org/content/blog...
Reposted by Itamar
For the "Ideas" series at the New York Times, I take a look at what might be called LifeGPT: letting large-language-model-like programs teach themselves biology by looking at data from millions of cells. They are learning fast. 🧪 Gift link: www.nytimes.com/2024/03/10/s...
March 10, 2024 at 1:31 PM
For the "Ideas" series at the New York Times, I take a look at what might be called LifeGPT: letting large-language-model-like programs teach themselves biology by looking at data from millions of cells. They are learning fast. 🧪 Gift link: www.nytimes.com/2024/03/10/s...