Isabel Distefano, MPH 🧬
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isabeldistefano.bsky.social
Isabel Distefano, MPH 🧬
@isabeldistefano.bsky.social
Yale MPH '25, Infectious Disease Epidemiology. Former museum worker, future public health professional. 🧪 Latina in STEM 💃🏻 | Phylo & Infectious Disease Lover | Genomics & Evolution | She/Her 👩‍🔬
Reposted by Isabel Distefano, MPH 🧬
This week in 1988: 1,000+ ACT UP demonstrators shut down the FDA headquarters, demanding (and eventually winning) action on developing HIV/AIDS treatments. ACT UP's militant and creative actions always included powerful visual artwork, and paved the way for movements in the decades to come.
October 12, 2025 at 4:12 PM
THAT little to sell your credibility and morals????
September 25, 2025 at 12:30 PM
10/10 virion cartoon imo what do y’all think?? #nokings #phsky #episky #publichealth 🛟
June 14, 2025 at 4:24 PM
Reposted by Isabel Distefano, MPH 🧬
Estimated deaths caused by Funding Discontinuation in the U.S. (until now)

90.377
Adult Deaths

188.584
Child Deaths

Deaths Per Hour
103

1/2
May 20, 2025 at 7:22 PM
In the middle of so much chaos and uncertainty there is always space for joy, light, and celebration. I graduated w/ my MPH from YSPH! Still emotionally (and physically, immediately caught a cold lol) recovering from Monday, but big shoutout to my biggest cheerleaders for being there with me 🥹🎓💃🧬🛟
May 24, 2025 at 6:16 PM
Wrapping up the MPH with one last presentation on my thesis research at Connecticut Infectious Disease Society's Annual Meeting! I'll be working through lunch and talking about our genomic epidemiological deep dive on a chronic mpox patient 🧬
May 15, 2025 at 3:37 PM
Reposted by Isabel Distefano, MPH 🧬
Uganda stopped a Sudan Ebola virus outbreak in under 3 months.
No chaos. Just fast action, local leadership, and a rapidly implemented vaccine trial.
Maybe the problem isn’t capacity in Africa after all—maybe it’s the story we keep telling about it.
open.substack.com/pub/bktitanj...
Africa’s Outbreak Response Is the Global Standard Now
From outbreak containment to clinical innovation, African nations are setting new global standards for success
open.substack.com
April 30, 2025 at 1:18 PM
Thanks for the shoutout @yaleemd.bsky.social!! It's been such a privilege to integrate within the department and work with you all for the last two years 🌟
April 29, 2025 at 3:39 PM
Reposted by Isabel Distefano, MPH 🧬
Finally, Isabel Distefano presenting on what we can learn from sequential temporal sequences of a chronic mpox case
April 28, 2025 at 3:51 PM
Reposted by Isabel Distefano, MPH 🧬
Great read. The thing I miss the most about a traditional career path is losing the opportunity to mentor women in STEM. I'm always happy to read about mentors, mentees, and the successes that come out of strong women working together towards common goals. 🧪👩‍🔬🍎🥽🧬⚛️

www.nature.com/articles/d41...
Behind every great woman in science, there’s another great woman in science
To mark International Women’s Day on 8 March, six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others.
www.nature.com
March 6, 2025 at 8:44 PM
Reposted by Isabel Distefano, MPH 🧬
5 things I did this week:
1 - admitted someone bc insulin prices went up and it was insulin or rent/food
2 - admitted someone bc a drug was covered in dec but insurance changed in jan and prior authorization still hasn’t gone thru so chronic condition that was well controlled now isn’t
February 24, 2025 at 10:39 PM
Reposted by Isabel Distefano, MPH 🧬
Besides being cruel, anticipatory obedience doesn’t work www.chemistryworld.com/opinion/scie...
Scientific institutions have a long history of anticipatory obedience
Societies should learn from this and speak up to support inclusion
www.chemistryworld.com
February 9, 2025 at 12:50 PM
Reposted by Isabel Distefano, MPH 🧬
The entire website for the NIH Office of Research on Women's Health (ORWH) is very nearly stripped bare. This is so, so devastating. orwh.od.nih.gov/research/fun...
orwh.od.nih.gov
January 31, 2025 at 6:25 PM
I knew the FDA DAP draft guidance was going to be pulled. It was only released at the end of June.
One of my friends has a grant from the #FDA to look at disparities in clinical trial research and just submitted a manuscript with the findings. She was told today by the collaborators from the #FDA to rescind it.

#Censorhip has started, we are living in authoritarian government.
US FDA drops web pages on improving clinical trial diversity
The U.S. Food and Drug Administration has pulled draft guidance from its website requiring companies to test medicines and devices in diverse populations as part of a purge of diversity, equity and inclusion efforts at U.S. health agencies.
www.reuters.com
January 26, 2025 at 7:40 PM
science and public health rn. i'm so -
a child is laying on the ground in the rain
Alt: GIF of Mei from Totoro laying face down on the mud in the pouring rain. Mood.
media.tenor.com
January 26, 2025 at 7:24 PM
Reposted by Isabel Distefano, MPH 🧬
Physician shortages in the United States are projected to worsen, especially in rural areas. Rochelle P. Walensky, MD, MPH, and Nicole C. McCann, BA, argue that broad reforms, including changes in education and compensation, are needed. Read the full report: nej.md/40BElUv

#MedSky #PublicHealth
Challenges to the Future of a Robust Physician Workforce in the United States | NEJM
Physician shortages in the United States are projected to worsen, especially in rural areas. The authors argue that broad reforms, including changes in education and compensation, are needed.
nej.md
January 19, 2025 at 8:06 PM
Reposted by Isabel Distefano, MPH 🧬
From HiV to Ebola to Covid and mpox, inequities in access is a defining feature

Grateful to @craigspencer.bsky.social for his advocacy

www.nejm.org/doi/full/10....
Ebola and a Decade of Disparities — Forging a Future for Global Health Equity | NEJM
Since the 2014–2016 West African Ebola outbreak, there have been numerous proposals and promises to reform global health infrastructure. Yet inequity remains deeply entrenched.
www.nejm.org
January 18, 2025 at 11:30 PM
Reposted by Isabel Distefano, MPH 🧬
It's important to know how people get the bird flu so that we learn how to prevent infections. @andrewpekosz.bsky.social has details on how the person in Louisiana was exposed to H5N1 🙏 publichealth.jhu.edu/2025/bird-fl...
January 17, 2025 at 2:30 PM
Reposted by Isabel Distefano, MPH 🧬
Farmworkers have avoided bird flu testing bc they don't have paid sick days. Rather than offering to cover that loss, health departments have modified guidelines so that they can work while sick.

From the CA dept of public health:
January 9, 2025 at 2:08 PM
Reposted by Isabel Distefano, MPH 🧬
Outbreak response needs to better integrate women: more women in outbreak leadership roles, better data on the effectiveness of medical countermeasures disaggregated by sex/gender, and PPE designed by women for women.
Excellent lessons learned from a group of frontline clinicians.
Women at the front line of the Marburg virus disease response in Rwanda: balancing clinical care, public health, and family life
We are female health-care workers standing on the front line of the Marburg virus disease outbreak in Rwanda. We worked in the emergency, intensive care, and Marburg virus disease isolation and treatment units during the outbreak in October, 2024. We took on the roles of caregivers, tirelessly feeding, bathing, and comforting our colleagues and family, amid the unfolding crisis. Our days were shadowed by an intense fear—monitoring ourselves for symptoms even as we continued to care for others.
www.thelancet.com
January 6, 2025 at 6:54 PM
Reposted by Isabel Distefano, MPH 🧬
Neglect, it is.

WHO finds that the direct cause of "the mystery disease" in Congo is malaria, exacerbated by malnutrition. Malaria can be *cured* by a few cheap pills, as long as it's caught early. So these are deaths of neglect.

www.reuters.com/world/africa...
December 17, 2024 at 4:16 PM
Reposted by Isabel Distefano, MPH 🧬
1/ 🚨 New study in Nature Medicine on the 2024 Marburg Virus Disease (MVD) outbreak in Rwanda. It sheds light on the genomic origins, transmission dynamics, and public health response. 🧵

Paper: doi.org/10.1038/s415...

#Marburg #GlobalHealth
Genomic and transmission dynamics of the 2024 Marburg Virus Outbreak in Rwanda - Nature Medicine
Genomic analyses from the ongoing outbreak of Marburg virus disease in Rwanda point to a single zoonotic origin of the outbreak.
doi.org
December 17, 2024 at 2:49 AM
finals currently being sabotaged by screamer in need of a lap and a nap
December 15, 2024 at 6:15 AM
Reposted by Isabel Distefano, MPH 🧬
@stephanienolen.bsky.social "took four planes, a boat, a truck and a two-day journey by motorbike to reach Kamituga, the mpox outbreak epicenter in Congo." Here's the story she found [gift link] www.nytimes.com/2024/12/07/h...
In Congo, a Medical Mystery Offers Clues to the Mpox Epidemic (Gift Article)
In a remote Congolese town, a medical mystery led to the discovery of alarming changes in the mpox virus and, eventually, to a global health emergency.
www.nytimes.com
December 8, 2024 at 5:13 PM
If my museum friends haven't read this yet, they should. Firing the administrator that brought in a $250k grant for these kids and then trying to repurpose that money to staunch their "financial crisis" is diabolical.
The California Academy of Sciences this year abruptly ended a climate action youth program after its teenage members expressed solidarity w/the museum's union.

Cal Academy fired their staff coordinator, & told the teens to stop coming in.

missionlocal.org/2024/11/cali...
Cal Academy of Sciences cuts youth program after teens show solidarity with union
The Cal Academy of Sciences dissolved a youth group for climate change after teens supported the museum workers' union with flyers.
missionlocal.org
November 25, 2024 at 3:37 PM