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immunopetit.bsky.social
Paloma Petit
@immunopetit.bsky.social
63 followers 150 following 0 posts
Cancer immunologist in the making // Phd at Maria Caffarel's breast cancer group in Biogipuzkoa // ✊🏼👩🏻‍🔬 🏳️‍🌈
Posts Replies Media Videos
Reposted by Paloma Petit
erinkevg.bsky.social
It has been a real pleasure to dive deep into the wonderful world of the unique and peculiar shape of the neutrophil nucleus, together with Ananda and Irina in the @udalovalab.bsky.social, and I'm proud this literature review is now out in @natrevimmunol.nature.com.
rdcu.be/ePKFk
November 14, 2025 at 9:33 PM
Reposted by Paloma Petit
cancerresearchuk.org
Big news! 🚨 People at high risk of lung cancer will soon be able to receive the first ever experimental vaccine designed to prevent the disease, in a world-first clinical trial. Read more: cruk.ink/4r4KXG2

@ox.ac.uk @ucl.ac.uk
Pink square graphic with black and white text which reads, ‘Pioneering trial for world’s first lung cancer prevention vaccine’
November 17, 2025 at 11:39 AM
Reposted by Paloma Petit
helloeacr.bsky.social
Join us for this exciting new virtual conference to be part of the conversation about how meaningful involvement of cancer patient advocates throughout the research process drives impactful change in cancer research.

Register now from just €25: eacr.org/conference/p...
October 16, 2025 at 8:02 AM
Reposted by Paloma Petit
iib.uam.es
🚀 New article published by Maria Alieva's group
@imaigenelab.bsky.social at the #IIBM

👉 elifesciences.org/articles/102...
October 16, 2025 at 11:40 AM
Reposted by Paloma Petit
science.org
New in #ScienceSignaling: Researchers have uncovered a molecular player that supports V(D)J recombination, a critical genetic rearrangement process that facilitates the diversity of antibodies and antigen receptors in the immune system. https://scim.ag/4hesKBp
Senataxin promotes recombination fidelity during antigen receptor gene diversification
A CRISPR screen reveals a protective role for the RNA/DNA helicase senataxin during V(D)J recombination.
scim.ag
October 15, 2025 at 3:00 PM
Reposted by Paloma Petit
science.org
The October issue of #ScienceImmunology is out!

This month's cover highlights a Review that delves into brain tumor development and examines factors contributing to the immunosuppressive brain tumor microenvironment. Learn about this and more: https://scim.ag/46HgHcl
This month’s cover illustration depicts distinct malignant glioma (upper left) and metastatic (bottom right) tumor microenvironments as collages of aperiodic penrose tiles overlaid on a stylized positron emission tomography (PET) scan of the brain.
October 13, 2025 at 9:00 PM
Reposted by Paloma Petit
oncoalert.bsky.social
NEWS FROM INDUSTRY: UPDATE ON TROPION-Breast02 #BreastCancer
Source European Pharmaceutical Review, Astrazeneca, Daiichi Sankyo

www.europeanpharmaceuticalreview.com/news/266702/...

The phase III TROPION-Breast02 trial showed that the ADC Datopotamab Deruxtecandlnk significantly improved OS & PFS
October 6, 2025 at 10:44 AM
Reposted by Paloma Petit
nature.com
This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues

go.nature.com/3VNrH1s
Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’
Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.
go.nature.com
October 6, 2025 at 10:52 AM
Reposted by Paloma Petit
johannajoyce.bsky.social
Congratulations to the recipients of the Nobel Prize in Physiology or Medicine 2025 - Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" including the identification of regulatory T cells

#NobelPrize #Tregs

@nobelprize.bsky.social 🧪🔬🏆
October 6, 2025 at 11:00 AM
Reposted by Paloma Petit
natureportfolio.nature.com
A feature in Nature Medicine explains the repercussions for investigators and patients when clinical trials are suddenly halted by US funding cuts and how they do not stop at borders. 🧪
The damage done - Nature Medicine
When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.
go.nature.com
October 4, 2025 at 10:42 PM
Reposted by Paloma Petit
science.org
“I will miss the creativity of teaching.”

On #WorldTeachersDay, check out this #ScienceWorkingLife essay from a retired professor emeritus on how she challenged students to think beyond facts—and how she learned to teach like a scientist. https://scim.ag/4nvwosR
People diving into a pool of books and figures, with text: How I learned to teach like a scientist
October 5, 2025 at 6:49 PM
Reposted by Paloma Petit
elizsmckenna.bsky.social
Now online in Cancer Discovery @aacrjournals.bsky.social: Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion doi.org/10.1158/2159...
October 1, 2025 at 3:22 PM
Reposted by Paloma Petit
jaguirreghisolab.bsky.social
Are 90% of cancer-related deaths due to metastasis? Apparently the overuse of this percentage in reviews has created confusion and questioning of whether this is true. The answer, which is as always cancer type dependent, may be in these references that also people claim they cannot find.
September 28, 2025 at 4:39 PM
Reposted by Paloma Petit
mujeresconciencia.com
#Efeméride La inmunóloga Teruko Ishizaka (1926-2019) nació un 28 de septiembre.
En 1966, junto con Kimishige Ishizaka descubrió la clase de anticuerpos inmunoglobulina E, implicada en la alergia.
Teruko Ishizaka, inmunóloga - Mujeres con ciencia
Teruko Ishizaka. Anticuerpos inmunoglobulina E. Alergia. Respuesta inmune. Hipersensibilidad. Kimishige Ishizaka.
mujeresconciencia.com
September 28, 2025 at 9:20 AM
Reposted by Paloma Petit
scinews.bsky.social
Precision targeting of STING: Challenges, innovations, and clinical outlook for cancer therapy

www.cell.com/the-innovati...
September 24, 2025 at 5:53 AM
Reposted by Paloma Petit
nu-bsa.bsky.social
Huiping Liu, MD, PhD, and team reveal how tumor–immune cell clusters fuel #BreastCancer metastasis in a pair of new studies published in @natcomms.nature.com and @jclinical-invest.bsky.social.
Investigating How Tumor-Immune Cell Clusters Drive Cancer Spread  - News Center
In a pair of studies, investigators from the lab of Huiping Liu, MD, PhD, have uncovered how specific cellular interactions in the bloodstream may be fueling the spread of breast cancer.
tinyurl.com
September 22, 2025 at 2:11 PM
Reposted by Paloma Petit
mujeresconciencia.com
Janet Lane-Claypon, la leche materna y el cáncer de mama
Janet Lane-Claypon, la leche materna y el cáncer de mama - Mujeres con ciencia
Janet Lane-Claypon. Cáncer de mama. Leche materna. Fisiología. Medicina. Bacteriología. Bioquímica. Salud materno-infantil.
mujeresconciencia.com
September 22, 2025 at 5:02 PM
Reposted by Paloma Petit
biorxiv-immuno.bsky.social
Chemotherapy Induces an IL1β-dependent Neutrophil Recruitment that Promotes Chemoresistance in Metastatic Ovarian Cancer https://www.biorxiv.org/content/10.1101/2025.09.21.677600v1
September 22, 2025 at 2:16 AM
Reposted by Paloma Petit
labwaggoner.bsky.social
TREM2 macrophages are associated with enhanced response to PD-1 blockade in human hepatocellular carcinoma @miriammerad.bsky.social
www.biorxiv.org/content/10.1...
September 14, 2025 at 5:17 PM
Reposted by Paloma Petit
cp-cellreports.bsky.social
Leukocytes use endothelial membrane tunnels to extravasate the vasculature
Leukocytes use endothelial membrane tunnels to extravasate the vasculature
During paracellular transmigration, neutrophils exit the vasculature not through simple endothelial retraction but via dynamic membrane tunnels formed by overlapping endothelial cells. Using high-resolution live imaging, the authors et al. reveal that neutrophils actively remodel endothelial membranes to create 3D exit tunnels.
dlvr.it
September 14, 2025 at 11:24 PM
Reposted by Paloma Petit
elife.bsky.social
Using #CryoEM to find the structure D-loop, formed when strands of DNA are exchanged during homologous recombination.
buff.ly/pZZfIso
September 6, 2025 at 10:44 PM
Reposted by Paloma Petit
mdanderson.bsky.social
Targeted radiation gave patients with oligometastatic kidney cancer a median of nearly 3 years without systemic therapy while maintaining high survival. A ctDNA biomarker may help personalize this approach. spr.ly/63320ADVdQ #OncSky #EndCancer
Targeted radiation helps patients with kidney cancer delay systemic therapy 
Targeted radiation helps patients with kidney cancer delay systemic therapy 
spr.ly
September 5, 2025 at 7:00 PM
Reposted by Paloma Petit
thestrugglings4.bsky.social
If global research institutions can’t retain talent, support mental health, and offer real career pathways, how sustainable is the system?

Link to the Nature article:
Postdoc depression and anxiety rates are rising, finds survey of 872 researchers
The Max Planck Society is good at attracting international postdocs but struggles to retain them, survey finds.
f.mtr.cool
August 19, 2025 at 11:02 AM
Reposted by Paloma Petit
adlunglab.com
Feeding mice galactose rewires hepatocyte metabolism to boost CD8+ T cell function via IGFBP-1, relieving exhaustion, thus suppressing tumors. Neat diet-immunity link with an interesting mechanism @natcellbio.nature.com: doi.org/10.1038/s415... 🧪
Diet-derived galactose reprograms hepatocytes to prevent T cell exhaustion and elicit antitumour immunity
Nature Cell Biology - X. Du, W. Li, G. Li, C. Guo et al. report that dietary galactose regulates the cellular crosstalk between hepatocytes and CD8+ T cells via IGFBP-1 production and IGF-1...
doi.org
August 19, 2025 at 11:03 AM