Aguirre-Ghiso Lab
@jaguirreghisolab.bsky.social
We study how micro-environmental and epigenetic mechanisms drive cancer cells into dormancy. We seek to control this biology to prevent and treat metastasis. https://einsteinmed.edu/faculty/16974/julio-aguirre-ghiso
Pinned
Honored to receive the 2026 Paget-Ewing Award, the highest honor from @metastasisresearch.bsky.social. Humbled for sharing this recognition with past awardees, all giants of metastasis research. Grateful for this acknowledgment of cancer dormancy research and for all my amazing colleagues at MRS!
What a pleasure to have hosted Dr. Joan Massague from MSKCC @mskcancercenter.bsky.social who visited us all day and delivered an exceptional lecture for our @einsteinmededu.bsky.social Montefiore Einstein Comprehensive Cancer Center distinguished lecture series. Thanks for visiting!
November 14, 2025 at 12:42 AM
What a pleasure to have hosted Dr. Joan Massague from MSKCC @mskcancercenter.bsky.social who visited us all day and delivered an exceptional lecture for our @einsteinmededu.bsky.social Montefiore Einstein Comprehensive Cancer Center distinguished lecture series. Thanks for visiting!
We wrapped the @cdi-einstein.bsky.social Retreat with four impressive projects from our workshop by Unai Heras Manterola, Lindsay Lafave, Maria Sosa, and Kamini Singh—covered dormancy & bioengineering, neoantigens, transcriptional heterogeneity & lung cancer. Wow! Thanks to all who participated!
November 7, 2025 at 6:43 PM
We wrapped the @cdi-einstein.bsky.social Retreat with four impressive projects from our workshop by Unai Heras Manterola, Lindsay Lafave, Maria Sosa, and Kamini Singh—covered dormancy & bioengineering, neoantigens, transcriptional heterogeneity & lung cancer. Wow! Thanks to all who participated!
Exciting to wrap up the presentations at our CDI retreat with two phenomenal talks by @cdi-einstein.bsky.social latest recruits who will start in 2026 @swagatag.bsky.social from @mit.edu and @samhegde.bsky.social from @mountsinainyc.bsky.social welcome to @einsteinmededu.bsky.social
November 7, 2025 at 3:20 PM
Exciting to wrap up the presentations at our CDI retreat with two phenomenal talks by @cdi-einstein.bsky.social latest recruits who will start in 2026 @swagatag.bsky.social from @mit.edu and @samhegde.bsky.social from @mountsinainyc.bsky.social welcome to @einsteinmededu.bsky.social
Today we had a phenomenal first day of our @cdi-einstein.bsky.social retreat. Great talks by @soledadsosalab.bsky.social Anna Skwarska and John McAuliffe.
November 7, 2025 at 1:08 AM
Today we had a phenomenal first day of our @cdi-einstein.bsky.social retreat. Great talks by @soledadsosalab.bsky.social Anna Skwarska and John McAuliffe.
Now the Keynote Lecture at our @cdi-einstein.bsky.social retreat delivered by @amulyasreekumar.bsky.social from the Chodosh team at University of Pennsylvania - great work!
November 6, 2025 at 2:13 PM
Now the Keynote Lecture at our @cdi-einstein.bsky.social retreat delivered by @amulyasreekumar.bsky.social from the Chodosh team at University of Pennsylvania - great work!
Getting ready to start our @cdi-einstein.bsky.social Retreat!
November 6, 2025 at 12:57 PM
Getting ready to start our @cdi-einstein.bsky.social Retreat!
I wonder if such strategy might limit early dissemination...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Anti-progestin therapy targets hallmarks of breast cancer risk - Nature
Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing epithelial–stromal remode...
www.nature.com
November 5, 2025 at 6:30 PM
I wonder if such strategy might limit early dissemination...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The @cdi-einstein.bsky.social retreat is tomorrow! Featuring 1.5 days of exciting science with keynote by Dr. Lewis Chodosh (UPenn) and talks from our faculty and students. Thanks to MECCC, SWCRF, and Pershing Square Philanthropies for their support!
November 5, 2025 at 1:54 PM
The @cdi-einstein.bsky.social retreat is tomorrow! Featuring 1.5 days of exciting science with keynote by Dr. Lewis Chodosh (UPenn) and talks from our faculty and students. Thanks to MECCC, SWCRF, and Pershing Square Philanthropies for their support!
Honored to receive the 2026 Paget-Ewing Award, the highest honor from @metastasisresearch.bsky.social. Humbled for sharing this recognition with past awardees, all giants of metastasis research. Grateful for this acknowledgment of cancer dormancy research and for all my amazing colleagues at MRS!
October 31, 2025 at 12:29 AM
Honored to receive the 2026 Paget-Ewing Award, the highest honor from @metastasisresearch.bsky.social. Humbled for sharing this recognition with past awardees, all giants of metastasis research. Grateful for this acknowledgment of cancer dormancy research and for all my amazing colleagues at MRS!
Yesterday I gave a keynote at the Invasive Lobular Breast Cancer Think Tank at MSKCC (organized by S. Oesterreich, F. Pareja Zea, C Desmedt & R Jankowitz) thanks 4 the invite. Then joined the NCI MetNet meeting @rockefeller.edu (thx 2 Sohail Tavazoie & NCI team). Our U01 trainees did an amazing job!
October 29, 2025 at 8:27 PM
Yesterday I gave a keynote at the Invasive Lobular Breast Cancer Think Tank at MSKCC (organized by S. Oesterreich, F. Pareja Zea, C Desmedt & R Jankowitz) thanks 4 the invite. Then joined the NCI MetNet meeting @rockefeller.edu (thx 2 Sohail Tavazoie & NCI team). Our U01 trainees did an amazing job!
Life Lessons from (Very Old) Bowhead Whales www.nytimes.com/2025/10/29/s...
Life Lessons from (Very Old) Bowhead Whales
www.nytimes.com
October 29, 2025 at 8:08 PM
Life Lessons from (Very Old) Bowhead Whales www.nytimes.com/2025/10/29/s...
Great to see an Educational Session on Dormancy and Reactivation of Breast Cancer Cells at Distant Metastatic Sites at the @sabcs.bsky.social meeting this year. sabcs.org/events/
Events - San Antonio Breast Cancer Symposium
sabcs.org
October 21, 2025 at 2:06 PM
Great to see an Educational Session on Dormancy and Reactivation of Breast Cancer Cells at Distant Metastatic Sites at the @sabcs.bsky.social meeting this year. sabcs.org/events/
This morning - early - I had the pleasure of presenting to the faculty and trainees of the Department of Pathology and Oncology Juntendo University School of Medicine in Tokyo. Thanks for a great Q&A and to Drs. Mezawa and Orimo for the invitation.
October 21, 2025 at 11:27 AM
This morning - early - I had the pleasure of presenting to the faculty and trainees of the Department of Pathology and Oncology Juntendo University School of Medicine in Tokyo. Thanks for a great Q&A and to Drs. Mezawa and Orimo for the invitation.
Yesterday I had the privilege of participating in a brainstorming session with the leadership of the NR2F1 Foundation to determine if our NR2F1 agonists may be of use to help individuals with the various mutations in this gene. Congratulations for the work you’re doing.
October 18, 2025 at 3:51 PM
Yesterday I had the privilege of participating in a brainstorming session with the leadership of the NR2F1 Foundation to determine if our NR2F1 agonists may be of use to help individuals with the various mutations in this gene. Congratulations for the work you’re doing.
Today we honor three giants of @einsteincellbio.bsky.social that developed their careers @einsteinmededu.bsky.social Their work has positively impacted not only science but millions of humans across the world. Congrats to Margaret Kielian, Pamela Stanley & Matthew Scharff and thank you!
October 16, 2025 at 5:29 PM
Today we honor three giants of @einsteincellbio.bsky.social that developed their careers @einsteinmededu.bsky.social Their work has positively impacted not only science but millions of humans across the world. Congrats to Margaret Kielian, Pamela Stanley & Matthew Scharff and thank you!
Congratulations to Lucia Petriz Otaño PhD student in the JAG Lab for earning the Master of Science degree in Biomedical Sciences after passing the qualifying exam! Lucia is
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
October 13, 2025 at 5:23 PM
Congratulations to Lucia Petriz Otaño PhD student in the JAG Lab for earning the Master of Science degree in Biomedical Sciences after passing the qualifying exam! Lucia is
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
Reposted by Aguirre-Ghiso Lab
Congratulations to Dr. Sosa @soledadsosalab.bsky.social, one of CDI’s inaugural recruits, on this remarkable recognition by @susangkomen.bsky.social!
This well-earned honor exemplifies and strengthens the transformative research vision at @cdi-einstein.bsky.social & @einsteinmededu.bsky.social
This well-earned honor exemplifies and strengthens the transformative research vision at @cdi-einstein.bsky.social & @einsteinmededu.bsky.social
@susangkomen.bsky.social It is a profound honor to accept the Susan G. Komen Next Generation Researcher Award. Thanks for making me feel part of
this community and our shared fight against cancer. Thanks to my lab members, my family and my husband for making this possible. @cdi-einstein.bsky.social
this community and our shared fight against cancer. Thanks to my lab members, my family and my husband for making this possible. @cdi-einstein.bsky.social
October 11, 2025 at 4:03 PM
Congratulations to Dr. Sosa @soledadsosalab.bsky.social, one of CDI’s inaugural recruits, on this remarkable recognition by @susangkomen.bsky.social!
This well-earned honor exemplifies and strengthens the transformative research vision at @cdi-einstein.bsky.social & @einsteinmededu.bsky.social
This well-earned honor exemplifies and strengthens the transformative research vision at @cdi-einstein.bsky.social & @einsteinmededu.bsky.social
Reposted by Aguirre-Ghiso Lab
@susangkomen.bsky.social It is a profound honor to accept the Susan G. Komen Next Generation Researcher Award. Thanks for making me feel part of
this community and our shared fight against cancer. Thanks to my lab members, my family and my husband for making this possible. @cdi-einstein.bsky.social
this community and our shared fight against cancer. Thanks to my lab members, my family and my husband for making this possible. @cdi-einstein.bsky.social
October 10, 2025 at 2:48 PM
@susangkomen.bsky.social It is a profound honor to accept the Susan G. Komen Next Generation Researcher Award. Thanks for making me feel part of
this community and our shared fight against cancer. Thanks to my lab members, my family and my husband for making this possible. @cdi-einstein.bsky.social
this community and our shared fight against cancer. Thanks to my lab members, my family and my husband for making this possible. @cdi-einstein.bsky.social
On Tuesday I had a great day of science and discussions visiting @danafarber.bsky.social & delivering the Harriet Tischler Memorial Lecture - thanks again Kornelia Polyak for a great day & for the stellar company during dinner with the amazing Joan Brugge and Alex Toker. @cdi-einstein.bsky.social
October 9, 2025 at 1:30 PM
On Tuesday I had a great day of science and discussions visiting @danafarber.bsky.social & delivering the Harriet Tischler Memorial Lecture - thanks again Kornelia Polyak for a great day & for the stellar company during dinner with the amazing Joan Brugge and Alex Toker. @cdi-einstein.bsky.social
Super honored to be visiting @danafarber.bsky.social to deliver the 2025 Harriet Tischler Memorial Lecture hosted by the amazing Nelly Polyak. Thanks for the invitation!
seminarsinoncology.dana-farber.org
seminarsinoncology.dana-farber.org
October 6, 2025 at 10:46 PM
Super honored to be visiting @danafarber.bsky.social to deliver the 2025 Harriet Tischler Memorial Lecture hosted by the amazing Nelly Polyak. Thanks for the invitation!
seminarsinoncology.dana-farber.org
seminarsinoncology.dana-farber.org
Reposted by Aguirre-Ghiso Lab
Amazing work from investigators at the @cdi-einstein.bsky.social. Congrats @divijverma.bsky.social and team! Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion url: aacrjournals.org/cancerdiscov...
Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion
Abstract. Environmental exposures are linked to precancerous hematologic conditions, but studies in cohorts with well-defined exposures are limited. We sequenced blood samples from a large cohort of f...
aacrjournals.org
October 3, 2025 at 6:38 PM
Amazing work from investigators at the @cdi-einstein.bsky.social. Congrats @divijverma.bsky.social and team! Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion url: aacrjournals.org/cancerdiscov...
Amazing work from investigators at the @cdi-einstein.bsky.social. Congrats @divijverma.bsky.social and team! Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion url: aacrjournals.org/cancerdiscov...
Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion
Abstract. Environmental exposures are linked to precancerous hematologic conditions, but studies in cohorts with well-defined exposures are limited. We sequenced blood samples from a large cohort of f...
aacrjournals.org
October 3, 2025 at 6:38 PM
Amazing work from investigators at the @cdi-einstein.bsky.social. Congrats @divijverma.bsky.social and team! Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion url: aacrjournals.org/cancerdiscov...