Oksana Iamshanova
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iamshanovao.bsky.social
Oksana Iamshanova
@iamshanovao.bsky.social
cardiovascular research, heart repair and regeneration, cardiac electrophysiology, secretome, ion channels, cardioprotection
Reposted by Oksana Iamshanova
📝 A new Nature study from Lippincott-Schwartz group at Howard Hughes Medical Institute reveals that secretome mRNAs are translated at specialized sites.

🔎 This uncovers a new spatial layer in how cells make secreted proteins with broad implications.

📖 Read more: https://go.nature.com/43zRK0t
November 17, 2025 at 2:49 PM
Reposted by Oksana Iamshanova
🚨🆕🧪🔬on 💓🕒 Delisle et al. 😉show the circadian clock gene BMAL1 drives sex-specific daily patterns in cardiac ion channels ⚡️❤️‍🔥 in 🐭, shaping when arrhythmias may strike in males vs females 🧠➡️❤️
#Circadian #Physiology #Heart #Arrhythmia #Sex #Science #Cardiosky
www.sciencedirect.com/science/arti...
BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability
www.sciencedirect.com
November 9, 2025 at 1:01 PM
Reposted by Oksana Iamshanova
The review process will be overseen by JGP Associate Editors Teresa Giraldez (@giraldezt.bsky.social) and Jeanne Nerbonne, with Guest Editor and subject experts Angelika Lampert (@lampertlab.bsky.social), Hugues Abriel, and Rajesh Khanna (@khannalabuf.bsky.social) 👉 rupress.org/jgp/pages/ca...
November 5, 2025 at 9:45 PM
Reposted by Oksana Iamshanova
Required reading for cell biologists to get a sense of basic statistical principles!

www.nature.com/articles/s41...
Ten essential tips for robust statistics in cell biology - Nature Cell Biology
Statistical thinking is a core part of solid, trustworthy biology. However, many studies still include insufficient sample sizes, have poor experimental design or select an incorrect statistical metho...
www.nature.com
November 4, 2025 at 7:23 PM
Reposted by Oksana Iamshanova
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...
November 4, 2025 at 5:20 PM
Reposted by Oksana Iamshanova
⏰ Abstract deadline tomorrow! Join us in Grindelwald, Feb 4–6, 2026 Worldwide Sodium Channel Conference!
Robert Stewart (Harvard) talks on Nav1.8 inhibition & new Nav blockers for pain 💥Accepted abstracts → special issue @jgp.org👉 sodiumchannelconference2026.org
#WSCC26 #SodiumChannels #PainResearch
November 1, 2025 at 8:21 AM
Reposted by Oksana Iamshanova
🎙️ Carol Ann Remme (Amsterdam UMC) joins #WSCC26 (Feb 4–6, 2026, Grindelwald, CH) to talk about cardiac sodium channels ❤️ and their role in cardiac physiology & disease.

🧠 Abstracts due Nov 2
🔗 sodiumchannelconference2026.org/WELCOME/

#NaV #ionchannels #cardiacphysiology #scienceconference
October 30, 2025 at 8:50 AM
Reposted by Oksana Iamshanova
🎙️ José Ángel Aibar, President of the Dravet Syndrome Foundation, joins #WSCC26 (Feb 4–6, 2026, Grindelwald 🇨🇭) to talk about advancing collaboration & discovery in Dravet syndrome.

🧠 Abstracts due Nov 2 – all published in a JGP special issue!
🔗 sodiumchannelconference2026.org/WELCOME/
October 29, 2025 at 10:10 AM
Reposted by Oksana Iamshanova
Voltage-gated sodium channels: Mechanisms, disease, and a growing research community. Hugues Abriel and Angelika Lampert (@lampertlab.bsky.social) introduce the Special Issue (rupress.org/jgp/search-r...) illustrating the richness and continuing momentum of this field. rupress.org/jgp/article/...
October 17, 2025 at 1:31 PM
Reposted by Oksana Iamshanova
Over a third of mothers in STEMM face maternity bias. It’s not “personal choice.” It’s systemic. Join Dr Isabel Torres on 22 Oct as we unpack how bias holds mothers back in science & what needs to change. Register now🔗 https://www.mothersinscience.com/scimomchats
#BreakTheBiasSTEMM
October 20, 2025 at 2:02 PM
Reposted by Oksana Iamshanova
Periodic reminder that the fluorescent compound in mammalian cell culture media, such as DMEM, is riboflavin (not phenol red)
October 14, 2025 at 7:51 PM
Reposted by Oksana Iamshanova
#SpatialOmics #MyocardialInfarction
#MolecularCartography 100-gene
#SeqIF 12-marker
#DeepVisualProteomics
4/24/49/96 h postMI🐭

Anti-vWF
⏬Mɸ at endocardial (not epicardial/core/border zone)
⏫infarct wall thinning
⏬🫀adaptation by 2 wk

@natcardiovascres.nature.com 2025
www.nature.com/articles/s44...
October 14, 2025 at 12:33 PM
Reposted by Oksana Iamshanova
Thanks to @snsf.ch, we are hiring two PhD students to investigate frontier topics in lipid biology using a combination of MD simulations and experiments. Preferred starting date: ASAP. Fribourg - and Switzerland - are quite nice, for both work and private life! Please spread the word!
October 13, 2025 at 2:17 PM
Reposted by Oksana Iamshanova
A cage-like network of extracellular matrix proteins anchors platelet-producing cells in the bone marrow, preventing them from entering the bloodstream too early.
buff.ly/Fz6aJvm
October 13, 2025 at 10:44 AM
Reposted by Oksana Iamshanova
This Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. Editorial by Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...
October 10, 2025 at 4:01 PM
🪄The deadline for the abstract submission #WSCC26 was extended until the 2nd November 2025
October 1, 2025 at 11:45 AM
Do not miss the opportunity to submit your abstract for #WSCC26 🚠

💡 Submit your abstracts here:
lnkd.in/eDhPUVKd

💻 More information about the event:
lnkd.in/eJw9pfMz
September 24, 2025 at 12:21 PM
Reposted by Oksana Iamshanova
Announcing the 2025 Caregiver Travel Grant recipients! 10 incredible #mothersinSTEMM have been awarded €250 to support caregiving while attending conferences. Thank you to our amazing community for making this possible! Read more 👉 www.mothersinscience.com/caregiver-tr...
#WomenInSTEM
September 23, 2025 at 12:52 PM
Reposted by Oksana Iamshanova
🚨 Save the date!
LS2 Annual Meeting 2026:
📍 Zürich | 🗓 Feb 11–12 (YSS: Feb 10)
Join us for keynotes by Sarah-Maria Fendt, Heidi McBride & Jennifer Lippincott-Schwartz + 11 symposia, poster session, & networking.
🔗 Abstracts due Nov 9
🔗 Register by Jan 11, 2026: annual-meeting.ls2.ch/2026/registr...
September 23, 2025 at 9:38 AM
Reposted by Oksana Iamshanova
EpIC News!

The first in-person EpIC meeting:
"Emerging Research on Ion Channels in Health and Disease."
19-20 February 2026
UC Davis

I can't attend myself, but this meeting organized by some of my favourite #ionchannels scientists will be 🔥🔥🔥

#SGP

sgp-epic-seminars.com/epic2026
The 2026 SGP-EpIC Symposium — SGP-EpIC Seminars
sgp-epic-seminars.com
September 20, 2025 at 5:49 AM
Reposted by Oksana Iamshanova
If you teach students, you should check out our Education Materials Library!

Download lesson plans and other teaching resources for neuroscience, cell biology, and immunology - no library card needed! #OpenScienceWeek

alleninstitute.org/materials-li...
Materials Library
Access free education resources and open data — developed with our scientists — to teach neuroscience, immunology, and cell biology.
alleninstitute.org
September 19, 2025 at 7:24 PM
Reposted by Oksana Iamshanova
🌟 Postdocs – want to become a PI?
Apply for PIs of Tomorrow 2026 at the LS2 Annual Meeting (Feb 11–12, Zurich).
Prizes, feedback, and networking: annual-meeting.ls2.ch/2026/special...
Deadline: 5 Oct 2025
🔗 form.jotform.com/211792813615...
#Career #PIsOfTomorrow #Postdoc
September 19, 2025 at 2:18 PM
Reposted by Oksana Iamshanova
After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN:
www.biorxiv.org/content/10.1...
September 17, 2025 at 3:30 PM
Reposted by Oksana Iamshanova
SCN2A loss is strongly linked to neurodevelopmental delays and, at times, seizure. In an amazing collaboration with @nadavahituv.bsky.social, led by Serena Tamura, Andrew Nelson, and Perry Spratt, we leveraged CRISPR activator approaches to rescue this loss.

rdcu.be/eGU0W
CRISPR activation for SCN2A-related neurodevelopmental disorders
Nature - Using SCN2A haploinsufficiency as a proof-of-concept, upregulation of the existing functional gene copy through CRISPR activation was able to rescue neurological-associated phenotypes in...
rdcu.be
September 17, 2025 at 6:27 PM