Marie Huynh
@huynhm.bsky.social
Striving to always understand more about science - and people.
Chemical biology, radiopharmaceutical chemistry, molecular biology & metals in medicine.
PhD CPT-PSL University | PharmD Paris Cité University. Post-doc UW-Madison.
She/her. Views are my own.
Chemical biology, radiopharmaceutical chemistry, molecular biology & metals in medicine.
PhD CPT-PSL University | PharmD Paris Cité University. Post-doc UW-Madison.
She/her. Views are my own.
Reposted by Marie Huynh
📣Job opportunities in Brussels from Jan 2026 🇧🇪 Join our team to help develop new ANION RECEPTORS for phosphate and other oxoanions ➡️ Sensing and transmembrane transport for Environment & Health applications. PhD students: euraxess.ec.europa.eu/jobs/383323, PostDoc: euraxess.ec.europa.eu/jobs/383310
October 27, 2025 at 5:28 PM
📣Job opportunities in Brussels from Jan 2026 🇧🇪 Join our team to help develop new ANION RECEPTORS for phosphate and other oxoanions ➡️ Sensing and transmembrane transport for Environment & Health applications. PhD students: euraxess.ec.europa.eu/jobs/383323, PostDoc: euraxess.ec.europa.eu/jobs/383310
Reposted by Marie Huynh
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Profiling the proteome-wide selectivity of diverse electrophiles - Nature Chemistry
Covalent inhibitors are powerful entities in drug discovery. Now the amino acid selectivity and reactivity of a diverse electrophile library have been assessed proteome-wide using an unbiased workflow...
www.nature.com
October 30, 2025 at 10:27 AM
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Reposted by Marie Huynh
Come work with us! We have a PhD opportunity available with the Sedgwick and Giuliani groups. Please reach out if you are interested.
@CRUKCOLcentre
www.colcc.ac.uk/2026-phd-pro...
@CRUKCOLcentre
www.colcc.ac.uk/2026-phd-pro...
2026 PhD Project Sedgwick
Metal-based Photoimmunotherapy Agents for the Targeted Treatment of Neuroblastoma
Primary supervisor: Adam Sedgwick, King's College London
Secondary supervisor: Jeannine Hess, The Francis Crick Ins...
www.colcc.ac.uk
October 13, 2025 at 7:26 AM
Come work with us! We have a PhD opportunity available with the Sedgwick and Giuliani groups. Please reach out if you are interested.
@CRUKCOLcentre
www.colcc.ac.uk/2026-phd-pro...
@CRUKCOLcentre
www.colcc.ac.uk/2026-phd-pro...
Reposted by Marie Huynh
Good example: bsky.app/profile/nano...
September 27, 2025 at 11:34 AM
Good example: bsky.app/profile/nano...
Reposted by Marie Huynh
Our latest manuscript has now appeared in Analytical Chemistry! We designed SODA (sulfoxide-diazirine). It enables photoaffinity labeling and subsequent MS-based cleavage of the probe, leaving a small fingerprint on the modified digested peptide.
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Sulfoxide-diazirine (SODA) as a Cleavable Photoaffinity Group To Enable the Identification of Photolabeled Modification Sites via LC–MS3
Photoaffinity labeling is a common approach in chemical proteomics for the identification of small-molecule probe targets. However, the modification site on the target protein remains difficult to ide...
pubs.acs.org
August 25, 2025 at 1:51 PM
Our latest manuscript has now appeared in Analytical Chemistry! We designed SODA (sulfoxide-diazirine). It enables photoaffinity labeling and subsequent MS-based cleavage of the probe, leaving a small fingerprint on the modified digested peptide.
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Reposted by Marie Huynh
Excited to share a new preprint from the lab. We show that PTMs like phosphorylation & glycosylation dynamically reshape proteome-wide ligandability in cells, including proteins like KRAS. Great collaboration with the Huang Lab, @forlilab.bsky.social and BMS. www.biorxiv.org/content/10.1...
Post-Translational Modifications Remodel Proteome-Wide Ligandability
Post-translational modifications (PTMs) vastly expand the diversity of human proteome, dynamically reshaping protein activity, interactions, and localization in response to environmental, pharmacologi...
www.biorxiv.org
August 3, 2025 at 2:36 PM
Excited to share a new preprint from the lab. We show that PTMs like phosphorylation & glycosylation dynamically reshape proteome-wide ligandability in cells, including proteins like KRAS. Great collaboration with the Huang Lab, @forlilab.bsky.social and BMS. www.biorxiv.org/content/10.1...
Reposted by Marie Huynh
#PhDposition #OrganicChemistry #ChemBio - deadline 03.08 - please RT ❤️ Application online stellenangebote.uni-marburg.de/jobposting/d...
July 29, 2025 at 12:29 PM
#PhDposition #OrganicChemistry #ChemBio - deadline 03.08 - please RT ❤️ Application online stellenangebote.uni-marburg.de/jobposting/d...
Reposted by Marie Huynh
Exciting News!🎉
@kanishkasikligar.bsky.social & I are co-chairing the Metals in Medicine GRS 2026-Transforming Medicine with Inorganic Chemistry! 🧪 🔬💊
A must for early-career researchers to explore cutting-edge science & network. Join us in June 2026! 👇
🔗 lnkd.in/e7JJYY3R
@kanishkasikligar.bsky.social & I are co-chairing the Metals in Medicine GRS 2026-Transforming Medicine with Inorganic Chemistry! 🧪 🔬💊
A must for early-career researchers to explore cutting-edge science & network. Join us in June 2026! 👇
🔗 lnkd.in/e7JJYY3R
July 29, 2025 at 4:45 PM
Exciting News!🎉
@kanishkasikligar.bsky.social & I are co-chairing the Metals in Medicine GRS 2026-Transforming Medicine with Inorganic Chemistry! 🧪 🔬💊
A must for early-career researchers to explore cutting-edge science & network. Join us in June 2026! 👇
🔗 lnkd.in/e7JJYY3R
@kanishkasikligar.bsky.social & I are co-chairing the Metals in Medicine GRS 2026-Transforming Medicine with Inorganic Chemistry! 🧪 🔬💊
A must for early-career researchers to explore cutting-edge science & network. Join us in June 2026! 👇
🔗 lnkd.in/e7JJYY3R
Reposted by Marie Huynh
Opportunity for computational chemist for cyclic peptide design at AbbVie (North Chicago USA) #CADD #CompChem #cheminformatics #AI #ML #ChemJobs #chemsky 🧪
jobs.smartrecruiters.com/AbbVie/37439...
jobs.smartrecruiters.com/AbbVie/37439...
Sr Scientist I/II Informatics - Peptide Design
Company Description: AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to ...
jobs.smartrecruiters.com
July 4, 2025 at 6:22 AM
Opportunity for computational chemist for cyclic peptide design at AbbVie (North Chicago USA) #CADD #CompChem #cheminformatics #AI #ML #ChemJobs #chemsky 🧪
jobs.smartrecruiters.com/AbbVie/37439...
jobs.smartrecruiters.com/AbbVie/37439...
Reposted by Marie Huynh
‼️I'm looking for a postdoc‼️ Come join effort in using metagenomes to quantify microbial catabolic potential and carbon substrate availability at the ecosystem level. We seek to understand evolutionary forces shaping the carbon cycle. Part of ccomp-stc.org
careers.peopleclick.com/careerscp/cl...
careers.peopleclick.com/careerscp/cl...
Postdoctoral Associate
MIT - Postdoctoral Associate - Cambridge MA 02139
careers.peopleclick.com
June 18, 2025 at 2:39 PM
‼️I'm looking for a postdoc‼️ Come join effort in using metagenomes to quantify microbial catabolic potential and carbon substrate availability at the ecosystem level. We seek to understand evolutionary forces shaping the carbon cycle. Part of ccomp-stc.org
careers.peopleclick.com/careerscp/cl...
careers.peopleclick.com/careerscp/cl...
Reposted by Marie Huynh
Working link here! www.biorxiv.org/content/10.1...
June 25, 2025 at 6:12 PM
Working link here! www.biorxiv.org/content/10.1...
Reposted by Marie Huynh
Given the need for more interdisciplinary and curiosity-driven research, we are offering up to £200k awards for research on the boundary between social science/humanities and science or engineering
www.thebritishacademy.ac.uk/funding/apex...
www.thebritishacademy.ac.uk/funding/apex...
APEX Awards
The APEX awards are a new funding opportunity designed to promote collaboration across academic disciplines through the support of world-leading interdisciplinary research projects.
www.thebritishacademy.ac.uk
June 25, 2025 at 5:03 PM
Given the need for more interdisciplinary and curiosity-driven research, we are offering up to £200k awards for research on the boundary between social science/humanities and science or engineering
www.thebritishacademy.ac.uk/funding/apex...
www.thebritishacademy.ac.uk/funding/apex...
Reposted by Marie Huynh
En se désengageant de l’enseignement supérieur et de la recherche depuis vingt ans, en discréditant la parole scientifique, l’Etat est largement responsable de la régression française en matière d’innovation.
Délaissée par l'Etat français, la recherche publique décroche
www.altereco.media
May 23, 2025 at 1:03 PM
En se désengageant de l’enseignement supérieur et de la recherche depuis vingt ans, en discréditant la parole scientifique, l’Etat est largement responsable de la régression française en matière d’innovation.
Reposted by Marie Huynh
L'occasion de rappeler que la déforestation induite par l'extraction est bien davantage le fait de l'extraction d'or et de charbons que des métaux pour la transition. Que les discours "anti-mines" se concentrent contre la transition est très étrange.
www.energy-transitions.org/publications...
www.energy-transitions.org/publications...
May 7, 2025 at 12:28 PM
L'occasion de rappeler que la déforestation induite par l'extraction est bien davantage le fait de l'extraction d'or et de charbons que des métaux pour la transition. Que les discours "anti-mines" se concentrent contre la transition est très étrange.
www.energy-transitions.org/publications...
www.energy-transitions.org/publications...
Reposted by Marie Huynh
This is interesting — a recent study of mode share (the % share of transportation trips by car, transit, walking, biking etc) relative to city size and income levels in almost 800 cities in 61 countries. Interesting results. HT @davidzipper.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
April 29, 2025 at 5:46 PM
This is interesting — a recent study of mode share (the % share of transportation trips by car, transit, walking, biking etc) relative to city size and income levels in almost 800 cities in 61 countries. Interesting results. HT @davidzipper.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Marie Huynh
☕Taniguchi et al. structurally analyse #NuclearPore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear envelope. They link nuclear pore complex elasticity to nuclear envelope integrity in differentiation.
go.nature.com/42PJurY
go.nature.com/42PJurY
Nuclear pores safeguard the integrity of the nuclear envelope - Nature Cell Biology
Taniguchi et al. structurally analyse nuclear pore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear envelope. They link nuclear pore ...
go.nature.com
April 28, 2025 at 12:59 PM
☕Taniguchi et al. structurally analyse #NuclearPore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear envelope. They link nuclear pore complex elasticity to nuclear envelope integrity in differentiation.
go.nature.com/42PJurY
go.nature.com/42PJurY
Reposted by Marie Huynh
---ATTENTION---ATTENTION---
I have now heard from several reliable sources outside and inside NSF that the fears about research.gov are not well-founded.
I apologize for contributing to excessive concern.
But, better safe than sorry these days...
I have now heard from several reliable sources outside and inside NSF that the fears about research.gov are not well-founded.
I apologize for contributing to excessive concern.
But, better safe than sorry these days...
a cartoon of spongebob and patrick standing next to each other on a wooden floor
ALT: a cartoon of spongebob and patrick standing next to each other on a wooden floor
media.tenor.com
April 25, 2025 at 4:03 PM
---ATTENTION---ATTENTION---
I have now heard from several reliable sources outside and inside NSF that the fears about research.gov are not well-founded.
I apologize for contributing to excessive concern.
But, better safe than sorry these days...
I have now heard from several reliable sources outside and inside NSF that the fears about research.gov are not well-founded.
I apologize for contributing to excessive concern.
But, better safe than sorry these days...
Reposted by Marie Huynh
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
a cartoon of a man holding a frying pan and a spoon with red alert written above him
ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him
media.tenor.com
April 24, 2025 at 9:09 PM
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
Reposted by Marie Huynh
Senior manager position available in medicinal chemistry at AstraZeneca Gothenburg: careers.astrazeneca.com/job/gothenbu...
PS. Don't contact me, I'm not involved in hiring. Just follow the link.
PS. Don't contact me, I'm not involved in hiring. Just follow the link.
Senior Director, Medicinal Chemistry Strategy at AstraZeneca
Learn more about applying for Senior Director, Medicinal Chemistry Strategy at AstraZeneca
careers.astrazeneca.com
April 24, 2025 at 7:05 AM
Senior manager position available in medicinal chemistry at AstraZeneca Gothenburg: careers.astrazeneca.com/job/gothenbu...
PS. Don't contact me, I'm not involved in hiring. Just follow the link.
PS. Don't contact me, I'm not involved in hiring. Just follow the link.
Reposted by Marie Huynh
Pleased to share our new paper out in 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 𝘰𝘧 𝘊𝘭𝘪𝘯𝘪𝘤𝘢𝘭 𝘐𝘯𝘷𝘦𝘴𝘵𝘪𝘨𝘢𝘵𝘪𝘰𝘯 led by Monika Kumaraswamy, MD, now Chief of Infectious Diseases UTexas-Tyler
Is minimimum inhibitory concentration (MIC) testing the gold standard for antibiotic-resistant superbugs? 🦠 🧫
🧵 1/6
www.jci.org/articles/vie...
Is minimimum inhibitory concentration (MIC) testing the gold standard for antibiotic-resistant superbugs? 🦠 🧫
🧵 1/6
www.jci.org/articles/vie...
April 23, 2025 at 1:37 PM
Pleased to share our new paper out in 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 𝘰𝘧 𝘊𝘭𝘪𝘯𝘪𝘤𝘢𝘭 𝘐𝘯𝘷𝘦𝘴𝘵𝘪𝘨𝘢𝘵𝘪𝘰𝘯 led by Monika Kumaraswamy, MD, now Chief of Infectious Diseases UTexas-Tyler
Is minimimum inhibitory concentration (MIC) testing the gold standard for antibiotic-resistant superbugs? 🦠 🧫
🧵 1/6
www.jci.org/articles/vie...
Is minimimum inhibitory concentration (MIC) testing the gold standard for antibiotic-resistant superbugs? 🦠 🧫
🧵 1/6
www.jci.org/articles/vie...
Reposted by Marie Huynh
Petit tuto pour vous opposer à l'utilisation de vos données par Instagram. (Ça prend deux minutes, et il y a une fenêtre de commentaires pour pouvoir les insulter)
Vous n'avez pas reçu le mail de Meta pour opt-out de leur IA ? Vous inquiétez pas voici un tuto ! Car oui si vous aviez déjà fait les démarches l'an dernier, ça ne compte pas, c'est un autre formulaire validé par l'Europe cette fois HAHAHAHA.
Pour instagram :
Pour instagram :
April 18, 2025 at 12:46 PM
Petit tuto pour vous opposer à l'utilisation de vos données par Instagram. (Ça prend deux minutes, et il y a une fenêtre de commentaires pour pouvoir les insulter)
Reposted by Marie Huynh
‼️‼️Postdoc position opening for photoswitches synthesis #OrganicChemistry #ChemBio Apply online here: stellenangebote.uni-marburg.de/jobposting/e...
Deadline 27.04🗓️
please RT ❤️
Deadline 27.04🗓️
please RT ❤️
April 17, 2025 at 2:43 PM
‼️‼️Postdoc position opening for photoswitches synthesis #OrganicChemistry #ChemBio Apply online here: stellenangebote.uni-marburg.de/jobposting/e...
Deadline 27.04🗓️
please RT ❤️
Deadline 27.04🗓️
please RT ❤️
Reposted by Marie Huynh
We’re looking to help fund projects that tackle inequality or highlight the lived experiences of underrepresented groups in chemistry.
Apply by 5 May for up to £5,000 to bring your inclusion and diversity project to life: buff.ly/LpxjBOU
#ChemSky
Apply by 5 May for up to £5,000 to bring your inclusion and diversity project to life: buff.ly/LpxjBOU
#ChemSky
April 15, 2025 at 3:03 PM
We’re looking to help fund projects that tackle inequality or highlight the lived experiences of underrepresented groups in chemistry.
Apply by 5 May for up to £5,000 to bring your inclusion and diversity project to life: buff.ly/LpxjBOU
#ChemSky
Apply by 5 May for up to £5,000 to bring your inclusion and diversity project to life: buff.ly/LpxjBOU
#ChemSky