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guymalkinson.bsky.social
@guymalkinson.bsky.social
140 followers 38 following 4 posts
All things cerebrovascular 🧠 and 🔬
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Reposted
auroralkraus.bsky.social
Check out our recent preprint, "Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish."

lnkd.in/gN7z6th4
November 18, 2025 at 2:42 AM
Reposted
biorxiv-neursci.bsky.social
Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish https://www.biorxiv.org/content/10.1101/2025.11.14.688311v1
November 17, 2025 at 12:16 AM
Reposted
evborg.bsky.social
Call for European 2030 IVBM Bid

Application deadline is March 1st, 2026.

More information:https://evbo.org/index.php/call-for-european-2030-ivbm-bid/
Call for European 2030 IVBM Bid - European Vascular Biology Organisation
International Vascular Biology Meeting The European Vascular Biology Organization (EVBO) invites proposals from motivated scientists representing qualified institutions, national societies, and/or…
evbo.org
November 6, 2025 at 9:51 AM
Reposted
kwolbachia.bsky.social
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
Reposted
beckrichardson.bsky.social
Our new paper on valve disease in aged #zebrafish is out! onlinelibrary.wiley.com/doi/10.1111/... This has been a long running collaborative effort with contributions from lots of great people!
Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease
Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibi...
onlinelibrary.wiley.com
October 13, 2025 at 11:01 AM
Reposted
frenchzebrafish.bsky.social
Granted by @biologists.bsky.social and the European Zebrafish Society, the 2nd French Zebrafish Meeting will be held in Toulouse, October 29-31st, 2025.
A few spots are still available—Register now to secure your place.
👉https://www.frenchzebrafishmeeting.fr/

#zebrafish #researchcommunity
September 26, 2025 at 12:08 PM
guymalkinson.bsky.social
@biologists.bsky.social
frenchzebrafish.bsky.social French Zebrafish Meeting @frenchzebrafish.bsky.social · Sep 25
🐟2ndFrenchZebrafishMeeting – Latest news! 🐟
📢 Abstract submission is now closed, but you can still submit a poster!
All posters will be presented, providing an excellent opportunity to share your work.
👉https://www.frenchzebrafishmeeting.fr/poster-submission

#zebrafish #FZM25 #postersession
September 25, 2025 at 12:49 PM
Reposted
frenchzebrafish.bsky.social
🐟2ndFrenchZebrafishMeeting – Latest news! 🐟
📢 Abstract submission is now closed, but you can still submit a poster!
All posters will be presented, providing an excellent opportunity to share your work.
👉https://www.frenchzebrafishmeeting.fr/poster-submission

#zebrafish #FZM25 #postersession
September 25, 2025 at 8:17 AM
guymalkinson.bsky.social
Abstract submission deadline extended!
frenchzebrafish.bsky.social French Zebrafish Meeting @frenchzebrafish.bsky.social · Sep 17
Many of you have informed us that you are behind schedule in submitting your abstract for the French Zebrafish Meeting.
The scientific committee has therefore agreed to extend the deadline to September 22.
This will be the final deadline, so hurry up !

#zebrafish #FZM25 @bensimonbrito.bsky.social
September 17, 2025 at 11:08 AM
Reposted
bensimonbrito.bsky.social
🚨 Don’t miss it! Abstract submission closes Monday, Sept 15. frenchzebrafishmeeting.fr
Fantastic keynote speaker @KarinaYaniv and a great opportunity to connect with the @FrenchZebrafish Community. All talks will be in English. Join us! #FZM #zebrafish
frenchzebrafish.bsky.social French Zebrafish Meeting @frenchzebrafish.bsky.social · Aug 26
2nd French Zebrafish Meeting : Abstract's submission deadline extended to September 15th 2025.
Spread the word ... Registration deadline : October 10th.
More info on www.frenchzebrafishmeeting.fr
#zebrafish #FZM2025 #scientificcommunity #biology #behavior #diseasemodels #regeneration #evolution
September 13, 2025 at 4:05 AM
Reposted
frenchzebrafish.bsky.social
2nd French Zebrafish Meeting : Abstract's submission deadline extended to September 15th 2025.
Spread the word ... Registration deadline : October 10th.
More info on www.frenchzebrafishmeeting.fr
#zebrafish #FZM2025 #scientificcommunity #biology #behavior #diseasemodels #regeneration #evolution
August 26, 2025 at 2:30 PM
Reposted
silvia-anderle.bsky.social
Delighted to share our latest review in Nature Reviews Neuroscience!
We examine the growing evidence that vascular dysfunction plays a key role in cognitive decline in ageing and dementia, and argue that preserving/restoring CBF should be central to future therapies.
www.nature.com/articles/s41...
The vascular contribution to cognitive decline in ageing and dementia - Nature Reviews Neuroscience
Growing evidence suggests that reduced cerebral blood flow contributes to cognitive decline in ageing and dementia. Attwell and colleagues discuss the underlying mechanisms and functional consequences...
www.nature.com
August 5, 2025 at 10:26 AM
Reposted
evborg.bsky.social
#EVBOSeminarSeries Moderated by Joanna Kalucka. Speakers: Ralf Adams and Mariona Graupera. ⏰When: Wednesday, 18th June 2025, 3PM EU time (2PM UK). Place: online. See you there! For registration evbo.org
June 13, 2025 at 12:00 PM
Reposted
zebrafishrock.bsky.social
Due to their aquatic environment, #zebrafish are perfect for small molecule drug screens. Many drugs have been repurposed for novel treatments such as COX inhibitors in leukemia & glucocorticoids in long QT syndrome. For more, read this Nature review ($): doi.org/10.1038/nrd4... #ZebrafishFunFacts 🧪
Figure taken from MacRae & Peterson (2015): How suitable are zebrafish for discovering human drugs? Although zebrafish enable in vivo studies on a large scale, questions remain about how relevant the findings are for drug discovery. Recent studies have begun to elucidate the degree of conservation between humans and zebrafish, which share 82% of disease-associated targets and a large number of drug metabolism pathways (as illustrated by the mass spectrometry of metabolic by-products). Zebrafish physiology is often well conserved (sometimes more so than rodent physiology); for example, cardiac electrophysiology (illustrative electrocardiogram (ECG) tracings from each organism are shown). Several compounds discovered in zebrafish screens have been shown to exhibit similar effects in rodent models and humans, including eight out of ten compounds tested by our groups. m/z, mass to charge ratio.
June 6, 2025 at 2:40 PM
Reposted
zebrafishrock.bsky.social
Masters of regeneration? #Zebrafish are capable of regenerating their fins, spinal cord, pancreas, skin, retina, heart, liver, brain, tendons, hair cells, & kidney. For more info on this amazing species, read this primer on regeneration: journals.biologists.com/dev/article/... #ZebrafishFunFacts 🧪
Organ regeneration in the zebrafish. Summary of some of the organs and tissues used for regeneration studies in zebrafish. Preferred injury models are annotated for each organ. Image and text credit to Marques et al. (2019) https://doi.org/10.1242/dev.167692
May 10, 2025 at 8:14 AM
Reposted
dev-journal.bsky.social
Skin T cells form stable blebs to move

Read this Research Highlight showcasing work from Tanner Robertson, Anna Huttenlocher and colleagues:
journals.biologists.com/dev/article/...
🎥T cells migrate with F-actin-poor leading edges in the epidermis of scale explants
April 30, 2025 at 8:51 AM
Reposted
siegenthalerlab.bsky.social
Great new work led by @biomarina-vg.bsky.social on zebrafish meninges!

Particularly 🤩 is the descriptions of ependymin-expressing meningeal cells (not a fibroblast!) & ablation studies showing their essential role in viability. So much more to learn!

Congrats Marina & team on this great work! 🦓🐟🧠
Adult zebrafish possess complex multilayered cephalic meninges. Transmission electron micrograph (TEM) images of transverse sections through the dorsal heads of adult zebrafish, at the level of the optic tecta. A, Pseudocolored overview image of the cephalic meninges, revealing multiple tissue layers between the skull and the brain parenchyma. B, Dorsal surface of a dissected adult zebrafish brain, showing the leptomeninges partially peeling away from the underlying brain parenchyma. C, Higher magnification image of the boxed region in panel B, showing multiple leptomeningeal cell layers separated by membrane bilayers (red arrowheads), delimited ventrally by a well-defined basal lamina (pseudocolored purple). D, Nucleated red blood cell-containing blood vessel embedded within the leptomeninges, with desmosomes and junctions connecting individual endothelial cells (arrows). E, Higher magnification image of the boxed region in panel D, showing a portion of the vessel wall with a characteristic endothelial cell-cell junction (arrow). F, Higher magnification image of collagen fibers in the adult zebrafish leptomeninges. G, Pseudocolored overview image of the cephalic meninges, showing separated heavily pigment dura mater (dural meninges) and leptomeninges. multiple tissue layers (pseudocolored) between the skull and the brain parenchyma. H, Higher magnification image of the boxed region in panel G, showing bilayered dural meninges with periosteal dura adjacent to the skull with an underlying meningeal dural cell layer with numerous large melanophore pigment granules (arrows). Scale bars = 3 µm (A), 4 µm (B,G), 1 µm (C,H), 2 µm (D), 0.3 µm (E), and 0.2 µm (F). M, Dorsal view of an adult casper zebrafish head with the optic tectum and cerebellum clearly visible through the thin, translucent skull. The yellow box shows the approximate region depicted in panels N and O. N,O, Confocal images of the meninges imaged through the intact skull of a living Tg(mrc1a:egfp)y251, Tg(epd:mcherry)y715 double transgenic adult zebrafish, showing (N) mrc1a:egfp-positive FGPs and lymphatics (green) and epd:mcherry-positive LBCs (magenta), or (O) only epd:mcherry-positive LBCs (magenta). P, High-resolution, high magnification confocal Z-stack through the leptomeninges on the surface of a dissected Tg(mrc1a:egfp)y251, Tg(epd:mcherry)y715 double transgenic adult zebrafish brain, showing LBCs (magenta) and FGPs (green). The large center image is a dorsal XY view of the reconstructed image stack, and the images below and to the right show single-plane XZ and YZ views along the planes noted by the dashed lines (xz-1, xz-2, yz).
April 20, 2025 at 2:40 PM
Reposted
bensimonbrito.bsky.social
Are postdocs the rarest species, or is it just me? We have two funded positions—apply now and join us on these exciting projects! #zebrafish #zebrafishcareers #iPSC #devbio #regeneration
March 31, 2025 at 7:37 PM
Reposted
braincomms.bsky.social
Lindzon et al. report that a new zebrafish model for Charcot-Marie-Tooth 4B3 reveals brain changes, dysmyelination, and altered gene expression, providing a tool for studying therapies. Please read at: buff.ly/EOyYCHJ
March 30, 2025 at 3:01 PM
Reposted
mcgraillab.bsky.social
Zebrafish Community Cre/lox Resource website (ZebrafishCCR) will be online soon!
March 29, 2025 at 6:21 PM
Reposted
taijamakinenlab.bsky.social
If you’re curious about why lymphatic endothelial cells have their jigsaw puzzle-like shape,
check out our paper
@Nature
rdcu.be/eejhZ
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
Nature - Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result...
rdcu.be
March 20, 2025 at 9:15 AM
Reposted
zebrafishrock.bsky.social
Highlights new work from De Val Lab at @ludwigcancer.bsky.social

🔗 to original research: elifesciences.org/articles/102...
March 20, 2025 at 6:46 AM
Reposted
elkslab.bsky.social
Exciting ZDMS Infection and Inflammation online RIG meetups are rapidly approaching (March 26th and April 2nd). They are FREE TO ATTEND, but please do register here: www.zdmsociety.org/2025-zdms-ri...
March 18, 2025 at 10:32 AM
Reposted
bensimonbrito.bsky.social
Are you passionate about live-imaging microscopy? Do you have a special talent for working with iPSCs? Or are you simply a zebrafish aficionado? 🐟
We have 2 funded postdoctoral positions in our lab (cbi-toulouse.fr/eng/equipe-b...).
Join us and apply now!
Please spread the word 🙏
March 13, 2025 at 3:35 PM
Reposted
zebrafishrock.bsky.social
Are you involved w/ #zebrafish research in the UK? Since new regulations went into effect in Sept 2024, it’s been nearly impossible to import our fishy friends from abroad. Help us change that w/ this call to action! 🙏 To download templates to use in emails, visit: www.dropbox.com/scl/fi/p9rra... 🧪
Megaphone with a speech bubble saying ‘A call to action’ with the text ‘Please send an email to fish.health.inspectorate@cefas.gov.uk if you are concerned about importing fish to the UK. Templates are provided. Deadline 14th of March, 2025
March 7, 2025 at 5:58 PM