Caroline Fecher
@fecherc.bsky.social
Postdoc in the Pagliarini lab | @ WashU Medicine | LMU & TUM alumna
Studying mitochondria in the CNS using imaging and mass spectrometry techniques
Studying mitochondria in the CNS using imaging and mass spectrometry techniques
Reposted by Caroline Fecher
ONE WEEK UNTIL THE DEADLINE!
Spend the summer in the Grass Lab at the @mblscience.bsky.social in Woods Hole, Massachusetts, conducting your own original neuroscience research in a richly supportive shared environment.
grassfoundation.org/application-...
Spend the summer in the Grass Lab at the @mblscience.bsky.social in Woods Hole, Massachusetts, conducting your own original neuroscience research in a richly supportive shared environment.
grassfoundation.org/application-...
November 25, 2025 at 6:39 PM
ONE WEEK UNTIL THE DEADLINE!
Spend the summer in the Grass Lab at the @mblscience.bsky.social in Woods Hole, Massachusetts, conducting your own original neuroscience research in a richly supportive shared environment.
grassfoundation.org/application-...
Spend the summer in the Grass Lab at the @mblscience.bsky.social in Woods Hole, Massachusetts, conducting your own original neuroscience research in a richly supportive shared environment.
grassfoundation.org/application-...
Reposted by Caroline Fecher
Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
bit.ly
November 18, 2025 at 2:44 PM
Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows
Reposted by Caroline Fecher
Programmed axon degeneration: mechanism, inhibition and therapeutic potential — a Review by Andrea Loreto & Lukas J. Neukomm
@andrea-loreto.bsky.social @lukasneukomm.bsky.social @sydneysavesight.bsky.social @sydney.edu.au
#neuroscience #neuroskyence
www.nature.com/articles/s41...
@andrea-loreto.bsky.social @lukasneukomm.bsky.social @sydneysavesight.bsky.social @sydney.edu.au
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Programmed axon degeneration: mechanism, inhibition and therapeutic potential - Nature Reviews Neuroscience
Programmed axon degeneration (PAxD) is activated by axotomy to execute the self-destruction of a severed distal axon. It may also be activated by some non-axotomy insults, suggesting it has a role in ...
www.nature.com
November 13, 2025 at 11:49 AM
Programmed axon degeneration: mechanism, inhibition and therapeutic potential — a Review by Andrea Loreto & Lukas J. Neukomm
@andrea-loreto.bsky.social @lukasneukomm.bsky.social @sydneysavesight.bsky.social @sydney.edu.au
#neuroscience #neuroskyence
www.nature.com/articles/s41...
@andrea-loreto.bsky.social @lukasneukomm.bsky.social @sydneysavesight.bsky.social @sydney.edu.au
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Reposted by Caroline Fecher
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution — a Review by Jeffrey J. Colgren & Pawel Burkhardt
@jeffcolgren.bsky.social @pawelburkhardt.bsky.social
#neuroscience #neuroskyence
www.nature.com/articles/s41...
@jeffcolgren.bsky.social @pawelburkhardt.bsky.social
#neuroscience #neuroskyence
www.nature.com/articles/s41...
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution - Nature Reviews Neuroscience
Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were co-opted into functional assemblies and...
www.nature.com
November 6, 2025 at 4:21 PM
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution — a Review by Jeffrey J. Colgren & Pawel Burkhardt
@jeffcolgren.bsky.social @pawelburkhardt.bsky.social
#neuroscience #neuroskyence
www.nature.com/articles/s41...
@jeffcolgren.bsky.social @pawelburkhardt.bsky.social
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Reposted by Caroline Fecher
Our next profile is live! Dr. Emi Nagoshi studies the genetic and molecular basis of circadian rhythms and Parkinsons disease. Follow the link below to listen and learn more!
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuroscience
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuroscience
October 29, 2025 at 4:32 PM
Our next profile is live! Dr. Emi Nagoshi studies the genetic and molecular basis of circadian rhythms and Parkinsons disease. Follow the link below to listen and learn more!
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuroscience
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuroscience
Reposted by Caroline Fecher
Registration for our in-person event is still open! We hope to see you all in San Diego!
🚨REGISTRATION IS OPEN!🚨
We're so excited to host our first-ever, in-person event! Join us for panel discussions, a keynote address, and the opportunity to meet many amazing women in Neuroscience💜
Please register to attend by November 1st:
docs.google.com/forms/d/e/1F...
We can't wait!
We're so excited to host our first-ever, in-person event! Join us for panel discussions, a keynote address, and the opportunity to meet many amazing women in Neuroscience💜
Please register to attend by November 1st:
docs.google.com/forms/d/e/1F...
We can't wait!
October 23, 2025 at 1:58 PM
Registration for our in-person event is still open! We hope to see you all in San Diego!
Reposted by Caroline Fecher
Whoo hoo! The final version of our first paper is online! So proud of the team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Redirecting
kwnsfk27.r.eu-west-1.awstrack.me
October 10, 2025 at 4:47 PM
Whoo hoo! The final version of our first paper is online! So proud of the team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Reposted by Caroline Fecher
The neuroscience community has lost a dear friend and mentor. Ed Kravitz passed away on Sunday, September 21, 2025.
Here he is this past summer speaking with (and making margaritas for) the 2025 Grass Fellows, as he's done for more than two decades.
Rest in peace.
Here he is this past summer speaking with (and making margaritas for) the 2025 Grass Fellows, as he's done for more than two decades.
Rest in peace.
September 24, 2025 at 6:03 PM
The neuroscience community has lost a dear friend and mentor. Ed Kravitz passed away on Sunday, September 21, 2025.
Here he is this past summer speaking with (and making margaritas for) the 2025 Grass Fellows, as he's done for more than two decades.
Rest in peace.
Here he is this past summer speaking with (and making margaritas for) the 2025 Grass Fellows, as he's done for more than two decades.
Rest in peace.
Reposted by Caroline Fecher
Reposted by Caroline Fecher
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
September 17, 2025 at 5:38 PM
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
Reposted by Caroline Fecher
Now accepting applications for the 2026 Grass Fellowship!
Do you have a great idea for a project you can do next summer in the Grass Lab at the @mblscience.bsky.social?
Get working on that proposal!
grassfoundation.org/apply-for-th...
Do you have a great idea for a project you can do next summer in the Grass Lab at the @mblscience.bsky.social?
Get working on that proposal!
grassfoundation.org/apply-for-th...
September 2, 2025 at 8:42 PM
Now accepting applications for the 2026 Grass Fellowship!
Do you have a great idea for a project you can do next summer in the Grass Lab at the @mblscience.bsky.social?
Get working on that proposal!
grassfoundation.org/apply-for-th...
Do you have a great idea for a project you can do next summer in the Grass Lab at the @mblscience.bsky.social?
Get working on that proposal!
grassfoundation.org/apply-for-th...
Reposted by Caroline Fecher
#Throwback 🧪
COMMENT | A brief guide to studying extracellular vesicle function in the context of metabolism
C Crewe et al
COMMENT | A brief guide to studying extracellular vesicle function in the context of metabolism
C Crewe et al
A brief guide to studying extracellular vesicle function in the context of metabolism - Nature Metabolism
Extracellular vesicles (EVs) are now recognized as powerful modulators of metabolism, and thus the new field of EV-mediated metabolic regulation is growing exponentially. Here, we discuss special experimental considerations for the study of EV function in metabolism.
bit.ly
August 20, 2025 at 3:21 PM
#Throwback 🧪
COMMENT | A brief guide to studying extracellular vesicle function in the context of metabolism
C Crewe et al
COMMENT | A brief guide to studying extracellular vesicle function in the context of metabolism
C Crewe et al
Reposted by Caroline Fecher
📣It’s TIIIIIIIMMMMEEEEE!
Presenting authors of submitted abstracts have been notified of their acceptance status.
Drop a comment below or tag us in your post so we can join in on the excitement. 🧠
#neurosky #neuroskyence #SfN25
#academicsky #scisky
Presenting authors of submitted abstracts have been notified of their acceptance status.
Drop a comment below or tag us in your post so we can join in on the excitement. 🧠
#neurosky #neuroskyence #SfN25
#academicsky #scisky
August 5, 2025 at 4:29 PM
📣It’s TIIIIIIIMMMMEEEEE!
Presenting authors of submitted abstracts have been notified of their acceptance status.
Drop a comment below or tag us in your post so we can join in on the excitement. 🧠
#neurosky #neuroskyence #SfN25
#academicsky #scisky
Presenting authors of submitted abstracts have been notified of their acceptance status.
Drop a comment below or tag us in your post so we can join in on the excitement. 🧠
#neurosky #neuroskyence #SfN25
#academicsky #scisky
Reposted by Caroline Fecher
Our latest review is out in STEM CELLS!
We discuss the role of mitochondria in neuronal branching and how iPSC models in 2D and 3D can be used dissect the impact of neuronal branching defects in mitochondrial disorders.
academic.oup.com/stmcls/advan...
We discuss the role of mitochondria in neuronal branching and how iPSC models in 2D and 3D can be used dissect the impact of neuronal branching defects in mitochondrial disorders.
academic.oup.com/stmcls/advan...
Neuronal branching in stem cell models of mitochondrial and neurological diseases
Abstract. Neuronal branching, the extension and arborization of neurites, is critical for establishing and maintaining functional neural circuits. Emerging
academic.oup.com
July 23, 2025 at 5:05 PM
Our latest review is out in STEM CELLS!
We discuss the role of mitochondria in neuronal branching and how iPSC models in 2D and 3D can be used dissect the impact of neuronal branching defects in mitochondrial disorders.
academic.oup.com/stmcls/advan...
We discuss the role of mitochondria in neuronal branching and how iPSC models in 2D and 3D can be used dissect the impact of neuronal branching defects in mitochondrial disorders.
academic.oup.com/stmcls/advan...
Reposted by Caroline Fecher
Very excited to share my postdoc work- out now at PNAS!
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
July 7, 2025 at 7:38 PM
Very excited to share my postdoc work- out now at PNAS!
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
Reposted by Caroline Fecher
Reposted by Caroline Fecher
We're hiring! The Journal of Cell Biology (JCB) seeks Scientific Editor or Senior Scientific Editor, dependent on experience. Join our team in New York City! Apply here 👉 careers.rockefeller.edu/jobs?keyword...
#STEMjobs #LifeScienceJobs #PublishingJobs #ScienceJobs
#STEMjobs #LifeScienceJobs #PublishingJobs #ScienceJobs
June 5, 2025 at 8:16 PM
We're hiring! The Journal of Cell Biology (JCB) seeks Scientific Editor or Senior Scientific Editor, dependent on experience. Join our team in New York City! Apply here 👉 careers.rockefeller.edu/jobs?keyword...
#STEMjobs #LifeScienceJobs #PublishingJobs #ScienceJobs
#STEMjobs #LifeScienceJobs #PublishingJobs #ScienceJobs
Reposted by Caroline Fecher
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mitochondrial presequences harbor variable strengths to maintain organellar function
Hundreds of mitochondrial-destined proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphipathic helices, presequences lack ...
www.biorxiv.org
May 29, 2025 at 9:18 PM
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Caroline Fecher
Looking for some good news today?
We have eight inspiring early-career scientists heading to @mblscience.bsky.social to spend the summer conducting research on topics ranging from pain sensation in sharks to ocean acidification and behavior in sea slugs.
grassfoundation.org/announcing-t...
We have eight inspiring early-career scientists heading to @mblscience.bsky.social to spend the summer conducting research on topics ranging from pain sensation in sharks to ocean acidification and behavior in sea slugs.
grassfoundation.org/announcing-t...
May 22, 2025 at 5:08 PM
Looking for some good news today?
We have eight inspiring early-career scientists heading to @mblscience.bsky.social to spend the summer conducting research on topics ranging from pain sensation in sharks to ocean acidification and behavior in sea slugs.
grassfoundation.org/announcing-t...
We have eight inspiring early-career scientists heading to @mblscience.bsky.social to spend the summer conducting research on topics ranging from pain sensation in sharks to ocean acidification and behavior in sea slugs.
grassfoundation.org/announcing-t...
Reposted by Caroline Fecher
Great study by @nataliabaumann.bsky.social @djabaudon.bsky.social & collaborators, showing how regional differences in progenitor metabolism shape brain growth during development
@cp-cell.bsky.social
www.cell.com/cell/abstrac...
@cp-cell.bsky.social
www.cell.com/cell/abstrac...
Regional differences in progenitor metabolism shape brain growth during development
Brain-wide birthdate mapping reveals that while hindbrain neurogenesis is transient,
forebrain neurogenesis is temporally sustained through spatiotemporal regulation of
progenitor mitochondrial functi...
www.cell.com
May 1, 2025 at 2:11 PM
Great study by @nataliabaumann.bsky.social @djabaudon.bsky.social & collaborators, showing how regional differences in progenitor metabolism shape brain growth during development
@cp-cell.bsky.social
www.cell.com/cell/abstrac...
@cp-cell.bsky.social
www.cell.com/cell/abstrac...
Reposted by Caroline Fecher
🚨 pleased to share a new preprint made possible through a fantastic collaboration with the Skala & Palecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy & Aaron co-led efforts to tackle this question w/HPLM! tinyurl.com/ux2arjw8
Human Plasma-Like Medium Promotes Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes
Maturing human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) in vitro is critical for advancing drug discovery and cardiotoxicity screening applications of these cells. However, the metaboli...
tinyurl.com
April 28, 2025 at 4:02 PM
🚨 pleased to share a new preprint made possible through a fantastic collaboration with the Skala & Palecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy & Aaron co-led efforts to tackle this question w/HPLM! tinyurl.com/ux2arjw8
Reposted by Caroline Fecher
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress
Quantitative imaging of the mitochondrial central dogma identifies translation hubs that are suppressed during stress.
www.science.org
April 18, 2025 at 10:39 PM
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Reposted by Caroline Fecher
Niemi lab and @washubbsb.bsky.social graduate student Youmian Yan gave a fantastic presentation on her work at the @asbmb.bsky.social meeting in Chicago! #ProudPI (photo credit to @kerikozul.bsky.social)
April 14, 2025 at 4:13 PM
Niemi lab and @washubbsb.bsky.social graduate student Youmian Yan gave a fantastic presentation on her work at the @asbmb.bsky.social meeting in Chicago! #ProudPI (photo credit to @kerikozul.bsky.social)