Sara Nowinski
@saranowinski.bsky.social
Assistant Professor at the Van Andel Institute. Alum of: Rutter Lab, UT Austin, Carleton College. Love mitochondria, my girls, running, good food & good friends.
Whoo hoo! The final version of our first paper is online! So proud of the team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Redirecting
kwnsfk27.r.eu-west-1.awstrack.me
October 10, 2025 at 4:47 PM
Whoo hoo! The final version of our first paper is online! So proud of the team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Reposted by Sara Nowinski
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
@uofunuip.bsky.social
Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
www.nature.com
August 27, 2025 at 11:05 PM
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
@uofunuip.bsky.social
Reposted by Sara Nowinski
Abstracts for Midwest Metabolism / TriMAD meeting are due Sept 8! That’s 2 weeks away folks! Join us in Ann Arbor this fall. www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
August 18, 2025 at 3:40 PM
Abstracts for Midwest Metabolism / TriMAD meeting are due Sept 8! That’s 2 weeks away folks! Join us in Ann Arbor this fall. www.vai.org/event/2025-m...
Abstracts for Midwest Metabolism / TriMAD meeting are due Sept 8! That’s 2 weeks away folks! Join us in Ann Arbor this fall. www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
August 18, 2025 at 3:40 PM
Abstracts for Midwest Metabolism / TriMAD meeting are due Sept 8! That’s 2 weeks away folks! Join us in Ann Arbor this fall. www.vai.org/event/2025-m...
Reposted by Sara Nowinski
I’m really beyond thrilled to be included in this years Pew Biomedical Scholars cohort and to be able to meet all the incredible scientists in this program. I was in Scott Kennedy’s lab when he was a Pew Scholar and never thought I’d be lucky enough to also be one! www.pew.org/en/about/new...
Pew Awards 22 Researchers Biomedical Science Grants
www.pew.org
August 12, 2025 at 3:41 PM
I’m really beyond thrilled to be included in this years Pew Biomedical Scholars cohort and to be able to meet all the incredible scientists in this program. I was in Scott Kennedy’s lab when he was a Pew Scholar and never thought I’d be lucky enough to also be one! www.pew.org/en/about/new...
6 weeks left to submit your abstract for Midwest Metabolism & TRiMAD 2025! Join us in Ann Arbor this fall!!! www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
July 21, 2025 at 2:45 PM
6 weeks left to submit your abstract for Midwest Metabolism & TRiMAD 2025! Join us in Ann Arbor this fall!!! www.vai.org/event/2025-m...
Reposted by Sara Nowinski
Officially tenured. Thank you to all the mentors who guided me, and to the trainees who made this possible with your ideas, hard work, and scientific joy.
July 10, 2025 at 5:44 PM
Officially tenured. Thank you to all the mentors who guided me, and to the trainees who made this possible with your ideas, hard work, and scientific joy.
Reposted by Sara Nowinski
Spread the word - Join us! We’re hiring an assistant professor/investigator to lead a metabolism-focused research program @morgridgemeta.bsky.social in partnership with @bmolchem.bsky.social for tenure track position at @uwmadison.bsky.social. To learn more & to apply: morgridge.org/job-posting/...
Assistant Professor in Metabolism Research - Morgridge Institute for Research
The Morgridge Institute for Research, in partnership with the Department of Biomolecular Chemistry at the University of Wisconsin-Madison, seeks a joint tenure track assistant professor to lead a vibr...
morgridge.org
July 11, 2025 at 10:20 AM
Spread the word - Join us! We’re hiring an assistant professor/investigator to lead a metabolism-focused research program @morgridgemeta.bsky.social in partnership with @bmolchem.bsky.social for tenure track position at @uwmadison.bsky.social. To learn more & to apply: morgridge.org/job-posting/...
Reposted by Sara Nowinski
For ESIs dealing with grants being rescinded: if an investigator’s 1st substantial independent research award is terminated within the first 3 years of the project period (not due to scientific misconduct ) they can request the reinstatement of ESI status
grants.nih.gov/news-events/...
grants.nih.gov/news-events/...
July 2, 2025 at 7:27 PM
For ESIs dealing with grants being rescinded: if an investigator’s 1st substantial independent research award is terminated within the first 3 years of the project period (not due to scientific misconduct ) they can request the reinstatement of ESI status
grants.nih.gov/news-events/...
grants.nih.gov/news-events/...
Reposted by Sara Nowinski
Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
June 4, 2025 at 6:21 PM
Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...
Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
June 4, 2025 at 6:21 PM
Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...
Reposted by Sara Nowinski
I'm excited to share our latest story from the
@lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
@lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
Intracellular metabolic gradients dictate dependence on exogenous pyruvate
Nature Metabolism - Jackson et al. provide insight into how metabolic adaptations that accompany cell state transitions drive reliance on exogenous nutrient availability, focusing on pyruvate as a...
rdcu.be
April 28, 2025 at 2:28 PM
I'm excited to share our latest story from the
@lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
@lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
Reposted by Sara Nowinski
Intracellular metabolic gradients dictate dependence on exogenous pyruvate
www.nature.com/articles/s42...
Congrats to @lydiafinley.bsky.social Lab!
www.nature.com/articles/s42...
Congrats to @lydiafinley.bsky.social Lab!
Intracellular metabolic gradients dictate dependence on exogenous pyruvate - Nature Metabolism
Jackson et al. provide insight into how metabolic adaptations that accompany cell state transitions drive reliance on exogenous nutrient availability, focusing on pyruvate as a key metabolite in centr...
www.nature.com
April 29, 2025 at 5:42 AM
Intracellular metabolic gradients dictate dependence on exogenous pyruvate
www.nature.com/articles/s42...
Congrats to @lydiafinley.bsky.social Lab!
www.nature.com/articles/s42...
Congrats to @lydiafinley.bsky.social Lab!
Very cool!!
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress
Quantitative imaging of the mitochondrial central dogma identifies translation hubs that are suppressed during stress.
www.science.org
April 20, 2025 at 2:13 AM
Very cool!!
Reposted by Sara Nowinski
Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell!
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis
Mitochondria serve as central hubs in cellular metabolism by sensing, integrating, and responding to metabolic demands. This integrative function is a…
www.sciencedirect.com
April 17, 2025 at 9:24 PM
Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell!
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
Reposted by Sara Nowinski
I'm excited to present my work on the deorphanization of atypical lipid catabolic enzymes at #ASBMB25 on Monday April 14th. Please come to W179 to hear my flash-talk at 9:30AM and hang out with me at poster #350! #lipidtime
April 12, 2025 at 8:58 PM
I'm excited to present my work on the deorphanization of atypical lipid catabolic enzymes at #ASBMB25 on Monday April 14th. Please come to W179 to hear my flash-talk at 9:30AM and hang out with me at poster #350! #lipidtime
Reposted by Sara Nowinski
Registration is live for the 1st ever Midwest Metabolism & TRiMAD dual meeting, hosted jointly by VAI + U of M in Ann Arbor, MI November 10-11, 2025! We have some exciting speakers but most will come from abstracts so submit your best #mitochondria & #metabolism research! www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
March 29, 2025 at 8:38 PM
Registration is live for the 1st ever Midwest Metabolism & TRiMAD dual meeting, hosted jointly by VAI + U of M in Ann Arbor, MI November 10-11, 2025! We have some exciting speakers but most will come from abstracts so submit your best #mitochondria & #metabolism research! www.vai.org/event/2025-m...
Registration is live for the 1st ever Midwest Metabolism & TRiMAD dual meeting, hosted jointly by VAI + U of M in Ann Arbor, MI November 10-11, 2025! We have some exciting speakers but most will come from abstracts so submit your best #mitochondria & #metabolism research! www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
March 29, 2025 at 8:38 PM
Registration is live for the 1st ever Midwest Metabolism & TRiMAD dual meeting, hosted jointly by VAI + U of M in Ann Arbor, MI November 10-11, 2025! We have some exciting speakers but most will come from abstracts so submit your best #mitochondria & #metabolism research! www.vai.org/event/2025-m...
Reposted by Sara Nowinski
I’m going to staple these peeves to my door just so my students know it’s not just me.
I have several scientific pet peeves: Comic sans in presentations, "statistically significant" differences that aren't substantially different, and GO terms. They can be misleading and are often so broad as to be meaningless.
GO Team: Hold my beer. GO big or GO home.
www.nature.com/articles/s41...
GO Team: Hold my beer. GO big or GO home.
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
February 28, 2025 at 2:21 AM
I’m going to staple these peeves to my door just so my students know it’s not just me.
I’ve had such a great few days of science and sunshine thanks to @fusionconf.bsky.social !! Super big congrats to lab postdoc Sam Preston who won a poster award!! Many thanks to the organizers for an awesome meeting.
February 26, 2025 at 6:29 PM
I’ve had such a great few days of science and sunshine thanks to @fusionconf.bsky.social !! Super big congrats to lab postdoc Sam Preston who won a poster award!! Many thanks to the organizers for an awesome meeting.
Reposted by Sara Nowinski
Next, our 2nd preprint of the week (!), this one driven by @madelouhart.bsky.social
Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability.
Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!
Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability.
Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!
Succinate Dehydrogenase loss causes cascading metabolic effects that impair pyrimidine biosynthesis https://www.biorxiv.org/content/10.1101/2025.02.18.638948v1
February 20, 2025 at 10:25 PM
Next, our 2nd preprint of the week (!), this one driven by @madelouhart.bsky.social
Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability.
Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!
Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability.
Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!
Reposted by Sara Nowinski
Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside:
A broadly applicable serum-free media,
Quantitative lipid uptake characterization,
Evidence lipid scavenging > synthesis for cancer cell proliferation.
A broadly applicable serum-free media,
Quantitative lipid uptake characterization,
Evidence lipid scavenging > synthesis for cancer cell proliferation.
Defined media reveals the essential role of lipid scavenging to support cancer cell proliferation https://www.biorxiv.org/content/10.1101/2025.02.12.637975v1
February 20, 2025 at 2:43 AM
Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside:
A broadly applicable serum-free media,
Quantitative lipid uptake characterization,
Evidence lipid scavenging > synthesis for cancer cell proliferation.
A broadly applicable serum-free media,
Quantitative lipid uptake characterization,
Evidence lipid scavenging > synthesis for cancer cell proliferation.
Reposted by Sara Nowinski
excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!
Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1
February 10, 2025 at 6:40 PM
excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!