Israel has claimed they were striking militant targets in northern Gaza in their latest attack.

Abstract. T cell tolerance to self can prevent self-reactive B cells from mounting effective autoimmune responses by limiting their available help. However

Tom Fletcher says five aid trucks allowed into Gaza yesterday have not yet reached people, as the UK, France and Canada threaten action against Israel.

The effect of Israel’s total siege has become “catastrophic,” doctors say. Food, water and medicine shortages are prompting a surge of preventable illnesses, and deaths.

Vaccines generate long-lived plasma cells and memory B cells (Bmems) that may re-enter secondary germinal centers (GCs) to further mutate their B cell…

The lungs are constantly exposed to the external environment and a myriad of antigenic challenges within the air. Chronic exposure to allergens and...

Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...

imageimageSubcutaneous infection by lymphocytic choriomeningitis virus (LCMV) is characterized by skewed CD4+ T-cell polarization, as well as severely impaired differentiation of T follicular helper (...

Molinos-Albert et al. developed an integrative analysis of SARS-CoV-2 antibody B-cell responses in a cohort of 113 healthcare workers followed since the beginning of the pandemic during a 3-year period. The authors report that despite differential kinetics, COVID-19-recovered and -naive individuals developed comparable and long-lasting immunity.

B cells that give rise to neutralizing antibody responses can be extremely rare in the naive B cell repertoire. Madden et al. show that delivery strategy and adjuvant selection affect the recruitment and expansion of rare broadly neutralizing antibody-precursor B cells after immunization with an HIV germline-targeting vaccine and that antibody feedback appears to substantially influence the boosting response.