Ella Hartenian
@ehartenian.bsky.social
Herpesvirologist and immunologist. EMBO Postdoc w Petr Broz in Lausanne | previously PhD with Britt Glaunsinger @UCBerkekey
Annndddd it’s out! Here’s what came out of combining my virology background with the @brozlab.bsky.social’s cell death focus : a novel role for the cell death protein ninj1 during hsv1 infection. In brief, Ninj1 on mouse macrophages results in lower infection rates and higher cytokine secretion.
November 20, 2025 at 3:29 PM
Annndddd it’s out! Here’s what came out of combining my virology background with the @brozlab.bsky.social’s cell death focus : a novel role for the cell death protein ninj1 during hsv1 infection. In brief, Ninj1 on mouse macrophages results in lower infection rates and higher cytokine secretion.
Reposted by Ella Hartenian
November is a big month for the lab with *two* new papers by @ehartenian.bsky.social and @alexandraboegli.bsky.social ++ co authors now online.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
NINJ1 blocks HSV-1 entry into macrophages to impact viral replication and immunity | EMBO reports
imageimageNINJ1 blocks HSV-1 entry into mouse macrophages independent of its role in cell death, resulting in greater secretion of pro inflammatory cytokines downstream of infection. Mouse macrophages lacking NINJ1 are more permissive to HSV-1 ...
www.embopress.org
November 20, 2025 at 3:15 PM
November is a big month for the lab with *two* new papers by @ehartenian.bsky.social and @alexandraboegli.bsky.social ++ co authors now online.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Reposted by Ella Hartenian
It’s DIB day! The annual conference for our department @dib-unil.bsky.social. Lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @elliottbernard.bsky.social 🔬!
November 11, 2025 at 1:21 PM
It’s DIB day! The annual conference for our department @dib-unil.bsky.social. Lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @elliottbernard.bsky.social 🔬!
Reposted by Ella Hartenian
Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne!
@brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social
@brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social
October 1, 2025 at 9:30 AM
Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne!
@brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social
@brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social
Reposted by Ella Hartenian
No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org
July 22, 2025 at 8:58 PM
No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org
Reposted by Ella Hartenian
📣Save the date! 📣
We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year.
We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!
We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year.
We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!
May 26, 2025 at 9:24 AM
📣Save the date! 📣
We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year.
We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!
We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year.
We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!
Reposted by Ella Hartenian
🚨 URGENT RESPONSE CALL 🚨
Trump’s Fool’s Gold Science EO is a dangerous sham.
It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda.
We’ve launched an open letter.
SIGN & SHARE NOW: actionnetwork.org/petitions/op...
Trump’s Fool’s Gold Science EO is a dangerous sham.
It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda.
We’ve launched an open letter.
SIGN & SHARE NOW: actionnetwork.org/petitions/op...
Sign The Open Letter to Stand Up For Science Now!
Science is under siege. Trump’s latest Executive Order calls for politically appointed science commissars to evaluate research. Join us in adding your name to our open letter condemning Trump’s escala...
actionnetwork.org
May 26, 2025 at 4:19 PM
🚨 URGENT RESPONSE CALL 🚨
Trump’s Fool’s Gold Science EO is a dangerous sham.
It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda.
We’ve launched an open letter.
SIGN & SHARE NOW: actionnetwork.org/petitions/op...
Trump’s Fool’s Gold Science EO is a dangerous sham.
It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda.
We’ve launched an open letter.
SIGN & SHARE NOW: actionnetwork.org/petitions/op...
Reposted by Ella Hartenian
A new combination of microscopy methods has revealed exquisite details of the virus assembly process used by herpes simplex virus during replication.
buff.ly/aO8W9BJ
buff.ly/aO8W9BJ
March 27, 2025 at 11:01 AM
A new combination of microscopy methods has revealed exquisite details of the virus assembly process used by herpes simplex virus during replication.
buff.ly/aO8W9BJ
buff.ly/aO8W9BJ
Reposted by Ella Hartenian
Our research shows that ~50% of mothers globally decline at least half of opportunities to participate in conferences after becoming parents (N=3995). We understand the barriers and are offering Travel Grants to help overcome these challenges.
Apply now - deadline 31st March!
shorturl.at/gnCU2
Apply now - deadline 31st March!
shorturl.at/gnCU2
March 18, 2025 at 11:25 AM
Our research shows that ~50% of mothers globally decline at least half of opportunities to participate in conferences after becoming parents (N=3995). We understand the barriers and are offering Travel Grants to help overcome these challenges.
Apply now - deadline 31st March!
shorturl.at/gnCU2
Apply now - deadline 31st March!
shorturl.at/gnCU2
Reposted by Ella Hartenian
Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
First authors Madeline Churchill and Ankit Pandeya @nkeet50.bsky.social from @rauchlab.bsky.social show that tuft cells, known for their role in anti-parasite defenses, can also contribute to anti-bacterial responses in the small intestine. rupress.org/jem/article/...
#InfectiousDisease
#InfectiousDisease
March 13, 2025 at 4:31 PM
Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
Reposted by Ella Hartenian
I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...
January 29, 2025 at 7:14 AM
I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...
Reposted by Ella Hartenian
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
March 6, 2025 at 7:14 PM
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
Reposted by Ella Hartenian
Get in Dorks, we are going protesting.
STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS.
More information to come.
STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS.
More information to come.
February 9, 2025 at 2:23 PM
Get in Dorks, we are going protesting.
STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS.
More information to come.
STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS.
More information to come.
Reposted by Ella Hartenian
NYGC is organizing a number of efforts to address the changes to NIH IDCs and other changes to federal policy. If you are a US citizen, or in the US working in science, please consider signing this petition. The more signatures the stronger our hand in interacting with law makers. chng.it/kK2HMP5pGk
Sign the Petition
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
chng.it
February 10, 2025 at 3:42 PM
NYGC is organizing a number of efforts to address the changes to NIH IDCs and other changes to federal policy. If you are a US citizen, or in the US working in science, please consider signing this petition. The more signatures the stronger our hand in interacting with law makers. chng.it/kK2HMP5pGk
Reposted by Ella Hartenian
Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences.
Every Friday, I debrief you over a drink at
buttondown.com/liminalcreat...
Every Friday, I debrief you over a drink at
buttondown.com/liminalcreat...
Making Sense of It All
Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...
buttondown.com
February 1, 2025 at 3:59 PM
Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences.
Every Friday, I debrief you over a drink at
buttondown.com/liminalcreat...
Every Friday, I debrief you over a drink at
buttondown.com/liminalcreat...
The excellent Swiss Virology Meeting just ended. Thanks to the organizers and participants for making it such a warm and collegial environment. Here Magalie and I are with the project that began as her masters project. 🦠🚀
January 29, 2025 at 4:10 PM
The excellent Swiss Virology Meeting just ended. Thanks to the organizers and participants for making it such a warm and collegial environment. Here Magalie and I are with the project that began as her masters project. 🦠🚀
Reposted by Ella Hartenian
Happy to share the first preprint from my lab by
@indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity!
Check out Indra’s thread for a summary:
@indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity!
Check out Indra’s thread for a summary:
I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...
January 29, 2025 at 1:57 PM
Happy to share the first preprint from my lab by
@indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity!
Check out Indra’s thread for a summary:
@indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity!
Check out Indra’s thread for a summary:
Reposted by Ella Hartenian
We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland.
Registrations open March 1 - Attendance limited to 150 participants.
More info: wp.unil.ch/immunobiolog...
#ImmunoSky
Registrations open March 1 - Attendance limited to 150 participants.
More info: wp.unil.ch/immunobiolog...
#ImmunoSky
Symposium immunobiology
wp.unil.ch
January 28, 2025 at 2:33 PM
We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland.
Registrations open March 1 - Attendance limited to 150 participants.
More info: wp.unil.ch/immunobiolog...
#ImmunoSky
Registrations open March 1 - Attendance limited to 150 participants.
More info: wp.unil.ch/immunobiolog...
#ImmunoSky
Reposted by Ella Hartenian
Check out our latest pre print! Alexandra and colleagues show that the enigmatic inflammasome receptor, NLRP6 is activated by sterile and pathogen induced endolysosomal damage. Hot off the press!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Sterile- or pathogen-induced endolysosomal damage activate the NLRP6 inflammasome in human intestinal epithelial cells
NLRP6 controls host defense against bacteria and viruses in the gastrointestinal tract by a poorly understood mechanism. Here, we report that NLRP6 forms an inflammasome upon endolysosomal damage caus...
www.biorxiv.org
January 28, 2025 at 1:42 PM
Check out our latest pre print! Alexandra and colleagues show that the enigmatic inflammasome receptor, NLRP6 is activated by sterile and pathogen induced endolysosomal damage. Hot off the press!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ella Hartenian
For those who haven't been following the cozying up to RFK Jr. by some liberals (call them what you want, they are not Republicans) and why it's dangerous. Three pieces to lay out the case. 1/
January 4, 2025 at 11:09 AM
For those who haven't been following the cozying up to RFK Jr. by some liberals (call them what you want, they are not Republicans) and why it's dangerous. Three pieces to lay out the case. 1/
Reposted by Ella Hartenian
The class gap in career progression: US academia
First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree.
mitsloan.mit.edu/shared/ods/d...
First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree.
mitsloan.mit.edu/shared/ods/d...
December 28, 2024 at 10:58 AM
The class gap in career progression: US academia
First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree.
mitsloan.mit.edu/shared/ods/d...
First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree.
mitsloan.mit.edu/shared/ods/d...
Reposted by Ella Hartenian
MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures
With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly
www.eurekalert.org/news-release...
With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly
www.eurekalert.org/news-release...
MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures
Researchers in the MIT Jameel Clinic for Machine Learning in Health developed a fully open-source biomolecular structure prediction model that achieves state-of-the-art performance, at the level of Al...
www.eurekalert.org
December 22, 2024 at 5:33 PM
MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures
With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly
www.eurekalert.org/news-release...
With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly
www.eurekalert.org/news-release...
Reposted by Ella Hartenian
A new genomic study in Science encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neanderthal gene flow into early modern humans left an indelible mark on human evolution. scim.ag/4gkMvpz
Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans
Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 year...
scim.ag
December 17, 2024 at 5:55 PM
A new genomic study in Science encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neanderthal gene flow into early modern humans left an indelible mark on human evolution. scim.ag/4gkMvpz
Reposted by Ella Hartenian
It's that time of year. Confocal + Christmas = Xmas Tree, Ymas Tree, and our favorite Zmas tree. #microscopy #confocal #imaging
December 11, 2024 at 7:04 PM
It's that time of year. Confocal + Christmas = Xmas Tree, Ymas Tree, and our favorite Zmas tree. #microscopy #confocal #imaging
Reposted by Ella Hartenian
Interested in learning more about NINJ1? My colleagues in the @brozlab.bsky.social, including @ehartenian.bsky.social, wrote a nice review of our current knowledge. www.cell.com/trends/bioch...
www.cell.com
December 5, 2024 at 6:18 AM
Interested in learning more about NINJ1? My colleagues in the @brozlab.bsky.social, including @ehartenian.bsky.social, wrote a nice review of our current knowledge. www.cell.com/trends/bioch...