David Huang
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dcshuang.bsky.social
David Huang
@dcshuang.bsky.social
200 followers 390 following 2 posts
Biomedical researcher at WEHI. BCL2, mitochondria, apoptosis and targeted therapies for leukemias/lymphomas.
Posts Replies Media Videos
Reposted by David Huang
wehi-research.bsky.social
We’re incredibly proud to share Professor Peter Gibbs has been elected a Fellow of the Australian Academy of Health and Medical Sciences 👏 🎉

He is one of 29 new AAHMS Fellows to be recognised for outstanding contributions towards medical research.

www.wehi.edu.au/news/cancer-...
October 28, 2025 at 11:12 PM
Reposted by David Huang
wehi-research.bsky.social
🎓 Applications are now open for WEHI’s International PhD Scholar Initiative.

📅 Apply by Sunday 26 October 2025

🔗 Learn more about eligibility, scholarships and how to apply: wehi.edu.au/education/ph...

Help us spread the word by sharing with your networks!
September 10, 2025 at 2:08 AM
Reposted by David Huang
wehi-research.bsky.social
Researchers from WEHI’s Parkinson Disease Research Centre have won the 2025 UNSW Eureka Prize for Scientific Research. The team has been honoured for their research unravelling how PINK1, a key protein linked to early-onset Parkinson’s disease, works.

🔗 www.wehi.edu.au/news/eureka-...
📸 L–R: Professor David Komander, Dr Nicholas Kirk, Dr Sylvie Callegari and Dr Alisa Glukhova. 
September 3, 2025 at 9:54 PM
Reposted by David Huang
science.org.au
In Canberra's iconic Shine Dome, we are witnessing the recognition of Australia's brightest scientific minds. Following the 2025 election of new Fellows (pictured), the total Fellowship stands at 630 Fellows.
🎥 Don't miss the live stream of their presentations! https://bit.ly/SATS-25
Group of people posing for a photo in front of the dark, dome-shaped building of the Australian Academy of Science, known as the Shine Dome, in Canberra. A group of people gathered around a food truck beside a tent at an outdoor event near a drained pool. The setting includes a mix of trees and cloud-filled sky. A group of individuals networking at a corporate event, discussing near a table with fresh oranges while a demonstration is shown on a screen above.
September 2, 2025 at 1:19 AM
dcshuang.bsky.social
Clare Scott inducted as Fellow of the Australian Academy of Science #ShineDome25 @wehi-research.bsky.social @science.org.au
September 2, 2025 at 12:17 AM
Reposted by David Huang
wehi-research.bsky.social
Researchers from WEHI, the Royal Melbourne Hospital & @petermaccc.bsky.social have achieved a brain cancer clinical trial world-first, providing hope to patients with low-grade gliomas.

🔗 www.wehi.edu.au/news/world-f...
The BrainPOP research team (left to right): Professor Kate Drummond, Dr Jim Whittle, Dr Saskia Freytag, Dr Sarah Best
August 22, 2025 at 10:31 PM
Reposted by David Huang
wehi-research.bsky.social
Using spatial technology, WEHI researchers have mapped the bone marrow in unprecedented detail – showing how myeloma behaves differently in each patient. A step toward personalised blood cancer treatment.

🔗 www.wehi.edu.au/news/rethink...

@bloodjournals.hematology.org
The first detailed molecular map of human bone marrow, created by WEHI researchers using state-of-the-art spatial technology, with each colour representing a different cell type.
August 17, 2025 at 11:10 PM
Reposted by David Huang
proftomellis.bsky.social
Would you pay $150 per article to post your preprint on @bioRxiv @aRxiv @medRxiv @chemRxiv etc.? Currently it’s free but a small cost could help offset running costs and also work as a barrier against paper mills and AIs just posting all the time and filling these sites up.
July 9, 2025 at 6:03 PM
Reposted by David Huang
wehi-research.bsky.social
New research: MCL-1 not only prevents cell death, also fuels cells by supporting energy production. Helps explain side effects seen with MCL-1 targeting drugs in cancer clinical trials; could lead to better therapies. In @science.org

🔗 www.wehi.edu.au/news/hidden-...
Loss of MCL-1 triggers severe mitochondrial damage (shown in the right panel). Mitochondria are shown in red, cell nuclei in blue.
July 8, 2025 at 3:21 AM
Reposted by David Huang
mariolivio.bsky.social
Today is June 25. On this date in 1903 Marie Curie defended her doctoral thesis on radioactive substances at Université de la Sorbonne in Paris, becoming 1st woman in France to receive a doctoral degree. Image shows the thesis cover.
June 25, 2025 at 6:02 AM
Reposted by David Huang
mollygale.bsky.social
🧬🌽 Happy Transposon Day! 🌽🧬

Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
Barbara McClintock portrait
June 16, 2025 at 3:14 PM
Reposted by David Huang
jeremymberg.bsky.social
I showed my wife the graphic (which I fele is distressingly effective) and she made it worse...

"It looks like an apoptotic cell"

2/2
May 24, 2025 at 10:23 PM
Reposted by David Huang
wehi-research.bsky.social
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.

Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.

www.wehi.edu.au/news/fast-fo...
Innate lymphoid cells 3 (ILC3s) are a subset of immune cells that are critical to gut immunity. When there is excess fat, such as after a rich meal, ILC3s store this fat in tiny lipid droplets to maintain their function. In this 3D illustration, we can see a lipid droplet (in orange) inside an ILC3.
May 19, 2025 at 1:41 AM
Reposted by David Huang
shalinhnaik.bsky.social
A triumph of perseverance from twitterless Tom Weber, Christine Biben and the team, our in vivo barcoding "LoxCode mouse" used to resolve epiblast fate to fetal organs is finally published in @cellpress.bsky.social and available through @jacksonlab.bsky.social www.sciencedirect.com/science/arti...
LoxCode in vivo barcoding reveals epiblast clonal fate bias to fetal organs
Much remains to be learned about the clonal fate of mammalian epiblast cells. Here, we develop high-diversity Cre recombinase-driven LoxCode barcoding…
www.sciencedirect.com
May 16, 2025 at 4:32 AM
Reposted by David Huang
wehi-research.bsky.social
🌏 Make your mark in Melbourne! 🌏 We are looking for innovative researchers to join WEHI as Laboratory Heads and help lead the next wave of biomedical discovery.

For more information and to apply 👇
Make your future Melbourne
Lead the next wave of biomedical discovery
www.wehi.edu.au
May 15, 2025 at 7:03 AM
Reposted by David Huang
profsimonfisher.bsky.social
Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n
Four images to illustrate some prominent single-gene myths. Top left shows a photograph of a person deftly rolling their tongue into a U-shape. Top right shows a photograph of a person’s ear, highlighting the shape and features of the earlobe and cartilage. Bottom left shows a close-up photograph of a person’s eye, with a vivid blue colouration. Bottom right shows a photograph of a person poised to write with their left hand on the blank white page of a spiral-bound notebook.
May 2, 2025 at 2:50 PM
Reposted by David Huang
davekarpf.bsky.social
Remove a letter, ruin a movie.

Seeping Beauty
erikahall.bsky.social Erika Hall @erikahall.bsky.social · May 2
Remove a letter, ruin a movie.

Concave
mattneilhill.bsky.social Matt Neil Hill @mattneilhill.bsky.social · May 2
Remove a letter, ruin a movie.

The Cow.
May 2, 2025 at 10:33 PM
Reposted by David Huang
wehi-research.bsky.social
Researchers WEHI and Duke-NUS Medical School have uncovered another important role of protein MCL-1: it keeps hair growing!

A finding that could pave the way for new treatments for alopecia, hair loss.

Read the study in Nature Communications: www.nature.com/articles/s41...
March 25, 2025 at 11:26 PM
Reposted by David Huang
kaiming-l.bsky.social
Final version of our paper on targeting BAK / BAX to modulate apoptosis is out✌️! Can't wait to see where these tool compounds can be used💊. Honour to work in this team with screening scientists, chemists, biologists & more @dcshuang.bsky.social @dewsonlab.bsky.social @wehi-research.bsky.social
dewsonlab.bsky.social Dewson Lab @dewsonlab.bsky.social · Mar 9
www.science.org/doi/10.1126/...
Our new paper out now by Kaiming Li using a tool compound that highlights the coordination of BAX and BAK apoptotic activity through interaction with VDAC2 that may be targeted therapeutically.
Differential regulation of BAX and BAK apoptotic activity revealed by small molecules
Opposing regulation of BAX and BAK by VDAC2 dictates their role as executioners of apoptosis and their therapeutic targeting.
www.science.org
March 29, 2025 at 9:10 AM
Reposted by David Huang
wehi-research.bsky.social
World-first: researchers have discovered what protein #PINK1 looks like in humans and how it is activated, solving a decades-long mystery in the fight against #Parkinsonsdisease. The team hope to use the knowledge to find a drug to stop #Parkinsons.

www.wehi.edu.au/news/scienti...
Scientists solve decades-long Parkinson’s mystery
WEHI researchers have made a huge leap forward in the fight against Parkinson’s disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition.
www.wehi.edu.au
March 13, 2025 at 9:58 PM
Reposted by David Huang
sylviecallegari.bsky.social
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...

@wehi-research.bsky.social @komanderlab.bsky.social
March 13, 2025 at 7:20 PM