Daniel Gonzalez-Bohorquez
@dagozsci.bsky.social
EMBO Postdoctoral Fellow at the Arlotta Lab | Harvard Stem Cell and Regenerative Biology | alumni UZH | alumni UAM | 🇺🇸🇨🇭🇦🇺🇪🇸🇨🇴
--- Using brain organoids to understand brain disease ---
--- Using brain organoids to understand brain disease ---
Reposted by Daniel Gonzalez-Bohorquez
Congratulations @karalmckinley.bsky.social & lab on their groundbreaking recent preprint establishing + characterizing a chemically inducible model of menstruation in mouse:
www.biorxiv.org/content/10.1...
My jaw dropped when I heard this presented earlier this year. Incredible.
www.biorxiv.org/content/10.1...
My jaw dropped when I heard this presented earlier this year. Incredible.
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 9, 2025 at 10:59 PM
Congratulations @karalmckinley.bsky.social & lab on their groundbreaking recent preprint establishing + characterizing a chemically inducible model of menstruation in mouse:
www.biorxiv.org/content/10.1...
My jaw dropped when I heard this presented earlier this year. Incredible.
www.biorxiv.org/content/10.1...
My jaw dropped when I heard this presented earlier this year. Incredible.
Reposted by Daniel Gonzalez-Bohorquez
Actively hiring! Video made by Sora-2 but the job post is 100% real.
Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
October 2, 2025 at 7:49 PM
Actively hiring! Video made by Sora-2 but the job post is 100% real.
Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Reposted by Daniel Gonzalez-Bohorquez
Scripps Research Associate Prof. Xin Jin (@xinjin.bsky.social) has been named one of only 30 @hhmi.org Freeman Hrabowski Scholars, recognized for advancing genomic tools—including in vivo Perturb-seq—to map how genes shape brain circuits and uncover clues to neurological disease and brain health.
Scripps Research associate professor named an HHMI Freeman Hrabowski Scholar
www.scripps.edu
October 2, 2025 at 7:47 PM
Scripps Research Associate Prof. Xin Jin (@xinjin.bsky.social) has been named one of only 30 @hhmi.org Freeman Hrabowski Scholars, recognized for advancing genomic tools—including in vivo Perturb-seq—to map how genes shape brain circuits and uncover clues to neurological disease and brain health.
Reposted by Daniel Gonzalez-Bohorquez
💡I will be recruiting masters, PhD students and postdocs who are passionate about developmental neurobiology, tissue mechanics, imaging, and computational biology. If this excites you,, reach out to come build this new venture with me!
September 3, 2025 at 10:46 PM
💡I will be recruiting masters, PhD students and postdocs who are passionate about developmental neurobiology, tissue mechanics, imaging, and computational biology. If this excites you,, reach out to come build this new venture with me!
Reposted by Daniel Gonzalez-Bohorquez
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
September 3, 2025 at 10:43 PM
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
Reposted by Daniel Gonzalez-Bohorquez
New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social
Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics
Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...
www.biorxiv.org
September 3, 2025 at 12:19 PM
New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social
Reposted by Daniel Gonzalez-Bohorquez
New #cilia preprint alert
Our latest manuscript is now live on bioRxiv:
"The Neuronal Primary Cilium is a Key Regulator of Homeostatic Plasticity"
We hope you enjoy reading it!
www.biorxiv.org/content/10.1...
Our latest manuscript is now live on bioRxiv:
"The Neuronal Primary Cilium is a Key Regulator of Homeostatic Plasticity"
We hope you enjoy reading it!
www.biorxiv.org/content/10.1...
The Neuronal Primary Cilium is a Key Regulator of Homeostatic Plasticity
The capacity of neurons to maintain stable activity levels through homeostatic plasticity is essential for proper brain function. Primary cilia, which are non-motile, antenna-like organelles projectin...
www.biorxiv.org
September 1, 2025 at 10:12 PM
New #cilia preprint alert
Our latest manuscript is now live on bioRxiv:
"The Neuronal Primary Cilium is a Key Regulator of Homeostatic Plasticity"
We hope you enjoy reading it!
www.biorxiv.org/content/10.1...
Our latest manuscript is now live on bioRxiv:
"The Neuronal Primary Cilium is a Key Regulator of Homeostatic Plasticity"
We hope you enjoy reading it!
www.biorxiv.org/content/10.1...
Reposted by Daniel Gonzalez-Bohorquez
People with a psychiatric disorder are more likely to marry someone who has the same condition than to partner with someone who doesn’t
go.nature.com/3JGQlhf
go.nature.com/3JGQlhf
Spouses tend to share psychiatric disorders, massive study finds
Nature - Analysis of almost 15 million people shows the trend increases with each decade, across cultures and generations.
go.nature.com
August 31, 2025 at 12:45 PM
People with a psychiatric disorder are more likely to marry someone who has the same condition than to partner with someone who doesn’t
go.nature.com/3JGQlhf
go.nature.com/3JGQlhf
Reposted by Daniel Gonzalez-Bohorquez
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Daniel Gonzalez-Bohorquez
August 30, 2025 at 1:07 AM
Reposted by Daniel Gonzalez-Bohorquez
People with a psychiatric disorder are more likely to marry someone who has the same condition than to partner with someone who doesn’t
go.nature.com/4myGLvz
go.nature.com/4myGLvz
Spouses tend to share psychiatric disorders, massive study finds
Analysis of almost 15 million people shows the trend increases with each decade, across cultures and generations.
go.nature.com
August 29, 2025 at 1:14 PM
People with a psychiatric disorder are more likely to marry someone who has the same condition than to partner with someone who doesn’t
go.nature.com/4myGLvz
go.nature.com/4myGLvz
Reposted by Daniel Gonzalez-Bohorquez
🗺️🔬 A first-of-its-kind map of lipid traffic is demystifying an important yet elusive aspect of how cells work.
Read the study, out now in @nature.com, by Allen Distinguished Investigators Alf Honigmann, @nadlerlab.bsky.social, and collaborators: www.nature.com/articles/s41...
#FrontierScience
Read the study, out now in @nature.com, by Allen Distinguished Investigators Alf Honigmann, @nadlerlab.bsky.social, and collaborators: www.nature.com/articles/s41...
#FrontierScience
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
August 28, 2025 at 6:05 PM
🗺️🔬 A first-of-its-kind map of lipid traffic is demystifying an important yet elusive aspect of how cells work.
Read the study, out now in @nature.com, by Allen Distinguished Investigators Alf Honigmann, @nadlerlab.bsky.social, and collaborators: www.nature.com/articles/s41...
#FrontierScience
Read the study, out now in @nature.com, by Allen Distinguished Investigators Alf Honigmann, @nadlerlab.bsky.social, and collaborators: www.nature.com/articles/s41...
#FrontierScience
Reposted by Daniel Gonzalez-Bohorquez
Save the date and apply! We are organising another edition of the Monte Verità meeting “Neurogenesis from development to adulthood in health and disease”, March 30th to April 2nd 2026. Fantastic line up of speakers and beautiful setting! More details can be found here: neuro-unige.ch/news/csf-mee...
August 26, 2025 at 2:52 PM
Save the date and apply! We are organising another edition of the Monte Verità meeting “Neurogenesis from development to adulthood in health and disease”, March 30th to April 2nd 2026. Fantastic line up of speakers and beautiful setting! More details can be found here: neuro-unige.ch/news/csf-mee...
Reposted by Daniel Gonzalez-Bohorquez
Our latest: We developed a chemo-optogenetic system for precise spatiotemporal control of morphogen production. Using dual light + small molecule control of Sonic Hedgehog production, we recapitulated neural tube patterning in vitro & measured spread of Shh
🧵
www.sciencedirect.com/science/arti...
🧵
www.sciencedirect.com/science/arti...
Investigating morphogen and patterning dynamics with optogenetic control of morphogen production
Morphogen gradients provide the patterning cues that instruct cell fate decisions during development. Here, we establish an optogenetic system for the…
www.sciencedirect.com
August 26, 2025 at 8:28 AM
Our latest: We developed a chemo-optogenetic system for precise spatiotemporal control of morphogen production. Using dual light + small molecule control of Sonic Hedgehog production, we recapitulated neural tube patterning in vitro & measured spread of Shh
🧵
www.sciencedirect.com/science/arti...
🧵
www.sciencedirect.com/science/arti...
Reposted by Daniel Gonzalez-Bohorquez
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
August 21, 2025 at 8:16 PM
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
Reposted by Daniel Gonzalez-Bohorquez
We are proud to be a founding contributor to lipidinteractome.org, a repository developed by @tafesselab.bsky.social & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: arxiv.org/abs/2507.23101 #lipidtime
The Lipid Interactome Repository – Lipid Interactome Repository
lipidinteractome.org
August 5, 2025 at 1:06 PM
We are proud to be a founding contributor to lipidinteractome.org, a repository developed by @tafesselab.bsky.social & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: arxiv.org/abs/2507.23101 #lipidtime
Reposted by Daniel Gonzalez-Bohorquez
STAT's @matthewherper.bsky.social and @billgates.bsky.social have taken the stage!
Follow along here for live updates.
Join the event virtually: www.statnews.com/event/womens...
Follow along here for live updates.
Join the event virtually: www.statnews.com/event/womens...
August 4, 2025 at 9:16 PM
STAT's @matthewherper.bsky.social and @billgates.bsky.social have taken the stage!
Follow along here for live updates.
Join the event virtually: www.statnews.com/event/womens...
Follow along here for live updates.
Join the event virtually: www.statnews.com/event/womens...
Reposted by Daniel Gonzalez-Bohorquez
@billgates.bsky.social talks about the impacts of vaccine skepticism both in the U.S. and abroad.
August 4, 2025 at 11:20 PM
@billgates.bsky.social talks about the impacts of vaccine skepticism both in the U.S. and abroad.
Reposted by Daniel Gonzalez-Bohorquez
Gut-wrenching, surreal day in science. Gave a seminar at Harvard on the same day most investigators got NIH grant termination emails. Should I have paid for dinner?? I did try to be as entertaining as possible…
May 16, 2025 at 1:22 AM
Gut-wrenching, surreal day in science. Gave a seminar at Harvard on the same day most investigators got NIH grant termination emails. Should I have paid for dinner?? I did try to be as entertaining as possible…
Reposted by Daniel Gonzalez-Bohorquez
👏🏽 Big congrats to Costanza Borrelli who studied cell-cell interactions in the Lab of @andreasmoor.bsky.social, and Antonio Santinha from the lab of Randall Platt, inventor of a novel technology for single-cell CRISPR screening, received the 2024 #ETHmedals🤩
> u.ethz.ch/ZOnc3
@ethz.ch
> u.ethz.ch/ZOnc3
@ethz.ch
May 26, 2025 at 10:19 AM
👏🏽 Big congrats to Costanza Borrelli who studied cell-cell interactions in the Lab of @andreasmoor.bsky.social, and Antonio Santinha from the lab of Randall Platt, inventor of a novel technology for single-cell CRISPR screening, received the 2024 #ETHmedals🤩
> u.ethz.ch/ZOnc3
@ethz.ch
> u.ethz.ch/ZOnc3
@ethz.ch
Reposted by Daniel Gonzalez-Bohorquez
Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas.
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
May 14, 2025 at 5:24 PM
Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas.
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
Reposted by Daniel Gonzalez-Bohorquez
One of my images is featured in this stunning microscopy selection—what an honor!
Voting closes today, so check them out and pick your favorite!
#microscopy 🧪
focalplane.biologists.com/2025/03/11/v...
Voting closes today, so check them out and pick your favorite!
#microscopy 🧪
focalplane.biologists.com/2025/03/11/v...
Vote for your favourite image - FocalPlane
Vote for your favourite image - News
focalplane.biologists.com
March 26, 2025 at 8:27 AM
One of my images is featured in this stunning microscopy selection—what an honor!
Voting closes today, so check them out and pick your favorite!
#microscopy 🧪
focalplane.biologists.com/2025/03/11/v...
Voting closes today, so check them out and pick your favorite!
#microscopy 🧪
focalplane.biologists.com/2025/03/11/v...