Joanna Chustecki
@chusteckisci.bsky.social
Postdoc Associate at University of Oxford, currently studying mitochondrial dynamics in plant development
Also on the bird app
Also on the bird app
Reposted by Joanna Chustecki
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
November 20, 2025 at 11:42 AM
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
Reposted by Joanna Chustecki
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
September 22, 2025 at 6:27 PM
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
A privilege to attend the 9th annual Computational Plant Biology workshop last week at @slcuplants.bsky.social heard inspiring talks, got direct help and advice with pipeline bottlenecks and explored some very pretty places!
September 15, 2025 at 12:44 PM
A privilege to attend the 9th annual Computational Plant Biology workshop last week at @slcuplants.bsky.social heard inspiring talks, got direct help and advice with pipeline bottlenecks and explored some very pretty places!
Nice to see a small summary of our research findings in the Plantae Research Weekly! ☺️🌱
Plant Science Research Weekly -- Running on empty: How does the absence of mtDNA shape mitochondrial movement and connectivity? (Physiologia Plantarum) @ChusteckiSci.bsky.social (Summary by Irene I. Ikiriko) buff.ly/HOvSCtO
#PlantaePSRW
#PlantaePSRW
Running on empty: How does the absence of mtDNA shape mitochondrial movement and connectivity? | Plantae
Mitochondria move within cells to support bioenergetic function and enable sharing of content, including mitochondrial DNA (mtDNA). Since not all plant mitochondria carry a full set of, or any mtDNA…
buff.ly
September 13, 2025 at 8:34 AM
Nice to see a small summary of our research findings in the Plantae Research Weekly! ☺️🌱
Reposted by Joanna Chustecki
This might be one of the simplest images I captured, but very fascinating nonetheless, as it shows how tight the cytoplasm in a plant cell is. The cytosol and all other organelles are squished between the plasma membrane (magenta) and the central vacuole (its membrane is green)
#MicroscopyMonday
#MicroscopyMonday
September 8, 2025 at 4:22 PM
This might be one of the simplest images I captured, but very fascinating nonetheless, as it shows how tight the cytoplasm in a plant cell is. The cytosol and all other organelles are squished between the plasma membrane (magenta) and the central vacuole (its membrane is green)
#MicroscopyMonday
#MicroscopyMonday
Reposted by Joanna Chustecki
I'm happy to share new work in collaboration with Elena Koslover's lab! First author Keaton developed a mathematical framework for diffusion of soluble material through mitochondrial networks. Then, Lewis lab PhD candidate Camryn used live cell imaging to parameterize... 1/3
August 29, 2025 at 2:33 PM
I'm happy to share new work in collaboration with Elena Koslover's lab! First author Keaton developed a mathematical framework for diffusion of soluble material through mitochondrial networks. Then, Lewis lab PhD candidate Camryn used live cell imaging to parameterize... 1/3
Reposted by Joanna Chustecki
Mitochondrial transfer is a fascinating phenomenon where cells shuttle mitos. The therapeutic potential is compelling and observational science is solid but the mechanism is a black box.
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
August 29, 2025 at 11:01 AM
Mitochondrial transfer is a fascinating phenomenon where cells shuttle mitos. The therapeutic potential is compelling and observational science is solid but the mechanism is a black box.
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
Reposted by Joanna Chustecki
Cytoplasmic inheritance: The transmission of plastid and mitochondrial genomes across cells and generations (Kin Pan Chung) doi.org/10.1093/plph... #PlantScience
July 17, 2025 at 1:05 PM
Cytoplasmic inheritance: The transmission of plastid and mitochondrial genomes across cells and generations (Kin Pan Chung) doi.org/10.1093/plph... #PlantScience
The only meeting I’ve ever been to with a fun fair at night! #brumforever #NGS2025
Thank you to our brilliant delegates, mentors, speakers, the organising committee and our hosts at the University of Birmingham for making New Phytologist next generation scientists 2025 a great success!
August 7, 2025 at 9:36 AM
The only meeting I’ve ever been to with a fun fair at night! #brumforever #NGS2025
It’s been a wonderful meeting so far at #NGS2025 the ECR community is a great place to be right now, and we’ve had some fascinating talks and workshops. Loved presenting my work on mtDNA and mito dynamics #plantscience
August 6, 2025 at 1:42 PM
It’s been a wonderful meeting so far at #NGS2025 the ECR community is a great place to be right now, and we’ve had some fascinating talks and workshops. Loved presenting my work on mtDNA and mito dynamics #plantscience
Reposted by Joanna Chustecki
Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏
www.imperial.ac.uk/media/imperi...
www.imperial.ac.uk/media/imperi...
www.imperial.ac.uk
July 28, 2025 at 4:13 PM
Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏
www.imperial.ac.uk/media/imperi...
www.imperial.ac.uk/media/imperi...
Got papped yesterday at the @biology.ox.ac.uk research showcase spreading the good word about mitochondrial dynamics! So fun being in the new LaMB building and interacting with psych/bio colleagues 🌱🧠
(You can check out the paper I was soapboxing about here: onlinelibrary.wiley.com/doi/10.1111/...)
(You can check out the paper I was soapboxing about here: onlinelibrary.wiley.com/doi/10.1111/...)
July 24, 2025 at 3:46 PM
Got papped yesterday at the @biology.ox.ac.uk research showcase spreading the good word about mitochondrial dynamics! So fun being in the new LaMB building and interacting with psych/bio colleagues 🌱🧠
(You can check out the paper I was soapboxing about here: onlinelibrary.wiley.com/doi/10.1111/...)
(You can check out the paper I was soapboxing about here: onlinelibrary.wiley.com/doi/10.1111/...)
Reposted by Joanna Chustecki
Congrats, Joanna! New article out in collaboration with our Microscopy Core!
An exciting day! Our latest work is now out; we ask the question, are there any differences between plant mitochondria with and without mtDNA? 🌱
onlinelibrary.wiley.com/doi/10.1111/... (1/9)
onlinelibrary.wiley.com/doi/10.1111/... (1/9)
(ID‐ICPMB05) Running on Empty: Mitochondria Without DNA Exhibit Differential Motility and Connectivity
Plant mitochondria are in continuous motion. While providing ATP to other cellular processes, they also constantly consume ATP to move rapidly within the cell. This movement is in part related to tak....
onlinelibrary.wiley.com
July 15, 2025 at 3:34 PM
Congrats, Joanna! New article out in collaboration with our Microscopy Core!
Reposted by Joanna Chustecki
In their Review, Sangheeta Bhattacharjee and Benu Brata Das discuss the roles of topoisomerases in mtDNA maintenance and repair, and highlight their potential as therapeutic targets.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
July 15, 2025 at 7:55 AM
In their Review, Sangheeta Bhattacharjee and Benu Brata Das discuss the roles of topoisomerases in mtDNA maintenance and repair, and highlight their potential as therapeutic targets.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Joanna Chustecki
Proudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells - Nature Metabolism
Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.
www.nature.com
July 14, 2025 at 10:21 AM
Proudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
Reposted by Joanna Chustecki
Thank you to David Macherel, Jose Gualberto and Hakim Mireau for organizing the 2024 ICPMB meeting and the special issue of Phys. Plant. And to Olivier Keech, Allan Rassumsson and Olivier Van Aken for organizing the 2022 ICPMB meeting where I first met Joanna and the seeds of this work germinated.
July 14, 2025 at 8:24 PM
Thank you to David Macherel, Jose Gualberto and Hakim Mireau for organizing the 2024 ICPMB meeting and the special issue of Phys. Plant. And to Olivier Keech, Allan Rassumsson and Olivier Van Aken for organizing the 2022 ICPMB meeting where I first met Joanna and the seeds of this work germinated.
An exciting day! Our latest work is now out; we ask the question, are there any differences between plant mitochondria with and without mtDNA? 🌱
onlinelibrary.wiley.com/doi/10.1111/... (1/9)
onlinelibrary.wiley.com/doi/10.1111/... (1/9)
(ID‐ICPMB05) Running on Empty: Mitochondria Without DNA Exhibit Differential Motility and Connectivity
Plant mitochondria are in continuous motion. While providing ATP to other cellular processes, they also constantly consume ATP to move rapidly within the cell. This movement is in part related to tak....
onlinelibrary.wiley.com
July 14, 2025 at 11:34 AM
An exciting day! Our latest work is now out; we ask the question, are there any differences between plant mitochondria with and without mtDNA? 🌱
onlinelibrary.wiley.com/doi/10.1111/... (1/9)
onlinelibrary.wiley.com/doi/10.1111/... (1/9)
Reposted by Joanna Chustecki
Check out our new preprint in which we use Arabidopsis mutation accumulation lines to quantify just how important the enigmatic plant MSH1 gene is for maintaining low mito and plastid mutation rates. So many mutations detected in msh1 lines!
Feedback appreciated!
www.biorxiv.org/content/10.1...
Feedback appreciated!
www.biorxiv.org/content/10.1...
July 4, 2025 at 3:54 PM
Reposted by Joanna Chustecki
I'm thrilled to share that our story is now out in Science Advances! 🎉 We use quantitative imaging to map the mito central dogma, define translation hubs in the mitochondrial matrix, and show that they're replaced by Mitochondrial Stress Bodies (MSB) when mtRNA processing is perturbed 1/4
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress
Quantitative imaging of the mitochondrial central dogma identifies translation hubs that are suppressed during stress.
www.science.org
April 18, 2025 at 10:56 PM
I'm thrilled to share that our story is now out in Science Advances! 🎉 We use quantitative imaging to map the mito central dogma, define translation hubs in the mitochondrial matrix, and show that they're replaced by Mitochondrial Stress Bodies (MSB) when mtRNA processing is perturbed 1/4
Reposted by Joanna Chustecki
How do cells achieve an optimal mitochondrial distribution? Excited to share a piece of this puzzle: www.science.org/doi/10.1126/...
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution
ARMC1 partitions between distinct outer mitochondrial membrane complexes and the cytosol to control mitochondrial distribution.
www.science.org
April 10, 2025 at 2:49 PM
How do cells achieve an optimal mitochondrial distribution? Excited to share a piece of this puzzle: www.science.org/doi/10.1126/...
Nice to be back in sunny Münster to help out with the GoPMF Imaging Workshop 2025!
April 7, 2025 at 6:35 AM
Nice to be back in sunny Münster to help out with the GoPMF Imaging Workshop 2025!
Reposted by Joanna Chustecki
MITOtalks this week
April 1, 2025 at 4:10 PM
MITOtalks this week
I answered 33 questions for the Women in Research Fellowship Team! It has been a wonderful opportunity, I’d really recommend the #WiRE fellowship to any women ECRs looking at moving to Germany! wire-uni-muenster.de/plant-cells-...
Plant Cells, Big Questions and Bright Minds: A Conversation with Dr Joanna Chustecki - WiRe
In today’s 33-questions-to-episode we are speaking with Dr. Amélia Messara, a chemist and passionate lover of light and alkenes.
wire-uni-muenster.de
February 10, 2025 at 5:09 PM
I answered 33 questions for the Women in Research Fellowship Team! It has been a wonderful opportunity, I’d really recommend the #WiRE fellowship to any women ECRs looking at moving to Germany! wire-uni-muenster.de/plant-cells-...
Here's a little intro I wrote for my time at the University of Münster in the @schwarzlanderlab.bsky.social 🌱
There will be a longer form interview coming soon!🎙️
wire-uni-muenster.de/dr-joanna-ch... (Studying mitos, not birds!) #fellowship #WiRE
There will be a longer form interview coming soon!🎙️
wire-uni-muenster.de/dr-joanna-ch... (Studying mitos, not birds!) #fellowship #WiRE
Dr. Joanna Chustecki: Unravelling the Mysteries of Mitochondrial Motion - WiRe
On this Welcome Wednesday, meet Dr. Samara Danel, a behavioural biologist and cognitive scientist who is researching cognition in birds.
wire-uni-muenster.de
January 16, 2025 at 2:30 PM
Here's a little intro I wrote for my time at the University of Münster in the @schwarzlanderlab.bsky.social 🌱
There will be a longer form interview coming soon!🎙️
wire-uni-muenster.de/dr-joanna-ch... (Studying mitos, not birds!) #fellowship #WiRE
There will be a longer form interview coming soon!🎙️
wire-uni-muenster.de/dr-joanna-ch... (Studying mitos, not birds!) #fellowship #WiRE
Can’t wait to get into these preprints! Incredible insight and experimental/modelling approaches taken
December 23, 2024 at 6:57 PM
Can’t wait to get into these preprints! Incredible insight and experimental/modelling approaches taken