Conor Lee-Smith
@cfleesmith.bsky.social
PhD candidate in the Glick Lab at UChicago
| he/him | Hobbies include watching grass grow, paint dry, and the Golgi mature.
| he/him | Hobbies include watching grass grow, paint dry, and the Golgi mature.
Seems like health care would be a pretty important part of "quality of life" especially for people at retirement age
With its sunny beaches and friendly tax code, Florida is the best state to retire in, according to an annual study. But if you’re looking for a lower cost of living and don’t mind all four seasons, you can find excellent alternatives in these other states. nyti.ms/4hAFsL1
October 30, 2025 at 8:30 PM
Seems like health care would be a pretty important part of "quality of life" especially for people at retirement age
Never a bad time to rewatch this banger from @hbomberguy.bsky.social and get really angry all over again
October 29, 2025 at 7:50 PM
Never a bad time to rewatch this banger from @hbomberguy.bsky.social and get really angry all over again
Seems bad!
Wow. Harvard nuking its PhD programs
- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero
- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero
Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...
www.thecrimson.com
October 21, 2025 at 5:43 PM
Seems bad!
Reposted by Conor Lee-Smith
WHAT WOULD POSSIBLY BE THE MECHANISM THIS IS SUCH CLOWN SHIT
RFK JR: There are many other confirmations -- there are two studies that show children who are circumcised early have double the rate of autism. It’s highly likely because they are given Tylenol
October 9, 2025 at 6:27 PM
WHAT WOULD POSSIBLY BE THE MECHANISM THIS IS SUCH CLOWN SHIT
Updated Zotero without realizing the new version is no longer compatible with ZotFile and now my whole paper organization system is borked and I just don't have the will to deal with that right now
October 9, 2025 at 6:03 PM
Updated Zotero without realizing the new version is no longer compatible with ZotFile and now my whole paper organization system is borked and I just don't have the will to deal with that right now
Reposted by Conor Lee-Smith
I'm a single issue voter now, my issue: revenge
October 1, 2025 at 9:23 PM
I'm a single issue voter now, my issue: revenge
Reposted by Conor Lee-Smith
How do resident Golgi proteins recycle during cisternal maturation? Nice preprint from Adam Krahn in the Glick lab shows different classes of intra-Golgi vesicles in yeast: two COPI-dependent (early and mid) and one late clathrin/AP-1/Ent5 pathway.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 22, 2025 at 6:28 AM
How do resident Golgi proteins recycle during cisternal maturation? Nice preprint from Adam Krahn in the Glick lab shows different classes of intra-Golgi vesicles in yeast: two COPI-dependent (early and mid) and one late clathrin/AP-1/Ent5 pathway.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Conor Lee-Smith
COPI-dependent intra-Golgi recycling at an intermediate stageof cisternal maturation https://www.biorxiv.org/content/10.1101/2025.09.20.677526v1
September 21, 2025 at 10:30 PM
COPI-dependent intra-Golgi recycling at an intermediate stageof cisternal maturation https://www.biorxiv.org/content/10.1101/2025.09.20.677526v1
A little opera in the park/warzone
September 8, 2025 at 12:59 AM
A little opera in the park/warzone
Reposted by Conor Lee-Smith
you'd think the governor of illinois basically going "we're being invaded by an authoritarian" would be something you'd see real easy on the front page of most everything an hour later
September 2, 2025 at 10:02 PM
you'd think the governor of illinois basically going "we're being invaded by an authoritarian" would be something you'd see real easy on the front page of most everything an hour later
Reposted by Conor Lee-Smith
Pritzker: "I refuse to pretend that any of this is normal ... I refuse to fall into the pundit trap that demands we sacrifice vital constitutional rights if it's being done in the fake guise of fighting crime."
September 2, 2025 at 8:20 PM
Pritzker: "I refuse to pretend that any of this is normal ... I refuse to fall into the pundit trap that demands we sacrifice vital constitutional rights if it's being done in the fake guise of fighting crime."
jfc
BREAKING: The Supreme Court lets the Trump administration cut nearly $800 million in health research funding in anti-DEI push.
Supreme Court lets Trump administration cut $783 million of research funding in anti-DEI push
The Supreme Court is allowing the Trump administration to slash hundreds of millions of dollars’ worth of research funding in its push to cut federal diversity, equity and inclusion efforts.
bit.ly
August 21, 2025 at 9:08 PM
jfc
So it's an LLM which has to be trained on the wider internet to be at all useful, which means it has been trained on facts which are at odds with the entire platform of the Republican Party, right?
Trump’s Truth Social launched an AI chatbot, which doesn’t see eye to eye with him.
The Post asked the bot about topics like tariffs, the best president and Jan. 6. Here’s what it said. wapo.st/45vMriv
The Post asked the bot about topics like tariffs, the best president and Jan. 6. Here’s what it said. wapo.st/45vMriv
August 14, 2025 at 7:13 PM
So it's an LLM which has to be trained on the wider internet to be at all useful, which means it has been trained on facts which are at odds with the entire platform of the Republican Party, right?
Just saw a video of someone in a lab somewhere that uses an InstantPot to autoclave their tips and I am shook
July 11, 2025 at 3:53 PM
Just saw a video of someone in a lab somewhere that uses an InstantPot to autoclave their tips and I am shook
Once again, something broke in the building my lab is in and we’ve been asked to evacuate out of an abundance of caution. Good thing they’re putting a BSL3 tuberculosis lab in there!
July 9, 2025 at 9:58 PM
Once again, something broke in the building my lab is in and we’ve been asked to evacuate out of an abundance of caution. Good thing they’re putting a BSL3 tuberculosis lab in there!
Hmm, not the best time to entirely lose power
June 24, 2025 at 2:20 AM
Hmm, not the best time to entirely lose power
Really messed up that I get super productive at like 2am
June 22, 2025 at 7:06 AM
Really messed up that I get super productive at like 2am
Hey @durbin.senate.gov and @duckworth.senate.gov, y'all and your colleagues going to continue to try to work with Republicans like nothing is wrong?
Holy hell. The second half of the video shows FBI agents forcing Senator Padilla to the ground and handcuffing him.
June 12, 2025 at 7:20 PM
Hey @durbin.senate.gov and @duckworth.senate.gov, y'all and your colleagues going to continue to try to work with Republicans like nothing is wrong?
Reposted by Conor Lee-Smith
We need to build some real social stigma around being afraid of cities. You don't have to like them or live there, but a politics built this strongly around watching TV and going "ewww" is embarrassing, and people should be embarrassed by it. It's like "fear of werewolves" being your top issue.
June 10, 2025 at 3:17 PM
We need to build some real social stigma around being afraid of cities. You don't have to like them or live there, but a politics built this strongly around watching TV and going "ewww" is embarrassing, and people should be embarrassed by it. It's like "fear of werewolves" being your top issue.
The woman who works at the Thai place I would go to all the time right next to the apartment I used to live in still recognizes me even though it’s been 2 years since I lived there 🥲
June 7, 2025 at 12:17 AM
The woman who works at the Thai place I would go to all the time right next to the apartment I used to live in still recognizes me even though it’s been 2 years since I lived there 🥲
It’s a little unnerving how quiet the neighborhood feels now that students are largely gone
June 2, 2025 at 11:32 PM
It’s a little unnerving how quiet the neighborhood feels now that students are largely gone
Reposted by Conor Lee-Smith
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
May 23, 2025 at 5:56 PM
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
wake up babe, new yeast just dropped
In the latest #Yeast research article of the series #FantasticYeasts, Pei-Jie Han, Feng-Yan Bai & team describe a new yeast species isolated from a Chinese forest: Saccharomycopsis yichangensis, that can prey on Saccharomyces cerevisiae and other yeasts 😲
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Saccharomycopsis yichangensis sp. nov., a Novel Predacious Yeast Species Isolated From Soil
Saccharomycopsis yichangensis sp. nov. occurs in soil from a subtropical forest in central China. This novel species is homothallic and produces asci containing four spheroidal ascospores, which can ...
onlinelibrary.wiley.com
May 22, 2025 at 9:37 PM
wake up babe, new yeast just dropped