Ashik
@ashikpari.bsky.social
Reposted by Ashik
Just out in @science.org: Together with the lab of @johanneszuber.bsky.social, we used sequential in-vitro/in-vivo screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
October 9, 2025 at 8:12 PM
Just out in @science.org: Together with the lab of @johanneszuber.bsky.social, we used sequential in-vitro/in-vivo screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
Reposted by Ashik
How do #metastases survive (and thrive!) in the #brain microenvironment?
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
September 4, 2025 at 5:41 AM
How do #metastases survive (and thrive!) in the #brain microenvironment?
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
Reposted by Ashik
Congratulations, Michael Dorrity and Anna Erzberger!
The two EMBL Heidelberg group leaders have received ERC Starting Grants that will enable ambitious projects related to developmental timing and tissue self-organisation, respectively.
Learn more: www.embl.org/news/awards-...
The two EMBL Heidelberg group leaders have received ERC Starting Grants that will enable ambitious projects related to developmental timing and tissue self-organisation, respectively.
Learn more: www.embl.org/news/awards-...
September 4, 2025 at 10:09 AM
Congratulations, Michael Dorrity and Anna Erzberger!
The two EMBL Heidelberg group leaders have received ERC Starting Grants that will enable ambitious projects related to developmental timing and tissue self-organisation, respectively.
Learn more: www.embl.org/news/awards-...
The two EMBL Heidelberg group leaders have received ERC Starting Grants that will enable ambitious projects related to developmental timing and tissue self-organisation, respectively.
Learn more: www.embl.org/news/awards-...
Reposted by Ashik
Three new @erc.europa.eu Starting Grants for vascular researchers: Congratulations to Vanessa Coelho-Santos (@vcoelhosantoslab.bsky.social) for "AngioArchitects“ (LS5], Leire Bejarano for "MetaVasc" (LS4], and Mahak Singhal for "Vascular Rhythm" (LS4). Great success!
September 4, 2025 at 10:47 AM
Three new @erc.europa.eu Starting Grants for vascular researchers: Congratulations to Vanessa Coelho-Santos (@vcoelhosantoslab.bsky.social) for "AngioArchitects“ (LS5], Leire Bejarano for "MetaVasc" (LS4], and Mahak Singhal for "Vascular Rhythm" (LS4). Great success!
Reposted by Ashik
Congratulations to Mahak Singhal @uniheidelberg.bsky.social on being awarded an @erc.europa.eu Starting Grant for his project "Vascular-Rhythm" focussing on "DeClocking the vascular rhythmic control of tissue homeostasis and disease initiation". Pioneering a new branch of vascular research!
September 4, 2025 at 10:14 AM
Congratulations to Mahak Singhal @uniheidelberg.bsky.social on being awarded an @erc.europa.eu Starting Grant for his project "Vascular-Rhythm" focussing on "DeClocking the vascular rhythmic control of tissue homeostasis and disease initiation". Pioneering a new branch of vascular research!
Reposted by Ashik
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
July 17, 2025 at 11:28 AM
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ashik
Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...
July 14, 2025 at 10:09 AM
Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...
Reposted by Ashik
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
June 26, 2025 at 8:15 AM
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
Reposted by Ashik
Angiocrine signaling is rocking - pericrine signaling is the new kid on the block: Hepatic stellate cells control liver function (‘HSCs make the liver great again’) - now published @nature.com (www.nature.com/articles/s41586-025-08677-w). Fantastic collaboration with the Schwabe lab at Columbia Uni
March 12, 2025 at 4:33 PM
Angiocrine signaling is rocking - pericrine signaling is the new kid on the block: Hepatic stellate cells control liver function (‘HSCs make the liver great again’) - now published @nature.com (www.nature.com/articles/s41586-025-08677-w). Fantastic collaboration with the Schwabe lab at Columbia Uni
Reposted by Ashik
Very happy to see this out!
Amazing work by Roberto Würth and team at @hi-stem and @dkfz.bsky.social
Congrats! 🎉🎉
Amazing work by Roberto Würth and team at @hi-stem and @dkfz.bsky.social
Congrats! 🎉🎉
Now online - Article
"Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling"
✏️by Roberto Würth & Andreas Trumpp and team
🔗https://www.nature.com/articles/s43018-024-00882-2?utm_source=bluesky&utm_medium=social&utm_campaign=natcancer
"Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling"
✏️by Roberto Würth & Andreas Trumpp and team
🔗https://www.nature.com/articles/s43018-024-00882-2?utm_source=bluesky&utm_medium=social&utm_campaign=natcancer
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling - Nature Cancer
Trumpp and colleagues develop a method to obtain long-term circulating tumor cell-derived organoids from individuals with metastatic breast cancer and identify the neuregulin 1–HER3 axis as important ...
www.nature.com
February 26, 2025 at 10:23 PM
Very happy to see this out!
Amazing work by Roberto Würth and team at @hi-stem and @dkfz.bsky.social
Congrats! 🎉🎉
Amazing work by Roberto Würth and team at @hi-stem and @dkfz.bsky.social
Congrats! 🎉🎉
Reposted by Ashik
We are excited to share our work on Context-dependent response of endothelial cells to PIK3CA mutation. A tour the force of many; thank you all for your invaluable contribution. @aangulou.bsky.social @ruibenedito.bsky.social @debocklab.bsky.social @sandradcastillo.bsky.social
bit.ly/4blKSqa
bit.ly/4blKSqa
Context-dependent response of endothelial cells to PIK3CA mutation
Cancer mutations in the PIK3CA gene cause congenital disorders. The endothelium is among the most frequently affected tissues in these disorders, displaying aberrant vascular overgrowth in the form of...
bit.ly
February 26, 2025 at 12:19 PM
We are excited to share our work on Context-dependent response of endothelial cells to PIK3CA mutation. A tour the force of many; thank you all for your invaluable contribution. @aangulou.bsky.social @ruibenedito.bsky.social @debocklab.bsky.social @sandradcastillo.bsky.social
bit.ly/4blKSqa
bit.ly/4blKSqa
Reposted by Ashik
Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature.
We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social
www.nature.com/articles/s41...
We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social
www.nature.com/articles/s41...
February 18, 2025 at 9:37 AM
Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature.
We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social
www.nature.com/articles/s41...
We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social
www.nature.com/articles/s41...
Reposted by Ashik
#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. www.nature.com/articles/s41... #CancerBiology
February 13, 2025 at 12:16 PM
#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. www.nature.com/articles/s41... #CancerBiology
Reposted by Ashik
We have a feeling you'll be interested in this one.
Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪
Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪
Has Bluesky replaced X for scientists? Take Nature’s poll
The research community has flocked to the social-media platform Bluesky. Tell us about your experience.
go.nature.com
January 14, 2025 at 11:39 PM
We have a feeling you'll be interested in this one.
Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪
Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪
Reposted by Ashik
Epigenetic regulation of placental vascularization - now published in Developmental Cell (www.sciencedirect.com/science/arti...). Congratulations & thanks to Stephanie Gehrs for fantastic work and paving the way of the www.augustinlab.de into the world of vascular epigenetics. There’s more to come!
January 14, 2025 at 7:52 PM
Epigenetic regulation of placental vascularization - now published in Developmental Cell (www.sciencedirect.com/science/arti...). Congratulations & thanks to Stephanie Gehrs for fantastic work and paving the way of the www.augustinlab.de into the world of vascular epigenetics. There’s more to come!