Reposted by Toth B.
Reposted by Toth B.
Reposted by Toth B.
Branching out of the cytoskeleton: ER staining is tricky but when it works it's 🔥. COS cell labeled for mitochondria (blue), ER (yellow) and actin (gray) 🧪
January 30, 2025 at 8:50 PM
Branching out of the cytoskeleton: ER staining is tricky but when it works it's 🔥. COS cell labeled for mitochondria (blue), ER (yellow) and actin (gray) 🧪
Reposted by Toth B.
High-throughput expansion microscopy takes shape.
https://elifesciences.org/articles/96025?utm_source=bluesky&utm_medium=social&utm_campaign=organic
https://elifesciences.org/articles/96025?utm_source=bluesky&utm_medium=social&utm_campaign=organic
January 22, 2025 at 9:01 PM
High-throughput expansion microscopy takes shape.
https://elifesciences.org/articles/96025?utm_source=bluesky&utm_medium=social&utm_campaign=organic
https://elifesciences.org/articles/96025?utm_source=bluesky&utm_medium=social&utm_campaign=organic
Reposted by Toth B.
Receiving one or two doses of HPV vaccines prior to age 17, especially for those initiating before age 15, has comparable effectiveness against high-grade cervical lesions with those who received three doses. #Lancet
Open Access
www.science.org/doi/10.1126/...
Open Access
www.science.org/doi/10.1126/...
Sexually dimorphic dopaminergic circuits determine sex preference
Sociosexual preference is critical for reproduction and survival. However, neural mechanisms encoding social decisions on sex preference remain unclear. In this study, we show that both male and femal...
www.science.org
January 10, 2025 at 4:02 AM
Receiving one or two doses of HPV vaccines prior to age 17, especially for those initiating before age 15, has comparable effectiveness against high-grade cervical lesions with those who received three doses. #Lancet
Open Access
www.science.org/doi/10.1126/...
Open Access
www.science.org/doi/10.1126/...
Reposted by Toth B.
📢Vote for the 2024 Development cover image of the year
@dev-journal.bsky.social featured 24 cover images in 2024. Now is the chance to pick your favourite!
Browse through the images and vote by 13 Jan:
https://thenode.biologists.com/vote-for-the-2024-development-cover-image-of-the-year/
#DevBio
@dev-journal.bsky.social featured 24 cover images in 2024. Now is the chance to pick your favourite!
Browse through the images and vote by 13 Jan:
https://thenode.biologists.com/vote-for-the-2024-development-cover-image-of-the-year/
#DevBio
December 27, 2024 at 1:56 PM
📢Vote for the 2024 Development cover image of the year
@dev-journal.bsky.social featured 24 cover images in 2024. Now is the chance to pick your favourite!
Browse through the images and vote by 13 Jan:
https://thenode.biologists.com/vote-for-the-2024-development-cover-image-of-the-year/
#DevBio
@dev-journal.bsky.social featured 24 cover images in 2024. Now is the chance to pick your favourite!
Browse through the images and vote by 13 Jan:
https://thenode.biologists.com/vote-for-the-2024-development-cover-image-of-the-year/
#DevBio
Reposted by Toth B.
Transcription
Credit: SmartBiology
Credit: SmartBiology
January 6, 2025 at 1:41 AM
Transcription
Credit: SmartBiology
Credit: SmartBiology
Reposted by Toth B.
January 6, 2025 at 3:40 AM
Reposted by Toth B.
Electric fence or radial glia? These cells🟡 are present only during 🧠development in the neocortex and guide immature neurons 🟣to their final position! Microglia/macrophages in 🔵. It was supposed to be a #FluorescenceFriday, now a #SynapticSunday, maybe #MicroscopyMonday, depending where you are! 🤓
January 6, 2025 at 3:24 AM
Electric fence or radial glia? These cells🟡 are present only during 🧠development in the neocortex and guide immature neurons 🟣to their final position! Microglia/macrophages in 🔵. It was supposed to be a #FluorescenceFriday, now a #SynapticSunday, maybe #MicroscopyMonday, depending where you are! 🤓
Reposted by Toth B.
Remember my programmer friends, that your work has value.
Remember to write programs now and then, not for your boss, or your company, but solely for your own benefit.
You have the ability to craft faithful servants that will perform useful tasks until their silicon brains literally fall apart.
Remember to write programs now and then, not for your boss, or your company, but solely for your own benefit.
You have the ability to craft faithful servants that will perform useful tasks until their silicon brains literally fall apart.
December 28, 2024 at 4:21 AM
Remember my programmer friends, that your work has value.
Remember to write programs now and then, not for your boss, or your company, but solely for your own benefit.
You have the ability to craft faithful servants that will perform useful tasks until their silicon brains literally fall apart.
Remember to write programs now and then, not for your boss, or your company, but solely for your own benefit.
You have the ability to craft faithful servants that will perform useful tasks until their silicon brains literally fall apart.
Reposted by Toth B.
A favorite commission this year, a dividing cell with an extra detail. Colleagues of a retiring researcher commissioned me to add the specific structure she worked on—the spindle pole body—to the sculpture. Here it is close up, in sterling silver embedded in the bronze nuclear membrane. 🔬#SciArt
December 28, 2024 at 2:05 AM
A favorite commission this year, a dividing cell with an extra detail. Colleagues of a retiring researcher commissioned me to add the specific structure she worked on—the spindle pole body—to the sculpture. Here it is close up, in sterling silver embedded in the bronze nuclear membrane. 🔬#SciArt
Reposted by Toth B.
Breathing polluted air increases the risk of osteoporosis. #Science
Open Access
www.science.org/doi/epdf/10....
Open Access
www.science.org/doi/epdf/10....
December 28, 2024 at 2:48 AM
Breathing polluted air increases the risk of osteoporosis. #Science
Open Access
www.science.org/doi/epdf/10....
Open Access
www.science.org/doi/epdf/10....
Rube Goldberg machine pill
December 26, 2024 at 2:04 AM
Rube Goldberg machine pill
Reposted by Toth B.
Gene editing tool reduces Alzheimer’s plaque precursor
"The application in live mice shows the improved efficiency of the tool, called SPLICER, over the current standard in gene editing technology, as well as the potential for application in other diseases."
www.nature.com/articles/s41...
"The application in live mice shows the improved efficiency of the tool, called SPLICER, over the current standard in gene editing technology, as well as the potential for application in other diseases."
www.nature.com/articles/s41...
SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping - Nature Communications
Exon skipping technologies remain hindered by aberrant splicing and low efficacy. Here, Miskalis et.al. developed SPLICER, a Cas9 base editor toolbox which enhances overall exon skipping efficiency an...
idp.nature.com
December 24, 2024 at 1:04 AM
Gene editing tool reduces Alzheimer’s plaque precursor
"The application in live mice shows the improved efficiency of the tool, called SPLICER, over the current standard in gene editing technology, as well as the potential for application in other diseases."
www.nature.com/articles/s41...
"The application in live mice shows the improved efficiency of the tool, called SPLICER, over the current standard in gene editing technology, as well as the potential for application in other diseases."
www.nature.com/articles/s41...
Reposted by Toth B.
TLDR: Academics from low-income backgrounds are more like to push the needle on science, but less likely to receive credit for doing so. 🥴
#econsky #academicsky
#econsky #academicsky
Academics from poorer socio-economic backgrounds are more likely to
- not publish
- have outstanding publication records
- introduce more novel scientific concepts
- less likely to receive recognition, as measured by citations, Nobel Prize nominations, and awards.
www.nber.org/papers/w33289
- not publish
- have outstanding publication records
- introduce more novel scientific concepts
- less likely to receive recognition, as measured by citations, Nobel Prize nominations, and awards.
www.nber.org/papers/w33289
December 23, 2024 at 12:31 PM
TLDR: Academics from low-income backgrounds are more like to push the needle on science, but less likely to receive credit for doing so. 🥴
#econsky #academicsky
#econsky #academicsky
Reposted by Toth B.
This morning, I saw #AChristmasCarolVR, which was a live production of the Dickens classic in VR! Social VR experiences (for me) have the excitement of computer games in the 1980s: the technology is accessible enough to reach a wide audience, and the limitations are a driver for a ton of innovation
December 22, 2024 at 6:02 AM
This morning, I saw #AChristmasCarolVR, which was a live production of the Dickens classic in VR! Social VR experiences (for me) have the excitement of computer games in the 1980s: the technology is accessible enough to reach a wide audience, and the limitations are a driver for a ton of innovation
Reposted by Toth B.
Microplastics (driving is the major source) in the air may be leading to cancers and infertility.
Open access
pubs.acs.org/doi/10.1021/...
Open access
pubs.acs.org/doi/10.1021/...
December 22, 2024 at 4:47 AM
Microplastics (driving is the major source) in the air may be leading to cancers and infertility.
Open access
pubs.acs.org/doi/10.1021/...
Open access
pubs.acs.org/doi/10.1021/...
Reposted by Toth B.
For #FluorescenceFriday, tau (cyan) is shown along with microtubules in primary hippocampal neurons 🔬 #neuroscience #microscopy
December 20, 2024 at 4:40 PM
For #FluorescenceFriday, tau (cyan) is shown along with microtubules in primary hippocampal neurons 🔬 #neuroscience #microscopy
Reposted by Toth B.
🔬My first try on #FluorescenceFriday
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
December 20, 2024 at 7:08 PM
🔬My first try on #FluorescenceFriday
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
Reposted by Toth B.
Wonderful new work by @drewberry.bsky.social Beautifully animated and wonderful sound design #sciart
Delighted to publish my new molecular animation:
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tv
YouTube video by WEHImovies
youtu.be
December 5, 2024 at 6:40 AM
Wonderful new work by @drewberry.bsky.social Beautifully animated and wonderful sound design #sciart
Reposted by Toth B.
Delighted to publish my new molecular animation:
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tv
YouTube video by WEHImovies
youtu.be
December 4, 2024 at 12:07 AM
Delighted to publish my new molecular animation:
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
Reposted by Toth B.
If you're at #ASCB2024 and want to learn more about my research on learning in single cells, please come to my talk "Probing the molecular substrates of memory in the single cell Stentor coeruleus" at 5:35 pm today!
How can a single cell learn without a brain or nervous system? We explore this in our new preprint with
@wallaceucsf.bsky.social! We discovered that central features of learning in single cells can be accounted for by a model based on receptor inactivation bit.ly/3CDukfS 🧵 1/n
@wallaceucsf.bsky.social! We discovered that central features of learning in single cells can be accounted for by a model based on receptor inactivation bit.ly/3CDukfS 🧵 1/n
December 17, 2024 at 6:15 PM
If you're at #ASCB2024 and want to learn more about my research on learning in single cells, please come to my talk "Probing the molecular substrates of memory in the single cell Stentor coeruleus" at 5:35 pm today!
Reposted by Toth B.
A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far.
Learn more: scim.ag/4gEQU6n
Learn more: scim.ag/4gEQU6n
This odd fish has 30 times as much DNA as humans—a new record for animals
Lacking key genes that control selfish bits of DNA, the South American lungfish’s genome just grew and grew
scim.ag
December 16, 2024 at 2:16 PM
A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far.
Learn more: scim.ag/4gEQU6n
Learn more: scim.ag/4gEQU6n
Reposted by Toth B.
Setting up conference posters can be quite painful
December 16, 2024 at 1:46 AM
Setting up conference posters can be quite painful