Angélica Díaz Basabe
@angiedb.bsky.social
Postdoctoral Researcher at Karolinska Institutet. Love microbes and mucosal immunity, but I can also (re)post about anything I find interesting 🙂
Reposted by Angélica Díaz Basabe
Slo-mo
'All three awards (...) honored achievements rooted in fundamental research from decades ago. Some experts interpret the selections by the Royal Swedish Academy of Sciences as representing the importance of slow, basic science, work pursued out of a desire to better understand the world.'
Nobel Prizes This Year Offer Three Cheers for Slow Science
www.nytimes.com
October 10, 2025 at 6:18 PM
Slo-mo
Reposted by Angélica Díaz Basabe
This is how we experience the Nobel Prize announcement every year, with excitement!
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
October 6, 2025 at 3:56 PM
This is how we experience the Nobel Prize announcement every year, with excitement!
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
Reposted by Angélica Díaz Basabe
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
October 6, 2025 at 9:42 AM
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
Reposted by Angélica Díaz Basabe
I want to start a new global movement:
Meetless Monday - we encourages people to reduce their meeting activity by one day each week for personal health and the planet's well-being.
Meetless Monday - we encourages people to reduce their meeting activity by one day each week for personal health and the planet's well-being.
September 10, 2025 at 6:09 AM
I want to start a new global movement:
Meetless Monday - we encourages people to reduce their meeting activity by one day each week for personal health and the planet's well-being.
Meetless Monday - we encourages people to reduce their meeting activity by one day each week for personal health and the planet's well-being.
Reposted by Angélica Díaz Basabe
By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers in Science have enabled ear tissue regeneration in mice.
Learn more: scim.ag/3TzUSnH
Learn more: scim.ag/3TzUSnH
Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch
Mammals display prominent diversity in the ability to regenerate damaged ear pinna, but the genetic changes underlying the failure of regeneration remain elusive. We performed comparative single-cell ...
scim.ag
June 27, 2025 at 7:49 PM
By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers in Science have enabled ear tissue regeneration in mice.
Learn more: scim.ag/3TzUSnH
Learn more: scim.ag/3TzUSnH
Reposted by Angélica Díaz Basabe
Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis @natimmunol.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
June 27, 2025 at 6:20 PM
Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis @natimmunol.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Angélica Díaz Basabe
Podcast and Text: The Tölzer Knabenchor will premiere Bach cantatas with original 1730s vocal forces. Managing director Barbara Schmidt-Gaden urges stronger music education in Bavarian schools, citing declining choir interest. backstageclassical.com/mehr-musik-i...
»Mehr Musik in die Schule!« - BackstageClassical
Der Tölzer Knabenchor wird erstmals Bach-Kantaten in der original Stimmstärke aufführen. Geschäftsführerin Barbara Schmidt-Gaden fordert von Bayerns Politik mehr Bewusstsein für Musik in den Schulen.
backstageclassical.com
June 11, 2025 at 8:47 PM
Podcast and Text: The Tölzer Knabenchor will premiere Bach cantatas with original 1730s vocal forces. Managing director Barbara Schmidt-Gaden urges stronger music education in Bavarian schools, citing declining choir interest. backstageclassical.com/mehr-musik-i...
Reposted by Angélica Díaz Basabe
Joulia et al use single cell spatial transcriptomics to profile the lung in health and during asthma and identify discrete proinflammatory spatial niches that produce alarmins and chemokines. Read it here: rdcu.be/epjN7
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma
Nature Immunology - Here, the authors use single-cell spatial transcriptomics to profile the airway wall landscape in health and during asthma. Discrete proinflammatory ecosystems containing...
rdcu.be
June 3, 2025 at 8:56 PM
Joulia et al use single cell spatial transcriptomics to profile the lung in health and during asthma and identify discrete proinflammatory spatial niches that produce alarmins and chemokines. Read it here: rdcu.be/epjN7
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Angélica Díaz Basabe
Out now in #Science #Immunology:
Christopher Hall & colleagues at @aucklanduni.bsky.social report in #zebrafish that the #circadian clock gene per2 boosts daytime #antibacterial activity in #neutrophils by promoting infection-responsive hmgb1a expression!
Christopher Hall & colleagues at @aucklanduni.bsky.social report in #zebrafish that the #circadian clock gene per2 boosts daytime #antibacterial activity in #neutrophils by promoting infection-responsive hmgb1a expression!
A light-regulated circadian timer optimizes neutrophil bactericidal activity to boost daytime immunity
The neutrophil clockwork boosts daytime immunity against bacterial infection.
www.science.org
May 23, 2025 at 7:10 PM
Out now in #Science #Immunology:
Christopher Hall & colleagues at @aucklanduni.bsky.social report in #zebrafish that the #circadian clock gene per2 boosts daytime #antibacterial activity in #neutrophils by promoting infection-responsive hmgb1a expression!
Christopher Hall & colleagues at @aucklanduni.bsky.social report in #zebrafish that the #circadian clock gene per2 boosts daytime #antibacterial activity in #neutrophils by promoting infection-responsive hmgb1a expression!
Reposted by Angélica Díaz Basabe
#ZebrafishFunFacts While casper zebrafish 👻 are transparent, they are not considered ‘albino’ as they have pigmented eyes. To make a true albino, you have to cross casper w/ the albino allele (slc45a2), which makes a ‘crystal’ mutant. To learn more about crystal, see www.nature.com/articles/sre... 🧪
May 24, 2025 at 8:06 AM
#ZebrafishFunFacts While casper zebrafish 👻 are transparent, they are not considered ‘albino’ as they have pigmented eyes. To make a true albino, you have to cross casper w/ the albino allele (slc45a2), which makes a ‘crystal’ mutant. To learn more about crystal, see www.nature.com/articles/sre... 🧪
Reposted by Angélica Díaz Basabe
Microbiota colonising the new born colon prime goblet cells producing the gut-protective mucus
📷 Åsa Johansson et al @gobletcellguy.bsky.social
University of Gothenburg in @jem.org
➡️ bpod.org.uk/archive/2025...
📷 Åsa Johansson et al @gobletcellguy.bsky.social
University of Gothenburg in @jem.org
➡️ bpod.org.uk/archive/2025...
May 15, 2025 at 10:20 AM
Microbiota colonising the new born colon prime goblet cells producing the gut-protective mucus
📷 Åsa Johansson et al @gobletcellguy.bsky.social
University of Gothenburg in @jem.org
➡️ bpod.org.uk/archive/2025...
📷 Åsa Johansson et al @gobletcellguy.bsky.social
University of Gothenburg in @jem.org
➡️ bpod.org.uk/archive/2025...
Reposted by Angélica Díaz Basabe
I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing
Promoting intestinal regeneration and enhancing mucosal healing have emerged as promising therapeutic alternatives for treating intestinal disorders t…
www.sciencedirect.com
May 14, 2025 at 9:35 AM
I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
Reposted by Angélica Díaz Basabe
Postdoctoral position in Computational Biology open !
Our Lab is trying to understand the molecular and cellular mechanisms involved in establishing intestinal immune homeostasis and how a breakdown of these mechanisms may lead to diseases
More info 👇 :
lnkd.in/dQZq55nv
lnkd.in/d6sbw59P
Our Lab is trying to understand the molecular and cellular mechanisms involved in establishing intestinal immune homeostasis and how a breakdown of these mechanisms may lead to diseases
More info 👇 :
lnkd.in/dQZq55nv
lnkd.in/d6sbw59P
May 9, 2025 at 8:00 AM
Postdoctoral position in Computational Biology open !
Our Lab is trying to understand the molecular and cellular mechanisms involved in establishing intestinal immune homeostasis and how a breakdown of these mechanisms may lead to diseases
More info 👇 :
lnkd.in/dQZq55nv
lnkd.in/d6sbw59P
Our Lab is trying to understand the molecular and cellular mechanisms involved in establishing intestinal immune homeostasis and how a breakdown of these mechanisms may lead to diseases
More info 👇 :
lnkd.in/dQZq55nv
lnkd.in/d6sbw59P
Reposted by Angélica Díaz Basabe
Review @naturerevdrugdisc.bsky.social @quintanalab.bsky.social
The aryl hydrocarbon receptor: a rehabilitated target for therapeutic immune modulation
www.nature.com/articles/s41...
The aryl hydrocarbon receptor: a rehabilitated target for therapeutic immune modulation
www.nature.com/articles/s41...
April 17, 2025 at 5:38 PM
Review @naturerevdrugdisc.bsky.social @quintanalab.bsky.social
The aryl hydrocarbon receptor: a rehabilitated target for therapeutic immune modulation
www.nature.com/articles/s41...
The aryl hydrocarbon receptor: a rehabilitated target for therapeutic immune modulation
www.nature.com/articles/s41...
Reposted by Angélica Díaz Basabe
we had a magnitude 5.2 earthquake this morning that struck our microbiology research lab (and greater san diego county) — everyone got to experience a little brownian motion but fortunately no major damage
April 14, 2025 at 7:56 PM
we had a magnitude 5.2 earthquake this morning that struck our microbiology research lab (and greater san diego county) — everyone got to experience a little brownian motion but fortunately no major damage
Reposted by Angélica Díaz Basabe
Review @naturemedicine.bsky.social @gilbertjacka.bsky.social
Clinical translation of microbiome research
www.nature.com/articles/s41...
Clinical translation of microbiome research
www.nature.com/articles/s41...
April 12, 2025 at 4:30 PM
Review @naturemedicine.bsky.social @gilbertjacka.bsky.social
Clinical translation of microbiome research
www.nature.com/articles/s41...
Clinical translation of microbiome research
www.nature.com/articles/s41...
Reposted by Angélica Díaz Basabe
Inflammatory cytokines hijack a brain circuit to cause apathy in cancer @science.org @kepecslab.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
April 10, 2025 at 7:21 PM
Inflammatory cytokines hijack a brain circuit to cause apathy in cancer @science.org @kepecslab.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Angélica Díaz Basabe
Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
March 28, 2025 at 7:31 PM
Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Angélica Díaz Basabe
The astronautes that returned from space after 9 months couldn't recognize the world they returned to and the progress that has been made:
"So many cells have been sequenced!"
"So many cells have been sequenced!"
March 19, 2025 at 4:41 AM
The astronautes that returned from space after 9 months couldn't recognize the world they returned to and the progress that has been made:
"So many cells have been sequenced!"
"So many cells have been sequenced!"
Reposted by Angélica Díaz Basabe
At @standupforscience.bsky.social and the signs are statistically significantly excellent
March 7, 2025 at 6:51 PM
At @standupforscience.bsky.social and the signs are statistically significantly excellent
Reposted by Angélica Díaz Basabe
Honored that the latest issue of @mucosalimmunol.bsky.social features ‘The Prisoner’s Dilemma’ for mucosal immunology on its cover!
A big thank you to @gamonasterioo.bsky.social for the incredible artwork.
Read my latest perspective here 👇
www.mucosalimmunology.org/article/S193...
A big thank you to @gamonasterioo.bsky.social for the incredible artwork.
Read my latest perspective here 👇
www.mucosalimmunology.org/article/S193...
February 21, 2025 at 2:57 PM
Honored that the latest issue of @mucosalimmunol.bsky.social features ‘The Prisoner’s Dilemma’ for mucosal immunology on its cover!
A big thank you to @gamonasterioo.bsky.social for the incredible artwork.
Read my latest perspective here 👇
www.mucosalimmunology.org/article/S193...
A big thank you to @gamonasterioo.bsky.social for the incredible artwork.
Read my latest perspective here 👇
www.mucosalimmunology.org/article/S193...
Reposted by Angélica Díaz Basabe
To visualize niches, a ‘Swiss roll’ section of the small intestine was stained for CODEX multiplexed imaging. This method, in conjunction with the tissue-rolling technique, allows the gut architecture to be dissected at single-cell resolution.
Check the paper out👇🏼
doi.org/10.1038/s415...
Check the paper out👇🏼
doi.org/10.1038/s415...
February 8, 2025 at 9:37 AM
To visualize niches, a ‘Swiss roll’ section of the small intestine was stained for CODEX multiplexed imaging. This method, in conjunction with the tissue-rolling technique, allows the gut architecture to be dissected at single-cell resolution.
Check the paper out👇🏼
doi.org/10.1038/s415...
Check the paper out👇🏼
doi.org/10.1038/s415...
Reposted by Angélica Díaz Basabe
Serotonin attenuates TNF-induced intestinal inflammation by interacting with human mucosal tissue
www.nature.com/articles/s12...
www.nature.com/articles/s12...
February 3, 2025 at 5:46 PM
Serotonin attenuates TNF-induced intestinal inflammation by interacting with human mucosal tissue
www.nature.com/articles/s12...
www.nature.com/articles/s12...
Reposted by Angélica Díaz Basabe
B cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
February 2, 2025 at 5:18 PM
B cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...