Eduardo Villablanca
@ejvillablanca.bsky.social
Mucosal Immunologist interested in the complexity of IBD. Professor @Karolinskainst, Wallenberg Fellow & editor @MucosalImmunol. Opinions are my own
Pinned
Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is a manifestation of an inappropriate inflammatory response to intestinal microorganisms in genetically s...
ki.se
Welcome to our new KI lab webpage!
Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca
ki.se/en/research/...
Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca
ki.se/en/research/...
🥷“Lab manager in immunology and spatial biology”
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
Lab manager inom immunologi och spatiell biolog | Eduardo Villablanca
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
“Lab manager in immunology and spatial biology”
Come join the Engblom and Villablanca labs! A lab manager position is avail...
www.linkedin.com
November 20, 2025 at 4:29 PM
🥷“Lab manager in immunology and spatial biology”
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
42 ectopic oral species found in the gut could be predictive of systemic diseases 😲
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Oral microbiome shows rising importance in human health. Cha et al. present the human
reference oral microbiome (HROM), comprising 72,641 high-quality genomes from 3,426
species, including 2,019 previ...
www.cell.com
November 19, 2025 at 8:49 PM
42 ectopic oral species found in the gut could be predictive of systemic diseases 😲
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
“Women who consumed the highest amounts of ultraprocessed foods — 10 servings per day on average — had a 45 percent higher risk of developing conventional adenomas, compared with those who consumed the lowest amounts”
www.linkedin.com/posts/harvar...
www.linkedin.com/posts/harvar...
Researchers link ultraprocessed foods to precancerous polyps — Harvard Gazette | Harvard University
Colorectal cancer diagnoses have become increasingly common in adults 50 or younger in recent years, particularly in high-income countries like the U.S. A new study led by Harvard and Mass General Bri...
www.linkedin.com
November 18, 2025 at 6:56 AM
“Women who consumed the highest amounts of ultraprocessed foods — 10 servings per day on average — had a 45 percent higher risk of developing conventional adenomas, compared with those who consumed the lowest amounts”
www.linkedin.com/posts/harvar...
www.linkedin.com/posts/harvar...
Karolinska Institutet is recruiting three Assistant Professors through the @SciLifeLab and @DDLS programs!
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
Call for SciLifeLab and DDLS Fellows 2025
Karolinska Institutet is recruiting three Assistant Professors in two programs tied to SciLifeLab. SciLifeLab and DDLS Fellows (Assistant Professors) are six-year positions with generous recruitment p...
news.ki.se
October 28, 2025 at 5:34 PM
Karolinska Institutet is recruiting three Assistant Professors through the @SciLifeLab and @DDLS programs!
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
Packed room for @reinacampos.bsky.social’s talk at @cmm @ki.se!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
October 28, 2025 at 11:21 AM
Packed room for @reinacampos.bsky.social’s talk at @cmm @ki.se!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
Using Zebrafish to study CD8 T cells and tumors interactions in vivi the Zon lab identified “CRATER tumor niches”.
CRATER facilitate CD8+ T cell engagement and correspond with immunotherapy success
Cell www.cell.com/cell/fulltex...
CRATER facilitate CD8+ T cell engagement and correspond with immunotherapy success
Cell www.cell.com/cell/fulltex...
CRATER tumor niches facilitate CD8+ T cell engagement and correspond with immunotherapy success
CD8+ T cells preferentially engage tumor cells in pockets termed CRATERs, which are
rich with antigen presentation molecules and breach into the tumor mass from the stromal
compartment. CRATERs expand...
www.cell.com
October 26, 2025 at 7:08 AM
Using Zebrafish to study CD8 T cells and tumors interactions in vivi the Zon lab identified “CRATER tumor niches”.
CRATER facilitate CD8+ T cell engagement and correspond with immunotherapy success
Cell www.cell.com/cell/fulltex...
CRATER facilitate CD8+ T cell engagement and correspond with immunotherapy success
Cell www.cell.com/cell/fulltex...
Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance
Cell www.cell.com/cell/fulltex...
Cell www.cell.com/cell/fulltex...
Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance
Cancer cells exploit distant tissues and organs to escape immune surveillance by activating
nociceptive neurons, which remodel tumor-draining lymph nodes into an immune-suppressed
state. Blocking this...
www.cell.com
October 26, 2025 at 6:58 AM
Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance
Cell www.cell.com/cell/fulltex...
Cell www.cell.com/cell/fulltex...
Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest: Cancer Cell www.cell.com/cancer-cell/...
Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest
Galeano Niño et al. show that extracellular bacteria dominate colorectal and oral
tumor microniches, remodeling the microenvironment with reduced cell density, scattered
epithelium, and low proliferat...
www.cell.com
October 20, 2025 at 6:54 PM
Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest: Cancer Cell www.cell.com/cancer-cell/...
Reposted by Eduardo Villablanca
Great reference to get up to speed on B cells in IBD from our good friend @ejvillablanca.bsky.social
TL;DR B cells aren’t just bystanders in IBD, they’re active players in both gut protection, pathology and mucosal healing.
doi.org/10.1016/j.im... 🧪
TL;DR B cells aren’t just bystanders in IBD, they’re active players in both gut protection, pathology and mucosal healing.
doi.org/10.1016/j.im... 🧪
B cells in inflammatory bowel disease
Inflammatory bowel diseases (IBD) have traditionally been considered T cell-driven disorders; however, accumulating evidence challenges this view and …
doi.org
October 10, 2025 at 7:22 AM
Great reference to get up to speed on B cells in IBD from our good friend @ejvillablanca.bsky.social
TL;DR B cells aren’t just bystanders in IBD, they’re active players in both gut protection, pathology and mucosal healing.
doi.org/10.1016/j.im... 🧪
TL;DR B cells aren’t just bystanders in IBD, they’re active players in both gut protection, pathology and mucosal healing.
doi.org/10.1016/j.im... 🧪
Yesterday marked my installation as Professor at Karolinska Institutet
I’m extremely grateful to my family, friends, and lab members who joined to celebrate this milestone.
Excited for the journey ahead!
@ki.se
I’m extremely grateful to my family, friends, and lab members who joined to celebrate this milestone.
Excited for the journey ahead!
@ki.se
October 10, 2025 at 7:27 AM
Yesterday marked my installation as Professor at Karolinska Institutet
I’m extremely grateful to my family, friends, and lab members who joined to celebrate this milestone.
Excited for the journey ahead!
@ki.se
I’m extremely grateful to my family, friends, and lab members who joined to celebrate this milestone.
Excited for the journey ahead!
@ki.se
Saddened to hear of Sir John Gurdon’s passing at 92. His pioneering work in nuclear reprogramming laid the foundation for modern stem cell biology. A true giant of developmental biology and an inspiration to generations.
Nobel Laureate (2012, with Shinya Yamanaka).
👇🏼being grilled by him :)
Nobel Laureate (2012, with Shinya Yamanaka).
👇🏼being grilled by him :)
October 9, 2025 at 7:18 AM
Saddened to hear of Sir John Gurdon’s passing at 92. His pioneering work in nuclear reprogramming laid the foundation for modern stem cell biology. A true giant of developmental biology and an inspiration to generations.
Nobel Laureate (2012, with Shinya Yamanaka).
👇🏼being grilled by him :)
Nobel Laureate (2012, with Shinya Yamanaka).
👇🏼being grilled by him :)
Thanks @societymucosalimm.bsky.social for highlighting our work!
Kudos to Francisca and Bianca for an amazing job!
Kudos to Francisca and Bianca for an amazing job!
SMI Member Eduardo Villablanca and colleagues review B cells in inflammatory bowel disease at Immunology Letters:
www.sciencedirect.com/science/arti...
#SMIMemberPaper #MucosalImmunology #Immunology
www.sciencedirect.com/science/arti...
#SMIMemberPaper #MucosalImmunology #Immunology
October 7, 2025 at 7:34 PM
Thanks @societymucosalimm.bsky.social for highlighting our work!
Kudos to Francisca and Bianca for an amazing job!
Kudos to Francisca and Bianca for an amazing job!
This is how we experience the Nobel Prize announcement every year, with excitement!
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
October 6, 2025 at 3:56 PM
This is how we experience the Nobel Prize announcement every year, with excitement!
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
This year was extra special, as we celebrated the immunology and Treg!
👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize
CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis | New England Journal of Medicine www.nejm.org/doi/full/10....
CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis | NEJM
In a patient with treatment-resistant ulcerative colitis, CD19 CAR T-cell therapy
led to drug-free remission and mucosal healing, suggesting that B-cell targeting may
offer a novel therapeutic ...
www.nejm.org
September 25, 2025 at 3:16 PM
CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis | New England Journal of Medicine www.nejm.org/doi/full/10....
Karolinska Institutet organizes an Installation Ceremony every fall, where new professors at KI are inaugurated and presented.
This year, it is my turn to be installed :) 😍
"Studying how inflammation starts and heals in the gut"
news.ki.se/studying-how...
This year, it is my turn to be installed :) 😍
"Studying how inflammation starts and heals in the gut"
news.ki.se/studying-how...
Studying how inflammation starts and heals in the gut
Inflammatory bowel disease affects millions of people worldwide and currently lacks a cure. Eduardo Villablanca studies how inflammation starts and heals in the intestines, with the aim to find new tr...
news.ki.se
September 25, 2025 at 7:42 AM
Karolinska Institutet organizes an Installation Ceremony every fall, where new professors at KI are inaugurated and presented.
This year, it is my turn to be installed :) 😍
"Studying how inflammation starts and heals in the gut"
news.ki.se/studying-how...
This year, it is my turn to be installed :) 😍
"Studying how inflammation starts and heals in the gut"
news.ki.se/studying-how...
Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures
#IBD
www.sciencedirect.com/science/arti...
#IBD
www.sciencedirect.com/science/arti...
Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures
A significant complication of Crohn’s disease (CD) is intestinal fibrosis, which narrows the bowel lumen to form a stricture. Creeping fat (CF) is the…
www.sciencedirect.com
September 17, 2025 at 6:35 PM
Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures
#IBD
www.sciencedirect.com/science/arti...
#IBD
www.sciencedirect.com/science/arti...
Reposted by Eduardo Villablanca
The gut microbiota directs vitamin A flux to regulate intestinal T cell development @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 11, 2025 at 3:50 AM
The gut microbiota directs vitamin A flux to regulate intestinal T cell development @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Extremely proud of @xinxinluo.bsky.social for winning the Dimitris N. Chorafas Prize 2025!
Awarded “for her groundbreaking work on inflammation, tissue damage & repair in the intestine, with innovative methods & impactful collaborations.”
So proud! 👏
news.ki.se/xinxin-luo-r...
@ki.se
#IBD
Awarded “for her groundbreaking work on inflammation, tissue damage & repair in the intestine, with innovative methods & impactful collaborations.”
So proud! 👏
news.ki.se/xinxin-luo-r...
@ki.se
#IBD
news.ki.se
September 9, 2025 at 9:40 AM
Extremely proud of @xinxinluo.bsky.social for winning the Dimitris N. Chorafas Prize 2025!
Awarded “for her groundbreaking work on inflammation, tissue damage & repair in the intestine, with innovative methods & impactful collaborations.”
So proud! 👏
news.ki.se/xinxin-luo-r...
@ki.se
#IBD
Awarded “for her groundbreaking work on inflammation, tissue damage & repair in the intestine, with innovative methods & impactful collaborations.”
So proud! 👏
news.ki.se/xinxin-luo-r...
@ki.se
#IBD
If you want to contribute to strategic areas of data-driven research within the Data-Driven Life Science (DDLS) program in Sweden, three of the DDLS research area expert groups are now seeking additional members!
Join us in helping shape data-driven research.
www.scilifelab.se/news/express...
Join us in helping shape data-driven research.
www.scilifelab.se/news/express...
Expression of interest call: Three of the DDLS research area expert groups now seek additional members
Are you an established expert within Data Driven Cell and Molecular biology, Epidemiology and biology of infection or Evolution and Biodiversity research, three of the four strategic areas for data-dr...
www.scilifelab.se
September 9, 2025 at 7:17 AM
If you want to contribute to strategic areas of data-driven research within the Data-Driven Life Science (DDLS) program in Sweden, three of the DDLS research area expert groups are now seeking additional members!
Join us in helping shape data-driven research.
www.scilifelab.se/news/express...
Join us in helping shape data-driven research.
www.scilifelab.se/news/express...
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity
Cell www.cell.com/cell/fulltex...
Cell www.cell.com/cell/fulltex...
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity
IL-25 treatment induces persistent adaptation of the small intestine, which is maintained
by ILC2s with functional and epigenetic qualities of immune memory. Effector-memory
ILC2s arise in multiple ti...
www.cell.com
September 5, 2025 at 8:01 PM
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity
Cell www.cell.com/cell/fulltex...
Cell www.cell.com/cell/fulltex...
🎉 Huge congratulations to @immunologyking.bsky.social & @maurogaya.bsky.social for an outstanding @embo.org workshop:
adaptive immunity in barrier tissues
Brilliant science, inspiring discussions, and friendships that make it one of the best!
adaptive immunity in barrier tissues
Brilliant science, inspiring discussions, and friendships that make it one of the best!
August 30, 2025 at 5:38 PM
🎉 Huge congratulations to @immunologyking.bsky.social & @maurogaya.bsky.social for an outstanding @embo.org workshop:
adaptive immunity in barrier tissues
Brilliant science, inspiring discussions, and friendships that make it one of the best!
adaptive immunity in barrier tissues
Brilliant science, inspiring discussions, and friendships that make it one of the best!
Great analogy to illustrate the question @carlanowosad.bsky.social is pursuing on her lab: how GC are form and how GC cells find their way to their specific locations
#embo workshop Basel
#immunalogy
#embo workshop Basel
#immunalogy
August 27, 2025 at 12:07 PM
Great analogy to illustrate the question @carlanowosad.bsky.social is pursuing on her lab: how GC are form and how GC cells find their way to their specific locations
#embo workshop Basel
#immunalogy
#embo workshop Basel
#immunalogy
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy: Cell www.cell.com/cell/fulltex...
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy
SPPL3 deletion modifies glycosylation on primary T cells, reducing allogeneic immune
responses without impairing tumor control by anti-CD19 allogeneic CAR-T cells. SPPL3-null,
TCR-sufficient anti-CD19...
www.cell.com
August 21, 2025 at 5:14 PM
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy: Cell www.cell.com/cell/fulltex...
#Bcells are emerging as key players in #IBD, far beyond a T-cell story.
From IgA protection to pro-inflammatory subsets, we highlight how understanding B cell diversity can unlock precise #Immunotherapy in #IBD.
Check Fran and Bianca's review 👇
doi.org/10.1016/j.im...
From IgA protection to pro-inflammatory subsets, we highlight how understanding B cell diversity can unlock precise #Immunotherapy in #IBD.
Check Fran and Bianca's review 👇
doi.org/10.1016/j.im...
August 20, 2025 at 2:11 PM
#Bcells are emerging as key players in #IBD, far beyond a T-cell story.
From IgA protection to pro-inflammatory subsets, we highlight how understanding B cell diversity can unlock precise #Immunotherapy in #IBD.
Check Fran and Bianca's review 👇
doi.org/10.1016/j.im...
From IgA protection to pro-inflammatory subsets, we highlight how understanding B cell diversity can unlock precise #Immunotherapy in #IBD.
Check Fran and Bianca's review 👇
doi.org/10.1016/j.im...
Thrilled to welcome Irene Salinas to our lab for her sabbatical! A true role model scientist who has already energized us with inspiring discussions in evolutionary immunology.
Looking forward more exciting scientific explorations and great conversations together
#ScienceCommunity #Collaboration
Looking forward more exciting scientific explorations and great conversations together
#ScienceCommunity #Collaboration
August 16, 2025 at 7:12 PM
Thrilled to welcome Irene Salinas to our lab for her sabbatical! A true role model scientist who has already energized us with inspiring discussions in evolutionary immunology.
Looking forward more exciting scientific explorations and great conversations together
#ScienceCommunity #Collaboration
Looking forward more exciting scientific explorations and great conversations together
#ScienceCommunity #Collaboration