Rodrigo Morales Castro
@ramoralescastro.bsky.social
Researcher at Karolinska Institutet @ki.se. Working on #zebrafish models of #inflammation and #regeneration
I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing
Promoting intestinal regeneration and enhancing mucosal healing have emerged as promising therapeutic alternatives for treating intestinal disorders t…
www.sciencedirect.com
May 14, 2025 at 9:35 AM
I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
www.sciencedirect.com/science/arti...
Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....
Reposted by Rodrigo Morales Castro
#LocationLocationLocation! Baghdadi, Kim &co show @science.org that intestinal stem cells #ISCs located at the bottom of the crypts sense a more rigid environment & activate PIEZO to tune their proliferation/differentiation maintaining gut physiology! doi.org/10.1126/scie...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...
doi.org
November 29, 2024 at 5:21 PM
#LocationLocationLocation! Baghdadi, Kim &co show @science.org that intestinal stem cells #ISCs located at the bottom of the crypts sense a more rigid environment & activate PIEZO to tune their proliferation/differentiation maintaining gut physiology! doi.org/10.1126/scie...
Reposted by Rodrigo Morales Castro
This is good advice:
'One piece of advice that stuck with me came from Mikael Pittet, who said, “Be patient in recruiting. A mistake in recruiting at the beginning can be fatal”. At the time, I thought, how difficult can that be?'
onlinelibrary.wiley.com/doi/10.1111/...
'One piece of advice that stuck with me came from Mikael Pittet, who said, “Be patient in recruiting. A mistake in recruiting at the beginning can be fatal”. At the time, I thought, how difficult can that be?'
onlinelibrary.wiley.com/doi/10.1111/...
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
This article reflects on the author's career journey, from beginnings in southern Chile to leading a research lab. It emphasizes the importance of relatable role models, resilience and leveraging per...
onlinelibrary.wiley.com
December 3, 2024 at 12:57 PM
This is good advice:
'One piece of advice that stuck with me came from Mikael Pittet, who said, “Be patient in recruiting. A mistake in recruiting at the beginning can be fatal”. At the time, I thought, how difficult can that be?'
onlinelibrary.wiley.com/doi/10.1111/...
'One piece of advice that stuck with me came from Mikael Pittet, who said, “Be patient in recruiting. A mistake in recruiting at the beginning can be fatal”. At the time, I thought, how difficult can that be?'
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Rodrigo Morales Castro
Very excited to share our latest work on the uncoupling of epithelial regeneration and tumorigenesis in the gut! nature.com/articles/s41...
November 20, 2024 at 11:41 PM
Very excited to share our latest work on the uncoupling of epithelial regeneration and tumorigenesis in the gut! nature.com/articles/s41...