Andrew Zalesky
@andrewzalesky.bsky.social
www.sysneuro.org
Melbourne, Australia
Melbourne, Australia
Reposted by Andrew Zalesky
My paper reviewing how different neurodegenerative diseases affect autonomic function was just published.
Autonomic dysfunction in neurodegenerative disease — a Review by Mara Mather
www.nature.com/articles/s41...
@maramather.bsky.social
#neuroscience
www.nature.com/articles/s41...
@maramather.bsky.social
#neuroscience
Autonomic dysfunction in neurodegenerative disease - Nature Reviews Neuroscience
Neurodegenerative disorders are commonly associated with autonomic dysfunction as well as the more well-known cognitive and motor effects. In this Review, Mather describes how properties of neurons in...
www.nature.com
April 10, 2025 at 12:54 AM
My paper reviewing how different neurodegenerative diseases affect autonomic function was just published.
Reposted by Andrew Zalesky
Our cover is now live at Nature Neuroscience @natureneuro.bsky.social !
April 8, 2025 at 2:07 AM
Our cover is now live at Nature Neuroscience @natureneuro.bsky.social !
Reposted by Andrew Zalesky
Absolutely incredible work by Davide Momi, John Griffiths,and a stellar team of neuroscientists with a multidimensional view of brain dynamics.
This work gives us a WHOLE BRAIN map of excitability.
www.nature.com/articles/s41...
This work gives us a WHOLE BRAIN map of excitability.
www.nature.com/articles/s41...
Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks - Nature Communications
How brain networks organize and interact based on their hierarchical position remains poorly understood. Momi, Wang et al find that high-order brain networks show stronger responses to stimulation and...
www.nature.com
April 6, 2025 at 12:56 PM
Absolutely incredible work by Davide Momi, John Griffiths,and a stellar team of neuroscientists with a multidimensional view of brain dynamics.
This work gives us a WHOLE BRAIN map of excitability.
www.nature.com/articles/s41...
This work gives us a WHOLE BRAIN map of excitability.
www.nature.com/articles/s41...
Reposted by Andrew Zalesky
Happy to share that our article “Human lifespan changes in the brain’s functional connectome” is now published online at Nature Neuroscience @natureneuro.bsky.social !
Many thanks to all collaborators & data contributors, and the editor team & reviewers!
www.nature.com/articles/s41...
Many thanks to all collaborators & data contributors, and the editor team & reviewers!
www.nature.com/articles/s41...
Human lifespan changes in the brain’s functional connectome - Nature Neuroscience
Sun et al. report human lifespan changes in the brain’s functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative...
www.nature.com
April 4, 2025 at 5:48 AM
Happy to share that our article “Human lifespan changes in the brain’s functional connectome” is now published online at Nature Neuroscience @natureneuro.bsky.social !
Many thanks to all collaborators & data contributors, and the editor team & reviewers!
www.nature.com/articles/s41...
Many thanks to all collaborators & data contributors, and the editor team & reviewers!
www.nature.com/articles/s41...
Reposted by Andrew Zalesky
When we use TMS to treat depression, we think it alters neural activity in a deep brain structure known as the subgenual anterior cingulate (sgACC). But this is hard to test directly, until our preprint with @coreykeller.bsky.social, @neuro-engineer.bsky.social, Nick Trapp, and Aaron Boes (UIowa) 1/
DLPFC Stimulation Suppresses High-Frequency Neural Activity in the Human sgACC
Transcranial magnetic stimulation (TMS) to the dorsolateral prefrontal cortex (DLPFC) is hypothesized to relieve symptoms of depression by inhibiting activity in the subgenual anterior cingulate corte...
www.biorxiv.org
April 3, 2025 at 6:15 PM
When we use TMS to treat depression, we think it alters neural activity in a deep brain structure known as the subgenual anterior cingulate (sgACC). But this is hard to test directly, until our preprint with @coreykeller.bsky.social, @neuro-engineer.bsky.social, Nick Trapp, and Aaron Boes (UIowa) 1/
Reposted by Andrew Zalesky
Study human brain structure and function with our new open access 7T MRI dataset
led by superstar scientist @donnagift.bsky.social ↙️
led by superstar scientist @donnagift.bsky.social ↙️
Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
Multimodal precision MRI of the individual human brain at ultra-high fields - Scientific Data
Scientific Data - Multimodal precision MRI of the individual human brain at ultra-high fields
www.nature.com
March 30, 2025 at 3:39 PM
Study human brain structure and function with our new open access 7T MRI dataset
led by superstar scientist @donnagift.bsky.social ↙️
led by superstar scientist @donnagift.bsky.social ↙️
Reposted by Andrew Zalesky
🚨We're hiring another tenure-track at McGill University: focus on brain-body science! 👇
mcgill.wd3.myworkdayjobs.com/en-US/mcgill...
mcgill.wd3.myworkdayjobs.com/en-US/mcgill...
April 2, 2025 at 9:31 PM
🚨We're hiring another tenure-track at McGill University: focus on brain-body science! 👇
mcgill.wd3.myworkdayjobs.com/en-US/mcgill...
mcgill.wd3.myworkdayjobs.com/en-US/mcgill...
SAVE THE DATE
2025 OHBM Oz meeting
November 12, 2025
Melbourne
2025 OHBM Oz meeting
November 12, 2025
Melbourne
🚨 We are excited to announce that the next OHBM Australia meeting will be in Melbourne on Wednesday, 12th November, 2025! Stay tuned for more details 👀
April 3, 2025 at 2:14 AM
SAVE THE DATE
2025 OHBM Oz meeting
November 12, 2025
Melbourne
2025 OHBM Oz meeting
November 12, 2025
Melbourne
Reposted by Andrew Zalesky
We are hiring! We're looking for a Research Office to help out with recruitment & assessment on a large-scale study looking at the relationship between brain imaging measures and psychopathology. Please forward this link to anyone who might be interested:
careers.pageuppeople.com/513/ci/en/jo...
careers.pageuppeople.com/513/ci/en/jo...
Monash University - Sign In
Sign in with your account to access PageUp
careers.pageuppeople.com
April 2, 2025 at 9:23 PM
We are hiring! We're looking for a Research Office to help out with recruitment & assessment on a large-scale study looking at the relationship between brain imaging measures and psychopathology. Please forward this link to anyone who might be interested:
careers.pageuppeople.com/513/ci/en/jo...
careers.pageuppeople.com/513/ci/en/jo...
Reposted by Andrew Zalesky
📢 Exciting news! OHBM is partnering with United Airlines for our upcoming event. Enjoy special rates on flights to Brisbane, Australia, from June 21 to July 1, 2025. For more information, visit the link in comments! #OHBM2025 #TravelwithUnited
January 20, 2025 at 12:00 PM
📢 Exciting news! OHBM is partnering with United Airlines for our upcoming event. Enjoy special rates on flights to Brisbane, Australia, from June 21 to July 1, 2025. For more information, visit the link in comments! #OHBM2025 #TravelwithUnited
Reposted by Andrew Zalesky
June 2025 is an exciting month for Psychological and Brain Sciences in Australia! In addition to our joint meeting between EPC and APCV, the Organisation for Human Brain Mapping meets in Brisbane the following week. See below for a schedule of events linked with OHBM.
Check out the schedule of events linked with OHBM 2025
- Brain connectivity workshop, June 20-22
- Hackathon, June 21-23
- Neurodesk, June 21
- Brain gradients, June 23
- Precision network therapeutics, June 29
Register now!
We look forward to welcoming you to Brisbane!
@ohbmofficial.bsky.social
- Brain connectivity workshop, June 20-22
- Hackathon, June 21-23
- Neurodesk, June 21
- Brain gradients, June 23
- Precision network therapeutics, June 29
Register now!
We look forward to welcoming you to Brisbane!
@ohbmofficial.bsky.social
February 3, 2025 at 6:54 AM
June 2025 is an exciting month for Psychological and Brain Sciences in Australia! In addition to our joint meeting between EPC and APCV, the Organisation for Human Brain Mapping meets in Brisbane the following week. See below for a schedule of events linked with OHBM.
Reposted by Andrew Zalesky
How is the body experienced in mental health conditions? 🧠🫀🫁
Our (@gabmackie.bsky.social) new paper in eClinicalMedicine explores lived experiences and patient priorities for interoception research. 🧵1/n
www.sciencedirect.com/science/arti...
Our (@gabmackie.bsky.social) new paper in eClinicalMedicine explores lived experiences and patient priorities for interoception research. 🧵1/n
www.sciencedirect.com/science/arti...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
April 1, 2025 at 4:48 PM
How is the body experienced in mental health conditions? 🧠🫀🫁
Our (@gabmackie.bsky.social) new paper in eClinicalMedicine explores lived experiences and patient priorities for interoception research. 🧵1/n
www.sciencedirect.com/science/arti...
Our (@gabmackie.bsky.social) new paper in eClinicalMedicine explores lived experiences and patient priorities for interoception research. 🧵1/n
www.sciencedirect.com/science/arti...
Reposted by Andrew Zalesky
Workshop contributors had a variety of initial thoughts in response to the question: “how are bodily signals related to your mental health?” This was conducted prior to any detailed information about the aims of the workshop, or the field's perceived notions of interoception. 🧵4/n
April 1, 2025 at 4:48 PM
Workshop contributors had a variety of initial thoughts in response to the question: “how are bodily signals related to your mental health?” This was conducted prior to any detailed information about the aims of the workshop, or the field's perceived notions of interoception. 🧵4/n
Reposted by Andrew Zalesky
Myelinated fiber labeling and orientation mapping of the human brain with light-sheet fluorescence microscopy | bioRxiv www.biorxiv.org/content/10.1...
April 2, 2025 at 12:08 AM
Myelinated fiber labeling and orientation mapping of the human brain with light-sheet fluorescence microscopy | bioRxiv www.biorxiv.org/content/10.1...
Getting excited about OHBM25. Not far now!
Features an AMAZING schedule of keynotes, educational workshops, symposia, networking events as well as several satellite meetings!
Don't forget to register before April 15 for the EBR!
@ohbmofficial.bsky.social
www.humanbrainmapping.org/i4a/pages/in...
Features an AMAZING schedule of keynotes, educational workshops, symposia, networking events as well as several satellite meetings!
Don't forget to register before April 15 for the EBR!
@ohbmofficial.bsky.social
www.humanbrainmapping.org/i4a/pages/in...
April 1, 2025 at 11:20 AM
Getting excited about OHBM25. Not far now!
Features an AMAZING schedule of keynotes, educational workshops, symposia, networking events as well as several satellite meetings!
Don't forget to register before April 15 for the EBR!
@ohbmofficial.bsky.social
www.humanbrainmapping.org/i4a/pages/in...
Features an AMAZING schedule of keynotes, educational workshops, symposia, networking events as well as several satellite meetings!
Don't forget to register before April 15 for the EBR!
@ohbmofficial.bsky.social
www.humanbrainmapping.org/i4a/pages/in...
The brain-heart connection:
Shared Pathways of Brain and Cardiovascular Health
medicalxpress.com/news/2025-02...
www.jneurosci.org/content/45/8...
Shared Pathways of Brain and Cardiovascular Health
medicalxpress.com/news/2025-02...
www.jneurosci.org/content/45/8...
February 25, 2025 at 1:35 AM
The brain-heart connection:
Shared Pathways of Brain and Cardiovascular Health
medicalxpress.com/news/2025-02...
www.jneurosci.org/content/45/8...
Shared Pathways of Brain and Cardiovascular Health
medicalxpress.com/news/2025-02...
www.jneurosci.org/content/45/8...
Reposted by Andrew Zalesky
We've updated our mouse connectome-based ID paper using simultaneous Ca2+ imaging and fMRI connectivity data--check it out!
www.biorxiv.org/content/10.1...
Shoutout to all! @francimandi.bsky.social, @toddc.bsky.social, @mallarchak.bsky.social, @richardfbetzel.bsky.social, and many others! 1/2
www.biorxiv.org/content/10.1...
Shoutout to all! @francimandi.bsky.social, @toddc.bsky.social, @mallarchak.bsky.social, @richardfbetzel.bsky.social, and many others! 1/2
Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI
Individual differences in neuroimaging are of interest to clinical and cognitive neuroscientists based on their potential for guiding the personalized treatment of various heterogeneous neurological c...
www.biorxiv.org
February 21, 2025 at 6:13 PM
We've updated our mouse connectome-based ID paper using simultaneous Ca2+ imaging and fMRI connectivity data--check it out!
www.biorxiv.org/content/10.1...
Shoutout to all! @francimandi.bsky.social, @toddc.bsky.social, @mallarchak.bsky.social, @richardfbetzel.bsky.social, and many others! 1/2
www.biorxiv.org/content/10.1...
Shoutout to all! @francimandi.bsky.social, @toddc.bsky.social, @mallarchak.bsky.social, @richardfbetzel.bsky.social, and many others! 1/2
Reposted by Andrew Zalesky
Ever heard of EEG microstates? Usually defined as cluster centres of topography, the dynamics of MS sequences are referred to as "syntaxes". Our new review discusses syntax methods and show how they could be better associated with the underlying EEG signal: 🧵👇 www.sciencedirect.com/science/arti...
February 21, 2025 at 8:59 AM
Ever heard of EEG microstates? Usually defined as cluster centres of topography, the dynamics of MS sequences are referred to as "syntaxes". Our new review discusses syntax methods and show how they could be better associated with the underlying EEG signal: 🧵👇 www.sciencedirect.com/science/arti...
Reposted by Andrew Zalesky
Reposted by Andrew Zalesky
For data defined on top of a graph/network (e.g. annotations on brain graphs), it is efficient to decompose them with filters that adapt to the spectral characteristics of the data at hand | w. @dimitrivdv.bsky.social @rikossenkoppele.bsky.social + C-F Westin
February 19, 2025 at 11:16 AM
For data defined on top of a graph/network (e.g. annotations on brain graphs), it is efficient to decompose them with filters that adapt to the spectral characteristics of the data at hand | w. @dimitrivdv.bsky.social @rikossenkoppele.bsky.social + C-F Westin
So much research focusses on using brain connectivity to predict an individual's cognition, IQ, disease status, etc.
BUT what about the inverse problem?
Can personal data be used to build an individual's whole connectome?
YES - with AI:
www.biorxiv.org/content/10.1...
BUT what about the inverse problem?
Can personal data be used to build an individual's whole connectome?
YES - with AI:
www.biorxiv.org/content/10.1...
February 15, 2025 at 12:45 AM
So much research focusses on using brain connectivity to predict an individual's cognition, IQ, disease status, etc.
BUT what about the inverse problem?
Can personal data be used to build an individual's whole connectome?
YES - with AI:
www.biorxiv.org/content/10.1...
BUT what about the inverse problem?
Can personal data be used to build an individual's whole connectome?
YES - with AI:
www.biorxiv.org/content/10.1...
Reposted by Andrew Zalesky
🚀 Explore Spectral Normative Modeling in action!
We’ve built an interactive visualization showcasing high-resolution normative reference ranges generated via SNM.
🔗 Try it here: sina-mansour.github.io/normative_br...
We’ve built an interactive visualization showcasing high-resolution normative reference ranges generated via SNM.
🔗 Try it here: sina-mansour.github.io/normative_br...
February 13, 2025 at 5:03 AM
🚀 Explore Spectral Normative Modeling in action!
We’ve built an interactive visualization showcasing high-resolution normative reference ranges generated via SNM.
🔗 Try it here: sina-mansour.github.io/normative_br...
We’ve built an interactive visualization showcasing high-resolution normative reference ranges generated via SNM.
🔗 Try it here: sina-mansour.github.io/normative_br...
TMS is delivered to the DLPFC in depression to modulate SGC activity
But axons linking DLPFC and SGC are absent.
How then does TMS stimulation delivered to the DLPFC modulate SGC activity?
Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
But axons linking DLPFC and SGC are absent.
How then does TMS stimulation delivered to the DLPFC modulate SGC activity?
Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
Caio is having a good day. Another preprint on which he's first author -- this time, describing pathways through the connectome for indirectly stimulating subgenual cingulate cortex in the context of depression.
Neuroanatomical pathways of TMS therapy for depression
www.medrxiv.org/content/10.1...
Neuroanatomical pathways of TMS therapy for depression
www.medrxiv.org/content/10.1...
February 13, 2025 at 4:06 AM
TMS is delivered to the DLPFC in depression to modulate SGC activity
But axons linking DLPFC and SGC are absent.
How then does TMS stimulation delivered to the DLPFC modulate SGC activity?
Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
But axons linking DLPFC and SGC are absent.
How then does TMS stimulation delivered to the DLPFC modulate SGC activity?
Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
Reposted by Andrew Zalesky
Can damage to a specific brain circuit cause psychosis? New paper out today by @andrewpines.bsky.social @shansiddiqi.bsky.social says Yes! Hub of the circuit is in the hippocampus - great alignment with NMDA encephalitis. @braincircuits.bsky.social
What brain regions are involved in causing psychotic symptoms?
Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients!
1/n🧵
Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients!
1/n🧵
February 13, 2025 at 1:34 AM
Can damage to a specific brain circuit cause psychosis? New paper out today by @andrewpines.bsky.social @shansiddiqi.bsky.social says Yes! Hub of the circuit is in the hippocampus - great alignment with NMDA encephalitis. @braincircuits.bsky.social
Reposted by Andrew Zalesky
Synaptome architecture shapes regional dynamics in the mouse brain | www.biorxiv.org/content/10.1...
Led by Justine Hansen
Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
Led by Justine Hansen
Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
February 12, 2025 at 6:23 PM
Synaptome architecture shapes regional dynamics in the mouse brain | www.biorxiv.org/content/10.1...
Led by Justine Hansen
Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
Led by Justine Hansen
Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️