Harry H Behjat
@aitchbi.bsky.social
imaging neuroscience • data science on graphs • brain structure-function-pathology interplay • spatial methods • MRI PET • Alzheimer’s disease
🌐 https://linktr.ee/aitchbi
🌐 https://linktr.ee/aitchbi
Pinned
Harry H Behjat
@aitchbi.bsky.social
· Oct 7
does brain connectivity drive spread of pathological proteins in Alzheimer’s disease?
✨ preprint: www.biorxiv.org/content/10.1...
if the question intrigues you, please read on 🧵⤵️
✨ preprint: www.biorxiv.org/content/10.1...
if the question intrigues you, please read on 🧵⤵️
Reposted by Harry H Behjat
I uploaded the lecture I gave on hidden multivariate pattern methods in M/EEG at the #practicalMEEG2025 conference (wonderfully organized by @cuttingeeg.bsky.social).
youtu.be/MgrqA7jMSBw
It's just an introduction but maybe some will find it useful :)
youtu.be/MgrqA7jMSBw
It's just an introduction but maybe some will find it useful :)
HMP lecture #practicalMEEG2025
YouTube video by Gabriel Weindel
youtu.be
November 4, 2025 at 11:07 AM
I uploaded the lecture I gave on hidden multivariate pattern methods in M/EEG at the #practicalMEEG2025 conference (wonderfully organized by @cuttingeeg.bsky.social).
youtu.be/MgrqA7jMSBw
It's just an introduction but maybe some will find it useful :)
youtu.be/MgrqA7jMSBw
It's just an introduction but maybe some will find it useful :)
Reposted by Harry H Behjat
Please repost! I am looking for a PhD candidate in the area of Computational Cognitive Neuroscience to start in early 2026.
The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social.
Please apply here until Nov 25:
www.uni-giessen.de/de/ueber-uns...
The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social.
Please apply here until Nov 25:
www.uni-giessen.de/de/ueber-uns...
November 4, 2025 at 1:57 PM
Please repost! I am looking for a PhD candidate in the area of Computational Cognitive Neuroscience to start in early 2026.
The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social.
Please apply here until Nov 25:
www.uni-giessen.de/de/ueber-uns...
The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social.
Please apply here until Nov 25:
www.uni-giessen.de/de/ueber-uns...
Reposted by Harry H Behjat
🚨Paper Out!
Systematic Review & Meta-analysis of ALS Fluid Biomarkers
🧵Key findings:
• NfL leads for both diagnosis (AUC 0.81–0.92) & prognosis (HR 2.8–4.3)
• CSF chitinases, p-tau/t-tau: moderate values
• Marked heterogeneity
onlinelibrary.wiley.com/doi/10.1111/...
Systematic Review & Meta-analysis of ALS Fluid Biomarkers
🧵Key findings:
• NfL leads for both diagnosis (AUC 0.81–0.92) & prognosis (HR 2.8–4.3)
• CSF chitinases, p-tau/t-tau: moderate values
• Marked heterogeneity
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
October 29, 2025 at 12:32 PM
🚨Paper Out!
Systematic Review & Meta-analysis of ALS Fluid Biomarkers
🧵Key findings:
• NfL leads for both diagnosis (AUC 0.81–0.92) & prognosis (HR 2.8–4.3)
• CSF chitinases, p-tau/t-tau: moderate values
• Marked heterogeneity
onlinelibrary.wiley.com/doi/10.1111/...
Systematic Review & Meta-analysis of ALS Fluid Biomarkers
🧵Key findings:
• NfL leads for both diagnosis (AUC 0.81–0.92) & prognosis (HR 2.8–4.3)
• CSF chitinases, p-tau/t-tau: moderate values
• Marked heterogeneity
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Harry H Behjat
We just advertised the Hooke Fellowships for exceptional researchers (typically after their first post-doc).
You are completely free to set up your own research agenda for three years.
RT please
my.corehr.com/pls/uoxrecru...
You are completely free to set up your own research agenda for three years.
RT please
my.corehr.com/pls/uoxrecru...
my.corehr.com
October 21, 2025 at 5:38 PM
We just advertised the Hooke Fellowships for exceptional researchers (typically after their first post-doc).
You are completely free to set up your own research agenda for three years.
RT please
my.corehr.com/pls/uoxrecru...
You are completely free to set up your own research agenda for three years.
RT please
my.corehr.com/pls/uoxrecru...
Reposted by Harry H Behjat
Quantifying the compressibility of the human brain | arxiv.org/abs/2510.16327
October 21, 2025 at 2:51 AM
Quantifying the compressibility of the human brain | arxiv.org/abs/2510.16327
Reposted by Harry H Behjat
The illusion of illusions
One of the oldest myths in human history is that the Parthenon was cleverly built with curves so that it looks straight, to correct some visual illusions
In this paper I demonstrate that there are NO optical corrections in the Parthenon
arxiv.org/abs/2510.16831. [1/n]
One of the oldest myths in human history is that the Parthenon was cleverly built with curves so that it looks straight, to correct some visual illusions
In this paper I demonstrate that there are NO optical corrections in the Parthenon
arxiv.org/abs/2510.16831. [1/n]
The illusion of illusions: There are no optical corrections in the Parthenon
One of the oldest and most enduring myths in human history is the belief that the Parthenon was cleverly designed with various curved structures and sizes in order to correct optical illusions, and th...
arxiv.org
October 21, 2025 at 6:40 AM
The illusion of illusions
One of the oldest myths in human history is that the Parthenon was cleverly built with curves so that it looks straight, to correct some visual illusions
In this paper I demonstrate that there are NO optical corrections in the Parthenon
arxiv.org/abs/2510.16831. [1/n]
One of the oldest myths in human history is that the Parthenon was cleverly built with curves so that it looks straight, to correct some visual illusions
In this paper I demonstrate that there are NO optical corrections in the Parthenon
arxiv.org/abs/2510.16831. [1/n]
Reposted by Harry H Behjat
Reposted by Harry H Behjat
🧠 Why do some brains age faster than others?
🧬 Our new Nature Aging study of over 56,000 participants explores the genetics of the “brain age gap” — the difference between your brain’s biological and chronological age.
nature.com/articles/s43587-025-00962-7
Thread below 👇
🧬 Our new Nature Aging study of over 56,000 participants explores the genetics of the “brain age gap” — the difference between your brain’s biological and chronological age.
nature.com/articles/s43587-025-00962-7
Thread below 👇
Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health - Nature Aging
This genomic study of magnetic resonance imaging-based brain age in 56,348 people identifies 59 genetic loci, links brain aging to mental and physical health, and suggests high blood pressure and type 2 diabetes as causal factors of brain aging.
nature.com
October 7, 2025 at 9:38 AM
🧠 Why do some brains age faster than others?
🧬 Our new Nature Aging study of over 56,000 participants explores the genetics of the “brain age gap” — the difference between your brain’s biological and chronological age.
nature.com/articles/s43587-025-00962-7
Thread below 👇
🧬 Our new Nature Aging study of over 56,000 participants explores the genetics of the “brain age gap” — the difference between your brain’s biological and chronological age.
nature.com/articles/s43587-025-00962-7
Thread below 👇
Reposted by Harry H Behjat
Is resting-state functional connectivity (rsFC), cortical thickness (CT), or cortical volume more effective at capturing sex and gender differences in the brains of preadolescents?
Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.
Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.
October 7, 2025 at 7:02 PM
Is resting-state functional connectivity (rsFC), cortical thickness (CT), or cortical volume more effective at capturing sex and gender differences in the brains of preadolescents?
Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.
Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.
Reposted by Harry H Behjat
1000s of studies have been published mapping neuroanatomical changes in psychiatric disorders. Can we ever converge on robust disease phenotypes? Our latest PP led by Trang Cao in a huge collab effort investigates this question...
@nsb-lab.bsky.social
@nsb-lab.bsky.social
July 10, 2025 at 11:28 PM
1000s of studies have been published mapping neuroanatomical changes in psychiatric disorders. Can we ever converge on robust disease phenotypes? Our latest PP led by Trang Cao in a huge collab effort investigates this question...
@nsb-lab.bsky.social
@nsb-lab.bsky.social
Reposted by Harry H Behjat
Excited to share my first preprint investigating the feasibility and reliability of using precision RSFC in people with Parkinson’s disease! 🧠👇
📄: go.illinois.edu/PDfeasibility
🧵 Thread ⬇️ 1/12
📄: go.illinois.edu/PDfeasibility
🧵 Thread ⬇️ 1/12
July 9, 2025 at 4:33 PM
Excited to share my first preprint investigating the feasibility and reliability of using precision RSFC in people with Parkinson’s disease! 🧠👇
📄: go.illinois.edu/PDfeasibility
🧵 Thread ⬇️ 1/12
📄: go.illinois.edu/PDfeasibility
🧵 Thread ⬇️ 1/12
Reposted by Harry H Behjat
Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
September 30, 2025 at 7:39 PM
Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Harry H Behjat
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f
Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience
➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?
Check out what we found!
🧵1/n
Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience
➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?
Check out what we found!
🧵1/n
September 10, 2025 at 3:08 PM
Reposted by Harry H Behjat
🔥Recent advances in #neuroimaging of #Alzheimers disease 🧠✨
dx.doi.org/10.1002/alz....
➡️ Valuable resource for both researchers & clinicians!
➡️ ATNIV biomarkers, staging, connectomics & more
➡️ Plus: how are sex & country represented in first/last authorship?
@istaart.bsky.social Neuroimaging PIA
dx.doi.org/10.1002/alz....
➡️ Valuable resource for both researchers & clinicians!
➡️ ATNIV biomarkers, staging, connectomics & more
➡️ Plus: how are sex & country represented in first/last authorship?
@istaart.bsky.social Neuroimaging PIA
September 9, 2025 at 7:38 PM
🔥Recent advances in #neuroimaging of #Alzheimers disease 🧠✨
dx.doi.org/10.1002/alz....
➡️ Valuable resource for both researchers & clinicians!
➡️ ATNIV biomarkers, staging, connectomics & more
➡️ Plus: how are sex & country represented in first/last authorship?
@istaart.bsky.social Neuroimaging PIA
dx.doi.org/10.1002/alz....
➡️ Valuable resource for both researchers & clinicians!
➡️ ATNIV biomarkers, staging, connectomics & more
➡️ Plus: how are sex & country represented in first/last authorship?
@istaart.bsky.social Neuroimaging PIA
does brain connectivity drive spread of pathological proteins in Alzheimer’s disease?
✨ preprint: www.biorxiv.org/content/10.1...
if the question intrigues you, please read on 🧵⤵️
✨ preprint: www.biorxiv.org/content/10.1...
if the question intrigues you, please read on 🧵⤵️
October 7, 2025 at 8:59 AM
does brain connectivity drive spread of pathological proteins in Alzheimer’s disease?
✨ preprint: www.biorxiv.org/content/10.1...
if the question intrigues you, please read on 🧵⤵️
✨ preprint: www.biorxiv.org/content/10.1...
if the question intrigues you, please read on 🧵⤵️
Reposted by Harry H Behjat
Patient-specific functional brain architecture explains cortical patterns of tau PET in Alzheimer's disease https://www.biorxiv.org/content/10.1101/2025.10.02.679969v1
October 4, 2025 at 12:17 AM
Patient-specific functional brain architecture explains cortical patterns of tau PET in Alzheimer's disease https://www.biorxiv.org/content/10.1101/2025.10.02.679969v1
Reposted by Harry H Behjat
Quantum-like dynamics in the human brain https://www.biorxiv.org/content/10.1101/2025.10.02.680057v1
October 4, 2025 at 12:16 AM
Quantum-like dynamics in the human brain https://www.biorxiv.org/content/10.1101/2025.10.02.680057v1
Reposted by Harry H Behjat
🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus
Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)
Led by @jordandekraker.bsky.social
docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
HippoMaps: multiscale cartography of the human hippocampus
Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)
Led by @jordandekraker.bsky.social
docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
October 2, 2025 at 11:50 AM
🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus
Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)
Led by @jordandekraker.bsky.social
docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
HippoMaps: multiscale cartography of the human hippocampus
Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)
Led by @jordandekraker.bsky.social
docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
Reposted by Harry H Behjat
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
September 19, 2025 at 8:37 PM
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Reposted by Harry H Behjat
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health
Major mental disorders are increasingly understood as disorders of brain development. Large and heterogeneous samples are required to define generalizable links between brain development and psychopat...
doi.org
September 22, 2025 at 9:51 PM
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
Reposted by Harry H Behjat
Interested in hippocampal dynamics and their interactions with cortical rhythms?
Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo)
www.biorxiv.org/content/10.1...
Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo)
www.biorxiv.org/content/10.1...
September 14, 2025 at 11:35 AM
Interested in hippocampal dynamics and their interactions with cortical rhythms?
Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo)
www.biorxiv.org/content/10.1...
Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo)
www.biorxiv.org/content/10.1...
Reposted by Harry H Behjat
I'm thrilled that our paper "Personalised regional modelling predicts tau progression in the human brain" is finally published in PLoS Biology!
Here's a short thread about the main findings of the paper...
Here's a short thread about the main findings of the paper...
Accumulation of aggregated tau shows a complex spatio-temporal pattern during #AlzheimersDisease, but why? @pavanchaggar.bsky.social @alaingoriely.bsky.social &co describes #TauProtein dynamics in AD, showing stage-specific shifts in production & transport @plosbiology.org 🧪 plos.io/4kNA6vX
![Simulated transport and production dynamics in the local FKPP model. Left: Simulation from the local FKPP model using carrying capacities derived from Gaussian mixture models (shown top right). Each line in the middle panel represents the SUVR trajectory of one DK atlas brain region. Values at time points years are projected onto a cortical rendering in the top panel. Each line in the bottom panel represents concentration averaged over Braak regions. Top right: Two component Gaussian mixture model fit to a multi-cohort tau PET dataset [24] and data from ADNI for right inferior temporal lobe. Bottom right: Right hemisphere cortical rendering of the SUVR carrying capacities as determined through Gaussian mixture modelling.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreidvyyx2seiwefemwo6bvbfw6q7chuhw627ppxyixeminyueea7tzq@jpeg)
August 11, 2025 at 2:39 PM
I'm thrilled that our paper "Personalised regional modelling predicts tau progression in the human brain" is finally published in PLoS Biology!
Here's a short thread about the main findings of the paper...
Here's a short thread about the main findings of the paper...
Reposted by Harry H Behjat
Latest work at #EUSIPCO25!🚀
We bring Topological Signal Processing to the brain 🧠 — showing that edge-based approaches outperform classical GSP in task decoding.
Great collab with M.Nurisso & @lordgrilo.bsky.social 🙌
Paper 👉 eusipco2025.org/wp-content/u...
#Neuroimaging #SignalProcessing #TSP
We bring Topological Signal Processing to the brain 🧠 — showing that edge-based approaches outperform classical GSP in task decoding.
Great collab with M.Nurisso & @lordgrilo.bsky.social 🙌
Paper 👉 eusipco2025.org/wp-content/u...
#Neuroimaging #SignalProcessing #TSP
September 9, 2025 at 10:25 AM
Latest work at #EUSIPCO25!🚀
We bring Topological Signal Processing to the brain 🧠 — showing that edge-based approaches outperform classical GSP in task decoding.
Great collab with M.Nurisso & @lordgrilo.bsky.social 🙌
Paper 👉 eusipco2025.org/wp-content/u...
#Neuroimaging #SignalProcessing #TSP
We bring Topological Signal Processing to the brain 🧠 — showing that edge-based approaches outperform classical GSP in task decoding.
Great collab with M.Nurisso & @lordgrilo.bsky.social 🙌
Paper 👉 eusipco2025.org/wp-content/u...
#Neuroimaging #SignalProcessing #TSP
Reposted by Harry H Behjat
Assistant professor position at Linköping University, Sweden, with great startup package
Machine learning and AI for precision medicine and diagnostics
www.scilifelab.se/career/assis...
Machine learning and AI for precision medicine and diagnostics
www.scilifelab.se/career/assis...
Assistant Professor in Data-driven precision medicine and diagnostics
We have the power of over 40,000 students and co-workers. Students who provide hope for the future. Co-workers who contribute to Linköping University meeting challenges of today. Our fundamental value...
www.scilifelab.se
September 29, 2025 at 4:50 PM
Assistant professor position at Linköping University, Sweden, with great startup package
Machine learning and AI for precision medicine and diagnostics
www.scilifelab.se/career/assis...
Machine learning and AI for precision medicine and diagnostics
www.scilifelab.se/career/assis...
Reposted by Harry H Behjat
This is a major milestone for @sylviavilleneuve.bsky.social & PREVENT-AD. Their vision & dedication have led to a series of impactful studies & high-profile publications, and the future promises insights as this unique dataset continues to grow.
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
The PREVENT‐AD cohort: Accelerating Alzheimer's disease research and treatment in Canada and beyond
The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal older ...
alz-journals.onlinelibrary.wiley.com
September 29, 2025 at 5:24 PM
This is a major milestone for @sylviavilleneuve.bsky.social & PREVENT-AD. Their vision & dedication have led to a series of impactful studies & high-profile publications, and the future promises insights as this unique dataset continues to grow.
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...