Corey Horien
@coreyhorien.bsky.social
Research track resident in psychiatry at UPenn | PennLINC
Neuroimaging, development, precision psychiatry
Neuroimaging, development, precision psychiatry
Reposted by Corey Horien
Very cool work from my friends and colleagues @actlab.bsky.social and Damon Clark - I am lucky to get to hang out with them at @wutsaiyale.bsky.social
Humans can use positive and negative spectrotemporal correlations to detect rising and falling pitch
Humans can use positive and negative spectrotemporal correlations to detect rising and falling pitch
Nature Human Behaviour, Published online: 09 February 2026; doi:10.1038/s41562-025-02371-7Vaziri et al. examined how humans detect changes in auditory pitch, revealing that listeners rely on correlations in sound intensity over frequency and time, processing that is reminiscent of visual motion detection.
dlvr.it
February 9, 2026 at 6:26 PM
Very cool work from my friends and colleagues @actlab.bsky.social and Damon Clark - I am lucky to get to hang out with them at @wutsaiyale.bsky.social
Reposted by Corey Horien
𝗧𝗿𝗮𝘃𝗲𝗹𝗶𝗻𝗴 𝘄𝗮𝘃𝗲𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻
"Cortical traveling waves in time and space: Physics, physiology, and psychology" is going to the top of the list!
doi.org/10.1016/j.ne...
#neuroskyence
"Cortical traveling waves in time and space: Physics, physiology, and psychology" is going to the top of the list!
doi.org/10.1016/j.ne...
#neuroskyence
February 9, 2026 at 10:55 PM
𝗧𝗿𝗮𝘃𝗲𝗹𝗶𝗻𝗴 𝘄𝗮𝘃𝗲𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻
"Cortical traveling waves in time and space: Physics, physiology, and psychology" is going to the top of the list!
doi.org/10.1016/j.ne...
#neuroskyence
"Cortical traveling waves in time and space: Physics, physiology, and psychology" is going to the top of the list!
doi.org/10.1016/j.ne...
#neuroskyence
Reposted by Corey Horien
New research out in @nature.com delineates two replicable axes of human white matter development ft. @audreycluo.bsky.social & @ted-satterthwaite.bsky.social (Psych) @chopresearch.bsky.social www.nature.com/articles/s41...
February 9, 2026 at 3:41 PM
New research out in @nature.com delineates two replicable axes of human white matter development ft. @audreycluo.bsky.social & @ted-satterthwaite.bsky.social (Psych) @chopresearch.bsky.social www.nature.com/articles/s41...
Reposted by Corey Horien
I wrote an perspectives piece relevant to the structural atlasing endeavors. Structural atlases are not the end of the story. This perspective calls for models that take into account the flexible functional organization within this fixed architecture.
www.frontiersin.org/journals/neu...
www.frontiersin.org/journals/neu...
Frontiers | Structure–function relationships across scales: implications for atlases
Neuroscience aims to understand how the structural and functional organization of the brain relates to behavior. Structural studies at the cellular level est...
www.frontiersin.org
February 9, 2026 at 1:53 PM
I wrote an perspectives piece relevant to the structural atlasing endeavors. Structural atlases are not the end of the story. This perspective calls for models that take into account the flexible functional organization within this fixed architecture.
www.frontiersin.org/journals/neu...
www.frontiersin.org/journals/neu...
Reposted by Corey Horien
Using 7T fMRI, our team found a representation of the probability of the next event in human dlPFC —and it’s highly non-monotonic.
Confidence signals, in contrast, were mostly monotonic.
doi.org/10.1038/s414...
🧠🟦🧠🤖
Confidence signals, in contrast, were mostly monotonic.
doi.org/10.1038/s414...
🧠🟦🧠🤖
February 7, 2026 at 2:57 PM
Using 7T fMRI, our team found a representation of the probability of the next event in human dlPFC —and it’s highly non-monotonic.
Confidence signals, in contrast, were mostly monotonic.
doi.org/10.1038/s414...
🧠🟦🧠🤖
Confidence signals, in contrast, were mostly monotonic.
doi.org/10.1038/s414...
🧠🟦🧠🤖
Reposted by Corey Horien
ICE told nurses this Minneapolis man “purposefully ran headfirst into a brick wall.”
What actually happened is that they pulled him from a car, beat him so viciously with a steel baton that he had 8 skull fractures, 5 life-threatening brain hemorrhages, and couldn’t remember he had a daughter.
What actually happened is that they pulled him from a car, beat him so viciously with a steel baton that he had 8 skull fractures, 5 life-threatening brain hemorrhages, and couldn’t remember he had a daughter.
February 7, 2026 at 5:54 PM
ICE told nurses this Minneapolis man “purposefully ran headfirst into a brick wall.”
What actually happened is that they pulled him from a car, beat him so viciously with a steel baton that he had 8 skull fractures, 5 life-threatening brain hemorrhages, and couldn’t remember he had a daughter.
What actually happened is that they pulled him from a car, beat him so viciously with a steel baton that he had 8 skull fractures, 5 life-threatening brain hemorrhages, and couldn’t remember he had a daughter.
Reposted by Corey Horien
“Renee Goodman [sic], Alex Pretti – there are no words,” DeLauro said.
“You said there were no words after the murder of those two individuals,” said Rev. Jack Perkins Davidson. “I think the words are ‘Abolish ICE.’”
www.ctpublic.org/news/2026-02...
“You said there were no words after the murder of those two individuals,” said Rev. Jack Perkins Davidson. “I think the words are ‘Abolish ICE.’”
www.ctpublic.org/news/2026-02...
DeLauro to pressing clergy: 'I will not vote to abolish ICE'
The Connecticut U.S. representative found herself at odds with faith leaders.
www.ctpublic.org
February 6, 2026 at 11:28 PM
“Renee Goodman [sic], Alex Pretti – there are no words,” DeLauro said.
“You said there were no words after the murder of those two individuals,” said Rev. Jack Perkins Davidson. “I think the words are ‘Abolish ICE.’”
www.ctpublic.org/news/2026-02...
“You said there were no words after the murder of those two individuals,” said Rev. Jack Perkins Davidson. “I think the words are ‘Abolish ICE.’”
www.ctpublic.org/news/2026-02...
Reposted by Corey Horien
New paper in Imaging Neuroscience by Daniel Haenelt, Robert Trampel, et al:
Decoding of columnar-level organization across cortical depth using BOLD- and CBV-fMRI at 7 T
doi.org/10.1162/IMAG...
Decoding of columnar-level organization across cortical depth using BOLD- and CBV-fMRI at 7 T
doi.org/10.1162/IMAG...
February 7, 2026 at 8:17 AM
New paper in Imaging Neuroscience by Daniel Haenelt, Robert Trampel, et al:
Decoding of columnar-level organization across cortical depth using BOLD- and CBV-fMRI at 7 T
doi.org/10.1162/IMAG...
Decoding of columnar-level organization across cortical depth using BOLD- and CBV-fMRI at 7 T
doi.org/10.1162/IMAG...
Reposted by Corey Horien
By the way, for those of you not in MN: Homan’s strategy was to withdraw some agents, so it felt like we were in the denouement of the crisis, and then escalate hard against observers. They’re being incredibly aggressive with observers now. National media may not want to check out just yet
February 7, 2026 at 3:38 AM
By the way, for those of you not in MN: Homan’s strategy was to withdraw some agents, so it felt like we were in the denouement of the crisis, and then escalate hard against observers. They’re being incredibly aggressive with observers now. National media may not want to check out just yet
Reposted by Corey Horien
This is a beautiful case of how real science happens & serious scientists work. Kudos to both set of authors: “This has been a humbling experience, but one that speaks to the self-correcting nature of the scientific endeavor.” www.science.org/doi/10.1126/...
RETRACTED: Integrative phylogenomics positions sponges at the root of the animal tree
Determining whether sponges or ctenophores root the animal tree has important implications for understanding early animal evolution. Here, we examined support for these competing hypotheses by constru...
www.science.org
February 6, 2026 at 7:35 PM
This is a beautiful case of how real science happens & serious scientists work. Kudos to both set of authors: “This has been a humbling experience, but one that speaks to the self-correcting nature of the scientific endeavor.” www.science.org/doi/10.1126/...
Reposted by Corey Horien
The big questions facing psychedelic science:
1. What’s the biology of psychedelic experiences?
2. Is the experience necessary for clinical benefit?
3. How do we solve expectancy+unblinding in trials?
We synthesize what we know and the big Qs in a Nature Med Review:
nature.com/articles/s41...
1. What’s the biology of psychedelic experiences?
2. Is the experience necessary for clinical benefit?
3. How do we solve expectancy+unblinding in trials?
We synthesize what we know and the big Qs in a Nature Med Review:
nature.com/articles/s41...
The science of psychedelic medicine - Nature Medicine
This Review outlines the science behind psychedelic medicine and integrates mechanistic knowledge with clinical evidence across neuropsychiatric indications, highlighting challenges, controversies and...
nature.com
February 6, 2026 at 4:02 PM
The big questions facing psychedelic science:
1. What’s the biology of psychedelic experiences?
2. Is the experience necessary for clinical benefit?
3. How do we solve expectancy+unblinding in trials?
We synthesize what we know and the big Qs in a Nature Med Review:
nature.com/articles/s41...
1. What’s the biology of psychedelic experiences?
2. Is the experience necessary for clinical benefit?
3. How do we solve expectancy+unblinding in trials?
We synthesize what we know and the big Qs in a Nature Med Review:
nature.com/articles/s41...
Reposted by Corey Horien
I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 5, 2026 at 7:24 PM
I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Corey Horien
The Minneapolis City Council allocated $1 million to help residents pay rent as part of an effort to help immigrants who have lost income amid the federal immigration crackdown.
Minneapolis City Council votes to spend $1 million to help people pay rent amid immigration surge
Despite concern about the city’s finances, the council voted to dig into its cash balance to help renters as eviction filings spike statewide.
www.startribune.com
February 6, 2026 at 12:07 AM
The Minneapolis City Council allocated $1 million to help residents pay rent as part of an effort to help immigrants who have lost income amid the federal immigration crackdown.
Reposted by Corey Horien
Ever wondered how the Dalmatian Dog effect works?
The human brain can quickly learn from a single experience and generalize it to related experiences — an impressive feat so far not matched by AI.
Our new paper in @natcomms.nature.com reveals how this works.
www.nature.com/articles/s41...
The human brain can quickly learn from a single experience and generalize it to related experiences — an impressive feat so far not matched by AI.
Our new paper in @natcomms.nature.com reveals how this works.
www.nature.com/articles/s41...
February 4, 2026 at 5:01 PM
Ever wondered how the Dalmatian Dog effect works?
The human brain can quickly learn from a single experience and generalize it to related experiences — an impressive feat so far not matched by AI.
Our new paper in @natcomms.nature.com reveals how this works.
www.nature.com/articles/s41...
The human brain can quickly learn from a single experience and generalize it to related experiences — an impressive feat so far not matched by AI.
Our new paper in @natcomms.nature.com reveals how this works.
www.nature.com/articles/s41...
Reposted by Corey Horien
New paper in Imaging Neuroscience by Ayumu Yamashita, Okito Yamashita, et al:
Extraction of robust functional connectivity patterns across psychiatric disorders using principal component analysis-based feature selection
doi.org/10.1162/IMAG...
Extraction of robust functional connectivity patterns across psychiatric disorders using principal component analysis-based feature selection
doi.org/10.1162/IMAG...
February 5, 2026 at 7:48 AM
New paper in Imaging Neuroscience by Ayumu Yamashita, Okito Yamashita, et al:
Extraction of robust functional connectivity patterns across psychiatric disorders using principal component analysis-based feature selection
doi.org/10.1162/IMAG...
Extraction of robust functional connectivity patterns across psychiatric disorders using principal component analysis-based feature selection
doi.org/10.1162/IMAG...
Reposted by Corey Horien
Posting more from the @sanders.senate.gov HELP committee report, this time on the clinical center, which has been devastated. www.sanders.senate.gov/wp-content/u...
February 5, 2026 at 5:03 AM
Posting more from the @sanders.senate.gov HELP committee report, this time on the clinical center, which has been devastated. www.sanders.senate.gov/wp-content/u...
Reposted by Corey Horien
It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalizing SCAN connectivity represents a shared mechanism across diverse effective therapies.
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
February 5, 2026 at 12:35 AM
It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalizing SCAN connectivity represents a shared mechanism across diverse effective therapies.
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
Reposted by Corey Horien
Social “envirotyping” the ABCD study contextualizes dissociable brain organization and diverging outcomes
New paper from former BNBL-er and current postdoc at Northeastern University, London @h-merritt.bsky.social
doi.org/10.1093/scan...
New paper from former BNBL-er and current postdoc at Northeastern University, London @h-merritt.bsky.social
doi.org/10.1093/scan...
Social “envirotyping” the ABCD study contextualizes dissociable brain organization and diverging outcomes
Abstract. The environment, especially social features, plays a key role in shaping the development of the brain, notably during adolescence. To better unde
doi.org
February 3, 2026 at 6:21 PM
Social “envirotyping” the ABCD study contextualizes dissociable brain organization and diverging outcomes
New paper from former BNBL-er and current postdoc at Northeastern University, London @h-merritt.bsky.social
doi.org/10.1093/scan...
New paper from former BNBL-er and current postdoc at Northeastern University, London @h-merritt.bsky.social
doi.org/10.1093/scan...
Reposted by Corey Horien
Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign.
(1) $48.7 billion for NIH
(2) Full IDC recovery
(3) No more multi-year funding
(4) No NIH reorganization, maintaining the current IC structure.
(1) $48.7 billion for NIH
(2) Full IDC recovery
(3) No more multi-year funding
(4) No NIH reorganization, maintaining the current IC structure.
February 3, 2026 at 7:48 PM
Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign.
(1) $48.7 billion for NIH
(2) Full IDC recovery
(3) No more multi-year funding
(4) No NIH reorganization, maintaining the current IC structure.
(1) $48.7 billion for NIH
(2) Full IDC recovery
(3) No more multi-year funding
(4) No NIH reorganization, maintaining the current IC structure.
Reposted by Corey Horien
Excited to share a new preprint, led by the inimitable @colleenhughes.bsky.social!
Individualized Mapping of Functional Brain Networks in Older Adulthood
www.biorxiv.org/content/10.6...
A short 🧵 1/
Individualized Mapping of Functional Brain Networks in Older Adulthood
www.biorxiv.org/content/10.6...
A short 🧵 1/
www.biorxiv.org
February 3, 2026 at 7:04 PM
Excited to share a new preprint, led by the inimitable @colleenhughes.bsky.social!
Individualized Mapping of Functional Brain Networks in Older Adulthood
www.biorxiv.org/content/10.6...
A short 🧵 1/
Individualized Mapping of Functional Brain Networks in Older Adulthood
www.biorxiv.org/content/10.6...
A short 🧵 1/
Reposted by Corey Horien
happening this morning in Minneapolis -- ICE agents drawing guns on observers. I reiterate again that it is only a matter of time before DHS kills more innocent people in Minnesota. Congress needs to shut this shit down right now.
February 3, 2026 at 4:19 PM
happening this morning in Minneapolis -- ICE agents drawing guns on observers. I reiterate again that it is only a matter of time before DHS kills more innocent people in Minnesota. Congress needs to shut this shit down right now.
Reposted by Corey Horien
Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia across species
Convergent transcriptomic and connectomic controllers of information integration and its anaesthetic breakdown across mammalian brains - Nature Human Behaviour
Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia in humans, macaques, marmosets and mice.
dlvr.it
January 29, 2026 at 2:55 PM
Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia across species
Reposted by Corey Horien
The 2024 US societal cost of #Schizophrenia was $366.8 billion, with unpaid caregiving, lost wages, and reduced quality of life accounting for over 75% of total costs.
ja.ma/3ZI3YBB
ja.ma/3ZI3YBB
February 2, 2026 at 3:00 PM
The 2024 US societal cost of #Schizophrenia was $366.8 billion, with unpaid caregiving, lost wages, and reduced quality of life accounting for over 75% of total costs.
ja.ma/3ZI3YBB
ja.ma/3ZI3YBB
Reposted by Corey Horien
👀
Did you miss me? Making the most of digital phenotyping data by imputing missingness with point process models | medRxiv www.medrxiv.org/content/10.1...
Did you miss me? Making the most of digital phenotyping data by imputing missingness with point process models | medRxiv www.medrxiv.org/content/10.1...
February 1, 2026 at 10:13 PM
👀
Did you miss me? Making the most of digital phenotyping data by imputing missingness with point process models | medRxiv www.medrxiv.org/content/10.1...
Did you miss me? Making the most of digital phenotyping data by imputing missingness with point process models | medRxiv www.medrxiv.org/content/10.1...