Corey Horien
@coreyhorien.bsky.social
Research track resident in psychiatry at UPenn | PennLINC
Neuroimaging, development, precision psychiatry
Neuroimaging, development, precision psychiatry
Reposted by Corey Horien
Very well done story on 60 Minutes about the harms of grant terminations and freezes at Harvard with Joan Brugge, Don Engbar, David Liu, and a very compelling young cancer patient, now cured with Liu's technology.
Transcript and video here
www.cbsnews.com/news/researc...
Transcript and video here
www.cbsnews.com/news/researc...
Battle between Trump and universities hurting scientific research in need of federal funding
Federal research funding to universities has fueled breakthroughs for years. The White House is pressuring universities to align with the president's political agenda, or risk losing their funding.
www.cbsnews.com
November 10, 2025 at 1:03 AM
Very well done story on 60 Minutes about the harms of grant terminations and freezes at Harvard with Joan Brugge, Don Engbar, David Liu, and a very compelling young cancer patient, now cured with Liu's technology.
Transcript and video here
www.cbsnews.com/news/researc...
Transcript and video here
www.cbsnews.com/news/researc...
Reposted by Corey Horien
Bullies gain power when their misconduct succeeds in causing righteous people to yield in the face of wrongdoing. That’s why voting for Trump's continuing resolution - without any protection against his health care cuts or his growing illegality - is a mistake.
I voted NO.
I voted NO.
November 10, 2025 at 2:19 AM
Bullies gain power when their misconduct succeeds in causing righteous people to yield in the face of wrongdoing. That’s why voting for Trump's continuing resolution - without any protection against his health care cuts or his growing illegality - is a mistake.
I voted NO.
I voted NO.
Reposted by Corey Horien
Congratulations to Erica Baller (Psychiatry), recipient of the Leonard Berwick Memorial Teaching Award! Learn more Dr. Baller & her research interests here➡️ ericaballer.wixsite.com/baller-lab #PSOMAOE
November 5, 2025 at 6:11 PM
Congratulations to Erica Baller (Psychiatry), recipient of the Leonard Berwick Memorial Teaching Award! Learn more Dr. Baller & her research interests here➡️ ericaballer.wixsite.com/baller-lab #PSOMAOE
Reposted by Corey Horien
First Asian American mayor of Cincinnati!
Lots of firsts tonight.
First Muslim woman as Lt. Gov. of VA
First woman Governor of VA
People are voting for the America they want.
Powerfully.
And it MEANS something.
They’re voting against what they DON’T want.
Take heart!
Lots of firsts tonight.
First Muslim woman as Lt. Gov. of VA
First woman Governor of VA
People are voting for the America they want.
Powerfully.
And it MEANS something.
They’re voting against what they DON’T want.
Take heart!
Pureval got 81% of the votes over Vance’s brother! First Asian-American mayor of Cincinnati!
November 5, 2025 at 1:54 AM
First Asian American mayor of Cincinnati!
Lots of firsts tonight.
First Muslim woman as Lt. Gov. of VA
First woman Governor of VA
People are voting for the America they want.
Powerfully.
And it MEANS something.
They’re voting against what they DON’T want.
Take heart!
Lots of firsts tonight.
First Muslim woman as Lt. Gov. of VA
First woman Governor of VA
People are voting for the America they want.
Powerfully.
And it MEANS something.
They’re voting against what they DON’T want.
Take heart!
Reposted by Corey Horien
I think a thing we'll learn tonight is that people fucking hate what is going on and they will straight ticket vote against anyone involved in starving people while pillaging the country and kidnapping their neighbors. I don't think it matters at all who that person is.
November 5, 2025 at 12:44 AM
I think a thing we'll learn tonight is that people fucking hate what is going on and they will straight ticket vote against anyone involved in starving people while pillaging the country and kidnapping their neighbors. I don't think it matters at all who that person is.
Reposted by Corey Horien
Preprint is now published: doi.org/10.1002/hbm....
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
November 4, 2025 at 12:32 AM
Preprint is now published: doi.org/10.1002/hbm....
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Reposted by Corey Horien
New from @haleyrwang.bsky.social: Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis - Biological Psychiatry www.biologicalpsychiatryjournal.com/article/S000...
Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis
Early psychosis (EP) is characterized by neurobiological changes, including alterations
in resting-state functional connectivity (RSFC). We now understand that symptoms and
neural changes may overlap ...
www.biologicalpsychiatryjournal.com
November 3, 2025 at 7:29 PM
New from @haleyrwang.bsky.social: Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis - Biological Psychiatry www.biologicalpsychiatryjournal.com/article/S000...
Reposted by Corey Horien
Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government
go.nature.com/47hn0n5
go.nature.com/47hn0n5
7 basic science discoveries that changed the world
Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.
go.nature.com
November 1, 2025 at 5:39 PM
Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government
go.nature.com/47hn0n5
go.nature.com/47hn0n5
Reposted by Corey Horien
This is precisely what the kleptocrats wanted all along.
Because whatever profits they could reap from future investments in research won't outweigh the costs of allowing the public to be informed.
Because whatever profits they could reap from future investments in research won't outweigh the costs of allowing the public to be informed.
A Nature poll found that 75% of U.S. researchers are considering leaving the country.
Guyz, even the *historians* are leaving or contemplating / likely to go. Including, at least 3 historians that I know of in my subfield. 😢
Guyz, even the *historians* are leaving or contemplating / likely to go. Including, at least 3 historians that I know of in my subfield. 😢
Top researchers consider leaving U.S. amid funding cuts: 'The science world is ending'
A poll from the journal Nature found that 75% of researchers in the U.S. are considering leaving the country. That includes a man who’s been dubbed the "Mozart of Math." Stephanie Sy examines what’s b...
www.pbs.org
October 31, 2025 at 8:33 PM
This is precisely what the kleptocrats wanted all along.
Because whatever profits they could reap from future investments in research won't outweigh the costs of allowing the public to be informed.
Because whatever profits they could reap from future investments in research won't outweigh the costs of allowing the public to be informed.
Reposted by Corey Horien
Excited to see this one in print! Emerging methods for brain-based predictions in psychiatry. Led by @diawang.bsky.social and @yiplab.bsky.social w/ @bttyeo.bsky.social
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
October 30, 2025 at 9:16 PM
Excited to see this one in print! Emerging methods for brain-based predictions in psychiatry. Led by @diawang.bsky.social and @yiplab.bsky.social w/ @bttyeo.bsky.social
Reposted by Corey Horien
The best share of one's research results I have seen inna long time. Congratulations, Francesca!
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice
Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...
www.biorxiv.org
October 31, 2025 at 8:32 PM
The best share of one's research results I have seen inna long time. Congratulations, Francesca!
Reposted by Corey Horien
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
October 30, 2025 at 3:21 PM
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
Reposted by Corey Horien
In a world first, a bespoke gene-editing therapy benefitted one child. Now reseachers plan to launch a clinical trial of the approach
go.nature.com/3JctjPL
go.nature.com/3JctjPL
Personalized gene editing helped one baby: can it be rolled out widely?
In a world first, a bespoke gene-editing therapy benefitted one child. Now reseachers plan to launch a clinical trial of the approach.
go.nature.com
October 31, 2025 at 4:57 PM
In a world first, a bespoke gene-editing therapy benefitted one child. Now reseachers plan to launch a clinical trial of the approach
go.nature.com/3JctjPL
go.nature.com/3JctjPL
Take a look at our paper! Led by @francimandi.bsky.social in the Lake lab: "Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice" !!!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice
Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...
www.biorxiv.org
October 31, 2025 at 4:39 PM
Take a look at our paper! Led by @francimandi.bsky.social in the Lake lab: "Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice" !!!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Corey Horien
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice
Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...
www.biorxiv.org
October 31, 2025 at 1:52 PM
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Reposted by Corey Horien
Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain.
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
Top researchers consider leaving U.S. amid funding cuts: 'The science world is ending'
YouTube video by PBS NewsHour
www.youtube.com
October 30, 2025 at 11:36 AM
Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain.
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
Reposted by Corey Horien
I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...
I’m an award-winning mathematician. Trump just cut my funding.
The “Mozart of Math” tried to stay out of politics. Then it came for his research.
newsletter.ofthebrave.org
August 18, 2025 at 3:45 PM
I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...
Reposted by Corey Horien
😅
thrilled!! but speaking after @monicarosenb.bsky.social ??? that's too tough to follow
October 30, 2025 at 1:17 AM
😅
Reposted by Corey Horien
Psychedelics disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help.
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry
The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help…
www.thetransmitter.org
October 29, 2025 at 6:05 PM
Psychedelics disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help.
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
Reposted by Corey Horien
Funders must recognise that great discoveries often come from studies that seeks to advance knowledge for its own sake
go.nature.com/47zrzYZ
go.nature.com/47zrzYZ
From MRI to Ozempic: breakthroughs that show why fundamental research must be protected
In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.
go.nature.com
October 29, 2025 at 12:11 PM
Funders must recognise that great discoveries often come from studies that seeks to advance knowledge for its own sake
go.nature.com/47zrzYZ
go.nature.com/47zrzYZ
Reposted by Corey Horien
Acetaminophen (Tylenol) in pregnancy does not increase the risk of autism @jama.com @ki.se
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability
This nationwide cohort study with sibling control analysis examines the association of acetaminophen use during pregnancy with children’s risk of autism, ADHD, and intellectual disability.
jamanetwork.com
October 28, 2025 at 2:53 PM
Acetaminophen (Tylenol) in pregnancy does not increase the risk of autism @jama.com @ki.se
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Corey Horien
American parents, please ignore Trump’s recent reiteration of nonsense about Tylenol and vaccines, as well as anything the man ever says about the health of your children. Please talk with your medical professionals.
October 27, 2025 at 9:37 PM
American parents, please ignore Trump’s recent reiteration of nonsense about Tylenol and vaccines, as well as anything the man ever says about the health of your children. Please talk with your medical professionals.
Reposted by Corey Horien
New Paper in Nature Communications!
We present exciting work on applying transfer learning on minimally invasive recordings to build scalable speech BCI for a more heterogeneous population. #iEEG #neuroskyence
Check it out : www.nature.com/articles/s41...
We present exciting work on applying transfer learning on minimally invasive recordings to build scalable speech BCI for a more heterogeneous population. #iEEG #neuroskyence
Check it out : www.nature.com/articles/s41...
Transfer learning via distributed brain recordings enables reliable speech decoding - Nature Communications
Speech brain-computer interfaces face challenges scaling across individuals with different brain organization. Using minimally invasive recordings from 25 patients, the authors developed transfer learning methods that enable robust speech decoding even with incomplete brain coverage.
www.nature.com
October 2, 2025 at 3:02 PM
New Paper in Nature Communications!
We present exciting work on applying transfer learning on minimally invasive recordings to build scalable speech BCI for a more heterogeneous population. #iEEG #neuroskyence
Check it out : www.nature.com/articles/s41...
We present exciting work on applying transfer learning on minimally invasive recordings to build scalable speech BCI for a more heterogeneous population. #iEEG #neuroskyence
Check it out : www.nature.com/articles/s41...
Reposted by Corey Horien
Breaking: The Department of Justice announced it will "monitor polling sites in six jurisdictions [in New Jersey and California] ahead of the upcoming November 4, 2025, general election to ensure transparency, ballot security, and compliance with federal law." www.justice.gov/opa/pr/justi...
Justice Department to Monitor Polling Sites in California, New Jersey
WASHINGTON – Today, the Department of Justice announced that it will monitor polling sites in six jurisdictions ahead of the upcoming November 4, 2025, general election to ensure transparency, ballot ...
www.justice.gov
October 24, 2025 at 3:20 PM
Breaking: The Department of Justice announced it will "monitor polling sites in six jurisdictions [in New Jersey and California] ahead of the upcoming November 4, 2025, general election to ensure transparency, ballot security, and compliance with federal law." www.justice.gov/opa/pr/justi...
Reposted by Corey Horien
New preprint ↙️
Using 2 independent 7T fMRI datasets (HCP & our PNI dataset 🧲 💅 ), we found that intersubject synchronization 👯 during movies aligns closely with cortical gradients 🌈, especially along the visual-to-transmodal axis
by Meaghan Smith & a terrific team ↙️
doi.org/10.1101/2025...
Using 2 independent 7T fMRI datasets (HCP & our PNI dataset 🧲 💅 ), we found that intersubject synchronization 👯 during movies aligns closely with cortical gradients 🌈, especially along the visual-to-transmodal axis
by Meaghan Smith & a terrific team ↙️
doi.org/10.1101/2025...
October 22, 2025 at 2:43 PM
New preprint ↙️
Using 2 independent 7T fMRI datasets (HCP & our PNI dataset 🧲 💅 ), we found that intersubject synchronization 👯 during movies aligns closely with cortical gradients 🌈, especially along the visual-to-transmodal axis
by Meaghan Smith & a terrific team ↙️
doi.org/10.1101/2025...
Using 2 independent 7T fMRI datasets (HCP & our PNI dataset 🧲 💅 ), we found that intersubject synchronization 👯 during movies aligns closely with cortical gradients 🌈, especially along the visual-to-transmodal axis
by Meaghan Smith & a terrific team ↙️
doi.org/10.1101/2025...