Sina Mansour L.
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sinamansourl.bsky.social
Sina Mansour L.
@sinamansourl.bsky.social
Postdoctoral Research Fellow at the National University of Singapore (NUS)
Network Science enthusiast, in pursuit of computational neuroscience
https://sina-mansour.github.io/
Pinned
1/ Excited to share our latest preprint! 🚀 We introduce Spectral Normative Modeling (SNM)—a novel approach leveraging graph spectral methods to advance brain charting towards personalized precision medicine.

🔗 www.medrxiv.org/content/10.1...
Spectral normative modeling of brain structure
Normative modeling in neuroscience aims to characterize interindividual variation in brain phenotypes and thus establish reference ranges, or brain charts, against which individual brains can be compa...
www.medrxiv.org
Reposted by Sina Mansour L.
Can brain training improve #meditation? 🧘‍♂️

New study by @saampras.bsky.social featuring AddPro's @vale-addiction.bsky.social suggests that #neurofeedback can boost awareness + reduce emotional distress during meditation in beginners!

🔗 link.springer.com/article/10.1...

Congrats to all authors!
September 29, 2025 at 1:18 AM
Reposted by Sina Mansour L.
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
🧠 #OHBM2025 is fast approaching, with a stellar educational session from @ohbmossig.bsky.social & @ohbmenvironment.bsky.social

I'll be presenting a semi-hands-on course on reproducible research workflows, from code to visualization.

📖 Slides are now online:
sina-mansour.github.io/ohbm2025-rep...
From Code to Visualization: Reproducible Pipelines for Neuroimaging Research
Presentation Slides for OHBM 2025 Educational Session
sina-mansour.github.io
June 13, 2025 at 9:44 AM
Can deep learning help us solve dynamical systems problems, particularly those used in neural mass models? Check out this preprint to read about the perks...
While the world burns, we cook up a new preprint! doi.org/10.1101/2025...

Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
April 20, 2025 at 12:29 PM
Reposted by Sina Mansour L.
Join us Mon 3/10 for a roundtable discussion addressing best practices and emerging opportunities in human brain imaging and how they can advance the study of women’s brain health.
February 27, 2025 at 7:29 PM
Reposted by Sina Mansour L.
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...

Funded by National Institute of Mental Health (NIMH)
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health
Major mental disorders are increasingly understood as disorders of brain development. Large and heterogeneous samples are required to define generalizable links between brain development and psychopat...
doi.org
February 27, 2025 at 8:57 PM
Reposted by Sina Mansour L.
New paper‼️ Interested in the protective impacts of parenthood on brain dynamics? 👨‍👩‍👦‍👦🧠 Read Edwina Orchard & @sidchop.bsky.social's new paper, out now in PNAS @pnas.org !

With collaborators L. Ooi, P. Chen, L. An @bttyeo.bsky.social, and more!

🔗https://tinyurl.com/parentalbrain
February 25, 2025 at 7:15 PM
Reposted by Sina Mansour L.
Congrats to Winnie Orchard & @sidchop.bsky.social on their new #ParentalBrain paper, now out in PNAS! They find evidence for the neuroprotective effect of parenthood for women AND men! 👩‍🍼👨‍🍼🧠 It's lovely work, and I'm proud to have played a tiny role in it. Read it here 👇 #neuroskyence #neuroimaging
New paper‼️ Interested in the protective impacts of parenthood on brain dynamics? 👨‍👩‍👦‍👦🧠 Read Edwina Orchard & @sidchop.bsky.social's new paper, out now in PNAS @pnas.org !

With collaborators L. Ooi, P. Chen, L. An @bttyeo.bsky.social, and more!

🔗https://tinyurl.com/parentalbrain
February 26, 2025 at 11:29 PM
Reposted by Sina Mansour L.
SOBP BrainHack is officially open for registration!

The hackathon will be held April 22-23 at Sick Kids Toronto. Beginners and experienced hackers welcome!

Website and registration: www.repronim.org/SOBPHack-042...
February 25, 2025 at 1:25 AM
Reposted by Sina Mansour L.
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | www.biorxiv.org/content/10.1...
a man with glasses is sitting on a couch and saying pretty pretty pretty good .
ALT: a man with glasses is sitting on a couch and saying pretty pretty pretty good .
media.tenor.com
February 27, 2025 at 1:40 AM
Reposted by Sina Mansour L.
If we could record all neurons we still would not know how they communicate: medium.com/@kording/628...
Would recording all neurons reveal their interactions?
For years, I was captivated by the idea that if we could record the activity of every neuron in the brain, we’d eventually crack the code…
medium.com
February 26, 2025 at 7:36 PM
Reposted by Sina Mansour L.
Do you work on surface MRI such as HCP data? Our paper is finally out in Imaging Neuroscience, showing biases in surface fMRI. The revised ms has many new insights!
TLDR: Vertices are much closer to each other in sulci, resulting in (fake) high spatial autocorrelation. (1/5)
February 25, 2025 at 12:36 AM
Had a fantastic time presenting our novel eigenmode-driven normative models at the ISMRM Diffusion Workshop! 🧠📊

Check out our preprint here: www.medrxiv.org/content/10.1...
February 23, 2025 at 8:25 AM
Reposted by Sina Mansour L.
Video tutorials on how to use MSM cortical surface registration: classic, groupwise and anatomical
youtu.be/rQQx0k1Sgdc?...
Multimodal Surface Matching (MSM) tutorials
YouTube video by Emma Robinson
youtu.be
February 16, 2025 at 9:20 PM
Great talk by Simona Schiavi at the ISMRM workshop on 40 years of diffusion! Interesting to see the DK atlas as the top choice for mapping connectomes—though, as expected, a diverse range of opinions. No single right answer!

@ismrm.bsky.social
February 16, 2025 at 8:35 AM
Reposted by Sina Mansour L.
So much research focusses on using brain connectivity to predict an individual's cognition, IQ, disease status, etc.

BUT what about the inverse problem?

Can personal data be used to build an individual's whole connectome?

YES - with AI:

www.biorxiv.org/content/10.1...
February 15, 2025 at 12:45 AM
Useful read to sharpen your "Defence against the dark charts" 🪄
Dishonest charts are coming from all directions, and they're only going to hit harder. Unless we push back. So, an interactive guide: Defense Against Dishonest Charts flowingdata.com/projects/dis...
Defense Against Dishonest Charts
This is a guide to protect ourselves and to preserve what is good about turning data into visual things.
flowingdata.com
February 14, 2025 at 5:12 AM
Reposted by Sina Mansour L.
Connectome architecture favours within-module diffusion and between-module routing.

Really cool multi-species work from Caio Seguin on module-defined communication policies in connectomes!

www.biorxiv.org/content/10.1...
February 12, 2025 at 4:31 PM
Reposted by Sina Mansour L.
Caio is having a good day. Another preprint on which he's first author -- this time, describing pathways through the connectome for indirectly stimulating subgenual cingulate cortex in the context of depression.

Neuroanatomical pathways of TMS therapy for depression

www.medrxiv.org/content/10.1...
February 12, 2025 at 7:32 PM
Reposted by Sina Mansour L.
TMS is delivered to the DLPFC in depression to modulate SGC activity

But axons linking DLPFC and SGC are absent.

How then does TMS stimulation delivered to the DLPFC modulate SGC activity?

Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
Caio is having a good day. Another preprint on which he's first author -- this time, describing pathways through the connectome for indirectly stimulating subgenual cingulate cortex in the context of depression.

Neuroanatomical pathways of TMS therapy for depression

www.medrxiv.org/content/10.1...
February 13, 2025 at 4:06 AM
🚀 Explore Spectral Normative Modeling in action!

We’ve built an interactive visualization showcasing high-resolution normative reference ranges generated via SNM.

🔗 Try it here: sina-mansour.github.io/normative_br...
February 13, 2025 at 5:03 AM
💥 special issue on open datasets: deadline extended 💥
🚨 Deadline Extended 🚨

🗓️ Good news! The submission deadline for the Special Issue on Open Datasets has been extended to April 30th, 2025.

Don't miss this opportunity to contribute to critical discussions on data governance, ethics, infrastructure, and more!

🔗 Learn more at: tinyurl.com/5n7xruwz
February 8, 2025 at 7:32 AM
1/ Excited to share our latest preprint! 🚀 We introduce Spectral Normative Modeling (SNM)—a novel approach leveraging graph spectral methods to advance brain charting towards personalized precision medicine.

🔗 www.medrxiv.org/content/10.1...
Spectral normative modeling of brain structure
Normative modeling in neuroscience aims to characterize interindividual variation in brain phenotypes and thus establish reference ranges, or brain charts, against which individual brains can be compa...
www.medrxiv.org
February 6, 2025 at 5:17 AM
Reposted by Sina Mansour L.
SPM goes Python for its 30 year anniversary! Great news for #neuroimaging! 👍
Happy 30th birthday year to SPM!! 🎈🍰

To get the party started, we are delighted to announce SPM 25.01, a major new version of the open-source neuroimaging software.

Read the preprint to discover what's new arxiv.org/pdf/2501.12081 and download SPM for free from Github github.com/spm/spm/rele...
arxiv.org
January 24, 2025 at 11:12 PM
Reposted by Sina Mansour L.
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...

The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
January 24, 2025 at 12:02 AM