american-citizen25.bsky.social
@american-citizen25.bsky.social
Reposted
A subset of patients with NSCLC that have a specific ALK gene fusion in their tumors may need to target a third pathway for treatments to be effective.

Learn more in #ScienceSignaling: https://scim.ag/44GnjWP
Cancer-associated fibroblasts confer ALK inhibitor resistance in EML4-ALK–driven lung cancer by concurrent integrin and MET signaling
Secretory and cell-contact signaling from tumor stromal fibroblasts drive drug resistance in lung cancer.
scim.ag
December 26, 2025 at 3:51 PM
December 26, 2025 at 5:10 AM
December 26, 2025 at 5:09 AM
December 26, 2025 at 5:09 AM
December 26, 2025 at 5:08 AM
December 26, 2025 at 5:08 AM
December 26, 2025 at 5:08 AM
Reposted
The billionaire said new grads can help small and medium businesses adopt AI agents, something big companies don't need them for.
Mark Cuban said there's a compelling reason for new grads to join small businesses instead of big companies
The billionaire said new grads can help small and medium businesses adopt AI agents, something big companies don't need them for.
www.businessinsider.com
December 26, 2025 at 5:06 AM
Still believe us blowing up about 100 people in small boats about 2000 miles from the US, close to OIL RICH Venezuela is about drugs??
Is stealing two OIL tankers from Venezuela about drugs too??
December 26, 2025 at 1:28 AM
Trump is now sanctioning European officials for fining Twitter over disinformation and violations of EU law

I’d simply say okay—we’ll drop the fines once you lift the sanctions

Once the sanctions are gone, block the platform entirely

Trump said nothing when Russia/China banned Twitter
-D Knight
December 26, 2025 at 1:00 AM
Reposted
If only we had cleaned the air and not minimized living with infectious disease. 🤷

www.ctvnews.ca/health/artic...
Expert calls 2025 flu ‘more infectious,’ as provinces see rise in infected children
Canada’s flu season is off to an unusually early and intense start this year, with experts warning that a more infectious strain is driving higher case counts across the country.
www.ctvnews.ca
December 25, 2025 at 9:23 PM
substack.com/@kieratkinso...
Canadian Charter of Rights
Kier Atkinson 🇨🇦 (@kieratkinson)
substack.com
December 25, 2025 at 8:39 PM
Reposted
Trump is manipulating national security to stop energy projects he doesn't like, while ignoring and censoring real environmental security threats.
That's corrupt and dangerous.
thebulletin.org/2025/12/trum...
Trump is manipulating national security to stop energy projects he doesn’t like
On Monday, December 22, the Trump Administration announced it was pausing five major offshore wind energy projects, citing “national security risks.”
thebulletin.org
December 25, 2025 at 8:11 PM
americancitizen2025.substack.com/p/letter-1-t...
Letter to protect your retirements.
At the bottom is a link for a second letter to try to be able to afford your healthcare next year. Right now is when they are planning for healthcare in 2027
Letter #1 to send to your companies HR dept asking them to protect your retirement funds against an economic crash. Letter #2 will be for helping you to be able to afford healthcare insurance in 2027
Dear company officials,
americancitizen2025.substack.com
December 25, 2025 at 8:09 PM
December 25, 2025 at 7:27 PM
Reposted
‘The value of the world’s top ten companies is $25.6 trillion. Of that, $15.1 trillion has accumulated since 30 November 2022 and is directly linked to the AI boom.’

John Lanchester on the AI bubble.

www.lrb.co.uk/the-paper/v4...
John Lanchester · King of Cannibal Island: Will the AI bubble burst?
Nvidia shares are the purest bet you can make on the impact of AI. The leading firms are lending money to one another in...
www.lrb.co.uk
December 25, 2025 at 9:39 AM
Reposted
East Coast Trail - a large sea arch. I’m in the pic:)...for scale. Newfoundland, Canada. #hiking #trail #backpacking
December 24, 2025 at 6:38 PM
Reposted
Emotions are by nature unstable. Otherwise we couldn’t recognize any change.

Trying to stabilize emotions is suffering. Imagining to be responsible for them is suffering too.

But you are not that. You are the stability behind their movements. You are the riverbed in which they flow.
December 25, 2025 at 9:04 AM
Reposted
Scientists reverse Alzheimer’s in mice and restore memory. For more than 100 years, Alzheimer’s disease has been treated as a one-way decline—but new research is aiming for a cure.
www.sciencedaily.com/releases/202...
Scientists reverse Alzheimer’s in mice and restore memory
Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and restorin...
www.sciencedaily.com
December 25, 2025 at 4:22 AM
Reposted
If ICE can threaten arrest for filming, then journalists, watchdogs, and protesters can all be silenced the same way. You don’t have freedom of the press if recording police is treated as terrorism.  #holdfast

www.cato.org/blog/dhs-pol...
The Government Unconstitutionally Labels ICE Observers as Domestic Terrorists
A free country must have an absolute wall of protection for those who record government actions.
www.cato.org
December 24, 2025 at 8:08 PM
Reposted
He and his people have decimated our ability to adequately defend this country. One well-placed strike and our country, possibly the whole world, is over in a couple of hours.
December 24, 2025 at 11:48 PM
Reposted
A 17-year-old worker died at a pork producer in Nebraska run by the governor’s family. Two investigations later, the boy’s mother is still searching for answers. trib.al/z7ZUF62
December 24, 2025 at 6:09 PM
December 25, 2025 at 5:22 PM