Amanda Elton
@amandaelton.bsky.social
Assistant professor at the University of Florida.
fMRI, addiction, alcohol, early life stress, resilience, cognitive neuroscience
fMRI, addiction, alcohol, early life stress, resilience, cognitive neuroscience
Pinned
Amanda Elton
@amandaelton.bsky.social
· Dec 2
The effects of adverse life events on brain development in the ABCD study®: a propensity-weighted analysis - Molecular Psychiatry
Molecular Psychiatry - The effects of adverse life events on brain development in the ABCD study®: a propensity-weighted analysis
www.nature.com
Our recent work looking at adverse life events and resting-state functional connectivity in the ABCD study now available online www.nature.com/articles/s41...
Key findings:
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Key findings:
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Reposted by Amanda Elton
Really interesting approach to mood regulation!
news.harvard.edu/gazette/stor...
news.harvard.edu/gazette/stor...
Wearable patch reduces cravings for alcohol and drugs — Harvard Gazette
First year of recovery is “immensely challenging,” researchers note. New device could be a difference maker.
news.harvard.edu
October 2, 2025 at 11:28 AM
Really interesting approach to mood regulation!
news.harvard.edu/gazette/stor...
news.harvard.edu/gazette/stor...
Got a NOA for a new R01 from #NIAAA this week. Looks like new awards are finally moving! Also year two is already listed as pending?
fireworks are displayed over a body of water in the night sky
ALT: fireworks are displayed over a body of water in the night sky
media.tenor.com
September 12, 2025 at 6:38 PM
Got a NOA for a new R01 from #NIAAA this week. Looks like new awards are finally moving! Also year two is already listed as pending?
Reposted by Amanda Elton
Updating my analysis now that August data should be relatively complete.
Not great news...
The rate of investment of the appropriation is not increasing and it seems unlikely that the entire appropriation will be committed this year.
1/2
Not great news...
The rate of investment of the appropriation is not increasing and it seems unlikely that the entire appropriation will be committed this year.
1/2
September 8, 2025 at 6:29 PM
Updating my analysis now that August data should be relatively complete.
Not great news...
The rate of investment of the appropriation is not increasing and it seems unlikely that the entire appropriation will be committed this year.
1/2
Not great news...
The rate of investment of the appropriation is not increasing and it seems unlikely that the entire appropriation will be committed this year.
1/2
#NIAAA funded 5 new R01s last week, bringing the FY25 total to 13. 10 of 50 grants funded last week were new (not renewals). Perhaps marks a shift towards funding of new awards in the final stretch?
September 8, 2025 at 2:04 PM
#NIAAA funded 5 new R01s last week, bringing the FY25 total to 13. 10 of 50 grants funded last week were new (not renewals). Perhaps marks a shift towards funding of new awards in the final stretch?
Family history of alcohol use problems increases reward-related brain activity, leading to increased drinking trajectories in young adults. New preprint: www.medrxiv.org/content/10.1... #addiction #fMRI #NIAAA 1/5
Delay Discounting, Nucleus Accumbens Activation, and Alcohol Use Trajectories in Young Adults with a Family History of Alcohol Use Disorder
A family history (FH) of alcohol use disorder (AUD) is associated with increased personal risk for alcohol misuse and AUD. FH is also related to increased impulsivity as evidenced by performance on de...
www.medrxiv.org
September 8, 2025 at 11:59 AM
Family history of alcohol use problems increases reward-related brain activity, leading to increased drinking trajectories in young adults. New preprint: www.medrxiv.org/content/10.1... #addiction #fMRI #NIAAA 1/5
Reposted by Amanda Elton
The numbers for #NIAAA are especially bleak. No new (Type 1) NIAAA awards posted on Reporter last week. With 4 weeks to go, there is an immense amount of ground to make up to ensure that novel alcohol research is supported and investigators can support their work, their staff and trainees.
One month to go for NIH grants in the FY2025 cycle drugmonkey.wordpress.com/2025/09/02/o...
One month to go for NIH grants in the FY2025 cycle
As of today*, the NIH has funded 2,479 new (Type 1) R01 projects for Fiscal Year 2025. This FY expires at the end of the month, so we have four more weeks to go. For reference, NIH funded 4,612 new…
drugmonkey.wordpress.com
September 2, 2025 at 7:48 PM
The numbers for #NIAAA are especially bleak. No new (Type 1) NIAAA awards posted on Reporter last week. With 4 weeks to go, there is an immense amount of ground to make up to ensure that novel alcohol research is supported and investigators can support their work, their staff and trainees.
Reposted by Amanda Elton
I'm thrilled to announce that I just got my first R01 from NIAAA! 1R01AA031007. I'm hiring here in Baton Rouge, LA, so message me if you are interested in working on this alcohol grant, or on other projects in lab involving opioid use!
August 23, 2025 at 3:48 PM
I'm thrilled to announce that I just got my first R01 from NIAAA! 1R01AA031007. I'm hiring here in Baton Rouge, LA, so message me if you are interested in working on this alcohol grant, or on other projects in lab involving opioid use!
So are we all resubmitting next cycle, or what?
NIH progress on new R01s in FY 2025 drugmonkey.wordpress.com/2025/08/18/n...
NIH progress on new R01s in FY 2025
I know Doctor Editor Director Professor Berg has more sophisticated analyses going but this simple data set made sense to me once I realized how few new R01 NIAAA has issued so far (5). Since we ar…
drugmonkey.wordpress.com
August 19, 2025 at 12:42 PM
So are we all resubmitting next cycle, or what?
Reposted by Amanda Elton
NIH progress on new R01s in FY 2025 drugmonkey.wordpress.com/2025/08/18/n...
NIH progress on new R01s in FY 2025
I know Doctor Editor Director Professor Berg has more sophisticated analyses going but this simple data set made sense to me once I realized how few new R01 NIAAA has issued so far (5). Since we ar…
drugmonkey.wordpress.com
August 19, 2025 at 1:56 AM
NIH progress on new R01s in FY 2025 drugmonkey.wordpress.com/2025/08/18/n...
Reposted by Amanda Elton
Adverse experiences in early life affect brain development. A Review in Nature Reviews Neuroscience discusses evidence for how these adversity-induced changes to human brain architecture alter developmental trajectories that may underpin adult psychopathology. go.nature.com/45xZOii 🔒
August 18, 2025 at 4:19 PM
Adverse experiences in early life affect brain development. A Review in Nature Reviews Neuroscience discusses evidence for how these adversity-induced changes to human brain architecture alter developmental trajectories that may underpin adult psychopathology. go.nature.com/45xZOii 🔒
Reposted by Amanda Elton
College students pursuing careers in science or medicine can learn skills for grad school through the Summer Neuroscience Internship Program at the University of Florida, now celebrating its 10th year. SNIP provides mentorship, hands-on lab work and more.
Learn more: bit.ly/4kdYPJC
Learn more: bit.ly/4kdYPJC
June 23, 2025 at 3:49 PM
College students pursuing careers in science or medicine can learn skills for grad school through the Summer Neuroscience Internship Program at the University of Florida, now celebrating its 10th year. SNIP provides mentorship, hands-on lab work and more.
Learn more: bit.ly/4kdYPJC
Learn more: bit.ly/4kdYPJC
Reposted by Amanda Elton
fMRI Peeps - I remember reading a paper, years ago, focused on identifying regions for brain-association analyses based on peak inter-individual variance (rather than peak activation), but a 20-min search failed to recover it. Suggestions? Thx!
May 23, 2025 at 1:47 PM
fMRI Peeps - I remember reading a paper, years ago, focused on identifying regions for brain-association analyses based on peak inter-individual variance (rather than peak activation), but a 20-min search failed to recover it. Suggestions? Thx!
Reposted by Amanda Elton
👏👏👏
fMRIPrep Lifespan: Extending A Robust Pipeline for Functional MRI Preprocessing to Developmental Neuroimaging | bioRxiv www.biorxiv.org/content/10.1...
fMRIPrep Lifespan: Extending A Robust Pipeline for Functional MRI Preprocessing to Developmental Neuroimaging | bioRxiv www.biorxiv.org/content/10.1...
May 19, 2025 at 1:06 AM
👏👏👏
fMRIPrep Lifespan: Extending A Robust Pipeline for Functional MRI Preprocessing to Developmental Neuroimaging | bioRxiv www.biorxiv.org/content/10.1...
fMRIPrep Lifespan: Extending A Robust Pipeline for Functional MRI Preprocessing to Developmental Neuroimaging | bioRxiv www.biorxiv.org/content/10.1...
Reposted by Amanda Elton
Psychiatric disorders share genetic roots, but the mechanisms are unclear. With exon-level brain data, we linked common & rare variants to 110 core genes in pathways such as cortisol & dopamine cascades, mainly in excitatory neurons, offering new therapeutic targets 🧠✨ www.nature.com/articles/s41...
Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons - Translational Psychiatry
Translational Psychiatry - Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons
www.nature.com
April 21, 2025 at 10:27 AM
Psychiatric disorders share genetic roots, but the mechanisms are unclear. With exon-level brain data, we linked common & rare variants to 110 core genes in pathways such as cortisol & dopamine cascades, mainly in excitatory neurons, offering new therapeutic targets 🧠✨ www.nature.com/articles/s41...
💯
The result of a large (42 authors!) collaboration:
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
April 11, 2025 at 7:08 PM
💯
New study in JAACAP with wonderful collaborators, Shanting Chen and Catalina Lopez-Quintero: Racial discrimination alters subcortical brain connections in minority youth, speeding up maturation. Changes tied to mental health issues, especially in girls #ABCDStudy authors.elsevier.com/sd/article/S...
April 11, 2025 at 3:14 PM
New study in JAACAP with wonderful collaborators, Shanting Chen and Catalina Lopez-Quintero: Racial discrimination alters subcortical brain connections in minority youth, speeding up maturation. Changes tied to mental health issues, especially in girls #ABCDStudy authors.elsevier.com/sd/article/S...
Reposted by Amanda Elton
⚕️ NEW RESEARCH! 🧠 👀
Haque et al. report a case of chronic alcohol use disorder #AUD that had reduced cravings & stopped drinking following a traumatic brain injury that damaged frontal lobe connectivity.
https://bit.ly/44k6WzN
#addictionsci #BrainInjury
Haque et al. report a case of chronic alcohol use disorder #AUD that had reduced cravings & stopped drinking following a traumatic brain injury that damaged frontal lobe connectivity.
https://bit.ly/44k6WzN
#addictionsci #BrainInjury
Remission of alcohol use disorder following traumatic brain injury with focal orbitofrontal cortex hemorrhage: case report and network mapping - Communications Medicine
Haque et al. report a case of chronic alcohol use disorder that had early remission following a traumatic brain injury with left orbitofrontal cortex intracerebral hemorrhage. Mapping of this lesion converges on recently described addictive behavior network maps, but with inverse connectivity.
bit.ly
April 8, 2025 at 11:31 AM
⚕️ NEW RESEARCH! 🧠 👀
Haque et al. report a case of chronic alcohol use disorder #AUD that had reduced cravings & stopped drinking following a traumatic brain injury that damaged frontal lobe connectivity.
https://bit.ly/44k6WzN
#addictionsci #BrainInjury
Haque et al. report a case of chronic alcohol use disorder #AUD that had reduced cravings & stopped drinking following a traumatic brain injury that damaged frontal lobe connectivity.
https://bit.ly/44k6WzN
#addictionsci #BrainInjury
Reposted by Amanda Elton
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health
Major mental disorders are increasingly understood as disorders of brain development. Large and heterogeneous samples are required to define generalizable links between brain development and psychopat...
doi.org
February 27, 2025 at 8:57 PM
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reposted by Amanda Elton
Confirmed (by many sources) news about 50 NIH Study Sections being allowed to announce meetings in the Federal Register.
As usual, MANY more questions than answers...
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As usual, MANY more questions than answers...
1/2
a muppet news anchor says " and now a muppet news flash " while holding a piece of paper
ALT: a muppet news anchor says " and now a muppet news flash " while holding a piece of paper
media.tenor.com
February 26, 2025 at 7:57 PM
Confirmed (by many sources) news about 50 NIH Study Sections being allowed to announce meetings in the Federal Register.
As usual, MANY more questions than answers...
1/2
As usual, MANY more questions than answers...
1/2
Reposted by Amanda Elton
New Hurd Lab paper in Molecular Psychiatry explores how cannabidiol can help reduce anxiety linked to specific triggers.
Learn more about our findings 🧵 and read the full paper here: www.nature.com/articles/s41... (1/7) #Neuroskyence #WomenInSTEM #CBD
Learn more about our findings 🧵 and read the full paper here: www.nature.com/articles/s41... (1/7) #Neuroskyence #WomenInSTEM #CBD
February 18, 2025 at 9:09 PM
New Hurd Lab paper in Molecular Psychiatry explores how cannabidiol can help reduce anxiety linked to specific triggers.
Learn more about our findings 🧵 and read the full paper here: www.nature.com/articles/s41... (1/7) #Neuroskyence #WomenInSTEM #CBD
Learn more about our findings 🧵 and read the full paper here: www.nature.com/articles/s41... (1/7) #Neuroskyence #WomenInSTEM #CBD
Reposted by Amanda Elton
Would be great to ask about Advisory Council meetings too. How many people (like me) have a grant that was scored favorably but still see 'pending council review' on ERA Commons? As I understand it no ACs have met since 1/20/25 ie no new grants have been approved in any institute. Is that true?
February 18, 2025 at 5:39 PM
Would be great to ask about Advisory Council meetings too. How many people (like me) have a grant that was scored favorably but still see 'pending council review' on ERA Commons? As I understand it no ACs have met since 1/20/25 ie no new grants have been approved in any institute. Is that true?
Reposted by Amanda Elton
So it looks like you can look this up here: www.csr.nih.gov/RevPanelsAnd...
(Sort by date, see screenshot). The ones that are cancelled have an asterisk. For today 2/18, there are 8 meetings, of which 3 are cancelled. Those 3 are not in the federal register. Seems the others are.
(Sort by date, see screenshot). The ones that are cancelled have an asterisk. For today 2/18, there are 8 meetings, of which 3 are cancelled. Those 3 are not in the federal register. Seems the others are.
February 18, 2025 at 4:19 PM
So it looks like you can look this up here: www.csr.nih.gov/RevPanelsAnd...
(Sort by date, see screenshot). The ones that are cancelled have an asterisk. For today 2/18, there are 8 meetings, of which 3 are cancelled. Those 3 are not in the federal register. Seems the others are.
(Sort by date, see screenshot). The ones that are cancelled have an asterisk. For today 2/18, there are 8 meetings, of which 3 are cancelled. Those 3 are not in the federal register. Seems the others are.
Reposted by Amanda Elton
Now, with the Reporter data, we can see what the ratio of indirect to total cost for these institutions were:
17/n
17/n
February 13, 2025 at 4:07 AM
Now, with the Reporter data, we can see what the ratio of indirect to total cost for these institutions were:
17/n
17/n
Reposted by Amanda Elton
🏠📉 New research in @jama.com (JAMA Network Open) highlights the impact of housing instability on children's mental health. We explored how stress about eviction or housing loss affects child depression, anxiety, ADHD, & behavioral problems.
#HousingInstability
jamanetwork.com/journals/jam... /1
#HousingInstability
jamanetwork.com/journals/jam... /1
Stress About Eviction or Loss of Housing and Child Mental Health
This cross-sectional study examines the association of stress about eviction or the loss of housing with caregiver-reported depression, anxiety, attention-deficit/hyperactivity disorder, and behaviora...
jamanetwork.com
February 12, 2025 at 6:43 PM
🏠📉 New research in @jama.com (JAMA Network Open) highlights the impact of housing instability on children's mental health. We explored how stress about eviction or housing loss affects child depression, anxiety, ADHD, & behavioral problems.
#HousingInstability
jamanetwork.com/journals/jam... /1
#HousingInstability
jamanetwork.com/journals/jam... /1
Reposted by Amanda Elton
Bluetorial: Potential impact of “NIH” “plan” regarding indirect costs on institutions
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
February 11, 2025 at 6:48 PM
Bluetorial: Potential impact of “NIH” “plan” regarding indirect costs on institutions