Yes, unfortunately it affects so many families and is so multifaceted. I wish the best for your nieces and the rest of the family!

This NIH-funded study helps us understand more about the brain mechanisms of familial risk for alcohol use disorder, which can help us develop new methods to improve health outcomes for people who are at risk for addiction. 5/5

Family history was related to greater activation in the nucleus accumbens, suggesting a heightened sensitivity to rewards, but not with brain differences in future thinking or cognitive control. Greater nucleus accumbens activation was also related to steeper escalations in alcohol drinking. 4/5

We examined brain systems for future thinking, cognitive control, and reward processing during an fMRI delay discounting task and tested these as mediators of the relationship between family history and alcohol drinking trajectories. 3/5

Family history is associated with more impulsive decision-making and greater alcohol use. We hypothesized that these relationships are driven by particular brain differences in regions that contribute to decision-making for delayed vs. immediate rewards. 2/5

They seem to be prioritizing type 5 grants right now, around 10 per day in August.... Not sure how many of those they need to get through PO told me to expect a "funding decision" for my pending grant before 9/30 😬

Actually 33 (one new)!

Only last week one for NIAAA...?

access link: authors.elsevier.com/a/1l8AV3AZg%...