Natalie Matosin
@nataliematosin.bsky.social
Neurobiologist // Mother // Waterwoman
Head of the @MINDSLab.bsky.social
Wake up kids, we got the dreamer’s disease
📍The University of Sydney
🔗 https://mindslaboratory.wordpress.com
Head of the @MINDSLab.bsky.social
Wake up kids, we got the dreamer’s disease
📍The University of Sydney
🔗 https://mindslaboratory.wordpress.com
Pinned
Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling
Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear. Here, we probed the di...
www.biorxiv.org
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Fabulous job on this paper, check it out if you haven't yet.
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Transcriptomic Analysis of the Human Habenula in Schizophrenia | American Journal of Psychiatry
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
doi.org
November 9, 2025 at 6:33 PM
Fabulous job on this paper, check it out if you haven't yet.
Reposted by Natalie Matosin
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Transcriptomic Analysis of the Human Habenula in Schizophrenia | American Journal of Psychiatry
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
doi.org
November 4, 2025 at 9:31 PM
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Reposted by Natalie Matosin
New lab paper! @sophiedebs.bsky.social and @nataliematosin.bsky.social discuss a recent study from LIBD investigating the transcriptomic landscape of the human habenula in schizophrenia
🧠 Our editorial: psychiatryonline.org/doi/10.1176/...
📜 The original study: psychiatryonline.org/doi/10.1176/...
🧠 Our editorial: psychiatryonline.org/doi/10.1176/...
📜 The original study: psychiatryonline.org/doi/10.1176/...
November 3, 2025 at 5:54 AM
New lab paper! @sophiedebs.bsky.social and @nataliematosin.bsky.social discuss a recent study from LIBD investigating the transcriptomic landscape of the human habenula in schizophrenia
🧠 Our editorial: psychiatryonline.org/doi/10.1176/...
📜 The original study: psychiatryonline.org/doi/10.1176/...
🧠 Our editorial: psychiatryonline.org/doi/10.1176/...
📜 The original study: psychiatryonline.org/doi/10.1176/...
Thanks to BPA for receiving the work so well and all the positive feedback. The conference was a huge success, well done to Leigh and Alex and the LOC. Looking forward to the Australasian Neuroscience Alliance meeting in Sydney next year!
Starting the afternoon with the 16th Aubrey Lewis Award Lecture at the #BPA2025, presented by Dr Natalie Matosin
October 28, 2025 at 10:10 PM
Thanks to BPA for receiving the work so well and all the positive feedback. The conference was a huge success, well done to Leigh and Alex and the LOC. Looking forward to the Australasian Neuroscience Alliance meeting in Sydney next year!
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling
Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear. Here, we probed the di...
www.biorxiv.org
September 25, 2025 at 10:12 PM
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Wonderful visits, highlighted the need for face-to-face interactions. Cant wait for all our upcoming collabs 🙌 thanks for carving time out to come see us @drcricru.bsky.social @nikosdaskalakis.bsky.social @rcbagot.bsky.social
Grateful to host @drcricru.bsky.social, @nikosdaskalakis.bsky.social & @rcbagot.bsky.social at USYD over the last few months. Your talks highlighted the importance of our field and understanding stress in mental illness. Lots of new ideas for future collaborations. Thanks for coming!
August 17, 2025 at 8:12 AM
Wonderful visits, highlighted the need for face-to-face interactions. Cant wait for all our upcoming collabs 🙌 thanks for carving time out to come see us @drcricru.bsky.social @nikosdaskalakis.bsky.social @rcbagot.bsky.social
Microdosing delight to combat stress; interesting concept, backed by neuroscience. Was a pleasure to comment on the very excellent work of @drrachelbarr.bsky.social on how the experience of delight can tune down our stress response. @brainandmindcentre.bsky.social www.smh.com.au/lifestyle/he...
As we stress more than ever, is it time to ‘microdose delight’?
Our brains are not built to handle the daily threats modern humans face. But there’s a trick that may help them.
www.smh.com.au
August 11, 2025 at 10:03 AM
Microdosing delight to combat stress; interesting concept, backed by neuroscience. Was a pleasure to comment on the very excellent work of @drrachelbarr.bsky.social on how the experience of delight can tune down our stress response. @brainandmindcentre.bsky.social www.smh.com.au/lifestyle/he...
BIOLOGICAL STRESS
It’s wild that “species” is one of the most fundamental concepts in biology but we can’t really define it & there are LOTS of organisms that experts disagree about. Are there other concepts in science that seem simple from the outside but are actually complicated? Plz dish the drama in your field🧪🧬🦠
What defines a species? Inside the fierce debate that's rocking biology to its core
The question of what defines a species has vexed scientists across the ages, particularly in conservation, where decisions require a firm understanding of biodiversity.
www.livescience.com
August 5, 2025 at 6:57 AM
BIOLOGICAL STRESS
Reposted by Natalie Matosin
US children's health has worsened from 2007 to 2023 across various indicators, including mortality, chronic conditions, and mental health.
ja.ma/4lZnRxG #MedSky #PedSky
ja.ma/4lZnRxG #MedSky #PedSky
August 2, 2025 at 10:00 AM
US children's health has worsened from 2007 to 2023 across various indicators, including mortality, chronic conditions, and mental health.
ja.ma/4lZnRxG #MedSky #PedSky
ja.ma/4lZnRxG #MedSky #PedSky
Reposted by Natalie Matosin
This title!
“What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review.”
www.cambridge.org/core/journal...
“What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review.”
www.cambridge.org/core/journal...
What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review | Behavioural and Cognitive Psychotherapy | Cambridge Core
What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review
www.cambridge.org
August 2, 2025 at 12:20 PM
This title!
“What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review.”
www.cambridge.org/core/journal...
“What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review.”
www.cambridge.org/core/journal...
Reminder that applications are due this week!
📢 Help us progress our research! Opportunity to join our team.
We are recruiting a Research Assistant/Lab Manager. If you have experience in supporting a lab and tissue handling experience, we'd love to hear from you
Closes Sunday 20 July 2025 11:59
usyd.wd105.myworkdayjobs.com/USYD_EXTERNA...
We are recruiting a Research Assistant/Lab Manager. If you have experience in supporting a lab and tissue handling experience, we'd love to hear from you
Closes Sunday 20 July 2025 11:59
usyd.wd105.myworkdayjobs.com/USYD_EXTERNA...
Research Officer
Full time fixed term contract for one year Exciting opportunity to drive research to better understand how stress raises risk for mental illness using a broad range of cutting-edge techniques and anal...
usyd.wd105.myworkdayjobs.com
July 16, 2025 at 12:18 AM
Reminder that applications are due this week!
Looking for the next member of our team to support our ongoing projects. Check out the PD and if you think you're a fit, please apply!
📢 Help us progress our research! Opportunity to join our team.
We are recruiting a Research Assistant/Lab Manager. If you have experience in supporting a lab and tissue handling experience, we'd love to hear from you
Closes Sunday 20 July 2025 11:59
usyd.wd105.myworkdayjobs.com/USYD_EXTERNA...
We are recruiting a Research Assistant/Lab Manager. If you have experience in supporting a lab and tissue handling experience, we'd love to hear from you
Closes Sunday 20 July 2025 11:59
usyd.wd105.myworkdayjobs.com/USYD_EXTERNA...
Research Officer
Full time fixed term contract for one year Exciting opportunity to drive research to better understand how stress raises risk for mental illness using a broad range of cutting-edge techniques and anal...
usyd.wd105.myworkdayjobs.com
July 7, 2025 at 6:39 AM
Looking for the next member of our team to support our ongoing projects. Check out the PD and if you think you're a fit, please apply!
This is important
Hello & HAPPY FRIDAY, as promised an open letter by my lovely colleagues and myself. Everybody, feel free to sign this even if you are not NL-based and ‼️ share ‼️ (anonymous signature is poss):
Open Letter: Stop the Uncritical Adoption of AI Technologies in Academia
openletter.earth/open-letter-...
Open Letter: Stop the Uncritical Adoption of AI Technologies in Academia
openletter.earth/open-letter-...
June 27, 2025 at 9:25 PM
This is important
A pleasure to spend the last week with @drcricru.bsky.social - to share her fascinating work on brain/placenta with my colleagues at @Sydney_Uni and introduce her to our beautiful city + home. So lucky to have had extended time to bounce ideas and ponder life with this brilliant mind✨
June 23, 2025 at 9:50 AM
A pleasure to spend the last week with @drcricru.bsky.social - to share her fascinating work on brain/placenta with my colleagues at @Sydney_Uni and introduce her to our beautiful city + home. So lucky to have had extended time to bounce ideas and ponder life with this brilliant mind✨
Reposted by Natalie Matosin
Check out our new paper led by the MINDS Lab original mass spec baddie @katrinazedmond.bsky.social 💃
🚨 NEW PAPER 🚨
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Expanding our understanding of (mal)adapted stress physiology in psychiatric disorders: achieving single-cell characterisation of steroids and neuropeptides
Steroid hormones and neurosteroids (collectively neuroactive steroids), alongside neuropeptides, are key modulators of the central nervous system. The…
sciencedirect.com
June 10, 2025 at 10:41 PM
Check out our new paper led by the MINDS Lab original mass spec baddie @katrinazedmond.bsky.social 💃
🚨 NEW PAPER 🚨
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Expanding our understanding of (mal)adapted stress physiology in psychiatric disorders: achieving single-cell characterisation of steroids and neuropeptides
Steroid hormones and neurosteroids (collectively neuroactive steroids), alongside neuropeptides, are key modulators of the central nervous system. The…
sciencedirect.com
June 10, 2025 at 10:40 PM
🚨 NEW PAPER 🚨
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Unbelievable to think about what this is doing at the health level and a focus of the #sydneyhorizonfellows
Analyses in Nature suggest that about 52% of people born in 2020 will experience unprecedented exposure to heatwaves alone under a 1.5 °C warming scenario, compared with 16% of those born in 1960. go.nature.com/3GYQZFq 🧪
May 13, 2025 at 1:54 AM
Unbelievable to think about what this is doing at the health level and a focus of the #sydneyhorizonfellows
Thrilled that @rcbagot.bsky.social will be visiting us at The University of Sydney and delivering a Flagship seminar on August 11 on the mechanisms of resilience. Please join by registering here
events.humanitix.com/soms-flagshi...
events.humanitix.com/soms-flagshi...
Uh oh, we can’t find that page.
The page you were looking for doesn’t exist, isn’t available, or was loading incorrectly.
events.humanitix.com
May 8, 2025 at 2:07 AM
Thrilled that @rcbagot.bsky.social will be visiting us at The University of Sydney and delivering a Flagship seminar on August 11 on the mechanisms of resilience. Please join by registering here
events.humanitix.com/soms-flagshi...
events.humanitix.com/soms-flagshi...
Reposted by Natalie Matosin
Yes - Biological Psychiatry Australia is now on Bluesky! Please follow us for #biologicalpsychiatry research news
Watch this space! 👀
Watch this space! 👀
Biological Psychiatry Australia @biolpsychaust.bsky.social have joined Bluesky!
If you are a #biologicalpsychiatry #molecularpsychiatry researcher, give them a follow for research and news in this exciting area of research #neuroskyence
If you are a #biologicalpsychiatry #molecularpsychiatry researcher, give them a follow for research and news in this exciting area of research #neuroskyence
May 8, 2025 at 12:02 AM
Yes - Biological Psychiatry Australia is now on Bluesky! Please follow us for #biologicalpsychiatry research news
Watch this space! 👀
Watch this space! 👀
Biological Psychiatry Australia @biolpsychaust.bsky.social have joined Bluesky!
If you are a #biologicalpsychiatry #molecularpsychiatry researcher, give them a follow for research and news in this exciting area of research #neuroskyence
If you are a #biologicalpsychiatry #molecularpsychiatry researcher, give them a follow for research and news in this exciting area of research #neuroskyence
May 7, 2025 at 9:00 PM
Biological Psychiatry Australia @biolpsychaust.bsky.social have joined Bluesky!
If you are a #biologicalpsychiatry #molecularpsychiatry researcher, give them a follow for research and news in this exciting area of research #neuroskyence
If you are a #biologicalpsychiatry #molecularpsychiatry researcher, give them a follow for research and news in this exciting area of research #neuroskyence
I spent all day doing finances which was a bit miserable, so here’s a timeline cleanse 🩵✨
May 7, 2025 at 8:53 AM
I spent all day doing finances which was a bit miserable, so here’s a timeline cleanse 🩵✨
Psychiatric disorders share genetic roots, but the mechanisms are unclear. With exon-level brain data, we linked common & rare variants to 110 core genes in pathways such as cortisol & dopamine cascades, mainly in excitatory neurons, offering new therapeutic targets 🧠✨ www.nature.com/articles/s41...
Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons - Translational Psychiatry
Translational Psychiatry - Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons
www.nature.com
April 21, 2025 at 10:27 AM
Psychiatric disorders share genetic roots, but the mechanisms are unclear. With exon-level brain data, we linked common & rare variants to 110 core genes in pathways such as cortisol & dopamine cascades, mainly in excitatory neurons, offering new therapeutic targets 🧠✨ www.nature.com/articles/s41...