Well not most of the day, but try to get out of the house and down there daily!

I am very lucky to call this my backyard!

Our findings highlight astrocytes as crucial players in how exposure to severe adversity raises risk to psychopathology and position them as strategic pharmacological targets for future intervention strategies.

Read more here: www.biorxiv.org/content/10.1...

Human pluripotent stem cell-derived astrocytes from both two- and three-dimensional models confirmed that glutamate signalling is directly impacted by glucocorticoid activation.

Early-life adversity exposure produced more pronounced cellular changes than adversity experienced later in life, and female cases displayed stronger transcriptomic associations than males with adversity exposure.

In individuals with psychiatric disorders and high adversity exposure, we identified distinct alterations to glutamate-related synaptic functions, supported by histological quantification of >20,000 astrocytes.

We probed the diversity of ∼145,000 total human cortical astrocytes with single nucleus and spatial transcriptomics, and showed that human astrocytes comprise a molecularly and anatomically diverse cell population.

The newspaper did say they reached out to you! I’m looking forward to reading your book, love your work 🩵

Note that we are only looking for candidates already in Australia for this position as we need to get started ASAP!