Andrea Manca
@amancayork.bsky.social
Health Economist
@CHE @UniofYork |
Methods & Applied HEOR | HTA |
Economic Evaluation | CEA | Evidence Synthesis | DCE |
Modelling & IPD Analyses | RCTs | RWD | Causal Inference |
Foodie | Skiing | Martial Arts | Travel Personal views | RT not endorsement
@CHE @UniofYork |
Methods & Applied HEOR | HTA |
Economic Evaluation | CEA | Evidence Synthesis | DCE |
Modelling & IPD Analyses | RCTs | RWD | Causal Inference |
Foodie | Skiing | Martial Arts | Travel Personal views | RT not endorsement
We are seeking to recruit a Senior Research Fellow / Reader to join the Centre for Health Economics at @york.ac.uk
More details can be found in the advert
jobs.york.ac.uk/vacancy/seni...
More details can be found in the advert
jobs.york.ac.uk/vacancy/seni...
Jobs - The University of York
jobs.york.ac.uk
November 14, 2025 at 10:46 AM
We are seeking to recruit a Senior Research Fellow / Reader to join the Centre for Health Economics at @york.ac.uk
More details can be found in the advert
jobs.york.ac.uk/vacancy/seni...
More details can be found in the advert
jobs.york.ac.uk/vacancy/seni...
Reposted by Andrea Manca
Very lucky to have @jamiecummins.bsky.social as a STAR editor at Psych Science, helping us navigate these kinds of issues. This is such important work.
Can large language models stand in for human participants?
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
The threat of analytic flexibility in using large language models to simulate human data: A call to attention
Social scientists are now using large language models to create "silicon samples" - synthetic datasets intended to stand in for human respondents, aimed at revolutionising human subjects research. How...
arxiv.org
September 19, 2025 at 10:27 PM
Very lucky to have @jamiecummins.bsky.social as a STAR editor at Psych Science, helping us navigate these kinds of issues. This is such important work.
Just 2 weeks to go to our residential course on advanced statistical methods in economic evaluation for HTA which will be held in beautiful city of York.
Do you want to expand your professional competence in HTA? Register to attend the Statistical Methods in Economic Evaluation for HTA - Advanced Course at the University of York🚀 @CHEyork
www.york.ac.uk/che/courses/...
www.york.ac.uk/che/courses/...
Statistical Methods in Economic Evaluation for HTA - Advanced
Dates - Tuesday 9th - Thursday 11th September 2025
The course will run from 9:00am to 6:00pm BST (GMT+1) on the first day and from 9:30am to 5:00pm on the next two days.
In-person (University of York...
www.york.ac.uk
August 28, 2025 at 7:40 PM
Just 2 weeks to go to our residential course on advanced statistical methods in economic evaluation for HTA which will be held in beautiful city of York.
Reposted by Andrea Manca
Please share with your network.
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Statistical Methods in Economic Evaluation for HTA - Advanced
Dates - Tuesday 9th - Thursday 11th September 2025
The course will run from 9:00am to 6:00pm BST (GMT+1) on the first day and from 9:30am to 5:00pm on the next two days.
In-person (University of York...
www.york.ac.uk
July 8, 2025 at 6:28 PM
Please share with your network.
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Do you want to expand your professional competence in HTA? Register to attend the Statistical Methods in Economic Evaluation for HTA - Advanced Course at the University of York🚀 @CHEyork
www.york.ac.uk/che/courses/...
www.york.ac.uk/che/courses/...
Statistical Methods in Economic Evaluation for HTA - Advanced
Dates - Tuesday 9th - Thursday 11th September 2025
The course will run from 9:00am to 6:00pm BST (GMT+1) on the first day and from 9:30am to 5:00pm on the next two days.
In-person (University of York...
www.york.ac.uk
July 12, 2025 at 6:18 AM
Do you want to expand your professional competence in HTA? Register to attend the Statistical Methods in Economic Evaluation for HTA - Advanced Course at the University of York🚀 @CHEyork
www.york.ac.uk/che/courses/...
www.york.ac.uk/che/courses/...
Please share with your network.
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Statistical Methods in Economic Evaluation for HTA - Advanced
Dates - Tuesday 9th - Thursday 11th September 2025
The course will run from 9:00am to 6:00pm BST (GMT+1) on the first day and from 9:30am to 5:00pm on the next two days.
In-person (University of York...
www.york.ac.uk
July 8, 2025 at 6:28 PM
Please share with your network.
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
3-day Advanced Course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Reposted by Andrea Manca
How do research careers compare across countries? New global database has some answers
Online tool from the Research and Innovation Careers Observatory allows users to compare salary, typical career destinations, and more
www.science.org/content/arti...
Online tool from the Research and Innovation Careers Observatory allows users to compare salary, typical career destinations, and more
www.science.org/content/arti...
How do research careers compare across countries? New global database has some answers
Online tool from the Research and Innovation Careers Observatory allows users to compare salary, typical career destinations, and more
www.science.org
July 1, 2025 at 3:43 PM
How do research careers compare across countries? New global database has some answers
Online tool from the Research and Innovation Careers Observatory allows users to compare salary, typical career destinations, and more
www.science.org/content/arti...
Online tool from the Research and Innovation Careers Observatory allows users to compare salary, typical career destinations, and more
www.science.org/content/arti...
Reposted by Andrea Manca
At #CCR25, we saw some trials use a #CompositeOutcome (an endpoint that combines more than one outcome into a single measure) & also saw some of the problems these can throw up. I have discussed these before but thought it would be useful to revisit 1/9
#MethodologyMonday #120
#MethodologyMonday #120
June 16, 2025 at 5:56 AM
At #CCR25, we saw some trials use a #CompositeOutcome (an endpoint that combines more than one outcome into a single measure) & also saw some of the problems these can throw up. I have discussed these before but thought it would be useful to revisit 1/9
#MethodologyMonday #120
#MethodologyMonday #120
@CHEyork @UoY_BizTraining @UniOfYork short courses are run face to face in beautiful York, where you’ll be able to meet and spend time interacting with our faculty of experts as well as network with other participants from the industry, consultancy and academia
www.york.ac.uk/che/courses/...
www.york.ac.uk/che/courses/...
Statistical Methods in Economic Evaluation for HTA - Advanced
Dates - Tuesday 9th - Thursday 11th September 2025
The course will run from 9:00am to 6:00pm BST (GMT+1) on the first day and from 9:30am to 5:00pm on the next two days.
In-person (University of York...
www.york.ac.uk
June 13, 2025 at 6:36 AM
@CHEyork @UoY_BizTraining @UniOfYork short courses are run face to face in beautiful York, where you’ll be able to meet and spend time interacting with our faculty of experts as well as network with other participants from the industry, consultancy and academia
www.york.ac.uk/che/courses/...
www.york.ac.uk/che/courses/...
📊Unlock the power of data!📊
Join the Statistical Methods in Economic Evaluation for HTA - Advanced short course at the University of York🚀
📅 9-11 September 2025
📍 York, UK
Secure your spot today! 🔗 york.ac.uk/che/courses/st…#DataSciencece#HealthEconomicsc#HTAT#CEAEA
Join the Statistical Methods in Economic Evaluation for HTA - Advanced short course at the University of York🚀
📅 9-11 September 2025
📍 York, UK
Secure your spot today! 🔗 york.ac.uk/che/courses/st…#DataSciencece#HealthEconomicsc#HTAT#CEAEA
https://york.ac.uk/che/courses/st…
June 4, 2025 at 7:58 AM
📊Unlock the power of data!📊
Join the Statistical Methods in Economic Evaluation for HTA - Advanced short course at the University of York🚀
📅 9-11 September 2025
📍 York, UK
Secure your spot today! 🔗 york.ac.uk/che/courses/st…#DataSciencece#HealthEconomicsc#HTAT#CEAEA
Join the Statistical Methods in Economic Evaluation for HTA - Advanced short course at the University of York🚀
📅 9-11 September 2025
📍 York, UK
Secure your spot today! 🔗 york.ac.uk/che/courses/st…#DataSciencece#HealthEconomicsc#HTAT#CEAEA
interesting article by
@investigate-europe.eu on the price of drugs in the EU, heterogeneity of access across countries and how to negotiate with Pharma www.europeanpressprize.com/article/dead.... Colleagues in York have made important scientific contributions to inform possible negotiations.
@investigate-europe.eu on the price of drugs in the EU, heterogeneity of access across countries and how to negotiate with Pharma www.europeanpressprize.com/article/dead.... Colleagues in York have made important scientific contributions to inform possible negotiations.
Deadly Prices - How Big Pharma Feeds Inequality in Europe - European Press Prize
She is only three years old, but the process is as routine as if she had done it thousands of times before. On this far too warm spring day, Milda, a little girl with a short ponytail, puts on the pin...
www.europeanpressprize.com
May 30, 2025 at 9:21 PM
interesting article by
@investigate-europe.eu on the price of drugs in the EU, heterogeneity of access across countries and how to negotiate with Pharma www.europeanpressprize.com/article/dead.... Colleagues in York have made important scientific contributions to inform possible negotiations.
@investigate-europe.eu on the price of drugs in the EU, heterogeneity of access across countries and how to negotiate with Pharma www.europeanpressprize.com/article/dead.... Colleagues in York have made important scientific contributions to inform possible negotiations.
Reposted by Andrea Manca
This article analyzes how nonexperts perceive AI-generated medical advice, finding that it is often rated as accurate as — or better than — doctor responses, raising concerns about overreliance and potential harm from incorrect guidance. Full article: nejm.ai/43xKDG0
#AI #MedSky #MLSky
#AI #MedSky #MLSky
People Overtrust AI-Generated Medical Advice despite Low Accuracy
This article presents a comprehensive analysis of how artificial intelligence (AI)–generated medical responses are perceived and evaluated by nonexperts. We conducted a study in which a total of 30...
nejm.ai
May 22, 2025 at 1:18 PM
This article analyzes how nonexperts perceive AI-generated medical advice, finding that it is often rated as accurate as — or better than — doctor responses, raising concerns about overreliance and potential harm from incorrect guidance. Full article: nejm.ai/43xKDG0
#AI #MedSky #MLSky
#AI #MedSky #MLSky
Delighted to offer our residential 3-day course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Statistical Methods in Economic Evaluation for HTA - Advanced
Dates - Tuesday 9th - Thursday 11th September 2025
The course will run from 9:00am to 6:00pm BST (GMT+1) on the first day and from 9:30am to 5:00pm on the next two days.
In-person (University of York...
www.york.ac.uk
May 17, 2025 at 6:36 AM
Delighted to offer our residential 3-day course on Statistical Methods in Economic Evaluation for HTA: Advanced Course: September 9-11, 2025!
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Now with an updated program including modern methods for causal inference and machine learning.
www.york.ac.uk/che/courses/...
Reposted by Andrea Manca
[Read] LLM-based relevance assessment still can’t replace
human relevance assessment arxiv.org/pdf/2412.17156. Really interesting paper, challenging the recent idea that one can use LLLM-based relevance assessments to replace human judgements as gold standard,
human relevance assessment arxiv.org/pdf/2412.17156. Really interesting paper, challenging the recent idea that one can use LLLM-based relevance assessments to replace human judgements as gold standard,
April 19, 2025 at 7:16 PM
[Read] LLM-based relevance assessment still can’t replace
human relevance assessment arxiv.org/pdf/2412.17156. Really interesting paper, challenging the recent idea that one can use LLLM-based relevance assessments to replace human judgements as gold standard,
human relevance assessment arxiv.org/pdf/2412.17156. Really interesting paper, challenging the recent idea that one can use LLLM-based relevance assessments to replace human judgements as gold standard,
We are looking to recruit two Research Fellows - Grade 6/7, to work within the Economic Evaluation and Health Technology Assessment team within CHE. Closing Date - 27th April 2025. For further details, visit jobs.york.ac.uk/vacancy/rese...
Jobs - The University of York
jobs.york.ac.uk
March 25, 2025 at 12:28 PM
We are looking to recruit two Research Fellows - Grade 6/7, to work within the Economic Evaluation and Health Technology Assessment team within CHE. Closing Date - 27th April 2025. For further details, visit jobs.york.ac.uk/vacancy/rese...
Reposted by Andrea Manca
Evaluation of Medical Devices for Product Development and Health Technology Assessment Course
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Centre for Health Economics on LinkedIn: 📚 Evaluation of Medical Devices for Product Development and Health…
📚 Evaluation of Medical Devices for Product Development and Health Technology Assessment Course Date - 7th-9th October 2025 Course Leader - Dr Cynthia…
www.linkedin.com
February 21, 2025 at 9:55 AM
Evaluation of Medical Devices for Product Development and Health Technology Assessment Course
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Reposted by Andrea Manca
Delighted to offer our residential 3-day course on Statistical Methods in Economic Evaluation for Health Technology Assessment: Advanced Course: September 9-11, 2025!
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
HealthEconomics.com | A Scientist.com Company on LinkedIn: The Centre for Health Economics University of York is delighted to offer…
The Centre for Health Economics University of York is delighted to offer its residential 3-day short course on Statistical Methods in Economic Evaluation for…
www.linkedin.com
February 21, 2025 at 10:03 AM
Delighted to offer our residential 3-day course on Statistical Methods in Economic Evaluation for Health Technology Assessment: Advanced Course: September 9-11, 2025!
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
'York would be a different city without Rowntree' www.bbc.com/news/article...
How chocolate entrepreneur's values shaped York
Joseph Rowntree's legacy lives on in city where his factory was, 100 years after his death.
www.bbc.com
March 2, 2025 at 11:05 AM
'York would be a different city without Rowntree' www.bbc.com/news/article...
Reposted by Andrea Manca
New example of opportunistic A.I. in medicine
Get a liver diagnosis from an echocardiogram
ai.nejm.org/doi/full/10....
@cedarssinai.bsky.social @ai.nejm.org
Get a liver diagnosis from an echocardiogram
ai.nejm.org/doi/full/10....
@cedarssinai.bsky.social @ai.nejm.org
Opportunistic Screening of Chronic Liver Disease with Deep-Learning–Enhanced Echocardiography
Chronic liver disease (CLD) affects more than 1.5 billion adults, most of whom are asymptomatic and undiagnosed. Echocardiography is broadly performed and visualizes the liver, but this information...
ai.nejm.org
February 27, 2025 at 5:18 PM
New example of opportunistic A.I. in medicine
Get a liver diagnosis from an echocardiogram
ai.nejm.org/doi/full/10....
@cedarssinai.bsky.social @ai.nejm.org
Get a liver diagnosis from an echocardiogram
ai.nejm.org/doi/full/10....
@cedarssinai.bsky.social @ai.nejm.org
Reposted by Andrea Manca
“Why don’t machine learning and large language model evaluations report uncertainty?”
statmodeling.stat.columbia.edu/2025/02/22/w...
statmodeling.stat.columbia.edu/2025/02/22/w...
“Why don’t machine learning and large language model evaluations report uncertainty?” | Statistical Modeling, Causal Inference, and Social Science
statmodeling.stat.columbia.edu
February 22, 2025 at 3:51 PM
“Why don’t machine learning and large language model evaluations report uncertainty?”
statmodeling.stat.columbia.edu/2025/02/22/w...
statmodeling.stat.columbia.edu/2025/02/22/w...
Reposted by Andrea Manca
Our lifestyle and environmental exposures are the predominant influencers of healthy aging and premature mortality, compared with polygenic risk, in the first comprehensive assessment
www.nature.com/articles/s41...
open-access
www.nature.com/articles/s41...
open-access
Integrating the environmental and genetic architectures of aging and mortality - Nature Medicine
Based on a systematic analysis of environmental exposures associated with aging and mortality in the UK Biobank, the relative contributions of such exposures and genetic risk for mortality and a range...
www.nature.com
February 19, 2025 at 2:37 PM
Our lifestyle and environmental exposures are the predominant influencers of healthy aging and premature mortality, compared with polygenic risk, in the first comprehensive assessment
www.nature.com/articles/s41...
open-access
www.nature.com/articles/s41...
open-access
Delighted to offer our residential 3-day course on Statistical Methods in Economic Evaluation for Health Technology Assessment: Advanced Course: September 9-11, 2025!
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
HealthEconomics.com | A Scientist.com Company on LinkedIn: The Centre for Health Economics University of York is delighted to offer…
The Centre for Health Economics University of York is delighted to offer its residential 3-day short course on Statistical Methods in Economic Evaluation for…
www.linkedin.com
February 21, 2025 at 10:03 AM
Delighted to offer our residential 3-day course on Statistical Methods in Economic Evaluation for Health Technology Assessment: Advanced Course: September 9-11, 2025!
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
Discover more at: lnkd.in/eY6UCP_W
Now with an updated program including modern methods for causal inference and machine learning.
Evaluation of Medical Devices for Product Development and Health Technology Assessment Course
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Centre for Health Economics on LinkedIn: 📚 Evaluation of Medical Devices for Product Development and Health…
📚 Evaluation of Medical Devices for Product Development and Health Technology Assessment Course Date - 7th-9th October 2025 Course Leader - Dr Cynthia…
www.linkedin.com
February 21, 2025 at 9:55 AM
Evaluation of Medical Devices for Product Development and Health Technology Assessment Course
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Date - 7th-9th October 2025
Course Leader - Dr Cynthia Iglesias
You can find further details of the course on the University of York website: bit.ly/41lx4cb
Reposted by Andrea Manca
This is a great paper by Mitsuru Igami framing breakthrough AI algorithms in the familiar logic of structural economic model estimation. doi.org/10.1093/ectj...
But by implication, if structural models behave like board games, such as Chess and Go, how high can their degree of realism really be?
But by implication, if structural models behave like board games, such as Chess and Go, how high can their degree of realism really be?
February 21, 2025 at 7:54 AM
This is a great paper by Mitsuru Igami framing breakthrough AI algorithms in the familiar logic of structural economic model estimation. doi.org/10.1093/ectj...
But by implication, if structural models behave like board games, such as Chess and Go, how high can their degree of realism really be?
But by implication, if structural models behave like board games, such as Chess and Go, how high can their degree of realism really be?
Reposted by Andrea Manca
I just wish this cartoon I drew 10+ years ago wasn't so relevant today...
December 14, 2024 at 8:11 PM
I just wish this cartoon I drew 10+ years ago wasn't so relevant today...