Tugce Aktas
@aktast.bsky.social
Max Planck Research Group Leader at MPI for Molecular Genetics, Berlin, Germany. working on:
RNA | Transposable Elements | Genome Evolution
RNA | Transposable Elements | Genome Evolution
Pinned
Tugce Aktas
@aktast.bsky.social
· Jun 30
Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease - Nature Reviews Molecular Cell Biology
Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppressio...
www.nature.com
We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tugce Aktas
IMPRS-BAC Open Call: Current IMPRS student Marcel Wittmund talks about what pursuing a PhD means to him and how the IMPRS program supports his doctoral studies at the MPIMG.
Apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj...
#IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj...
#IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
October 23, 2025 at 3:00 PM
IMPRS-BAC Open Call: Current IMPRS student Marcel Wittmund talks about what pursuing a PhD means to him and how the IMPRS program supports his doctoral studies at the MPIMG.
Apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj...
#IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj...
#IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Reposted by Tugce Aktas
🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
Bioinformatician / Data Scientist (m/f/d)
Bioinformatician / Data scientist position in the Aztekin Lab focusing on Structural Regeneration and support the working group together with the other members
www.mpg.de
September 15, 2025 at 6:58 AM
🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
Reposted by Tugce Aktas
Looking for a master student to help with a superexciting EU-funded project on mRNA metabolism. It'll involve cutting-edge sequencing and imaging techniques as well as computational workflows and modelling - great training opportunity! Get in touch if interested
humantechnopole.it/en/research-...
humantechnopole.it/en/research-...
Legnini Group - Human Technopole
Laboratory for Molecular and Systems Biology of RNA The Legnini Group at Human Technopole combines molecular and systems biology approaches to study gene regulation. We use synthetic biology and opt...
humantechnopole.it
September 10, 2025 at 7:51 AM
Looking for a master student to help with a superexciting EU-funded project on mRNA metabolism. It'll involve cutting-edge sequencing and imaging techniques as well as computational workflows and modelling - great training opportunity! Get in touch if interested
humantechnopole.it/en/research-...
humantechnopole.it/en/research-...
Transposon enthusiats: you don't want to miss this story.
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 9, 2025 at 10:22 AM
Transposon enthusiats: you don't want to miss this story.
Reposted by Tugce Aktas
New Online! Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease
Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease
Nature Reviews Molecular Cell Biology, Published online: 30 June 2025; doi:10.1038/s41580-025-00867-8Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppression and regulate endogenous genes in development and disease, and emerging therapeutic strategies that exploit TE derepression.
bit.ly
June 30, 2025 at 12:39 PM
New Online! Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease
We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease - Nature Reviews Molecular Cell Biology
Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppressio...
www.nature.com
June 30, 2025 at 1:12 PM
We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tugce Aktas
📢 Don't miss!
Wayo Matsushima of École polytechnique fédérale de Lausanne (EPFL) will speak at our #DahlemColloquium!
📜 Gene regulatory evolution driven by transposable elements and their controllers
📆 20. JUN, 11:00 AM (CET)
📍MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41978...
Wayo Matsushima of École polytechnique fédérale de Lausanne (EPFL) will speak at our #DahlemColloquium!
📜 Gene regulatory evolution driven by transposable elements and their controllers
📆 20. JUN, 11:00 AM (CET)
📍MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41978...
June 13, 2025 at 9:16 AM
📢 Don't miss!
Wayo Matsushima of École polytechnique fédérale de Lausanne (EPFL) will speak at our #DahlemColloquium!
📜 Gene regulatory evolution driven by transposable elements and their controllers
📆 20. JUN, 11:00 AM (CET)
📍MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41978...
Wayo Matsushima of École polytechnique fédérale de Lausanne (EPFL) will speak at our #DahlemColloquium!
📜 Gene regulatory evolution driven by transposable elements and their controllers
📆 20. JUN, 11:00 AM (CET)
📍MPIMG, Berlin
🔗 www.molgen.mpg.de/events/41978...
Reposted by Tugce Aktas
In @nature.com Yaotian Zhang and @henriniskanen.bsky.social from the Hnisz Lab discovered a micropeptide, the "Killswitch," which alters the physical state of biomolecules in condensates. This tool solidifies dynamic, liquid-like droplets, affecting their function.
--> www.molgen.mpg.de/4884827
--> www.molgen.mpg.de/4884827
June 6, 2025 at 8:28 AM
In @nature.com Yaotian Zhang and @henriniskanen.bsky.social from the Hnisz Lab discovered a micropeptide, the "Killswitch," which alters the physical state of biomolecules in condensates. This tool solidifies dynamic, liquid-like droplets, affecting their function.
--> www.molgen.mpg.de/4884827
--> www.molgen.mpg.de/4884827
Congratulations neighbors!
We are very happy to be part of this story and looking forward to the future work we'll be doing with the Hnisz lab 😉
We are very happy to be part of this story and looking forward to the future work we'll be doing with the Hnisz lab 😉
What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments play a key role, and can be probed by a micropeptide killswitch in live cells. www.nature.com/articles/s41... in @nature.com with @yaotianzhang.bsky.social Denes Hnisz & team.
www.nature.com
June 4, 2025 at 3:38 PM
Congratulations neighbors!
We are very happy to be part of this story and looking forward to the future work we'll be doing with the Hnisz lab 😉
We are very happy to be part of this story and looking forward to the future work we'll be doing with the Hnisz lab 😉
Reposted by Tugce Aktas
The awesome Helene Kretzmer and I are looking to recruit a join computational PhD student. Applications will be evaluated on a rolling basis, so don't wait! Any questions get in touch. We are looking forward.
April 28, 2025 at 2:06 PM
The awesome Helene Kretzmer and I are looking to recruit a join computational PhD student. Applications will be evaluated on a rolling basis, so don't wait! Any questions get in touch. We are looking forward.
Reposted by Tugce Aktas
How to find binding sites or your favorite #RNA binding protein?
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
iCLIP2, mapping protein-RNA interactions: from A to Z
RNA is increasingly recognized as a key therapeutic target , driving the development of RNA-based therapeutics for a broad spectrum of diseases. RNA-binding proteins (RBPs) play a fundamental ro…
meetings.embo.org
March 26, 2025 at 7:58 AM
How to find binding sites or your favorite #RNA binding protein?
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
Reposted by Tugce Aktas
Don't miss the first edition of the CSH-Asia meeting on "The Repetitive and Mobile Genome" taking place in Suzhou, China.
📅 Abstract submission deadline extended: Feb 21, 2025
👉 www.csh-asia.org?content/2544
#transposon #mobileDNA #TEsky
📅 Abstract submission deadline extended: Feb 21, 2025
👉 www.csh-asia.org?content/2544
#transposon #mobileDNA #TEsky
February 7, 2025 at 4:43 PM
Don't miss the first edition of the CSH-Asia meeting on "The Repetitive and Mobile Genome" taking place in Suzhou, China.
📅 Abstract submission deadline extended: Feb 21, 2025
👉 www.csh-asia.org?content/2544
#transposon #mobileDNA #TEsky
📅 Abstract submission deadline extended: Feb 21, 2025
👉 www.csh-asia.org?content/2544
#transposon #mobileDNA #TEsky
Reposted by Tugce Aktas
CSH Asia is organising its first transposon meeting. Don't miss out on some great science and a fantastic trip. Abstract deadline fast approaching.
www.csh-asia.org?content/2544
www.csh-asia.org?content/2544
January 9, 2025 at 11:35 AM
CSH Asia is organising its first transposon meeting. Don't miss out on some great science and a fantastic trip. Abstract deadline fast approaching.
www.csh-asia.org?content/2544
www.csh-asia.org?content/2544
Reposted by Tugce Aktas
🎉 Excited to announce job openings in our new lab @mpi-bio-fml.bsky.social in Tübingen!🇩🇪Looking for enthusiastic colleagues to explore regeneration together! We have positions for:
🔬 Research Technician
💻 Bioinformatician
🎓 PhD Studentship
🧪🔬📖 Postdocs
Details and links below👇
🔬 Research Technician
💻 Bioinformatician
🎓 PhD Studentship
🧪🔬📖 Postdocs
Details and links below👇
December 20, 2024 at 8:33 AM
🎉 Excited to announce job openings in our new lab @mpi-bio-fml.bsky.social in Tübingen!🇩🇪Looking for enthusiastic colleagues to explore regeneration together! We have positions for:
🔬 Research Technician
💻 Bioinformatician
🎓 PhD Studentship
🧪🔬📖 Postdocs
Details and links below👇
🔬 Research Technician
💻 Bioinformatician
🎓 PhD Studentship
🧪🔬📖 Postdocs
Details and links below👇
Reposted by Tugce Aktas
The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring?
Apply before Feb 15th
📌
Apply before Feb 15th
📌
November 28, 2024 at 7:21 PM
The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring?
Apply before Feb 15th
📌
Apply before Feb 15th
📌